acetaminophen has been researched along with Hemorrhage in 54 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Hemorrhage: Bleeding or escape of blood from a vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5), diarrhea, acetaminophen use, increased alcohol consumption, and increased age." | 9.12 | Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis. ( Ingaszewski, A; Kerr, C; Lynd, L; Richardson, K; Shalansky, S, 2007) |
| " We determined whether paracetamol or ibuprofen use is associated with major cardiovascular events (MACE) or major bleeding in 19 120 patients with recent ischemic stroke or transient ischemic attack of mainly atherothrombotic origin included in the Prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) trial." | 7.83 | Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke. ( Amarenco, P; Bousser, MG; Chamorro, A; Fisher, M; Ford, I; Fox, KM; Gonzalez-Valcarcel, J; Hennerici, MG; Labreuche, J; Mattle, HP; Rothwell, PM; Sissani, L; Steg, PG; Vicaut, E, 2016) |
| "Acetaminophen plus codeine is effective in pain control in polytrauma patients at least in our series." | 5.14 | Acetaminophen plus codeine compared to ketorolac in polytrauma patients. ( Buccelletti, F; Calcinaro, S; Carroccia, A; De Marco, G; Franceschi, F; Gentiloni Silveri, N; Giannuzzi, R; Gilardi, E; Giupponi, B; Mancini, F; Marini, M; Marsiliani, D; Merra, G; Potenza, A, 2010) |
| "5), diarrhea, acetaminophen use, increased alcohol consumption, and increased age." | 5.12 | Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis. ( Ingaszewski, A; Kerr, C; Lynd, L; Richardson, K; Shalansky, S, 2007) |
| "Paracetamol at 4 g day(-1) induces a significant increase in INR in patients receiving a stable regimen of warfarin, increasing the risk of bleeding associated with warfarin." | 5.11 | Paracetamol: a haemorrhagic risk factor in patients on warfarin. ( Bal dit Sollier, C; Bergmann, JF; Bertrand, N; Caulin, C; Drouet, L; Mahé, I; Mazoyer, E; Simoneau, G, 2005) |
| " We defined exposure to NSAIDs as at least two records of NSAID prescriptions during early pregnancy (first 90 days of pregnancy for congenital malformations and first 19 weeks for nonmalformation outcomes) and compared against three distinct referent groups of (1) unexposed, no NSAID prescription during the 3 months before pregnancy start to end of early pregnancy; (2) acetaminophen-exposed, at least two acetaminophen prescriptions during early pregnancy (i." | 4.31 | Neonatal and maternal adverse outcomes and exposure to nonsteroidal anti-inflammatory drugs during early pregnancy in South Korea: A nationwide cohort study. ( Choe, SA; Choi, A; Choi, EY; Han, JY; Jeong, HE; Noh, Y; Shin, JY; Sung, JH; Yon, DK, 2023) |
| " The CHEST warfarin reversal guidelines describe the risks and benefits with respect to bleeding and thrombosis in the non-intentional overdose patient." | 4.12 | Massive warfarin overdose management in an adolescent patient. ( Setiawan, A; Vohra, V; Winograd, EJ, 2022) |
| "Warfarin is underutilised in frail older people because of the fear of bleeding complications." | 3.96 | Frailty and Co-Prescribing of Potentially Interacting Drugs in New Users of Warfarin. ( Bell, JS; Farinola, N; Hauta-Aho, M; Huupponen, R; Johns, S; Korhonen, MJ; Shakib, S; Teperi, S, 2020) |
| "Ketoprofen gives the highest bleeding time elevation while paracetamol gives the lowest bleeding time elevation." | 3.88 | Comparison and Impact of The Short-Term Use of Some Non-Aspirin NSAIDs on Bleeding Time of Mice. ( Sukmawan, YP, 2018) |
