Page last updated: 2024-10-22

acetaminophen and Hives

acetaminophen has been researched along with Hives in 42 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"To classify patients with a history of aspirin-induced urticaria as cross-reactors or single-drug reactors by oral challenges with another strong COX-1 inhibitor, namely, ketoprofen."9.12Use of ketoprofen oral challenges to detect cross-reactors among patients with a history of aspirin-induced urticaria. ( Asero, R, 2006)
"One hundred and thirty-seven patients with nimesulide-induced urticaria were submitted to a single-blind, placebo-controlled peroral challenge with increasing doses of benzydamine."9.10Benzydamine: an alternative nonsteroidal anti-inflammatory drug in patients with nimesulide-induced urticaria. ( Di Paola, R; Ferrannini, A; Napoli, G; Nettis, E; Tursi, A, 2002)
"To assess the tolerance to both acetaminophen (paracetamol) and aspirin in patients with a history of urticaria induced by nimesulide."9.08Aspirin and paracetamol tolerance in patients with nimesulide-induced urticaria. ( Asero, R, 1998)
"An acute anaphylactic reaction after a conventional antipyretic dose of ibuprofen was diagnosed in a child with allergic rhinitis, recurrent idiopathic urticaria, and nonimmunologic cross-reactive hypersensitivity to nonsteroidal antiinflammatory drugs and acetaminophen."7.74Severe anaphylactic reaction to ibuprofen in a child with recurrent urticaria. ( Chin, CW; Chong, NK; Hoon, LS; Hwee, CY; Kang, LW; Kidon, MI, 2007)
"To classify patients with a history of aspirin-induced urticaria as cross-reactors or single-drug reactors by oral challenges with another strong COX-1 inhibitor, namely, ketoprofen."5.12Use of ketoprofen oral challenges to detect cross-reactors among patients with a history of aspirin-induced urticaria. ( Asero, R, 2006)
"Evaluate aspirin challenge as a means to distinguish single from multiple NSAID intolerance in patients with a clinical history of acute urticaria induced by a single NSAID."5.11Oral aspirin challenges in patients with a history of intolerance to single non-steroidal anti-inflammatory drugs. ( Asero, R, 2005)
"One hundred and thirty-seven patients with nimesulide-induced urticaria were submitted to a single-blind, placebo-controlled peroral challenge with increasing doses of benzydamine."5.10Benzydamine: an alternative nonsteroidal anti-inflammatory drug in patients with nimesulide-induced urticaria. ( Di Paola, R; Ferrannini, A; Napoli, G; Nettis, E; Tursi, A, 2002)
"Previous studies show skin reactions after exposure to acetaminophen and/or nimesulide to occur in about 10% of patients with a history of urticaria induced by aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs)."5.09Risk factors for acetaminophen and nimesulide intolerance in patients with NSAID-induced skin disorders. ( Asero, R, 1999)
"To assess the tolerance to both acetaminophen (paracetamol) and aspirin in patients with a history of urticaria induced by nimesulide."5.08Aspirin and paracetamol tolerance in patients with nimesulide-induced urticaria. ( Asero, R, 1998)
"Relevant articles in the medical literature were derived from searching the MEDLINE database with key terms aspirin-sensitive asthma, cyclo-oxygenase enzymes 1 and 2."4.81Sensitivity to nonsteroidal anti-inflammatory drugs. ( Namazy, JA; Simon, RA, 2002)
"An acute anaphylactic reaction after a conventional antipyretic dose of ibuprofen was diagnosed in a child with allergic rhinitis, recurrent idiopathic urticaria, and nonimmunologic cross-reactive hypersensitivity to nonsteroidal antiinflammatory drugs and acetaminophen."3.74Severe anaphylactic reaction to ibuprofen in a child with recurrent urticaria. ( Chin, CW; Chong, NK; Hoon, LS; Hwee, CY; Kang, LW; Kidon, MI, 2007)
" Oral rechallenge resulted in generalized urticaria associated with an increased plasma level of histamine."3.71Acetaminophen (paracetamol)-induced anaphylactic shock. ( Bachmeyer, C; Blay, F; Habki, R; Leynadier, F; Vermeulen, C, 2002)
"We describe four cases of anaphylaxis to paracetamol without co-existing aspirin intolerance and review the Australian experience in paracetamol anaphylaxis."3.68Paracetamol anaphylaxis. ( Czarny, D; Leung, R; Plomley, R, 1992)
"Ibuprofen was the most commonly implicated drug, followed by acetylsalicylic acid (ASA)."2.76Response to a selective COX-2 inhibitor in patients with urticaria/angioedema induced by nonsteroidal anti-inflammatory drugs. ( Blanca, M; Blanca-López, N; Campo, P; Canto, G; Doña, I; Fernández, J; Gómez, AI; Jagemann, LR; Laguna, JJ; Rondón, C; Rosado, A; Torres, MJ, 2011)
"Ibuprofen was the most frequent cause of reactions (35%), however, diclofenac was the most frequent cause of anaphylaxis (48%)."1.38Oral drug challenges in non-steroidal anti-inflammatory drug-induced urticaria, angioedema and anaphylaxis. ( Chaudhry, T; Heddle, R; Hissaria, P; Kette, F; Smith, WB; Wiese, M, 2012)
"We report a case of toxic epidermal necrolysis-type drug eruption."1.31A case of toxic epidermal necrolysis-type drug eruption induced by oral lysozyme chloride. ( Asahi, M; Kobayashi, M; Yamamoto, O; Yasuda, H, 2000)
"Nimesulide was tolerated by 115/122 (94."1.30Long-term tolerability of nimesulide and acetaminophen in nonsteroidal antiinflammatory drug-intolerant patients. ( D'Ambrosio, FP; Di Fonso, M; Giuffreda, F; Papa, G; Quaratino, D; Romano, A; Venuti, A, 1997)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.90)18.7374
1990's9 (21.43)18.2507
2000's17 (40.48)29.6817
2010's7 (16.67)24.3611
2020's4 (9.52)2.80

