acetaminophen and HMN (Hereditary Motor Neuropathy) Proximal Type I studies

acetaminophen and HMN (Hereditary Motor Neuropathy) Proximal Type I

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

Excerpt	Relevance	Reference
"We determined acetaminophen protein adduct levels, in combination with a literature review and systematic evaluation of the cases, using the Roussel Uclaf Causality Assessment Method for drug-induced liver injury to assess causality between recommended acetaminophen dosing and acute liver failure in two children with myopathies."	1.37	Acute liver failure after recommended doses of acetaminophen in patients with myopathies. ( Ceelie, I; de Wildt, SN; Gijsen, V; Ito, S; James, LP; Koren, G; Mathot, RA; Tesselaar, CD; Tibboel, D, 2011)

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

1 (100.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Ceelie, I	1
James, LP	1
Gijsen, V	1
Mathot, RA	1
Ito, S	1
Tesselaar, CD	1
Tibboel, D	1
Koren, G	1
de Wildt, SN	1

Studies

Ceelie, I

James, LP

Gijsen, V

Mathot, RA

Ito, S

Tesselaar, CD

Tibboel, D

Koren, G

de Wildt, SN

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658]	Phase 4	48 participants (Anticipated)	Interventional	2019-02-18	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658]

Phase 4

48 participants (Anticipated)

Interventional

2019-02-18

Recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for acetaminophen and HMN (Hereditary Motor Neuropathy) Proximal Type I

Article	Year
Acute liver failure after recommended doses of acetaminophen in patients with myopathies. Critical care medicine, 2011, Volume: 39, Issue:4 Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Female; Humans; Intensive Care Units, Pe	2011

Article

Year

Acute liver failure after recommended doses of acetaminophen in patients with myopathies.

Critical care medicine, 2011, Volume: 39, Issue:4

Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Female; Humans; Intensive Care Units, Pe

2011