acetaminophen has been researched along with Hepatitis A in 20 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Hepatitis A: INFLAMMATION of the LIVER in humans caused by a member of the HEPATOVIRUS genus, HUMAN HEPATITIS A VIRUS. It can be transmitted through fecal contamination of food or water.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaminophen (APAP) may cause acute liver injury with therapeutic doses in high-risk conditions such as chronic alcohol consumption or malnutrition." | 5.91 | Association between adverse outcomes of hepatitis A and acetaminophen use: A population-based cohort study. ( Chung, JW; Jang, ES; Kim, JW; Park, GC, 2023) |
| "Acetaminophen overdose and idiosyncratic drug reactions have replaced viral hepatitis as the most frequent apparent causes of acute liver failure." | 3.71 | Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. ( Blei, AT; Crippin, JS; Davern, TJ; Fontana, RJ; Han, SH; Hay, JE; Hynan, L; Larson, A; Lee, WM; McCashland, TM; Ostapowicz, G; Reisch, J; Samuel, G; Schiødt, FV; Shakil, AO, 2002) |
| " To study this, we reviewed serum enzyme patterns early in the course of acute liver injury in patients with acute viral hepatitis A and B (n = 51), ischemic hepatitis (n = 20), and acetaminophen injury (n = 26)." | 3.69 | Serum lactic dehydrogenase in the differential diagnosis of acute hepatocellular injury. ( Cassidy, WM; Reynolds, TB, 1994) |
| "Ultrastructural changes were observed in 23 consecutive patients who died from fulminant hepatic failure due to hepatitis B virus (4 cases), sporadic non-A, non-B (7), or paracetamol (acetaminophen) overdose (12) and in 3 patients with subacute hepatic necrosis of unknown cause." | 3.67 | Fulminant hepatitis. An ultrastructural study. ( Fagan, EA; McCaul, TF; Portmann, B; Tovey, G; Williams, R; Zuckerman, AJ, 1986) |
| "Acetaminophen (APAP) may cause acute liver injury with therapeutic doses in high-risk conditions such as chronic alcohol consumption or malnutrition." | 1.91 | Association between adverse outcomes of hepatitis A and acetaminophen use: A population-based cohort study. ( Chung, JW; Jang, ES; Kim, JW; Park, GC, 2023) |
| "Eighteen of twenty-four acute liver failure sera were PCR positive while six had no detectable virus." | 1.37 | What factors determine the severity of hepatitis A-related acute liver failure? ( Ajmera, V; Fontana, RJ; Forbi, JC; Ganova-Raeva, LM; Khudyakov, Y; Lee, WM; Munoz, S; Opio, CK; Restrepo, R; Taylor, R; Vaughan, G; Xia, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, GC | 1 |
| Chung, JW | 1 |
| Jang, ES | 1 |
| Kim, JW | 1 |
| Mehta, G | 1 |
| Rothstein, KD | 1 |
| Bareiss, D | 1 |
| Semela, D | 1 |
| Heim, M | 1 |
| Terracciano, L | 1 |
| Hunziker, S | 1 |
| Ajmera, V | 1 |
| Xia, G | 1 |
| Vaughan, G | 1 |
| Forbi, JC | 1 |
| Ganova-Raeva, LM | 1 |
| Khudyakov, Y | 1 |
| Opio, CK | 1 |
| Taylor, R | 1 |
| Restrepo, R | 1 |
| Munoz, S | 1 |
| Fontana, RJ | 2 |
| Lee, WM | 2 |
| Ostapowicz, G | 1 |
| Schiødt, FV | 1 |
| Larson, A | 1 |
| Davern, TJ | 1 |
| Han, SH | 1 |
| McCashland, TM | 1 |
| Shakil, AO | 1 |
| Hay, JE | 1 |
| Hynan, L | 1 |
| Crippin, JS | 1 |
| Blei, AT | 1 |
| Samuel, G | 1 |
| Reisch, J | 1 |
| Rezende, G | 1 |
| Roque-Afonso, AM | 1 |
| Samuel, D | 1 |
| Gigou, M | 1 |
| Nicand, E | 1 |
| Ferre, V | 1 |
| Dussaix, E | 1 |
| Bismuth, H | 1 |
| Féray, C | 1 |
| CAREDDU, P | 1 |
| MEREU, T | 1 |
| APOLLONIO, T | 1 |
| Rosmawati, M | 1 |
| Oldhafer, KJ | 1 |
| Gubernatis, G | 1 |
| Schlitt, HJ | 1 |
| Rodeck, B | 1 |
| Böker, K | 1 |
| Pichlmayr, R | 1 |
| Cassidy, WM | 1 |
| Reynolds, TB | 1 |
| Prieto, J | 1 |
| Barry, M | 1 |
| Sherlock, S | 1 |
| McCaul, TF | 1 |
| Fagan, EA | 1 |
| Tovey, G | 1 |
| Portmann, B | 1 |
| Williams, R | 4 |
| Zuckerman, AJ | 1 |
| Goertz, J | 1 |
| Wilkinson, SP | 1 |
| Blendis, LM | 1 |
| Knell, AJ | 1 |
| Davidson, AR | 1 |
| Kantamaneni, BD | 1 |
| Curzon, G | 1 |
| Chalstrey, LJ | 2 |
| Parbhoo, SP | 2 |
| Adjukiewicz, AB | 1 |
| James, IM | 1 |
| Hillenbrand, P | 1 |
| Kennedy, J | 1 |
| Gmyrek, D | 1 |
| Klimmt, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center Trial to Study Acute Liver Failure in Adults[NCT00518440] | 3,488 participants (Actual) | Observational | 1998-01-31 | Completed | |||
| Consumer Understanding and Use of Non-Prescription Analgesics, Investigation of Efficacy of Improved Acetaminophen Labeling[NCT01592448] | 662 participants (Actual) | Observational | 2012-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetaminophen and Hepatitis A
| Article | Year |
|---|---|
Health maintenance issues in cirrhosis.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Comorbidity; Disease Progression; Health | 2009 |
19 other studies available for acetaminophen and Hepatitis A
| Article | Year |
|---|---|
Association between adverse outcomes of hepatitis A and acetaminophen use: A population-based cohort study.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injur | 2023 |
[44 year old gardener with lower back pain, myalgia and fever].
