acetaminophen has been researched along with Hypertriglyceridemia in 6 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Hypertriglyceridemia: A condition of elevated levels of TRIGLYCERIDES in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This paper reviews the reported data related to the effects of diabetes and hypertriglyceridemia, common lifestyle-related diseases in a modern society, on acetaminophen (APAP)-induced hepatotoxicity and nephrotoxicity in rats and mice." | 8.85 | Diabetes and hypertriglyceridemia modify the mode of acetaminophen-induced hepatotoxicity and nephrotoxicity in rats and mice. ( Doi, K; Ishida, K, 2009) |
| " This paper reviews the reported data related to the effects of diabetes and hypertriglyceridemia, common lifestyle-related diseases in a modern society, on acetaminophen (APAP)-induced hepatotoxicity and nephrotoxicity in rats and mice." | 4.85 | Diabetes and hypertriglyceridemia modify the mode of acetaminophen-induced hepatotoxicity and nephrotoxicity in rats and mice. ( Doi, K; Ishida, K, 2009) |
| " Fischer-344 rats, which are susceptible to APAP nephrotoxicity, have two toxic metabolic pathways involving cytochrome P450-dependent oxidation of APAP to N-acetyl-p-benzoquinone imine (NAPQI) and P450-independent deacetylation of APAP to p-aminophenol (PAP)." | 1.30 | Enhanced nephrotoxicity of acetaminophen in fructose-induced hypertriglyceridemic rats: contribution of oxidation and deacetylation of acetaminophen to an enhancement of nephrotoxicity. ( Doi, K; Ikegami, H; Ishida, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doi, K | 6 |
| Ishida, K | 6 |
| Hanada, T | 1 |
| Sakai, T | 3 |
| Sakazume, M | 3 |
| Hirai, N | 2 |
| Ikegami, H | 4 |
| Watanabe, M | 1 |
1 review available for acetaminophen and Hypertriglyceridemia
| Article | Year |
|---|---|
Diabetes and hypertriglyceridemia modify the mode of acetaminophen-induced hepatotoxicity and nephrotoxicity in rats and mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Diabetes M | 2009 |
5 other studies available for acetaminophen and Hypertriglyceridemia
| Article | Year |
|---|---|
Effects of fructose-induced hypertriglyceridemia on hepatorenal toxicity of acetaminophen in rats.
Topics: Acetaminophen; Animals; Fructose; Hypertriglyceridemia; Kidney; Liver; Male; Rats; Rats, Sprague-Daw | 1995 |
Effects of fructose-induced hypertriglyceridemia on hepatorenal toxicity of acetaminophen in rats. II. Role of enhancement of fructose metabolism and overproduction of triglyceride in the liver and kidney on hepatorenal toxicity of acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Blood Chemical Analysis; Fructose; Glucose; Hypert | 1997 |
Effects of fructose-induced hypertriglyceridemia on hepatorenal toxicity of acetaminophen in rats: role of pharmacokinetics and metabolism of acetaminophen.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dose | 1997 |
Enhanced nephrotoxicity of acetaminophen in fructose-induced hypertriglyceridemic rats: contribution of oxidation and deacetylation of acetaminophen to an enhancement of nephrotoxicity.
Topics: Acetaminophen; Acetylation; Animals; Drug Synergism; Fructose; Hypertriglyceridemia; Inactivation, M | 1997 |
Enhanced nephrotoxicity of acetaminophen in fructose-induced hypertriglyceridemic rats: effect of partial hepatectomy.
Topics: Acetaminophen; Animals; Drug Synergism; Fructose; Hepatectomy; Hypertriglyceridemia; Kidney; Male; O | 1997 |