acetaminophen has been researched along with Inflammation, Endodontic in 21 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this double-blind clinical trial was to compare the effect of preoperative tramadol 50 mg, tramadol 100 mg, ibuprofen 600 mg, ibuprofen 600 mg/acetaminophen 1000 mg or placebo 60 min before the administration of inferior alveolar nerve blocks (IANB) of mandibular teeth in patients experiencing symptomatic irreversible pulpitis (SIP)." | 9.69 | Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. ( Badr, AE; Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023) |
| "Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis." | 9.22 | Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016) |
| "The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of the administration of the combination acetaminophen/hydrocodone on the anesthetic success of mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis." | 9.19 | Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. ( Beck, M; Drum, M; Fullmer, S; Nusstein, J; Reader, A, 2014) |
| "The purpose of this prospective randomized, double-blind, placebo-controlled study was to determine the effects of a combination dose of 1000 mg acetaminophen/10 mg hydrocodone on cold pulpal testing in patients experiencing symptomatic irreversible pulpitis." | 9.19 | Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study. ( Drum, M; Fowler, S; Fullmer, S; Reader, A, 2014) |
| "The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of the administration of the combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve (IAN) block in patients with symptomatic irreversible pulpitis." | 9.15 | Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. ( Beck, M; Drum, M; Nusstein, J; Reader, A; Simpson, M, 2011) |
| "The purpose of this double-blind clinical trial was to compare the effect of preoperative tramadol 50 mg, tramadol 100 mg, ibuprofen 600 mg, ibuprofen 600 mg/acetaminophen 1000 mg or placebo 60 min before the administration of inferior alveolar nerve blocks (IANB) of mandibular teeth in patients experiencing symptomatic irreversible pulpitis (SIP)." | 5.69 | Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. ( Badr, AE; Elnaghy, AM; Elsaka, SE; Elshazli, AH, 2023) |
| " The aim of this study was to assess the effect of 2 commonly used analgesics namely ibuprofen and acetaminophen on the cold and electric pulp test (EPT) results in participants with symptomatic irreversible pulpitis (SIP)." | 5.69 | Evaluation of the Effect of Common Analgesics on Pulpal Sensibility Tests: A Clinical Trial. ( Asadi, Y; Dibaji, F; Kharazifard, M; Khavanin, N; Sooratgar, A, 2023) |
| " The purpose of this study was to compare the efficacy of intranasal ketorolac (Sprix; Egalet US Inc, Wayne, PA) with a combination of ibuprofen/acetaminophen in an acute pain model of untreated endodontic patients experiencing moderate to severe pain and symptomatic apical periodontitis." | 5.30 | Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation. ( Balzer, S; Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Watts, K, 2019) |
| "The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials." | 5.22 | Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016) |
| "Although liposomal bupivacaine had some effect on soft tissue anesthesia, it did not reduce pain to manageable clinical levels in patients presenting with untreated, symptomatic irreversible pulpitis." | 5.22 | Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial. ( Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A, 2016) |
| "The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of the administration of the combination acetaminophen/hydrocodone on the anesthetic success of mandibular posterior teeth in patients experiencing symptomatic irreversible pulpitis." | 5.19 | Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study. ( Beck, M; Drum, M; Fullmer, S; Nusstein, J; Reader, A, 2014) |
| "The purpose of this prospective randomized, double-blind, placebo-controlled study was to determine the effects of a combination dose of 1000 mg acetaminophen/10 mg hydrocodone on cold pulpal testing in patients experiencing symptomatic irreversible pulpitis." | 5.19 | Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study. ( Drum, M; Fowler, S; Fullmer, S; Reader, A, 2014) |
