Page last updated: 2024-10-22

acetaminophen and Hepatitis

acetaminophen has been researched along with Hepatitis in 44 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
" There are many underlying etiologies, including acetaminophen toxicity, drug induced liver injury, and hepatitis."5.01Acute liver failure: A review for emergency physicians. ( Koyfman, A; Long, B; Montrief, T, 2019)
" In Europe and North America a large proportion of cases are due to acetaminophen and to idiosyncratic drug reactions, whereas reports from emerging countries in Asia and Africa feature viral illnesses, particularly hepatitis B and E."4.84Etiologies of acute liver failure. ( Lee, WM, 2008)
"The aim of the research was to investigate the hepatoprotective properties of the Maitake mushrooms thick extract in the experiment on rats with paracetamol (acetaminophen)-induced hepatitis."4.02Application of the thick extract from Maitake mushrooms for correction of metabolic disorders under the paracetamol hepatitis in rats. ( Fira, L; Herasymets, I; Medvid, I, 2021)
" To study this, we reviewed serum enzyme patterns early in the course of acute liver injury in patients with acute viral hepatitis A and B (n = 51), ischemic hepatitis (n = 20), and acetaminophen injury (n = 26)."3.69Serum lactic dehydrogenase in the differential diagnosis of acute hepatocellular injury. ( Cassidy, WM; Reynolds, TB, 1994)
"Ultrastructural changes were observed in 23 consecutive patients who died from fulminant hepatic failure due to hepatitis B virus (4 cases), sporadic non-A, non-B (7), or paracetamol (acetaminophen) overdose (12) and in 3 patients with subacute hepatic necrosis of unknown cause."3.67Fulminant hepatitis. An ultrastructural study. ( Fagan, EA; McCaul, TF; Portmann, B; Tovey, G; Williams, R; Zuckerman, AJ, 1986)
"A significant proportion of cases of acute liver failure (ALF) do not have an identifiable cause; so called "non A-E," "non A, non B, non C," "seronegative" or "indeterminate" hepatitis."2.58Systematic review: non A-E, seronegative or indeterminate hepatitis; what is this deadly disease? ( Brennan, PN; Donnelly, MC; Simpson, KJ, 2018)
"Hypoxic hepatitis is a clinical condition precipitated by prolonged periods of oxygen deprivation to the liver."1.46Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis. ( Antoine, DJ; Curry, SC; Jaeschke, H; Jenkins, RE; McGill, MR; Olson, JC; Sharpe, MR; Weemhoff, JL; Woolbright, BL, 2017)
" Alanine aminotransferase at baseline and following paracetamol administration was noted, as well as dosage and duration of paracetamol, along with participants' demographic details."1.46Frequency of worsening liver function in severe dengue hepatitis patients receiving paracetamol: A retrospective analysis of hospital data. ( Aslam, F; Hakeem, H; Nasir, N; Siddiqui, F; Syed, AA, 2017)
"Curcumin was administered for 7 successive days, while paracetamol was administered at day six of treatment."1.40Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats. ( Abdo Nassan, M; Ismail, TA; Soliman, MM, 2014)
"Liver regeneration may be impaired in acute liver failure due to either inhibition of the proliferative response or ongoing liver cell death."1.32Activin A and follistatin in acute liver failure. ( Evans, LW; Hughes, RD, 2003)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199011 (25.00)18.7374
1990's5 (11.36)18.2507
2000's5 (11.36)29.6817
2010's17 (38.64)24.3611
2020's6 (13.64)2.80