| " We determined whether paracetamol or ibuprofen use is associated with major cardiovascular events (MACE) or major bleeding in 19 120 patients with recent ischemic stroke or transient ischemic attack of mainly atherothrombotic origin included in the Prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) trial." | 3.83 | Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke. ( Amarenco, P; Bousser, MG; Chamorro, A; Fisher, M; Ford, I; Fox, KM; Gonzalez-Valcarcel, J; Hennerici, MG; Labreuche, J; Mattle, HP; Rothwell, PM; Sissani, L; Steg, PG; Vicaut, E, 2016) |
| "Concomitant use of warfarin and analgesics enhances the risk of bleeding." | 3.75 | [Concomitant use of warfarin, analgesics and anti-inflammatory agents]. ( Giverhaug, T; Håkonsen, GD; Pettersen, MH; Skurtveit, S, 2009) |
| "The acetaminophen (APAP)-induced hepatic centrilobular necrosis is preceded by hepatic microcirculatory dysfunction including the infiltration of erythrocytes into the space of Disse." | 3.73 | Inhibition of matrix metalloproteinases minimizes hepatic microvascular injury in response to acetaminophen in mice. ( Abril, ER; Bethea, NW; Ito, Y; McCuskey, RS, 2005) |
| "Warfarin is highly effective in preventing thromboembolism, but increases the risk of hemorrhage, particularly at an international normalized ratio (INR) greater than 4." | 3.70 | Acetaminophen and other risk factors for excessive warfarin anticoagulation. ( Heiman, H; Hylek, EM; Sheehan, MA; Singer, DE; Skates, SJ, 1998) |
| "No studies have examined postoperative pain control following transsphenoidal surgery for pituitary lesions." | 2.87 | Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery. ( Jahnke, H; Little, AS; Shepherd, DM; White, WL, 2018) |
| " A double-placebo method was used, as dosage regimens for the two treatments were different." | 2.66 | The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery. ( Olstad, OA; Skjelbred, P, 1986) |
| "L-carnitine is a cofactor in the transfer of long-chain fatty acid allowing the beta-oxidation of fatty acid in the mitochondria." | 1.34 | Hepatoprotective effect of L-carnitine against acute acetaminophen toxicity in mice. ( Atakisi, O; Citil, M; Erginsoy, S; Karapehlivan, M; Kart, A; Tunca, R; Yapar, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (29.63) | 18.7374 |
| 1990's | 9 (16.67) | 18.2507 |
| 2000's | 11 (20.37) | 29.6817 |
| 2010's | 13 (24.07) | 24.3611 |
| 2020's | 5 (9.26) | 2.80 |
| Authors | Studies |
|---|---|
| Setiawan, A | 1 |
| Vohra, V | 1 |
| Winograd, EJ | 1 |
| Choi, EY | 1 |
| Jeong, HE | 1 |
| Noh, Y | 1 |
| Choi, A | 1 |
| Yon, DK | 1 |
| Han, JY | 1 |
| Sung, JH | 1 |
| Choe, SA | 1 |
| Shin, JY | 1 |
| Hauta-Aho, M | 1 |
| Teperi, S | 1 |
| Korhonen, MJ | 1 |
| Bell, JS | 1 |
| Farinola, N | 1 |
| Johns, S | 1 |
| Shakib, S | 1 |
| Huupponen, R | 1 |
| Wang, TH | 1 |
| Kiu, KT | 1 |
| Yen, MH | 1 |
| Chang, TC | 1 |
| Stravitz, RT | 1 |
| Fontana, RJ | 1 |
| Meinzer, C | 1 |
| Durkalski-Mauldin, V | 1 |
| Hanje, AJ | 1 |
| Olson, J | 1 |
| Koch, D | 1 |
| Hamid, B | 1 |
| Schilsky, ML | 1 |
| McGuire, B | 1 |
| Ganger, D | 1 |
| Liou, I | 1 |
| Karvellas, CJ | 1 |
| Rule, JA | 1 |
| Lisman, T | 1 |
| Clasen, K | 1 |
| Reuben, A | 1 |
| Cripps, M | 1 |
| Lee, WM | 1 |
| McCormick, ZL | 1 |
| Popescu, A | 1 |
| Smith, C | 1 |
| Sukmawan, YP | 1 |
| Jadeja, RN | 1 |
| Urrunaga, NH | 1 |