| " In this double-blind clinical trial, 100 patients who had anterior or premolar teeth with irreversible pulpitis without any signs and symptoms of acute or chronic apical periodontitis and moderate to severe pain were divided by balanced block random allocation into four groups of 25 each, a control group receiving a placebo medication, and three experimental groups receiving a single dose of either Tramadol (100 mg), Novafen (325 mg of paracetamol, 200 mg ibuprofen and 40 mg caffeine anhydrous) or Naproxen (500 mg) immediately after the first appointment where the pulp was removed, and the canals were fully prepared." | 5.16 | Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial. ( Abbott, PV; Asgar, K; Delvarani, A; Karamifar, K; Khabazi, H; Kharazifard, MJ; Lotfi, M; Mehrvarzfar, P; Saghiri, MA, 2012) |
| "The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of the administration of the combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve (IAN) block in patients with symptomatic irreversible pulpitis." | 5.15 | Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. ( Beck, M; Drum, M; Nusstein, J; Reader, A; Simpson, M, 2011) |
| "The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis." | 5.09 | Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol. ( Beck, M; Gallatin, E; Nist, R; Reader, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Elnaghy, AM | 1 |
| Elshazli, AH | 1 |
| Badr, AE | 1 |
| Elsaka, SE | 1 |
| Sooratgar, A | 1 |
| Khavanin, N | 1 |
| Dibaji, F | 1 |
| Asadi, Y | 1 |
| Kharazifard, M | 1 |
| Miroshnychenko, A | 1 |
| Azab, M | 1 |
| Ibrahim, S | 1 |
| Roldan, Y | 1 |
| Diaz Martinez, JP | 1 |
| Tamilselvan, D | 1 |
| He, L | 1 |
| Urquhart, O | 1 |
| Tampi, M | 1 |
| Polk, DE | 1 |
| Moore, PA | 1 |
| Hersh, EV | 1 |
| Carrasco-Labra, A | 1 |
| Brignardello-Petersen, R | 1 |
| Gallinari, MO | 1 |
| Cintra, LTÂ | 1 |
| Benetti, F | 1 |
| Rahal, V | 1 |
| Ervolino, E | 1 |
| Briso, ALF | 1 |
| Watts, K | 1 |
| Balzer, S | 1 |
| Drum, M | 5 |
| Nusstein, J | 4 |
| Reader, A | 6 |
| Fowler, S | 3 |
| Beck, M | 5 |
| Dabuleanu, M | 1 |
| Fullmer, S | 2 |
| Fedorowicz, Z | 2 |
| van Zuuren, EJ | 2 |
| Farman, AG | 2 |
| Agnihotry, A | 2 |
| Al-Langawi, JH | 2 |
| Williamson, AE | 1 |
| Elzaki, WM | 1 |
| Abubakr, NH | 1 |
| Ziada, HM | 1 |
| Ibrahim, YE | 1 |
| Hoskin, E | 1 |
| Veitz-Keenan, A | 1 |
| Bultema, K | 1 |
| Simpson, M | 1 |
| Mehrvarzfar, P | 1 |
| Abbott, PV | 1 |
| Saghiri, MA | 1 |
| Delvarani, A | 1 |
| Asgar, K | 1 |
| Lotfi, M | 1 |
| Karamifar, K | 1 |
| Kharazifard, MJ | 1 |
| Khabazi, H | 1 |
| Modaresi, J | 1 |
| Dianat, O | 1 |
| Mozayeni, MA | 1 |
| Ianiro, SR | 1 |
| Jeansonne, BG | 1 |
| McNeal, SF | 1 |
| Eleazer, PD | 1 |
| Thomas, MB | 1 |
| Moran, N | 1 |
| Smart, K | 1 |
| Crean, S | 1 |
| Gallatin, E | 1 |
| Nist, R | 1 |
| Bloomquist, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Preoperative Oral Tramadol on the Anaesthetic Efficacy of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind, Controlled Study[NCT04961268] | 250 participants (Actual) | Interventional | 2020-06-01 | Completed | |||
| Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337] | Phase 2 | 170 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Effect of Preoperative Acetaminophen-Codeine-Caffeine Combination on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis: Randomized Double-blind Controlled Trial[NCT04202406] | 69 participants (Actual) | Interventional | 2021-01-09 | Completed | |||
| The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761] | 20 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | |||
| Comparison of the Efficacy of Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine for Management of Post-endodontic Pain in Posterior Teeth[NCT03006107] | 26 participants (Anticipated) | Interventional | 2016-12-31 | Not yet recruiting | |||
| Efficacy of Preoperative Diclofenac Potassium- Acetaminophen Combination on Anesthetic Success in Patients With Symptomatic Irreversible Pulpitis: a Randomized Controlled Trial[NCT04593160] | 72 participants (Anticipated) | Interventional | 2021-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for acetaminophen and Inflammation, Endodontic
| Article | Year |
|---|---|
Analgesics for the management of acute dental pain in the pediatric population: A systematic review and meta-analysis.
Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Pulpitis | 2023 |
Antibiotic use for irreversible pulpitis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Humans; Ibuprofen; Pain Measurement; | 2013 |
Antibiotic use for irreversible pulpitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Female; Humans; Ibuprofen; Ma | 2016 |
12 trials available for acetaminophen and Inflammation, Endodontic
| Article | Year |
|---|---|
Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
Topics: Acetaminophen; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Ibuprofen; Lidoc | 2023 |
Evaluation of the Effect of Common Analgesics on Pulpal Sensibility Tests: A Clinical Trial.
Topics: Acetaminophen; Analgesics; Dental Pulp; Humans; Ibuprofen; Pulpitis | 2023 |
Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation.
Topics: Acetaminophen; Acute Pain; Administration, Intranasal; Administration, Oral; Adult; Dental Pulp Necr | 2019 |
Effect of preoperative acetaminophen/hydrocodone on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Local; | 2014 |
Does acetaminophen/hydrocodone affect cold pulpal testing in patients with symptomatic irreversible pulpitis? A prospective, randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, | 2016 |
Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bicuspid; Carticaine; Dental Pul | 2011 |
Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bicuspid; Carticaine; Dental Pul | 2011 |
Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bicuspid; Carticaine; Dental Pul | 2011 |
Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bicuspid; Carticaine; Dental Pul | 2011 |
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth.
Topics: Acetaminophen; Administration, Oral; Analgesics; Analysis of Variance; Anesthesia, Dental; Anesthesi | 2006 |
The effect of preoperative acetaminophen or a combination of acetaminophen and Ibuprofen on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Epidemiologic Methods; Female; Humans; Ibuprof | 2007 |
The effect of preoperative acetaminophen or a combination of acetaminophen and Ibuprofen on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Epidemiologic Methods; Female; Humans; Ibuprof | 2007 |
The effect of preoperative acetaminophen or a combination of acetaminophen and Ibuprofen on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Epidemiologic Methods; Female; Humans; Ibuprof | 2007 |
The effect of preoperative acetaminophen or a combination of acetaminophen and Ibuprofen on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Epidemiologic Methods; Female; Humans; Ibuprof | 2007 |
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-I | 2000 |
6 other studies available for acetaminophen and Inflammation, Endodontic
| Article | Year |
|---|---|
Pulp response of rats submitted to bleaching and the use of different anti-inflammatory drugs.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Calcitonin Gene-Related Peptide; Dental Pulp; Dise | 2019 |
Pulpitis (reversible/irreversible).
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Dental Restoration, Permanent; Humans; Ibupr | 2013 |
A Combination of Acetaminophen/Hydrocodone may not Affect Cold Pulpal Testing in Patients With Symptomatic Irreversible Pulpitis.
Topics: Acetaminophen; Double-Blind Method; Humans; Hydrocodone; Mandibular Nerve; Pulpitis | 2015 |
Antibiotics are not useful to reduce pain associated with irreversible pulpitis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Double-Blind Method; Humans; Pulpiti | 2016 |
Paracetamol overdose as a result of dental pain requiring medical treatment - two case reports.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antidotes; Chemical and Drug Ind | 2007 |
Pain control in endodontics.
Topics: Acetaminophen; Analgesics; Aspirin; Cellulitis; Codeine; Dextropropoxyphene; Humans; Nausea; Pain; P | 1979 |