Authors

AuthorsStudies
Jeand'heur, A1
Pelletier, F1
Girardin, P1
Moumane, L1
Aubin, F1
Castelain, F1
Topal, OY1
Ilknur, KC1
Irem, YT1
Muge, T1
Ersoy, C1
Betul, K1
Emine, DM1
Liu, JB1
Hao, D1
Veraldi, S1
Romagnuolo, M1
Benzecry, V1
Rodríguez-Fernández, A1
Sánchez-Domínguez, M1
Noguerado-Mellado, B1
Rojas-Pérez-Ezquerra, P1
Asero, R6
Barbarroja-Escudero, J1
Sanchez-Gonzalez, MJ1
Rodriguez-Rodriguez, M1
Antolin-Amerigo, D1
Vélez, D1
Medina-Exposito, I1
Sanchez-Gomez-Aparici, E1
Piteiro, AB1
Alvarez-Mon, M1
Dass, K1
Bose, S1
Ditto, AM1
Doña, I1
Blanca-López, N1
Jagemann, LR1
Torres, MJ1
Rondón, C1
Campo, P1
Gómez, AI1
Fernández, J1
Laguna, JJ1
Rosado, A1
Blanca, M1
Canto, G1
Chaudhry, T1
Hissaria, P1
Wiese, M1
Heddle, R1
Kette, F1
Smith, WB1
Takeo, N1
Hatano, Y1
Yamamoto, K1
Shiota, S1
Fujiwara, S1
Bachmeyer, C1
Vermeulen, C1
Habki, R1
Blay, F1
Leynadier, F1
Namazy, JA1
Simon, RA1
Wojas-Pelc, A1
Setkowicz, M1
Kiełtyka, A1
Bogdaszewska-Czabanowska, J1
Rodríguez, M1
Enrique, E1
Castello, JV1
de Mateo, JA1
Roca, B1
Malek, T1
Morgan, S1
Dorman, S1
Gamboa, P1
Sanz, ML1
Caballero, MR1
Urrutia, I1
Antépara, I1
Esparza, R1
de Weck, AL1
Kidon, MI2
Kang, LW2
Chin, CW2
Hoon, LS2
See, Y1
Goh, A1
Lin, JT1
Chay, OM1
Iancovici Kidon, M1
Abramovitch, I1
Steinberg, S1
Barash, J1
Tsujino, Y1
Okamoto, N1
Morita, E1
Bergendorff, O1
Hansson, C1
Hwee, CY1
Chong, NK1
Bateman, DN1
Woodhouse, KW1
Rawlins, MD1
Ownby, DR1
Sabbah, A1
Sainte-Laudy, J1
Drouet, M1
Lauret, MG1
Loiry, M1
Quaratino, D1
Romano, A1
Papa, G1
Di Fonso, M1
Giuffreda, F1
D'Ambrosio, FP1
Venuti, A1
Kosnik, M1
Music, E1
Matjaz, F1
Suskovic, S1
Samanta, BB1
Kobayashi, M1
Yamamoto, O1
Yasuda, H1
Asahi, M1
Nettis, E2
Marcandrea, M1
Ferrannini, A2
Tursi, A2
Di Paola, R1
Napoli, G1
Juhlin, L1
Michelson, PA1
Leung, R1
Plomley, R1
Czarny, D1
Goodman, DL1
McDonnell, JT1
Nelson, HS1
Vaughan, TR1
Weber, RW1
Pastorello, E1
Qualizza, RM1
Luraghi, MT1
Ispano, M1
Villa, AM1
Ortolani, C1
Zanussi, C1
Cole, TO1

