acetaminophen has been researched along with Infant, Premature, Diseases in 22 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Infant, Premature, Diseases: Diseases that occur in PREMATURE INFANTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Preterm (< 37 weeks) and term (37-41 weeks) infants received a single dose of propacetamol in the first 24 hours of life when they had minor, painful procedures or as additional treatment in infants receiving opioids." | 3.72 | Pharmacokinetics of single dose intravenous propacetamol in neonates: effect of gestational age. ( Allegaert, K; Debeer, A; Devlieger, H; Pluim, MA; Tibboel, D; Van der Marel, CD; Van Lingen, RA; Vanhole, C, 2004) |
| " We studied whether the use of paracetamol had an adverse influence on neonatal adaptation and the outcomes of infants during the first hospitalization." | 1.72 | Paracetamol preceding very preterm birth: Is it safe? ( Aikio, O; Hallman, M; Laitala, A; Saarela, T; Vääräsmäki, M, 2022) |
| "A population pharmacokinetic analysis of 943 paracetamol observations from 158 neonates (27-45 weeks' postmenstrual age (PMA)) was undertaken using non-linear mixed effects models." | 1.37 | The pharmacokinetics of intravenous paracetamol in neonates: size matters most. ( Allegaert, K; Anderson, BJ; Palmer, GM, 2011) |
| " A population pharmacokinetic analysis of paracetamol (acetaminophen) time-concentration profiles in 48 neonates was undertaken using non-linear mixed-effects models." | 1.32 | Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates. ( Allegaert, K; Anderson, BJ; de Hoon, J; Debeer, A; Devlieger, H; Naulaers, G; Tibboel, D; Verbesselt, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 13 (59.09) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Santoro, KL | 1 |
| Yakah, W | 1 |
| Singh, P | 1 |
| Ramiro-Cortijo, D | 1 |
| Medina-Morales, E | 1 |
| Freedman, SD | 1 |
| Martin, CR | 1 |
| Laitala, A | 1 |
| Saarela, T | 2 |
| Vääräsmäki, M | 1 |
| Hallman, M | 2 |
| Aikio, O | 2 |
| Höck, M | 1 |
| Sappler, M | 1 |
| Hammerl, M | 1 |
| Griesmaier, E | 1 |
| Ndayisaba, JP | 1 |
| Schreiner, C | 1 |
| Pupp-Peglow, U | 1 |
| Kiechl-Kohlendorfer, U | 1 |
| Neubauer, V | 1 |
| Staunton, D | 1 |
| El-Khuffash, A | 1 |
| Juujärvi, S | 1 |
| Huang, X | 1 |
| Wang, F | 1 |
| Wang, K | 1 |
| Bin-Nun, A | 2 |
| Fink, D | 1 |
| Mimouni, FB | 1 |
| Algur, N | 1 |
| Hammerman, C | 2 |
| El-Farrash, RA | 1 |
| El Shimy, MS | 1 |
| El-Sakka, AS | 1 |
| Ahmed, MG | 1 |
| Abdel-Moez, DG | 1 |
| Pavlek, L | 1 |
| Kraft, M | 1 |
| Simmons, C | 1 |
| Ryan, M | 1 |
| Prusakov, P | 1 |
| Campbell, A | 1 |
| Brandehoff, N | 1 |
| Ng, PC | 1 |
| Russell, J | 1 |
| Ciciora, SL | 1 |
| Fathi, O | 1 |
| Lei, C | 1 |
| Liu, H | 1 |
| Wang, H | 1 |
| Liu, C | 1 |
| Ozdemir, OM | 1 |
| Doğan, M | 1 |
| Küçüktaşçı, K | 1 |
| Ergin, H | 1 |
| Sahin, O | 1 |
| Kessel, I | 1 |
| Waisman, D | 1 |
| Lavie-Nevo, K | 1 |
| Golzman, M | 1 |
| Lorber, A | 1 |
| Rotschild, A | 1 |
| Terrin, G | 1 |
| Conte, F | 1 |
| Scipione, A | 1 |
| Bacchio, E | 1 |
| Conti, MG | 1 |
| Ferro, R | 1 |
| Ventriglia, F | 1 |
| De Curtis, M | 1 |
| Allegaert, K | 4 |
| Palmer, GM | 1 |
| Anderson, BJ | 2 |
| Porta, R | 1 |
| Sánchez, L | 1 |
| Nicolás, M | 1 |
| García, C | 1 |
| Martínez, M | 1 |
| Kaplan, M | 1 |
| Oncel, MY | 2 |
| Yurttutan, S | 2 |
| Uras, N | 2 |
| Altug, N | 2 |
| Ozdemir, R | 1 |
| Ekmen, S | 1 |
| Erdeve, O | 2 |
| Dilmen, U | 2 |
| Arayicı, S | 1 |
| SILVERBERG, M | 1 |
| DESFORGES, J | 1 |
| GELLIS, S | 1 |
| Van der Marel, CD | 1 |
| Debeer, A | 2 |
| Pluim, MA | 1 |
| Van Lingen, RA | 1 |
| Vanhole, C | 1 |
| Tibboel, D | 3 |
| Devlieger, H | 3 |
| Verbesselt, R | 2 |
| de Hoon, J | 2 |
| Naulaers, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between the Effect of Oral Paracetamol Versus Oral Ibuprofen in the Treatment of Patent Ductus Arteriosus in Preterm and Low Birth Weight Infants[NCT03265782] | Phase 4 | 30 participants (Actual) | Interventional | 2015-06-30 | Active, not recruiting | ||
| Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus in Premature Infants: A Pilot Study[NCT03103022] | Phase 1 | 20 participants (Actual) | Interventional | 2017-06-12 | Completed | ||
| Paracetamol Versus Ibuprofen for Patent Ductus Arteriosus Closure in Preterm Infants. A Prospective, Randomized, Controlled, Double Blind, Multicenter Clinical Trial.[NCT02056223] | Phase 2/Phase 3 | 120 participants (Anticipated) | Interventional | 2017-01-09 | Suspended (stopped due to We enrolled only 53 patients) | ||
| Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants[NCT01755728] | Phase 3 | 19 participants (Actual) | Interventional | 2013-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for acetaminophen and Infant, Premature, Diseases
| Article | Year |
|---|---|
Paracetamol versus ibuprofen for the treatment of patent ductus arteriosus in preterm neonates: a meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Infant, Newborn; Infant, Premat | 2018 |
Lack of toxicity after paracetamol overdose in a extremely preterm neonate.