Authors

AuthorsStudies
Dissanayake, DMDIB1
Gunaratne, WMSN1
Kumarihamy, KWMPP1
Kularatne, SAM1
Kumarasiri, PVR1
Herasymets, I1
Fira, L1
Medvid, I1
Nawaz, MA3
Aleem, A3
Hussain, SA3
Manzoor, M3
Latif, S3
Sarwar, MI3
Khan, M3
Talib, S3
Zhang, Y2
Biao, Y1
Chu, X1
Hao, L1
Shi, C1
Liu, Y1
Wang, X1
Wang, YQ1
Geng, XP1
Wang, MW1
Wang, HQ1
Zhang, C1
He, X1
Liang, SM1
Xu, DX1
Chen, X1
Yakoob, MY1
Ali, SA1
Brennan, PN1
Donnelly, MC1
Simpson, KJ1
Montrief, T1
Koyfman, A1
Long, B1
Yang, R1
Tonnesseen, TI1
Baali, N1
Mezrag, A1
Bouheroum, M1
Benayache, F1
Benayache, S1
Souad, A1
Werawatganon, D1
Linlawan, S1
Thanapirom, K1
Somanawat, K1
Klaikeaw, N1
Rerknimitr, R1
Siriviriyakul, P1
Ward, J2
Kanchagar, C1
Veksler-Lublinsky, I1
Lee, RC1
McGill, MR2
Jaeschke, H3
Curry, SC2
Ambros, VR1
Soliman, MM1
Abdo Nassan, M1
Ismail, TA1
Woolbright, BL2
Richards, JA1
Bucsaiova, M1
Hesketh, EE1
Ventre, C1
Henderson, NC1
Simpson, K1
Bellamy, CO1
Howie, SE1
Anderton, SM1
Hughes, J1
Wigmore, SJ1
Weemhoff, JL1
Jenkins, RE1
Sharpe, MR1
Olson, JC1
Antoine, DJ1
Syed, AA1
Aslam, F1
Hakeem, H1
Siddiqui, F1
Nasir, N1
Adukauskiene, D1
Dockiene, I1
Naginiene, R1
Kevelaitis, E1
Pundzius, J1
Kupcinskas, L1
Savino, F1
Lupica, MM1
Tarasco, V1
Locatelli, E1
Garazzino, S1
Tovo, PA1
Moniaux, N1
Darnaud, M1
Dos Santos, A1
Jamot, L1
Samuel, D1
Amouyal, P1
Amouyal, G1
Bréchot, C1
Faivre, J1
Bala, S1
Petrasek, J1
Mundkur, S1
Catalano, D1
Levin, I1
Alao, H1
Kodys, K1
Szabo, G1
Kubes, P1
Mehal, WZ1
Hou, HS1
Liao, CL1
Sytwu, HK1
Liao, NS1
Huang, TY1
Hsieh, TY1
Chu, HC1
Hughes, RD1
Evans, LW1
CAREDDU, P1
MEREU, T1
APOLLONIO, T1
EDER, H1
Bernal, W1
Ma, Y1
Smith, HM1
Portmann, B3
Wendon, J1
Vergani, D1
Lee, WM1
Schmid, M1
Cassidy, WM1
Reynolds, TB1
Evans, PJ1
Evans, RW1
Bomford, A1
Williams, R3
Halliwell, B1
Bernard, PH1
Le Bail, B1
Carles, J1
Fawaz, R1
Balabaud, C1
Rosenbaum, J1
Bioulac-Sage, P1
Hift, RJ1
Spearman, CW1
Lemmer, ER1
Kirsch, RE1
Schiff, ER1
Ash, SR1
Caldwell, CA1
Singer, GG1
Lowell, JA1
Howard, TK1
Rustgi, VK1
Gazzard, BG1
Murray-Lyon, IM1
Talbot, IC1
Ackerman, Z1
Flugelman, MY1
Wax, Y1
Shouval, D1
Levy, M1
McCaul, TF1
Fagan, EA1
Tovey, G1
Zuckerman, AJ1
Rueff, B1
Benhamou, JP1
Hammar, CH1
Prellwitz, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2a Study to Evaluate the Safety and Tolerability of OCR-002 (Ornithine Phenylacetate) in the Treatment of Patients With Acute Liver Failure/Severe Acute Liver Injury[NCT01548690]Phase 247 participants (Actual)Interventional2012-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Ammonia

To evaluate the effect of OCR-002 on ammonia levels in patients with acute liver failure/severe acute liver injury (NCT01548690)
Timeframe: Baseline and 72 Hours

InterventionPercent Change (Mean)
Maximum Dose Level 3.33 g/24h41.2
Maximum Dose Level 6.65 g/24h16.6
Maximum Dose Level 10 g/24h41.8
Maximum Dose Level 20g/24h38.4

Measurement of OCR-002 Plasma Concentration

To evaluate the steady state pharmacokinetic and pharmacodynamic profile of OCR-002 in patients with impaired and intact renal function using urinary phenylacetylglutamine (PAGN) as a surrogate marker (NCT01548690)
Timeframe: 24 Hours after last infusion

Interventionmicrograms per millileter (Mean)
Maximum Dose Level 3.33 g/24h65.6
Maximum Dose Level 6.65 g/24h32.2
Maximum Dose Level 10 g/24h33.4
Maximum Dose Level 20g/24h104.9

Neurological Function Measured by the Orientation Log (O-log)

