Page last updated: 2024-10-22

acetaminophen and Infant, Newborn, Diseases

acetaminophen has been researched along with Infant, Newborn, Diseases in 13 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.

Research Excerpts

ExcerptRelevanceReference
"Salicylates have been the most widely studied of the nonnarcotic analgesics in pregnancy, and in the last 20 years evidence has accumulated indicating that their ingestion in pregnancy may have adverse effects on the mother and her child."8.76Maternal and fetal effects of acetaminophen and salicylates in pregnancy. ( Collins, E, 1981)
" The effects of acetaminophen in pregnancy and in the newborn have not been studied extensively; when ingested in usual therapeutic doses, the available data have shown no adverse effects."7.66Effects of aspirin and acetaminophen in pregnancy and in the newborn. ( Rudolph, AM, 1981)
"Salicylates have been the most widely studied of the nonnarcotic analgesics in pregnancy, and in the last 20 years evidence has accumulated indicating that their ingestion in pregnancy may have adverse effects on the mother and her child."4.76Maternal and fetal effects of acetaminophen and salicylates in pregnancy. ( Collins, E, 1981)
" On day 2 post partum, mothers were questioned regarding maternal risk factors, including the use of either aspirin or acetaminophen during the last week of pregnancy."3.66Neonatal intracranial hemorrhage and maternal use of aspirin. ( Braithwaite, WR; Guggenheim, MA; Johnson, ML; Peterson, RG; Rumack, BH; Rumack, CM, 1981)
" The effects of acetaminophen in pregnancy and in the newborn have not been studied extensively; when ingested in usual therapeutic doses, the available data have shown no adverse effects."3.66Effects of aspirin and acetaminophen in pregnancy and in the newborn. ( Rudolph, AM, 1981)
"To assess the risk of significant adverse events in premature infants receiving the novel 4-component group B meningococcal vaccine (4CMenB) with their routine immunisations at 2 months of age."1.51Safety of meningococcal group B vaccination in hospitalised premature infants. ( Beebeejaun, K; Braccio, S; Clarke, P; Heath, PT; Kadambari, S; Kent, A; Ladhani, S, 2019)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Bin-Nun, A1
Abu-Omar, R1
Shchors, I1
Mimouni, F1
Hammerman, C1
Kent, A1
Beebeejaun, K1
Braccio, S1
Kadambari, S1
Clarke, P1
Heath, PT1
Ladhani, S1
Allegaert, K1
Mian, P1
Lapillonne, A1
van den Anker, JN1
Leeder, JS1
HARLEY, JD1
FARRAR, JF1
GRAY, JB1
DUNLOP, IC1
Beattie, JO1
Chen, CP1
MacDonald, TH1
Golden, NL1
King, KC1
Sokol, RJ1
Collins, E1
Rumack, CM1
Guggenheim, MA1
Rumack, BH1
Peterson, RG1
Johnson, ML1
Braithwaite, WR1
Rudolph, AM1
Sancewicz-Pach, K1
Chmiest, W1
Lichota, E1
Char, VC1
Chandra, R1
Fletcher, AB1
Avery, GB1
Gmyrek, D1
Kalz, M1
Pietsch, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants[NCT01755728]Phase 319 participants (Actual)Interventional2013-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetaminophen and Infant, Newborn, Diseases

ArticleYear
Maternal and fetal effects of acetaminophen and salicylates in pregnancy.
    Obstetrics and gynecology, 1981, Volume: 58, Issue:5 Suppl

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Birth Weight; Chemical and Drug Induced Liver I

1981

Other Studies

12 other studies available for acetaminophen and Infant, Newborn, Diseases

ArticleYear
Does Early Neonatal Thrombocytopenia Affect Ductal Therapeutic Response to Acetaminophen in Preterm Neonates?
    American journal of perinatology, 2022, Volume: 29, Issue:14

    Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant, Newb

2022
Safety of meningococcal group B vaccination in hospitalised premature infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2019, Volume: 104, Issue:2

    Topics: Acetaminophen; Anti-Bacterial Agents; Body Temperature; C-Reactive Protein; England; Humans; Infant,

2019
Maternal paracetamol intake and fetal ductus arteriosus constriction or closure: a case series analysis.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Constriction, Pathologic; Ductus Arteriosus; Female; Humans

2019
Developmental pharmacogenetics: a general paradigm for application to neonatal pharmacology and toxicology.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzhydryl Compounds; Environmental Pollutants; Female; Gas

2009
AROMATIC DRUGS AND CONGENITAL CATARACTS.
    Lancet (London, England), 1964, Feb-29, Volume: 1, Issue:7331

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Acetazolamide; Anti-Bacterial Agents; Cardiovascular Age

1964
Neonatal distalgesic poisoning.
    Lancet (London, England), 1981, Jul-04, Volume: 2, Issue:8236

    Topics: Acetaminophen; Apnea; Dextropropoxyphene; Drug Combinations; Humans; Infant, Newborn; Infant, Newbor

1981
Propoxyphene and acetaminophen. Possible effects on the fetus.
    Clinical pediatrics, 1982, Volume: 21, Issue:12

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetaminophen; Dextropropoxyphene; Drug Therap

1982
Neonatal intracranial hemorrhage and maternal use of aspirin.
    Obstetrics and gynecology, 1981, Volume: 58, Issue:5 Suppl

    Topics: Acetaminophen; Aspirin; Cerebral Hemorrhage; Female; Gestational Age; Humans; Infant, Low Birth Weig

1981
Effects of aspirin and acetaminophen in pregnancy and in the newborn.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Aspirin; Blood Platelets; Female; Fetus; Humans

1981
Suicidal paracetamol poisoning of a pregnant woman just before a delivery.
    Przeglad lekarski, 1999, Volume: 56, Issue:6

    Topics: Acetaminophen; Adult; Aspartate Aminotransferases; Drug Overdose; Female; Humans; Infant, Newborn; I

1999
Letter: Polyhydramnios and neonatal renal failure--a possible association with maternal acetaminophen ingestion.
    The Journal of pediatrics, 1975, Volume: 86, Issue:4

    Topics: Acetaminophen; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kidney Failure, C

1975
[Medicamentous prevention of hyperbilirubinemia of the newborn. II. Influence of the inductor phenylbutazone on loading with paracetamol in newborn].
    Das Deutsche Gesundheitswesen, 1971, Aug-19, Volume: 26, Issue:34

    Topics: Acetaminophen; Child; Chromatography, Thin Layer; Enzyme Induction; Glucuronates; Humans; Hyperbilir

1971