Reviews

1 review available for acetaminophen and Hives

ArticleYear
Sensitivity to nonsteroidal anti-inflammatory drugs.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 89, Issue:6

    Topics: Acetaminophen; Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bleedin

2002

Trials

9 trials available for acetaminophen and Hives

ArticleYear
Response to a selective COX-2 inhibitor in patients with urticaria/angioedema induced by nonsteroidal anti-inflammatory drugs.
    Allergy, 2011, Volume: 66, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cycl

2011
Oral aspirin challenges in patients with a history of intolerance to single non-steroidal anti-inflammatory drugs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anal

2005
Use of ketoprofen oral challenges to detect cross-reactors among patients with a history of aspirin-induced urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroida

2006
Etoricoxib challenge in patients with chronic urticaria with NSAID intolerance.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:6

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cyclooxygenase

2007
Aspirin and paracetamol tolerance in patients with nimesulide-induced urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 81, Issue:3

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibit

1998
Risk factors for acetaminophen and nimesulide intolerance in patients with NSAID-induced skin disorders.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 82, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Bacterial

1999
Tolerability of nimesulide and paracetamol in patients with NSAID-induced urticaria/angioedema.
    Immunopharmacology and immunotoxicology, 2001, Volume: 23, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Angioedema; Anti-Inflammatory Agents, Non

2001
Benzydamine: an alternative nonsteroidal anti-inflammatory drug in patients with nimesulide-induced urticaria.
    Allergy, 2002, Volume: 57, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzydamin

2002
Chronic urticaria exacerbated by the antioxidant food preservatives, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Acetaminophen; Adult; Antioxidants; Aspirin; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Chr

1990

Other Studies

32 other studies available for acetaminophen and Hives

ArticleYear
A case of immediate hypersensitivity reaction after an oral administration of patent blue dye.
    Contact dermatitis, 2020, Volume: 82, Issue:2

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Breast Neoplas

2020
Negative predictive value of provocation tests for nonsteroidal anti-inflammatory drugs in children.
    Allergy and asthma proceedings, 2020, 07-01, Volume: 41, Issue:4

    Topics: Acetaminophen; Administration, Oral; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Child; Chi

2020
[Acetaminophen induced delayed-type urticaria and angioedema in a child].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2020, Aug-02, Volume: 58, Issue:8

    Topics: Acetaminophen; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Fever; Humans; Infant; Urticaria

2020
Urticaria as a first clinical manifestation of COVID-19.
    European journal of dermatology : EJD, 2020, Dec-01, Volume: 30, Issue:6

    Topics: Acetaminophen; Adult; Antiviral Agents; Cetirizine; COVID-19; COVID-19 Drug Treatment; Dermatologic

2020
Flare-Up Phenomenon of Intradermal Test with Anaphylactic Reaction to Paracetamol (Acetaminophen).
    Recent patents on inflammation & allergy drug discovery, 2019, Volume: 13, Issue:1

    Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Aged, 80 and over; Allergens; Anap

2019
Multiple nonsteroidal anti-inflammatory drug-induced cutaneous disease: what differentiates patients with and without underlying chronic spontaneous urticaria?
    International archives of allergy and immunology, 2014, Volume: 163, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroida

2014
Fixed drug urticaria: a report of two patients.
    Allergology international : official journal of the Japanese Society of Allergology, 2015, Volume: 64, Issue:1

    Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Drug Hype

2015
An unusual case of immediate hypersensitivity reaction to a common medication.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2016, Volume: 117, Issue:1

    Topics: Acetaminophen; Administration, Oral; Adult; Anaphylaxis; Desensitization, Immunologic; Drug Hypersen

2016
Oral drug challenges in non-steroidal anti-inflammatory drug-induced urticaria, angioedema and anaphylaxis.
    Internal medicine journal, 2012, Volume: 42, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Stero

2012
Case of Mycoplasma pneumoniae infection with maculopapular-type eruptions due to acetaminophen.
    The Journal of dermatology, 2013, Volume: 40, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Asian People; Drug Eruptions;