The orientation log focuses on orientation to place, time, and circumstance. There are 10 items on the orientation log, which are scored 0-3. A spontaneous correct response is awarded 3 points. A spontaneous response that is lacking or incorrect, but a correct response is provided following a logical cue is awarded 2 points. A score of 1 is given if spontaneous and cued responses are lacking or incorrect, but a correct response is provided in a recognition format. A score of 0 is given if the spontaneous, cued, or recognition format does not generate a correct answer. Scores from the 10 items are summed and the final score ranges from 0 to 30. (NCT01548690)
Timeframe: 30 Days

Interventionunits on a scale (Mean)
Maximum Dose Level 3.33 g/24h23.8
Maximum Dose Level 6.65 g/24h24.0
Maximum Dose Level 10 g/24h24.0
Maximum Dose Level 20g/24h24.0

Neurological Function Measured by the West Haven Criteria (WHC) for Hepatic Encephalopathy

The West Haven Criteria (WHC) for Hepatic Encephalopathy measures the severity of encephalopathy and patient's level of consciousness. The scale ranges from 0 to 4; a minimum score of 0 represents a better outcome, and a maximum total score of 4 represents a worse outcome. A score of 0 corresponds to normal consciousness and behavior and normal neurological examination. A score of 1 corresponds to mild lack of awareness, shortened attention span, and impaired addition or subtraction; mild asterixis or tremor. A score of 2 corresponds to lethargy, disorientated or inappropriate behavior, obvious asterixis; slurred speech. A score of 3 corresponds to somnolent but arousable, gross disorientation or bizarre behavior, muscle rigidity and clonus; hyperreflexia. A score of 4 corresponds to coma and decerebrate posturing. (NCT01548690)
Timeframe: 120 hours from start of infusion

Interventionunits on a scale (Mean)
Maximum Dose Level 3.33 g/24h2.4
Maximum Dose Level 6.65 g/24h3.2
Maximum Dose Level 10 g/24h1.6
Maximum Dose Level 20g/24h1.8

Number of Participants That do Not Tolerate the Administered Dose and Had Grade 3 or 4 Treatment Emergent Adverse Events as a Measure of Safety and Tolerability

To evaluate the safety and tolerability of OCR-002 in patients with acute liver failure/severe acute liver injury (NCT01548690)
Timeframe: 30 Days

InterventionParticipants (Count of Participants)
Maximum Dose Level 3.33 g/24h0
Maximum Dose Level 6.65 g/24h0
Maximum Dose Level 10 g/24h0
Maximum Dose Level 20g/24h0

Reviews

10 reviews available for acetaminophen and Hepatitis

ArticleYear
Systematic review: non A-E, seronegative or indeterminate hepatitis; what is this deadly disease?
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:8

    Topics: Acetaminophen; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Hepatitis; Humans; Liver

2018
Acute liver failure: A review for emergency physicians.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:2

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Emergency Service, Hospital; Hepatic Encephal

2019
DAMPs and sterile inflammation in drug hepatotoxicity.
    Hepatology international, 2019, Volume: 13, Issue:1

    Topics: Acetaminophen; Alarmins; Analgesics, Non-Narcotic; Biomarkers; Chemical and Drug Induced Liver Injur

2019
Sterile inflammation in acute liver injury: myth or mystery?
    Expert review of gastroenterology & hepatology, 2015, Volume: 9, Issue:8

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cholestasis; Hepatitis; HMGB1 Protei

2015
Sterile inflammation in the liver.
    Gastroenterology, 2012, Volume: 143, Issue:5

    Topics: Acetaminophen; Adenosine Triphosphate; Caspase 1; Chemical and Drug Induced Liver Injury; Chemotaxis

2012
Etiologies of acute liver failure.
    Seminars in liver disease, 2008, Volume: 28, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Budd-Chiari Syndrome; Drug-Related Side Effects and Adverse

2008
Update in hepatology.
    Annals of internal medicine, 1999, Jan-05, Volume: 130, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Hepatitis; Hepatitis, Viral, Human; Humans; Liver Cirrhosis

1999
Treatment of acetaminophen-induced hepatitis and fulminant hepatic failure with extracorporeal sorbent-based devices.
    Advances in renal replacement therapy, 2002, Volume: 9, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Charcoal; Hemoperfusion; Hepatitis; Humans; Liver Failure;

2002
Acute liver injury.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9

    Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepati

1975
Acute hepatic necrosis and fulminant hepatic failure.
    Gut, 1973, Volume: 14, Issue:10

    Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Animals; Blood Coagulation Disorders; Brain Dise