Topics: Abdominal Pain; Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemical and Drug Induced L | 2012 |
Managing the patent ductus arteriosus in the premature neonate: a new look at what we thought we knew.
Topics: Acetaminophen; Biomarkers; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echocardiogr | 2012 |
3 trials available for acetaminophen and Infant, Premature, Diseases
| Article | Year |
|---|---|
Trial of paracetamol for premature newborns: five-year follow-up.
Topics: Acetaminophen; Child; Ductus Arteriosus, Patent; Follow-Up Studies; Humans; Infant; Infant, Newborn; | 2022 |
Efficacy and safety of oral paracetamol versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Case-Control Studies; Double-Blind Method; Ductus Arteriosus, P | 2019 |
A different first-choice drug in the medical management of patent ductus arteriosus: oral paracetamol.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Ductus Arteriosus, Patent; Humans; In | 2013 |
16 other studies available for acetaminophen and Infant, Premature, Diseases
| Article | Year |
|---|---|
Acetaminophen and Xenobiotic Metabolites in Human Milk and the Development of Bronchopulmonary Dysplasia and Retinopathy of Prematurity in a Cohort of Extremely Preterm Infants.
Topics: Acetaminophen; Bronchopulmonary Dysplasia; Cohort Studies; Female; Humans; Infant; Infant, Extremely | 2022 |
Paracetamol preceding very preterm birth: Is it safe?
Topics: Acetaminophen; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseas | 2022 |
Prophylactic low-dose paracetamol for ductal closure and neurodevelopmental outcome in very preterm infants.
Topics: Acetaminophen; Child; Child, Preschool; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant; Infant | 2023 |
The unintended consequences of acetaminophen use for ductal closure in premature infants.
Topics: Acetaminophen; Animals; Animals, Newborn; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, | 2020 |
Paracetamol Serum Concentrations in Neonates Treated Enterally for Ductal Closure: A Pilot Study.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Ductus Arteriosus, Patent; Humans; In | 2018 |
Acetaminophen and Acetylsalicylic Acid Exposure in a Preterm Infant after Maternal Overdose.
Topics: Acetaminophen; Antidepressive Agents; Antidotes; Aspirin; Cystine; Drug Overdose; Female; Humans; In | 2019 |
Effectiveness and Renal Functions Safety of Treatments Used for Neonates with Patent Ductus Arteriosus: A Prospective Cohort Study.
Topics: Acetaminophen; Acute Kidney Injury; China; Cohort Studies; Ductus Arteriosus, Patent; Female; Humans | 2019 |
Paracetamol therapy for patent ductus arteriosus in premature infants: a chance before surgical ligation.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Cardiac Surgical Procedures; Dose-Res | 2014 |
Paracetamol effectiveness, safety and blood level monitoring during patent ductus arteriosus closure: a case series.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Infant, | 2014 |
Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Birth Weight; Dose-Response Relationship, Drug; Ductus Arte | 2014 |
The pharmacokinetics of intravenous paracetamol in neonates: size matters most.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Body Weight; Drug Administration Schedule; Gestational Age; | 2011 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Contraindications; Drug Resistance; Ductus Arteriosus, Pate | 2013 |
MECHANISMS UNDERLYING VITAMIN K INDUCED HYPERBILIRUBINEMIA IN PREMATURE INFANTS.
Topics: Acetaminophen; Acetanilides; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Bilirubin; Erythroc | 1963 |
Pharmacokinetics of single dose intravenous propacetamol in neonates: effect of gestational age.
Topics: Acetaminophen; Analgesia; Analgesics; Betamethasone; Birth Weight; Female; Gestational Age; Half-Lif | 2004 |
Cerebrospinal fluid pharmacokinetics of paracetamol after intravenous propacetamol in a former preterm infant.
Topics: Acetaminophen; Analgesics; Humans; Hydrocephalus; Infant, Newborn; Infant, Premature, Diseases; Infu | 2004 |
Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Body Weight; Clinical Trials as Topic; Drug Ad | 2004 |