Page last updated: 2024-10-22

acetaminophen and Glioma

acetaminophen has been researched along with Glioma in 5 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" Using cultures of rodent and human malignant glioma cell lines, we demonstrated that millimolar concentrations of acetylsalicylate, acetaminophen, and ibuprofen all significantly reduce cell numbers after several days of culture."7.70Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. ( Casper, D; Jaggernauth, WA; LaSala, PA; Lekhraj, R; Pidel, A; Rowe, JD; Tribius, S; Werner, P; Yaparpalvi, US, 2000)
" In this study, we investigated the effect of chemically unrelated NSAIDs in the proliferation of glioma cell lines and the possible mechanisms involved in indomethacin-mediated inhibition of proliferation in glioma cells lines."3.73Nonsteroidal anti-inflammatory drugs inhibit the growth of C6 and U138-MG glioma cell lines. ( Battastini, AM; Bernardi, A; Delgado-Cañedo, A; Jacques-Silva, MC; Lenz, G, 2006)
" Using cultures of rodent and human malignant glioma cell lines, we demonstrated that millimolar concentrations of acetylsalicylate, acetaminophen, and ibuprofen all significantly reduce cell numbers after several days of culture."3.70Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. ( Casper, D; Jaggernauth, WA; LaSala, PA; Lekhraj, R; Pidel, A; Rowe, JD; Tribius, S; Werner, P; Yaparpalvi, US, 2000)
"Glioma and meningioma are uncommon tumors of the brain with few known risk factors."1.43Analgesic use and the risk of primary adult brain tumor. ( Anic, GA; Chowdhary, SA; Egan, KM; Forsyth, PA; LaRocca, RV; Nabors, LB; Olson, JJ; Rozmeski, CM; Thompson, RC; Thompson, ZJ, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Egan, KM1
Nabors, LB1
Thompson, ZJ1
Rozmeski, CM1
Anic, GA1
Olson, JJ1
LaRocca, RV1
Chowdhary, SA1
Forsyth, PA1
Thompson, RC1
Wan, J1
Bae, MA2
Song, BJ2
Bernardi, A1
Jacques-Silva, MC1
Delgado-Cañedo, A1
Lenz, G1
Battastini, AM1
Casper, D1
Lekhraj, R1
Yaparpalvi, US1
Pidel, A1
Jaggernauth, WA1
Werner, P1
Tribius, S1
Rowe, JD1
LaSala, PA1
Pie, JE1

Other Studies

5 other studies available for acetaminophen and Glioma

ArticleYear
Analgesic use and the risk of primary adult brain tumor.
    European journal of epidemiology, 2016, Volume: 31, Issue:9

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non

2016
Acetoaminophen-induced accumulation of 8-oxodeoxyguanosine through reduction of Ogg1 DNA repair enzyme in C6 glioma cells.
    Experimental & molecular medicine, 2004, Feb-29, Volume: 36, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cell Line, Tumor; Deoxyguanosine; DNA; DNA Damage;

2004
Nonsteroidal anti-inflammatory drugs inhibit the growth of C6 and U138-MG glioma cell lines.
    European journal of pharmacology, 2006, Feb-27, Volume: 532, Issue:3

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferatio

2006
Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture.
    Journal of neuro-oncology, 2000, Volume: 46, Issue:3

    Topics: Acetaminophen; Adult; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Brain; Brain Neoplasms; Ce

2000
Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway.
    Molecular pharmacology, 2001, Volume: 60, Issue:4

    Topics: Acetaminophen; Acetanilides; Analgesics; Analgesics, Non-Narcotic; Androstadienes; Animals; Apoptosi

2001