| Dash, S | 1 |
| Khurana, S | 1 |
| Saxena, NK | 1 |
| Gonzalez-Valcarcel, J | 1 |
| Sissani, L | 1 |
| Labreuche, J | 1 |
| Bousser, MG | 1 |
| Chamorro, A | 1 |
| Fisher, M | 1 |
| Ford, I | 1 |
| Fox, KM | 1 |
| Hennerici, MG | 1 |
| Mattle, HP | 1 |
| Rothwell, PM | 1 |
| Steg, PG | 1 |
| Vicaut, E | 1 |
| Amarenco, P | 1 |
| Iannuccelli, C | 1 |
| Di Franco, M | 1 |
| Pulcinelli, FM | 1 |
| Shepherd, DM | 1 |
| Jahnke, H | 1 |
| White, WL | 1 |
| Little, AS | 1 |
| Autret-Leca, E | 1 |
| Håkonsen, GD | 1 |
| Pettersen, MH | 1 |
| Skurtveit, S | 1 |
| Giverhaug, T | 1 |
| Launiainen, T | 1 |
| Sajantila, A | 1 |
| Rasanen, I | 1 |
| Vuori, E | 1 |
| Ojanperä, I | 1 |
| Beyan, E | 1 |
| Beyan, C | 1 |
| Vaizoğlu, SA | 1 |
| Franceschi, F | 1 |
| Buccelletti, F | 1 |
| Marsiliani, D | 1 |
| Carroccia, A | 1 |
| Giupponi, B | 1 |
| De Marco, G | 1 |
| Gilardi, E | 1 |
| Merra, G | 1 |
| Mancini, F | 1 |
| Potenza, A | 1 |
| Giannuzzi, R | 1 |
| Calcinaro, S | 1 |
| Marini, M | 1 |
| Gentiloni Silveri, N | 1 |
| Bhaskar, E | 1 |
| Sowmya, G | 1 |
| Moorthy, S | 1 |
| Hoque, R | 1 |
| Sohail, MA | 1 |
| Salhanick, S | 1 |
| Malik, AF | 1 |
| Ghani, A | 1 |
| Robson, SC | 1 |
| Mehal, WZ | 1 |
| Woitzek, K | 1 |
| Sullivan, BP | 1 |
| Kassel, KM | 1 |
| Jone, A | 1 |
| Flick, MJ | 1 |
| Luyendyk, JP | 1 |
| O'Flaherty, JE | 1 |
| Lin, CX | 1 |
| Joshi, W | 1 |
| Connelly, NR | 1 |
| Reuben, SS | 1 |
| Wolckenhaar, M | 1 |
| Thakkar, N | 1 |
| REUTER, SH | 1 |
| MONTGOMERY, WW | 1 |
| GOULSTON, K | 2 |
| FISHLER, JJ | 1 |
| SKYRING, A | 1 |
| JENNINGS, GH | 1 |
| Ito, Y | 1 |
| Abril, ER | 1 |
| Bethea, NW | 1 |
| McCuskey, RS | 1 |
| Mahé, I | 1 |
| Bertrand, N | 1 |
| Drouet, L | 1 |
| Simoneau, G | 1 |
| Mazoyer, E | 1 |
| Bal dit Sollier, C | 1 |
| Caulin, C | 1 |
| Bergmann, JF | 1 |
| Ornetti, P | 1 |
| Ciappuccini, R | 1 |
| Tavernier, C | 1 |
| Maillefert, JF | 1 |
| Bougie, DW | 1 |
| Benito, AI | 1 |
| Sanchez-Abarca, LI | 1 |
| Torres, R | 1 |
| Birenbaum, J | 1 |
| Aster, RH | 1 |
| Yapar, K | 1 |
| Kart, A | 1 |
| Karapehlivan, M | 1 |
| Atakisi, O | 1 |
| Tunca, R | 1 |
| Erginsoy, S | 1 |
| Citil, M | 1 |
| Shalansky, S | 1 |
| Lynd, L | 1 |
| Richardson, K | 1 |
| Ingaszewski, A | 1 |
| Kerr, C | 1 |
| Bajt, ML | 1 |
| Yan, HM | 1 |
| Farhood, A | 1 |
| Jaeschke, H | 1 |
| Carrick, DG | 1 |
| Løkken, P | 2 |
| Skjelbred, P | 3 |
| Larsen, FS | 1 |
| Clemmesen, JO | 1 |
| Hansen, BA | 1 |
| MacGregor, FB | 1 |
| Albert, DM | 1 |
| Bhattacharyya, AK | 1 |
| Hall, MD | 1 |
| Brodsky, L | 2 |
| Ambühl, PM | 1 |
| Ballmer, PE | 1 |
| Krähenbühl, S | 1 |
| Radomski, K | 1 |
| Gendler, J | 1 |
| Lee, WC | 1 |
| Sharp, JF | 1 |
| Hylek, EM | 1 |
| Heiman, H | 1 |
| Skates, SJ | 1 |
| Sheehan, MA | 1 |
| Singer, DE | 1 |
| Bell, WR | 1 |
| Album, B | 1 |
| Lokken, P | 1 |
| Janbu, T | 1 |
| Nesheim, BI | 1 |
| Stage, J | 1 |
| Jensen, JH | 1 |
| Bonding, P | 1 |
| Olstad, OA | 1 |
| Caldarola, V | 1 |
| Hassett, JM | 1 |
| Hall, AH | 1 |
| Bronstein, AB | 1 |
| Kulig, KW | 1 |
| Rumack, BH | 1 |
| Clark, R | 2 |
| Rake, MO | 1 |
| Flute, PT | 1 |
| Williams, R | 2 |
| Gazzard, BG | 1 |
| Borirakchanyavat, V | 1 |
| Done, AK | 1 |
| Temple, AR | 1 |
| Vandam, LD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-Steroidal Anti-inflammatory Drugs (NSAIDS) vs. Tramadol in Pain Management After Transnasal Transsphenoidal Surgery Among Patients With Pituitary Adenomas: A Prospective Randomized Controlled Trial[NCT04611685] | 202 participants (Anticipated) | Interventional | 2020-10-31 | Recruiting | |||