1973

Trials

1 trial available for acetaminophen and Hepatitis

ArticleYear
[The glucuronide pattern after peroral dosage with acetanilide in chronic hepatitis and liver cirrhosis].
    Klinische Wochenschrift, 1966, Sep-01, Volume: 44, Issue:17

    Topics: Acetaminophen; Acetanilides; Glucosyltransferases; Glucuronates; Hepatitis; Humans; Liver; Liver Cir

1966

Other Studies

33 other studies available for acetaminophen and Hepatitis

ArticleYear
Use of intravenous N-acetylcysteine in acute severe hepatitis due to severe dengue infection: a case series.
    BMC infectious diseases, 2021, Sep-20, Volume: 21, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Adult; Animals; Hepatitis; Humans; Infant, Newborn; Male; Retrospecti

2021
Application of the thick extract from Maitake mushrooms for correction of metabolic disorders under the paracetamol hepatitis in rats.
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2021, Oct-22, Volume: 49, Issue:293

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Grifola; Hepatitis; Liver; Male; Met

2021
Hepatoprotective effect of methanolic extract of Iris florentina L. on paracetamol-induced liver toxicity in rats.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:5

    Topics: Acetaminophen; Animals; Hepatitis; Methanol; Plant Extracts; Rats

2022
Hepatoprotective effect of methanolic extract of Iris florentina L. on paracetamol-induced liver toxicity in rats.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:5

    Topics: Acetaminophen; Animals; Hepatitis; Methanol; Plant Extracts; Rats

2022
Hepatoprotective effect of methanolic extract of Iris florentina L. on paracetamol-induced liver toxicity in rats.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:5

    Topics: Acetaminophen; Animals; Hepatitis; Methanol; Plant Extracts; Rats

2022
Hepatoprotective effect of methanolic extract of Iris florentina L. on paracetamol-induced liver toxicity in rats.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:5

    Topics: Acetaminophen; Animals; Hepatitis; Methanol; Plant Extracts; Rats

2022
Protective effect of Chushizi (Fructus Broussonetiae) on acetaminophen-induced rat hepatitis by inhibiting the Toll-like receptor 3/c-Jun N-terminal kinase/c-jun/c-fos/janus protein tyrosine kinase/activators of transcription 3 pathway.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2020, Volume: 40, Issue:6

    Topics: Acetaminophen; Animals; Hepatitis; Humans; Liver; Male; Phosphorylation; Proto-Oncogene Proteins c-f

2020
Vitamin D deficiency exacerbates hepatic oxidative stress and inflammation during acetaminophen-induced acute liver injury in mice.
    International immunopharmacology, 2021, Volume: 97

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; H

2021
Comment on Ahsan Ali Syed et al (J Pak Med Assoc 2017; 67: 400-404) Frequency of worsening liver function in severe dengue hepatitis patients receiving paracetamol: A retrospective analysis of hospital data.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:6

    Topics: Acetaminophen; Hepatitis; Humans; Retrospective Studies; Severe Dengue

2017
Response to comment on Ahsan Ali Syed et al (J Pak Med Assoc 2017; 67: 400-404 Frequency of worsening liver function in severe dengue hepatitis patients receiving paracetamol: A retrospective analysis of hospital data.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:6

    Topics: Acetaminophen; Hepatitis; Humans; Retrospective Studies; Severe Dengue

2017
Anti-inflammatory and Antioxidant Effects of
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2020, Volume: 19, Issue:2

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Cells, Cultured;

2020
Aloe vera attenuated liver injury in mice with acetaminophen-induced hepatitis.
    BMC complementary and alternative medicine, 2014, Jul-08, Volume: 14

    Topics: Acetaminophen; Aloe; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glutathione; Hep

2014
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-19, Volume: 111, Issue:33

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Hepatitis; Humans; Ischemia; MicroRNAs; Poisoni

2014
Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats.
    BMC complementary and alternative medicine, 2014, Nov-29, Volume: 14

    Topics: Acetaminophen; Acute-Phase Proteins; Analgesics, Non-Narcotic; Animals; Antioxidants; Chemical and D

2014
Acute Liver Injury Is Independent of B Cells or Immunoglobulin M.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Acetaminophen; Acute Lung Injury; Animals; B-Lymphocytes; Chemical and Drug Induced Liver Injury; Di

2015
Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Alanine Transaminase; Apoptosis; Biomarkers; DNA Fragmentation; DN

2017
Frequency of worsening liver function in severe dengue hepatitis patients receiving paracetamol: A retrospective analysis of hospital data.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Female; Hepatitis; Humans; Liver; Liver

