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acetaminophen and Heart Disease, Ischemic

acetaminophen has been researched along with Heart Disease, Ischemic in 10 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"35 mmol/l acetaminophen administered 10 min after the onset of a 20-min period of global, low-flow myocardial ischemia was investigated."7.71Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms. ( Merrill, GF, 2002)
"Acetaminophen is a commonly used alternative to nonsteroidal anti-inflammatory drugs, which have recently been demonstrated to increase mortality after acute myocardial infarction (AMI)."5.33Role of acetaminophen in acute myocardial infarction. ( Gorman, JH; Gorman, RC; Hinmon, R; Jackson, BM; Leshnower, BG; Parish, LM; Plappert, T; Sakamoto, H; Zeeshan, A, 2006)
"Acetaminophen was administered acutely at the onset of reperfusion after 20 min of low-flow, global myocardial ischemia in isolated, perfused guinea pig hearts (Langendorff) to evaluate its influence in the postischemia, reperfused myocardium."3.71Acetaminophen in the post-ischemia reperfused myocardium. ( Golfetti, R; Merrill, G; Rork, T; Spiler, N; VanDyke, K, 2002)
"The acute administration of acetaminophen to isolated, perfused guinea pig hearts appears to have cardioprotective effects against the injury/mechanical dysfunction caused by global, low-flow, myocardial ischemia and reperfusion."3.71Antioxidant properties of acetaminophen and cardioprotection. ( Goldberg, E; Merrill, GF, 2001)
"35 mmol/l acetaminophen administered 10 min after the onset of a 20-min period of global, low-flow myocardial ischemia was investigated."3.71Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms. ( Merrill, GF, 2002)
"Acetaminophen or paracetamol, a commonly used over-the-counter analgesic, is known to elicit severe adverse reactions when taken in overdose, chronically at therapeutic dosage or, sporadically, following single assumptions of a therapeutic dose."1.39Possible fatal acetaminophen intoxication with atypical clinical presentation. ( Carbone, A; Chiarotti, M; d'Aloja, E; De-Giorgio, F; Lodise, M; Valerio, L, 2013)
"Acetaminophen is a commonly used alternative to nonsteroidal anti-inflammatory drugs, which have recently been demonstrated to increase mortality after acute myocardial infarction (AMI)."1.33Role of acetaminophen in acute myocardial infarction. ( Gorman, JH; Gorman, RC; Hinmon, R; Jackson, BM; Leshnower, BG; Parish, LM; Plappert, T; Sakamoto, H; Zeeshan, A, 2006)
" We conclude that chronic administration of acetaminophen provides cardioprotection to the postischemic, reperfused rodent myocardium."1.32Chronically administered acetaminophen and the ischemia/reperfused myocardium. ( Golfetti, R; Merrill, G; Rork, T, 2003)
"Acetaminophen is a phenol with antioxidant properties, but little is known about its actions on the mammalian myocardium and coronary circulation."1.31Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion. ( McConnell, P; Merrill, G; Powell, S; Vandyke, K, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (80.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De-Giorgio, F1
Lodise, M1
Chiarotti, M1
d'Aloja, E1
Carbone, A1
Valerio, L1
Jacob, S1
Cherian, P1
Preusz, C1
Kovacs, R1
Mohr, NM1
Fuller, BM1
Skrupky, LP1
Moy, H1
Alunday, R1
Micek, ST1
Fagley, RE1
Golfetti, R2
VanDyke, K2
Rork, T2
Spiler, N1
Merrill, G3
Spiler, NM1
Rork, TH1
Merrill, GF3
Leshnower, BG1
Sakamoto, H1
Zeeshan, A1
Parish, LM1
Hinmon, R1
Plappert, T1
Jackson, BM1
Gorman, JH1
Gorman, RC1
McConnell, P1
Powell, S1
Goldberg, E1

Reviews

1 review available for acetaminophen and Heart Disease, Ischemic

ArticleYear
An old drug with a new purpose: cardiovascular actions of acetaminophen (paracetamol).
    Current drug targets. Cardiovascular & haematological disorders, 2005, Volume: 5, Issue:5

    Topics: Acetaminophen; Animals; Cardiotonic Agents; Humans; Myocardial Ischemia; Myocardium

2005

Other Studies

9 other studies available for acetaminophen and Heart Disease, Ischemic

ArticleYear
Possible fatal acetaminophen intoxication with atypical clinical presentation.
    Journal of forensic sciences, 2013, Volume: 58, Issue:5

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Disseminated Intravascular Coagulation

2013
Heartbreaking case of acetaminophen poisoning.
    Circulation, 2008, Sep-30, Volume: 118, Issue:14

    Topics: Acetaminophen; Adult; Electrocardiography; Fatal Outcome; Female; Humans; Myocardial Ischemia

2008
Clinical and demographic factors associated with antipyretic use in gram-negative severe sepsis and septic shock.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:10

    Topics: Academic Medical Centers; Acetaminophen; Adult; Aged; Antipyretics; Bacteremia; Cohort Studies; Fema

2011
Acetaminophen in the post-ischemia reperfused myocardium.
    Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:11

    Topics: Acetaminophen; Animals; Creatine Kinase; Female; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myoc

2002
Chronically administered acetaminophen and the ischemia/reperfused myocardium.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:6

    Topics: Acetaminophen; Animals; Cardiotonic Agents; Coronary Circulation; Creatine Kinase; Female; Guinea Pi

2003
Role of acetaminophen in acute myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:6

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Animals; Apoptosis; Body Temperature; Corona

2006
Coronary and myocardial effects of acetaminophen: protection during ischemia-reperfusion.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Acetaminophen; Animals; Coronary Circulation; Coronary Vessels; Cytoprotection; Dose-Response Relati

2001
Antioxidant properties of acetaminophen and cardioprotection.
    Basic research in cardiology, 2001, Volume: 96, Issue:5

    Topics: Acetaminophen; Action Potentials; Analgesics, Non-Narcotic; Animals; Antioxidants; Cardiotonic Agent

2001
Acetaminophen and low-flow myocardial ischemia: efficacy and antioxidant mechanisms.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:4

    Topics: Acetaminophen; Animals; Antioxidants; Cardiotonic Agents; Disease Models, Animal; Guinea Pigs; Heart

2002