| Randomized, Double-Blind, Placebo-Controlled Trial Comparing Opioid-Sparing and Opioid-Containing Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors[NCT02351700] | Phase 4 | 62 participants (Actual) | Interventional | 2015-02-01 | Completed | ||
| Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy[NCT01605903] | Phase 2 | 741 participants (Actual) | Interventional | 2012-05-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Rescue narcotic in both groups will be recorded and compared using a standard equianalgesic oral morphine equivalent (OME) calculation (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | mg (Mean) |
|---|---|
| Opioid-sparing Group | 26.3 |
| Standard Treatment Group | 62.5 |
Comparison of pain scores between two arms using Visual Analog Scale (VAS) for Pain. Units of measure are 0=No Pain, 1=Annoying, 2=Mild Pain, 3=Troublesome, 4=Nagging Pain, Uncomfortable, 5=Distressing, 6=Miserable, 7=Horrible, 8=Intense, Dreadful, 9=Unbearable, 10=Worst Possible Pain. Higher values represent a worse outcome. There are no subscales. (NCT02351700)
Timeframe: mean pain score over 48 hours
| Intervention | 0-10 units on a scale (Mean) |
|---|---|
| Opioid-sparing Group | 1.7 |
| Standard Treatment Group | 2.8 |
Length of hospital stay from time of surgery to time of discharge. (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | hours (Mean) |
|---|---|
| Opioid-sparing Group | 71.3 |
| Standard Treatment Group | 51.7 |
Epistaxis, potentially related to IV ibuprofen, will be compared between two groups (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | participants (Number) |
|---|---|
| Opioid Sparing Group | 0 |
| Standard Treatment Group | 2 |
patients with one or more bowel movement(s) in the first 48 hours after surgery (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | participants (Number) |
|---|---|
| Opioid-sparing Group | 9 |
| Standard Treatment Group | 12 |
Use of antiemetics in first 48 hours after surgery (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | dose (Mean) |
|---|---|
| Opioid-sparing Group | 9.8 |
| Standard Treatment Group | 10.1 |
Postoperative hemorrhage is defined as any history of bleeding occurring within the 14 day postoperative period. Hemorrhage will be stratified into 3 levels of severity. Level 1: includes children with a history of postoperative bleeding evaluated and/or treated by a physician in the emergency room, inpatient unit or operating room; Level 2: children requiring inpatient admission for postoperative bleeding regardless of the need for operative intervention; Level 3: children requiring inpatient admission and return to the operating room for control of post-tonsillectomy hemorrhage. (NCT01605903)
Timeframe: Data about post-tonsillectomy bleeding will be obtained after the end of a 14-day postoperative period.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment With Ibuprofen | 10 |
| Treatment With Acetaminophen | 4 |
3 reviews available for acetaminophen and Hemorrhage
| Article | Year |
|---|---|
Fact Finders for Patient Safety: Risk of Bleeding with Nonaspirin Nonsteroidal Anti-inflammatory Drugs Before Spine Procedures.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Hemorrhage; Humans; Risk; Spine; Time Factor | 2018 |
[Fulminant hepatitis: pathogenesis, clinical aspects and management].