2017
Acute liver failure in Lithuania.
    Medicina (Kaunas, Lithuania), 2008, Volume: 44, Issue:7

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Bilirubin; Chemical and Drug Induced Liver Injury; Co

2008
Fulminant hepatitis after 10 days of acetaminophen treatment at recommended dosage in an infant.
    Pediatrics, 2011, Volume: 127, Issue:2

    Topics: Acetaminophen; Drug Administration Schedule; Hepatitis; Humans; Infant; Liver Failure, Acute; Male;

2011
[HIP/PAP, a new drug for acute liver failure].
    Medecine sciences : M/S, 2012, Volume: 28, Issue:3

    Topics: Acetaminophen; Acute Disease; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Chemical and Drug Indu

2012
Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:5

    Topics: Acetaminophen; Alanine Transaminase; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Cp

2012
Deficiency of interleukin-15 enhances susceptibility to acetaminophen-induced liver injury in mice.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Acetaminophen; Animals; Antibodies, Neutralizing; Chemical and Drug Induced Liver Injury; Disease Su

2012
Activin A and follistatin in acute liver failure.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:2

    Topics: Acetaminophen; Activins; Adolescent; Adult; Analgesics, Non-Narcotic; Biomarkers; Enzyme-Linked Immu

2003
[Studies on glycuro-conjugation in infectious hepatitis. II. The half-life of N-acetyl-p-aminophenol as test of hepatic function].
    Minerva pediatrica, 1961, Nov-24, Volume: 13

    Topics: Acetaminophen; Child; Half-Life; Hepatitis; Hepatitis A; Humans; Infant; Liver Function Tests

1961
CHRONIC TOXICITY STUDIES ON PHENACETIN, N-ACETYL-P-AMINOPHENOL (NAPA) AND ACETYLSALICYLIC ACID ON CATS.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Cats; Chemical and Drug

1964
The significance of autoantibodies and immunoglobulins in acute liver failure: a cohort study.
    Journal of hepatology, 2007, Volume: 47, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antibodies, Viral; Autoantibodies; Autoantigens; Coh

2007
[Does therapy for common liver diseases exist?].
    Revue medicale de la Suisse romande, 1983, Volume: 103, Issue:2

    Topics: Acetaminophen; Hepatitis; Hepatitis, Chronic; Hepatitis, Viral, Human; Humans; Prednisone

1983
Serum lactic dehydrogenase in the differential diagnosis of acute hepatocellular injury.
    Journal of clinical gastroenterology, 1994, Volume: 19, Issue:2

    Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug I

1994
Metal ions catalytic for free radical reactions in the plasma of patients with fulminant hepatic failure.
    Free radical research, 1994, Volume: 20, Issue:3

    Topics: Acetaminophen; Adult; Aged; Antioxidants; Chelating Agents; Copper; Female; Free Radicals; Hepatic E

1994
Morphology of hepatic stellate cells in patients with fulminant or subfulminant hepatitis requiring liver transplantation.
    Journal of submicroscopic cytology and pathology, 1996, Volume: 28, Issue:1

    Topics: Acetaminophen; Actins; Adult; Aged; Amanita; Autoimmune Diseases; Biomarkers; Cell Differentiation;

1996
A jaundiced look at the management of hepatitis?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1997, Volume: 87, Issue:7

    Topics: Acetaminophen; Alcohol Drinking; Chemical and Drug Induced Liver Injury; Female; Halothane; Hepatiti

1997
Causes of death in fulminant hepatic failure and relationship to quantitative histological assessment of parenchymal damage.
    The Quarterly journal of medicine, 1975, Volume: 44, Issue:176

    Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Amanita; Autopsy; Brain Edema; Drug Hypersensit

1975
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23--1977.
    The New England journal of medicine, 1977, Jun-09, Volume: 296, Issue:23

    Topics: Acetaminophen; Acute Disease; Adolescent; Arthritis, Juvenile; Aspirin; Brain Death; Brain Edema; Ch

1977
Hepatitis during measles in young adults: possible role of antipyretic drugs.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aminopyrine; Chemical and Drug Induced Liver Injury; Dipyrone; Fem

1989
Fulminant hepatitis. An ultrastructural study.
    Journal of hepatology, 1986, Volume: 2, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Autopsy; Chemical and Drug Induced Liver Injury; Female; Hepatitis

1986
Editorial: Towards an artificial liver.
    British medical journal, 1974, Sep-14, Volume: 3, Issue:5932

    Topics: Acetaminophen; Aspartic Acid; Brain Chemistry; Charcoal; Glutamates; Hepatic Encephalopathy; Hepatit

1974