acetaminophen has been researched along with Idiopathic Parkinson Disease in 16 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was a dose-response relationship between tablets of ibuprofen taken per week and PD risk (p trend = 0." | 6.47 | Use of ibuprofen and risk of Parkinson disease. ( Ascherio, A; Chen, H; Gao, X; Schwarzschild, MA, 2011) |
| " There was a dose-response relationship between tablets of ibuprofen taken per week and PD risk (p trend = 0." | 2.47 | Use of ibuprofen and risk of Parkinson disease. ( Ascherio, A; Chen, H; Gao, X; Schwarzschild, MA, 2011) |
| "Nonaspirin NSAID use was associated with a higher risk in women and a lower risk in men." | 1.33 | Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease. ( García Rodríguez, LA; Hernán, MA; Logroscino, G, 2006) |
| "4." | 1.32 | An investigation into the inter-relationships of sulphur xeno-biotransformation pathways in Parkinson's and motor neurone diseases. ( Steventon, GB; Waring, RH; Williams, AC, 2003) |
| "We studied 68 patients with Parkinson's disease (PD) with probe drugs to determine whether a defect in metabolism might be an etiologic factor and found no difference between patients and controls in their ability to form the 4-hydroxy metabolite of debrisoquin." | 1.28 | Xenobiotic metabolism in Parkinson's disease. ( Heafield, MT; Steventon, GB; Waring, RH; Williams, AC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bohler, S | 1 |
| Liu, X | 1 |
| Krauskopf, J | 1 |
| Caiment, F | 1 |
| Aubrecht, J | 1 |
| Nicolaes, GAF | 1 |
| Kleinjans, JCS | 1 |
| Briedé, JJ | 1 |
| Locke, CJ | 1 |
| Fox, SA | 1 |
| Caldwell, GA | 1 |
| Caldwell, KA | 1 |
| Gao, X | 1 |
| Chen, H | 3 |
| Schwarzschild, MA | 3 |
| Ascherio, A | 3 |
| Zhang, SM | 1 |
| Hernán, MA | 2 |
| Willett, WC | 1 |
| Colditz, GA | 1 |
| Speizer, FE | 1 |
| Steventon, GB | 3 |
| Waring, RH | 3 |
| Williams, AC | 3 |
| Jacobs, E | 1 |
| McCullough, ML | 1 |
| Calle, EE | 1 |
| Thun, MJ | 1 |
| Logroscino, G | 1 |
| García Rodríguez, LA | 1 |
| Meagher, LJ | 1 |
| McKay, D | 1 |
| Herkes, GK | 1 |
| Needham, M | 1 |
| Roos, RA | 1 |
| Steenvoorden, JM | 1 |
| Mulder, GJ | 1 |
| Van Kempen, GM | 1 |
| Hatori, K | 1 |
| Kondo, T | 1 |
| Mizuno, Y | 1 |
| Casper, D | 1 |
| Yaparpalvi, U | 1 |
| Rempel, N | 1 |
| Werner, P | 1 |
| Robertson, DR | 1 |
| Higginson, I | 1 |
| Macklin, BS | 1 |
| Renwick, AG | 1 |
| Waller, DG | 1 |
| George, CF | 1 |
| Heafield, MT | 2 |
| Sturman, S | 1 |
| Green, M | 1 |
| Factor, SA | 1 |
| Weiner, WJ | 1 |
| Hefti, F | 1 |
| Kalow, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Parkinson's, Genes and Environment (PAGE) Study[NCT00367900] | 3,100 participants (Actual) | Observational | 2006-08-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for acetaminophen and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Use of ibuprofen and risk of Parkinson disease.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Confidence Interv | 2011 |
Ethnic differences in reactions to drugs and xenobiotics. Conjugation reactions.
Topics: Acetaminophen; Amobarbital; Asian People; Canada; Catechol O-Methyltransferase; Ethnicity; Female; G | 1986 |
2 trials available for acetaminophen and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
[Levodopa loading test as an early marker of Parkinson's disease].
Topics: Acetaminophen; Aged; Biomarkers; Gastric Emptying; Humans; Intestinal Absorption; Levodopa; Middle A | 1997 |
The influence of protein containing meals on the pharmacokinetics of levodopa in healthy volunteers.
Topics: Acetaminophen; Adult; Dietary Proteins; Gastric Emptying; Humans; Intestinal Absorption; Levodopa; M | 1991 |
12 other studies available for acetaminophen and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease.
Topics: Acetaminophen; Adolescent; Adult; Benzoquinones; Circulating MicroRNA; Crystallography, X-Ray; Cytoc | 2019 |
Acetaminophen attenuates dopamine neuron degeneration in animal models of Parkinson's disease.
Topics: Acetaminophen; Adrenergic Agents; alpha-Synuclein; Analgesics, Non-Narcotic; Animals; Animals, Genet | 2008 |
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2003 |
An investigation into the inter-relationships of sulphur xeno-biotransformation pathways in Parkinson's and motor neurone diseases.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Biotransformation; Carbocysteine; Erythrocytes; Femal | 2003 |
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cohort Studies; Female; Human | 2005 |
Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antiparkinson Agents; Aspirin; Case-Co | 2006 |
Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.
Topics: Acetaminophen; Acyclovir; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Ba | 2006 |
Acetaminophen sulfation in patients with Parkinson's disease or Huntington's disease is not impaired.
Topics: Acetaminophen; Adult; Aged; Blood Platelets; Chromatography, High Pressure Liquid; Female; Humans; H | 1993 |
Ibuprofen protects dopaminergic neurons against glutamate toxicity in vitro.
Topics: Acetaminophen; Animals; Aspirin; Cell Count; Cells, Cultured; Dopamine; Fetus; Glutamic Acid; Ibupro | 2000 |
Metabolism of low-dose paracetamol in patients with chronic neurological disease.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Ag | 1990 |
Xenobiotic metabolism in Parkinson's disease.
Topics: Acetaminophen; Humans; Parkinson Disease; Reference Values; Sulfates; Sulfoxides; Xenobiotics | 1989 |
Acetaminophen metabolism by cytochrome P450 monooxygenases in Parkinson's disease.
Topics: Acetaminophen; Carbidopa; Cytochrome P-450 Enzyme System; Female; Humans; Levodopa; Male; Middle Age | 1989 |