Topics: Acetaminophen; Adult; Brain Edema; Chemical and Drug Induced Liver Injury; Hemorrhage; Hepatic Encep | 1994 |
Treatment of salicylate poisoning.
Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Alkalosis, Respiratory; Aspirin | 1971 |
15 trials available for acetaminophen and Hemorrhage
| Article | Year |
|---|---|
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Acetaminophen plus codeine compared to ketorolac in polytrauma patients.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, | 2010 |
[Ibuprofen/paracetamol combination therapy is more effective than monotherapy in knee pain, but increases bleeding risk].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pai | 2012 |
Does ketamine or magnesium affect posttonsillectomy pain in children?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child | 2003 |
An evaluation of the safety and efficacy of administering rofecoxib for postoperative pain management.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2003 |
Paracetamol: a haemorrhagic risk factor in patients on warfarin.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anticoagulants; Contraindic | 2005 |
Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis.
Topics: Acetaminophen; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Canada; Coenzymes; Compl | 2007 |
Analgesic and anti-inflammatory effects of paracetamol evaluated by bilateral oral surgery.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents; Body Temperature; Clinical Trials as Top | 1980 |
The effect of post-operative diet on recovery in the first twelve hours after tonsillectomy and adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Beverages; Child; Child Behavior; Child, Preschool; Diet; | 1995 |
The effect of post-operative instructions on recovery after tonsillectomy and adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Child; Child, Preschool; Diet Therapy; Female; Hemorrhage; | 1993 |
Acetylsalicylic acid vs paracetamol: effects on post-operative course.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Clinical Trials as Topic; Female; Hemorrhage; Humans; Mal | 1977 |
Effect of acetylsalicylic acid, paracetamol, and placebo on pain and blood loss in dysmenorrhoeic women.
Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; | 1978 |
Post-tonsillectomy haemorrhage and analgesics. A comparative study of acetylsalicylic acid and paracetamol.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Hemorrhage; Hemostasis, | 1988 |
The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Female; Hemorrhage; Humans; Indoprofen; | 1986 |
A controlled trial of heparin therapy in the coagulation defect of paracetamol-induced hepatic necrosis.
Topics: Acetaminophen; Adolescent; Adult; Blood Coagulation Disorders; Blood Transfusion; Chemical and Drug | 1974 |
36 other studies available for acetaminophen and Hemorrhage
| Article | Year |
|---|---|
Massive warfarin overdose management in an adolescent patient.
Topics: Acetaminophen; Adolescent; Anticoagulants; Child; Ethanol; Hemorrhage; Humans; International Normali | 2022 |
Neonatal and maternal adverse outcomes and exposure to nonsteroidal anti-inflammatory drugs during early pregnancy in South Korea: A nationwide cohort study.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Female; Hemorrhage; Humans; | 2023 |
Frailty and Co-Prescribing of Potentially Interacting Drugs in New Users of Warfarin.
Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Clo | 2020 |
Comparison of the short-term outcomes of using DST and PPH staplers in the treatment of grade III and IV hemorrhoids.
Topics: Acetaminophen; Anal Canal; Analgesics; Anus Diseases; Constriction, Pathologic; Equipment Design; Fe | 2020 |
Coagulopathy, Bleeding Events, and Outcome According to Rotational Thromboelastometry in Patients With Acute Liver Injury/Failure.
Topics: Acetaminophen; Adolescent; Adult; Aged; Blood Coagulation Disorders; Chemical and Drug Induced Liver | 2021 |
Comparison and Impact of The Short-Term Use of Some Non-Aspirin NSAIDs on Bleeding Time of Mice.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Hemorrhage; Ketoprof | 2018 |
Withaferin-A Reduces Acetaminophen-Induced Liver Injury in Mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Cell Line; Cell Survival; Chemical a | 2015 |
Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Brain Ischemia; Cardiovascular Diseases; Female; Hemo | 2016 |
Letter by Iannuccelli et al Regarding Article, "Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke".
Topics: Acetaminophen; Brain Ischemia; Hemorrhage; Humans; Ibuprofen; Stroke | 2016 |
[Drugs news].
Topics: Acetaminophen; Acupuncture; Asthma; Child; Glucocorticoids; Hemorrhage; Humans; Placebo Effect; Resp | 2009 |
[Concomitant use of warfarin, analgesics and anti-inflammatory agents].
