Page last updated: 2024-10-22

acetaminophen and Hypospadias

acetaminophen has been researched along with Hypospadias in 6 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.

Research Excerpts

ExcerptRelevanceReference
"Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery."9.10Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002)
"Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery."5.10Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002)
"Compared to acetaminophen, mothers reporting NSAIDs were significantly more likely to have offspring with gastroschisis, hypospadias, cleft palate, cleft lip with cleft palate, cleft lip without cleft palate, anencephaly, spina bifida, hypoplastic left heart syndrome, pulmonary valve stenosis, and tetralogy of Fallot (aOR range, 1."3.85Risk comparison for prenatal use of analgesics and selected birth defects, National Birth Defects Prevention Study 1997-2011. ( Ailes, EC; Anderka, M; Broussard, CS; Feldkamp, ML; Gilboa, SM; Interrante, JD; Lind, JN; Taylor, LG; Trinidad, J; Werler, MM, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Zafeiri, A1
Raja, EA1
Mitchell, RT1
Hay, DC1
Bhattacharya, S1
Fowler, PA1
Interrante, JD1
Ailes, EC1
Lind, JN1
Anderka, M1
Feldkamp, ML1
Werler, MM1
Taylor, LG1
Trinidad, J1
Gilboa, SM1
Broussard, CS1
Kundra, P1
Yuvaraj, K1
Agrawal, K1
Krishnappa, S1
Kumar, LT1
Abdulatif, M1
El-Sanabary, M1
Batra, YK1
Arya, VK1
Mahajan, R1
Chari, P1
Ozyuvaci, E1
Altan, A1
Yucel, M1
Yenmez, K1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Analgesic Efficacy of Sacral erectOR Spinae Plane Block and Caudal Block in Patients Undergoing Hypospadias Surgery[NCT05632536]68 participants (Actual)Interventional2022-12-21Completed
Caudal Epidural Block and Ultrasound-guided Dorsal Penile Nerve Block With the In-plane Technique for Pediatric Distal Hypospadias Surgery: A Prospective Observational Study[NCT04215874]26 participants (Actual)Observational2019-04-14Completed
Effect of Intravenous Paracetamol in Combination With Caudal Ropivacaine on Quality of Postoperative Recovery in Paediatric Patients Undergoing Hypospadias Repair[NCT03781505]Phase 464 participants (Anticipated)Interventional2019-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for acetaminophen and Hypospadias

ArticleYear
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C

2012
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C

2012
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C

2012
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C

2012
Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; D

2002
Dose response study of caudal neostigmine for postoperative analgesia in paediatric patients undergoing genitourinary surgery.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Caudal; Child; Child, Preschool; Cholinesterase

2003
Evaluation of adding preoperative or postoperative rectal paracetamol to caudal bupivacaine for postoperative analgesia in children.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:8

    Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anesthetics, Lo

2004

Other Studies

2 other studies available for acetaminophen and Hypospadias

ArticleYear
Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: cohort study of 151 141 singleton pregnancies.
    BMJ open, 2022, 05-03, Volume: 12, Issue:5

    Topics: Acetaminophen; Analgesics; Birth Weight; Cohort Studies; Female; Humans; Hypospadias; Infant, Newbor

2022
Risk comparison for prenatal use of analgesics and selected birth defects, National Birth Defects Prevention Study 1997-2011.
    Annals of epidemiology, 2017, Volume: 27, Issue:10

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics,

2017