2013
Acetaminophen (paracetamol)-induced anaphylactic shock.
    Southern medical journal, 2002, Volume: 95, Issue:7

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anaphylaxis; Epinephrine; Female; Histamine; Humans;

2002
[Cutaneous changes occurring after taking non-steroidal anti-inflammatory drugs--five-years' retrospective studies].
    Przeglad lekarski, 2002, Volume: 59, Issue:12

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyrone; Drug Eruptions; Er

2002
Tolerability of cyclooxygenase 2 inhibitors and the advisability of oral challenge.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 91, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib;

2003
Paracetamol (acetaminophen) allergy.
    Journal of pain and symptom management, 2004, Volume: 27, Issue:2

    Topics: Acetaminophen; Angioedema; Diagnosis, Differential; Drug Hypersensitivity; Humans; Male; Middle Aged

2004
The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndrome.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:9

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Basophil Degra

2004
Early presentation with angioedema and urticaria in cross-reactive hypersensitivity to nonsteroidal antiinflammatory drugs among young, Asian, atopic children.
    Pediatrics, 2005, Volume: 116, Issue:5

    Topics: Acetaminophen; Administration, Oral; Adolescent; Allergens; Angioedema; Anti-Inflammatory Agents, No

2005
Cross-reactive hypersensitivity to COX inhibitors in a child with mild allergic rhinitis.
    The Israel Medical Association journal : IMAJ, 2005, Volume: 7, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Child;

2005
Acetaminophen-induced urticaria without aspirin intolerance.
    The Journal of dermatology, 2007, Volume: 34, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dr

2007
Urticaria and anaphylaxis to povidone in a paracetamol preparation.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anaphylaxis; Child; Drug Eruptions; Humans; Male; Pharmaceu

2007
Severe anaphylactic reaction to ibuprofen in a child with recurrent urticaria.
    Pediatrics, 2007, Volume: 120, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Child

2007
Adverse reactions to N-acetylcysteine.
    Human toxicology, 1984, Volume: 3, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Edetic Acid; Female; Humans; Male; Skin Test

1984
Acetaminophen-induced urticaria and tolerance of ibuprofen in an eight-year-old child.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:1 Pt 1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Drug Hypers

1997
[Anaphylactic or anaphylactoid reactions to paracetamol. Report of 3 cases].
    Allergie et immunologie, 1997, Volume: 29, Issue:3

    Topics: Acetaminophen; Adult; Anaphylaxis; Basophil Degranulation Test; CD4-Positive T-Lymphocytes; Drug Eru

1997
Long-term tolerability of nimesulide and acetaminophen in nonsteroidal antiinflammatory drug-intolerant patients.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997, Volume: 79, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Angioedema; Ant

1997
Relative safety of meloxicam in NSAID-intolerant patients.
    Allergy, 1998, Volume: 53, Issue:12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Angioedema; Anti-Inflammatory Agents, Non-Steroidal;

1998
Paracetamol induced urticaria.
    The Journal of the Association of Physicians of India, 1999, Volume: 47, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Middle Aged; Urticaria

1999
A case of toxic epidermal necrolysis-type drug eruption induced by oral lysozyme chloride.
    The Journal of dermatology, 2000, Volume: 27, Issue:6

    Topics: Acetaminophen; Administration, Oral; Adult; Anti-Inflammatory Agents; Betamethasone; Biopsy, Needle;

2000
Recurrent urticaria.
    International journal of dermatology, 1976, Volume: 15, Issue:4

    Topics: Acetaminophen; Histamine H1 Antagonists; Humans; Recurrence; Urticaria

1976
Letter: Rash, weakness, and acetaminophen.
    Annals of internal medicine, 1975, Volume: 83, Issue:3

    Topics: Acetaminophen; Drug Hypersensitivity; Humans; Male; Middle Aged; Urticaria

1975
Paracetamol anaphylaxis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:9

    Topics: Acetaminophen; Anaphylaxis; Angioedema; Aspirin; Bronchial Spasm; Cross Reactions; Humans; Hypotensi

1992
[Occurrence of drug reactions].
    Bollettino dell'Istituto sieroterapico milanese, 1986, Volume: 65, Issue:1

    Topics: Acetaminophen; Adult; Anaphylaxis; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Emergencies;

1986
Urticaria from paracetamol.
    Clinical and experimental dermatology, 1985, Volume: 10, Issue:4

    Topics: Acetaminophen; Humans; Urticaria

1985