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2009 |
Adverse interaction of warfarin and paracetamol: evidence from a post-mortem study.
Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Aged; Analgesics, Non-Narcotic; Analgesics, | 2010 |
Adverse interaction of warfarin and paracetamol: evidence from a post-mortem study.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Emergency | 2010 |
Musculoskeletal manifestations of dengue fever: is there a changing pattern?
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dengue Viru | 2012 |
P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Antigens, CD; Antipyretics; Apyrase; Cells, Cultured; Chemical and Drug Indu | 2012 |
Fibrin(ogen)-independent role of plasminogen activators in acetaminophen-induced liver injury.
Topics: Acetaminophen; Alanine Transaminase; Animals; Antithrombin III; Blood Coagulation; Chemical and Drug | 2012 |
ASPIRIN VS ACETAMINOPHEN AFTER TONSILLECTOMY. A COMPARATIVE DOUBLE-BLIND CLINICAL STUDY.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspiri | 1964 |
GASTRO-INTESTINAL BLEEDING.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Chromium Isotopes; Gastr | 1964 |
EFFECTS OF ASPIRIN, ACETAMINOPHEN, AND SALICYLAMIDE ON GASTRIC MUCOSA OF DOGS.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Dogs; Gastric Mucosa; Ga | 1964 |
EFFECT OF PARACETAMOL (N-ACETYL-P-AMINOPHENOL) ON GASTROINTESTINAL BLEEDING.
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Occult Blood; Pharmacology; | 1964 |
PARACETAMOL OR ASPIRIN?
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Toxicology | 1965 |
Inhibition of matrix metalloproteinases minimizes hepatic microvascular injury in response to acetaminophen in mice.
Topics: Acetaminophen; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Enzyme Inhibit | 2005 |
Interaction between paracetamol and oral anticoagulants.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anticoagulants; Drug Interactions; Hemorrhage; Humans | 2005 |
Acute thrombocytopenia caused by sensitivity to the glucuronide conjugate of acetaminophen.
Topics: Acetaminophen; Autoantibodies; Child, Preschool; Female; Glucuronides; Hemorrhage; Humans; Platelet | 2007 |
Hepatoprotective effect of L-carnitine against acute acetaminophen toxicity in mice.
Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Ami | 2007 |
Plasminogen activator inhibitor-1 limits liver injury and facilitates regeneration after acetaminophen overdose.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Li | 2008 |
Salicylates and post-tonsillectomy haemorrhage.
Topics: Acetaminophen; Aspirin; Hemorrhage; Humans; Pain, Postoperative; Postoperative Complications; Prospe | 1984 |
[Hemorrhagic pancreatitis. A rare complication of paracetamol poisoning].
Topics: Acetaminophen; Drug Overdose; Fatal Outcome; Female; Hemorrhage; Humans; Middle Aged; Pancreatitis; | 1995 |
Post-operative morbidity following paediatric tonsillectomy; a comparison of bipolar diathermy dissection and blunt dissection.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Child; Child, Preschool; Diathermy; Female; Hemorrhage; Hu | 1995 |
Complications of paediatric tonsillectomy post-discharge.
Topics: Acetaminophen; Adolescent; Child; Child Behavior; Child, Preschool; Consumer Behavior; Earache; Fema | 1996 |
Acetaminophen and other risk factors for excessive warfarin anticoagulation.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analgesics, Non-Narcotic; Anticoagu | 1998 |
Acetaminophen and warfarin: undesirable synergy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticoagulants; Drug Synergism; Hemorrhage; Humans; Risk; W | 1998 |
Acetaminophen and warfarin.
Topics: Acetaminophen; Anticoagulants; Drug Interactions; Hemorrhage; Humans; International Normalized Ratio | 1998 |
Hemorrhagic pancreatitis associated with acetaminophen overdose.
Topics: Abdomen, Acute; Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Hemorrhage; Humans; Ki | 1986 |
Coagulation abnormalities in acute liver failure; pathogenetic and therapeutic implications.
Topics: Acetaminophen; Acute Disease; Bilirubin; Biopsy; Blood Coagulation Disorders; Blood Coagulation Test | 1973 |
Analgetic drugs--the mild analgetics.
Topics: Acetaminophen; Acetanilides; Administration, Oral; Analgesics; Aspirin; Codeine; Dextropropoxyphene; | 1972 |