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Analgesics, Non-Narcotic; Child; Clinical Trials as T | 2010 |
What factors determine the severity of hepatitis A-related acute liver failure?
Topics: Acetaminophen; Adult; Aged; Amino Acid Sequence; Base Sequence; Biomarkers; Chromosome Mapping; Fema | 2011 |
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Drug Overdose; Female; Hepatic Encephalopathy; | 2002 |
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Drug Overdose; Female; Hepatic Encephalopathy; | 2002 |
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Drug Overdose; Female; Hepatic Encephalopathy; | 2002 |
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Drug Overdose; Female; Hepatic Encephalopathy; | 2002 |
Summaries for patients. Acute liver failure in the United States.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Drug Overdose; Female; Hepatic Encephalopathy; | 2002 |
Viral and clinical factors associated with the fulminant course of hepatitis A infection.
Topics: Acetaminophen; Adolescent; Adult; Computer Systems; Factor V; Female; Genotype; Hepatic Encephalopat | 2003 |
[Studies on glycuro-conjugation in infectious hepatitis. II. The half-life of N-acetyl-p-aminophenol as test of hepatic function].
Topics: Acetaminophen; Child; Half-Life; Hepatitis; Hepatitis A; Humans; Infant; Liver Function Tests | 1961 |
Aetiology and classification of acute liver failure.
Topics: Acetaminophen; Disease Progression; Hepatitis A; Hepatitis B; Humans; Liver Failure, Acute; Risk Fac | 2005 |
Auxiliary partial orthotopic liver transplantation for acute liver failure: the Hannover experience.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Child; Female; Germany; Hepatitis A; Humans; Liver | 1994 |
Serum lactic dehydrogenase in the differential diagnosis of acute hepatocellular injury.
Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug I | 1994 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 23--1977.
Topics: Acetaminophen; Acute Disease; Adolescent; Arthritis, Juvenile; Aspirin; Brain Death; Brain Edema; Ch | 1977 |
Serum ferritin in patients with iron overload and with acute and chronic liver diseases.
Topics: Acetaminophen; Alcoholism; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug | 1975 |
Fulminant hepatitis. An ultrastructural study.
Topics: Acetaminophen; Adolescent; Adult; Autopsy; Chemical and Drug Induced Liver Injury; Female; Hepatitis | 1986 |
Histological appearances in fulminant hepatic failure with reference to aetiology, time of survival and role of immunological processes.
Topics: Acetaminophen; Adolescent; Adult; Aged; Cell Nucleus; Chemical and Drug Induced Liver Injury; Haloth | 1973 |
Frequency and type of renal and electrolyte disorders in fulminant hepatic failure.
Topics: Acetaminophen; Acute Kidney Injury; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatinin | 1974 |
Dopamine and serotonin metabolism in hepatic encephalopathy.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Brain; Dopamine; Fatty Acids, Nonesterified; Female; Halo | 1974 |
Circuitry and technique of extracorporeal porcine liver perfusion for the treatment of hepatic coma.
Topics: Acetaminophen; Acute Disease; Animals; Extracorporeal Circulation; Fatty Liver; Hepatic Encephalopat | 1971 |
Extracorporeal perfusion of pig liver in the treatment of acute liver failure.
Topics: Acetaminophen; Adult; Animals; Bilirubin; Brain; Chemical and Drug Induced Liver Injury; Electroence | 1971 |
[Results of an oral loading test with paracetamol in childhood infectious hepatitis].
Topics: Acetaminophen; Administration, Oral; Child; Chromatography, Thin Layer; Hepatitis A; Humans; Liver F | 1971 |