Page last updated: 2024-10-22

acetaminophen and HIV Coinfection

acetaminophen has been researched along with HIV Coinfection in 14 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Hypothermia is an uncommon side effect of acetaminophen."7.71[Acetaminophen-induced hypothermia, an AIDS related side-effect? About 4 cases]. ( Amaniou, M; Denes, E; Merle, L; Rogez, JP; Weinbreck, P, 2002)
" In total, 1196 samples from 241 individuals across four independent cohorts were profiled: healthy volunteers receiving acetaminophen, patients with human immunodeficiency virus and/or tuberculosis receiving treatment, DILI cases originating from a wide spectrum of drugs, and healthy volunteers receiving heparins."3.85Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury. ( Aderaye, G; Aklillu, E; Andrade, RJ; Arber, N; Bachmann, J; Drobin, K; Fier, I; Göpfert, J; Gry, M; Kampf, C; Lindberg, J; Lucena, MI; Makonnen, E; Mikus, M; Nilsson, P; Perazzo, H; Poynard, T; Roach, J; Schuppe-Koistinen, I; Schwenk, JM; Stephens, C; Uhlén, M; Watkins, PB; Yimer, G, 2017)
"Hypothermia is an uncommon side effect of acetaminophen."3.71[Acetaminophen-induced hypothermia, an AIDS related side-effect? About 4 cases]. ( Amaniou, M; Denes, E; Merle, L; Rogez, JP; Weinbreck, P, 2002)
"Routine oral dosing practices in a SSA hospital resulted in substantial underexposure to paracetamol."1.46Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study. ( Bos, JC; Mathôt, RAA; Mistício, MC; Nunguiane, G; Prins, JM; van Hest, RM, 2017)
"The target population was HIV and AIDS patients who had been using the primary health clinic for chronic pain management."1.39The management of HIV- and AIDS-related pain in a primary health clinic in Tshwane, South Africa. ( Dreyer Wright, SC; Makua, MR; Maree, JE, 2013)
"No effect of disease state, AIDS vs asymptomatic HIV positive vs control, on APAP glucuronidation or sulphation was observed."1.30Glucuronidation and sulphation of paracetamol in HIV-positive patients and patients with AIDS. ( Di Girolamo, A; O'Neil, WM; Pezzullo, JC; Tsoukas, CM; Wainer, IW, 1999)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's5 (35.71)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Sher, H1
Sharif, H1
Zaheer, T1
Khan, SA1
Ali, A1
Javed, H1
Javed, A1
Bos, JC1
Mistício, MC1
Nunguiane, G1
Mathôt, RAA1
van Hest, RM1
Prins, JM1
Maree, JE1
Dreyer Wright, SC1
Makua, MR1
Edelman, EJ1
Gordon, KS1
Lo Re, V1
Skanderson, M1
Fiellin, DA1
Justice, AC1
Mikus, M1
Drobin, K1
Gry, M1
Bachmann, J1
Lindberg, J1
Yimer, G1
Aklillu, E1
Makonnen, E1
Aderaye, G1
Roach, J1
Fier, I1
Kampf, C1
Göpfert, J1
Perazzo, H1
Poynard, T1
Stephens, C1
Andrade, RJ1
Lucena, MI1
Arber, N1
Uhlén, M1
Watkins, PB2
Schwenk, JM1
Nilsson, P1
Schuppe-Koistinen, I1
Jih, JS1
Chen, YJ1
Lin, MW1
Chen, YC1
Chen, TJ1
Huang, YL1
Chen, CC1
Lee, DD1
Chang, YT1
Wang, WJ1
Liu, HN1
Denes, E1
Amaniou, M1
Rogez, JP1
Weinbreck, P1
Merle, L1
Shangase, L1
Feller, L1
Blignaut, E1
Seeff, LB1
Atkuri, KR1
Mantovani, JJ1
Herzenberg, LA2
Gabriel, CM1
Minor, JR1
Vogel, S1
Piscitelli, SC1
O'Neil, WM1
Pezzullo, JC1
Di Girolamo, A1
Tsoukas, CM1
Wainer, IW1
Nicholas, SW1
Steffe, EM1
King, JH1
Inciardi, JF1
Flynn, NF1
Goldstein, E1
Tonjes, TS1
Benet, LZ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Liver Injury by Statins in Coronary Heart Disease (CHD) Patients With History of Hepatitis B Virus (HBV) Infection[NCT02808299]600 participants (Anticipated)Observational2016-12-31Not yet recruiting
Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity[NCT02353455]300 participants (Anticipated)Observational2013-03-31Recruiting
A Multi-center, Randomized, Double-blind, Active Control Phase II Study to Investigate Multiple Dosage and Treatments of Magnesium Isoglycyrrhizinate Injection to Cure the Acute Drug-induced Liver Injury[NCT02734966]Phase 2174 participants (Actual)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetaminophen and HIV Coinfection

ArticleYear
N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency.
    Current opinion in pharmacology, 2007, Volume: 7, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Antidotes; Controlled Clinical Trials as Topic; Cysteine; Cystic Fibr

2007

Other Studies

13 other studies available for acetaminophen and HIV Coinfection

ArticleYear
Employing computational tools to design a multi-epitope vaccine targeting human immunodeficiency virus-1 (HIV-1).
    BMC genomics, 2023, May-24, Volume: 24, Issue:1

    Topics: Acetaminophen; Animals; Epitopes, B-Lymphocyte; Epitopes, T-Lymphocyte; HIV Infections; HIV-1; Human

2023
Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study.
    BMC research notes, 2017, Dec-04, Volume: 10, Issue:1

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Biological Availability; Critical Illness; Cro

2017
The management of HIV- and AIDS-related pain in a primary health clinic in Tshwane, South Africa.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2013, Volume: 14, Issue:2

    Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Analgesics, Non-Narcotic

2013
Acetaminophen receipt among HIV-infected patients with advanced hepatic fibrosis.
    Pharmacoepidemiology and drug safety, 2013, Volume: 22, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Cross-Sectional Studies; Drug Prescriptions; Drug Utilizati

2013
Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:1

    Topics: Acetaminophen; Adult; Alanine Transaminase; Antigens, CD; Biomarkers; Cadherins; Chemical and Drug I

2017
Epidemiological features and costs of herpes zoster in Taiwan: a national study 2000 to 2006.
    Acta dermato-venereologica, 2009, Volume: 89, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; An

2009
[Acetaminophen-induced hypothermia, an AIDS related side-effect? About 4 cases].
    Annales de medecine interne, 2002, Volume: 153, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; HIV Infections; Humans; Hypothermia; Injecti

2002
Necrotising ulcerative gingivitis/periodontitis as indicators of HIV-infection.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2004, Volume: 59, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Infective Agents; Anti-Infective Ag

2004
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Drug-induced liver injury: summary of a single topic clinical research conference.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Chemical and Drug Induced Liver Injury; Child; Genetic Predisposit

2006
Supportive care during aldesleukin therapy for patients infected with human immunodeficiency virus.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, May-15, Volume: 54, Issue:10

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Female; Fever; HIV Infections; Humans;

1997
Glucuronidation and sulphation of paracetamol in HIV-positive patients and patients with AIDS.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:6

    Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Adult; Cross-Sectional Studies; Disease Progressi

1999
Guidelines for the care of children and adolescents with HIV infection. Management of the HIV-positive child with fever.
    The Journal of pediatrics, 1991, Volume: 119, Issue:1 Pt 2

    Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Child; Fever; HIV Infections; HIV Seropositivity;

1991
The effect of acetaminophen on zidovudine metabolism in HIV-infected patients.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:7

    Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combina

1990