acetaminophen has been researched along with Hip Fractures in 19 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The inclusion of IV acetaminophen as part of a multimodal pain regimen led to fewer episodes of delirium in this study." | 7.96 | Delirium Reduced With Intravenous Acetaminophen in Geriatric Hip Fracture Patients. ( Connolly, KP; Kleinman, RS; Mehta, SN; Neuman, MD; Stevenson, KL, 2020) |
| "The aim of this study was to determine whether the administration of liposomal bupivacaine decreased opioid use and delirium in patients sustaining a hip fracture." | 4.31 | Liposomal Bupivacaine Decreases Intravenous Opioid Use in Patients with Hip Fracture: A Modification to a Novel Pain Protocol. ( Donegan, D; Fryhofer, GW; Looby, S; Mehta, S; Stein, MK; Stevenson, KL, 2023) |
| "The inclusion of IV acetaminophen as part of a multimodal pain regimen led to fewer episodes of delirium in this study." | 3.96 | Delirium Reduced With Intravenous Acetaminophen in Geriatric Hip Fracture Patients. ( Connolly, KP; Kleinman, RS; Mehta, SN; Neuman, MD; Stevenson, KL, 2020) |
| "FICB improved postoperative pain on movement compared with intravenous acetaminophen without increasing the complication rate." | 2.90 | Comparison of the postoperative analgesic efficacies of intravenous acetaminophen and fascia iliaca compartment block in hip fracture surgery: A randomised controlled trial. ( Dan'ura, T; Matsui, Y; Nishiyama, A; Noda, T; Ozaki, T; Sakura, S; Yamamoto, N, 2019) |
| " Intravenous (iv) acetaminophen has been reported to have superior efficacy and bioavailability than oral acetaminophen." | 2.82 | Effect of intravenous acetaminophen on postoperative outcomes in hip fracture patients: a systematic review and narrative synthesis. ( Cho, JSH; Clarke, H; Engelsakis, M; Jacob, B; Karkouti, K; McCarthy, K; McCluskey, S; Schiavo, S; Wong, J; Zywiel, M, 2022) |
| "The choice of IV or other analgesics in treating hip fractures affects analgesic usage, side effects, medical costs, and patient outcomes." | 1.91 | Outcomes of hip fracture treatment with intravenous morphine and with other analgesics: postoperative analgesic medical expense, severity of pain and hospitalisation-a retrospective study. ( Nimkingratana, P; Phinyo, P; Srichan, R; Tanasombatkul, K, 2023) |
| "To assess whether a "drugome-wide" screen with case-crossover design is a feasible approach for identifying candidate drugs and drug-drug interactions." | 1.46 | Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease. ( Hartikainen, S; Koponen, M; Lavikainen, P; Paananen, J; Taipale, H; Tanskanen, A; Tiihonen, J; Tolppanen, AM, 2017) |
| "Nurses play a pivotal role in treating postoperative pain in patients with dementia and monitoring the effects of administered analgesics." | 1.40 | Analgesics in postoperative care in hip fracture patients with dementia - reported by nurses. ( Hartikainen, S; Kankkunen, P; Kvist, T; Rantala, M, 2014) |
| "We compared an approach using scheduled analgesic dosing with as-needed analgesic dosing in patients after hip fracture surgery, to compare these approaches in terms of (1) resting and dynamic pain intensity, (2) postoperative patient mobility, and (3) functional end points." | 1.39 | Scheduled analgesic regimen improves rehabilitation after hip fracture surgery. ( Cheung, LP; Chin, RP; Ho, CH, 2013) |
| " Paracetamol (acetaminophen in North America) has better bioavailability when given intravenously than orally and has been successfully used in the postoperative care of orthopedic patients." | 1.39 | Can intravenous paracetamol reduce opioid use in preoperative hip fracture patients? ( Mackenney, P; Page, J; Tsang, KS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (63.16) | 24.3611 |
| 2020's | 6 (31.58) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, J | 1 |
| Wang, T | 1 |
| Zheng, X | 1 |
| Long, Y | 1 |
| Wang, X | 1 |
| Zhang, Q | 1 |
| Liu, J | 2 |
| Zhang, G | 1 |
| Zha, J | 1 |
| Hou, Z | 1 |
| Zhang, Y | 1 |
| Cho, JSH | 1 |
| McCarthy, K | 1 |
| Schiavo, S | 1 |
| Jacob, B | 1 |
| Engelsakis, M | 1 |
| Zywiel, M | 1 |
| Karkouti, K | 1 |
| McCluskey, S | 1 |
| Clarke, H | 1 |
| Wong, J | 2 |
| Stone, AB | 1 |
| Iban, YC | 1 |
| Zhong, H | 1 |
| Poeran, J | 1 |
| Cozowicz, C | 1 |
| Illescas, A | 1 |
| Memtsoudis, SG | 1 |
| Stevenson, KL | 2 |
| Stein, MK | 1 |
| Fryhofer, GW | 1 |
| Looby, S | 1 |
| Donegan, D | 1 |
| Mehta, S | 1 |
| Srichan, R | 1 |
| Phinyo, P | 1 |
| Tanasombatkul, K | 1 |
| Nimkingratana, P | 1 |
| Connolly, KP | 1 |
| Kleinman, RS | 1 |
| Neuman, MD | 1 |
| Mehta, SN | 1 |
| Tolppanen, AM | 1 |
| Taipale, H | 1 |
| Koponen, M | 1 |
| Tanskanen, A | 1 |
| Lavikainen, P | 1 |
| Paananen, J | 1 |
| Tiihonen, J | 1 |
| Hartikainen, S | 2 |
| Casey, SD | 1 |
| Stevenson, DE | 1 |
| Mumma, BE | 1 |
| Slee, C | 1 |
| Wolinsky, PR | 1 |
| Hirsch, CH | 1 |
| Tyler, K | 1 |
| Yamamoto, N | 1 |
| Sakura, S | 1 |
| Noda, T | 1 |
| Nishiyama, A | 1 |
| Dan'ura, T | 1 |
| Matsui, Y | 1 |
| Ozaki, T | 1 |
| Chin, RP | 1 |
| Ho, CH | 1 |
| Cheung, LP | 1 |
| Rantala, M | 1 |
| Kvist, T | 1 |
| Kankkunen, P | 1 |
| Di Filippo, A | 1 |
| Magherini, M | 1 |
| Ruggiano, P | 1 |
| Ciardullo, A | 1 |
| Falsini, S | 1 |
| Jensen-Dahm, C | 1 |
| Palm, H | 1 |
| Gasse, C | 1 |
| Dahl, JB | 1 |
| Waldemar, G | 1 |
| Sanzone, AG | 1 |
| Chuang, PY | 1 |
| Shen, SH | 1 |
| Yang, TY | 1 |
| Huang, TW | 1 |
| Huang, KC | 1 |
| Hellström, PM | 1 |
| Samuelsson, B | 1 |
| Al-Ani, AN | 1 |
| Hedström, M | 1 |
| Björkelund, KB | 1 |
| Hommel, A | 1 |
| Thorngren, KG | 1 |
| Gustafson, L | 1 |
| Larsson, S | 1 |
| Lundberg, D | 1 |
| Tsang, KS | 1 |
| Page, J | 1 |
| Mackenney, P | 1 |
| Feldt, KS | 1 |
| Ryden, MB | 1 |
| Miles, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?[NCT05025228] | 170 participants (Actual) | Observational | 2019-06-01 | Completed | |||
| Gastric Emptying Time of a Carbohydrate-rich Drink in Elderly Patients With Acute Hip Fracture: a Pilot Study[NCT02753010] | 30 participants (Actual) | Observational | 2011-03-31 | Completed | |||
| Impact of Intrathecal Dexamethasone Administration for Elderly Patients With Proximal Femoral Fracture[NCT03856502] | 60 participants (Actual) | Interventional | 2012-11-11 | Completed | |||
| Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control: A Blinded Randomized Placebo-Controlled Trial[NCT02694653] | Phase 1 | 200 participants (Anticipated) | Interventional | 2014-10-31 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for acetaminophen and Hip Fractures
| Article | Year |
|---|---|
Effect of intravenous acetaminophen on postoperative outcomes in hip fracture patients: a systematic review and narrative synthesis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Hip Fractures; Humans; Pain, Post | 2022 |
Use of Nonopioid Analgesics and the Impact on Patient Outcomes.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2016 |
2 trials available for acetaminophen and Hip Fractures
| Article | Year |
|---|---|
Comparison of the postoperative analgesic efficacies of intravenous acetaminophen and fascia iliaca compartment block in hip fracture surgery: A randomised controlled trial.
Topics: Acetaminophen; Aged, 80 and over; Analgesics; Arthroplasty, Replacement, Hip; Fascia; Female; Femora | 2019 |
Normal gastric emptying time of a carbohydrate-rich drink in elderly patients with acute hip fracture: a pilot study.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; | 2017 |
15 other studies available for acetaminophen and Hip Fractures
| Article | Year |
|---|---|
Use of Intravenous Paracetamol Preoperatively Favors Lower Risk of Delirium and Functional Recovery in Elderly Patients with Hip Fracture: A Propensity Score-Matched Analysis.
Topics: Acetaminophen; Aged; Delirium; Hip Fractures; Humans; Pain; Propensity Score; Retrospective Studies | 2022 |
Opioid sparing effects of intravenous and oral acetaminophen in hip fracture patients: A population-based study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Hip Fractu | 2023 |
Liposomal Bupivacaine Decreases Intravenous Opioid Use in Patients with Hip Fracture: A Modification to a Novel Pain Protocol.
Topics: Acetaminophen; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Delirium; Hip | 2023 |
Outcomes of hip fracture treatment with intravenous morphine and with other analgesics: postoperative analgesic medical expense, severity of pain and hospitalisation-a retrospective study.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2023 |
Delirium Reduced With Intravenous Acetaminophen in Geriatric Hip Fracture Patients.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Delirium; Female; Hip Fractures; Humans; | 2020 |
Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Codeine; Cross-Over Studies; Drug | 2017 |
Emergency Department Pain Management Following Implementation of a Geriatric Hip Fracture Program.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Cr | 2017 |
Scheduled analgesic regimen improves rehabilitation after hip fracture surgery.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Biomechanical | 2013 |
Analgesics in postoperative care in hip fracture patients with dementia - reported by nurses.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Attitude of Health Pe | 2014 |
Postoperative analgesia in patients older than 75 years undergoing intervention for per-trochanteric hip fracture: a single centre retrospective cohort study.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Cohort Studies; Drug Administration Routes; Drug Adminis | 2015 |
Postoperative Treatment of Pain after Hip Fracture in Elderly Patients with Dementia.
Topics: Acetaminophen; Administration, Oral; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Dement | 2016 |
Non-steroidal anti-inflammatory drugs and the risk of a second hip fracture: a propensity-score matching study.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Databases, Factu | 2016 |
Reducing delirium in elderly patients with hip fracture: a multi-factorial intervention study.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Anesthesia, General; Anesthesia, Spinal; Choline | 2010 |
Can intravenous paracetamol reduce opioid use in preoperative hip fracture patients?
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Hip Fr | 2013 |
Treatment of pain in cognitively impaired compared with cognitively intact older patients with hip-fracture.
Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; C | 1998 |