acetaminophen has been researched along with Fibrosis in 9 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our patient presented with intentional acetaminophen overdose, received a transplant from a brain dead donor, and was confirmed brain dead 12 days posttransplant." | 5.12 | A Liver's Iliad: Liver Graft Retransplant to a Second Recipient After Brain Death in a First Recipient. ( Boira, MA; Ferreira, L; Maguire, D; Nair, S; Stafford, A, 2021) |
| "DILI is an uncommon indication for hospitalization carrying lower risks of death except in patients with non-acetaminophen, cirrhosis, elderly or concomitant diseases." | 3.83 | The incidence, presentation, outcomes, risk of mortality and economic data of drug-induced liver injury from a national database in Thailand: a population-base study. ( Pan-Ngum, W; Phaosawasdi, K; Poovorawan, K; Sobhonslidsuk, A; Soonthornworasiri, N, 2016) |
| " As model toxic compounds lipopolysaccharide (LPS, inducing inflammation), paracetamol (necrosis), carbon tetrachloride (CCl(4), fibrosis and necrosis) and gliotoxin (apoptosis) were used." | 3.74 | Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity. ( Bauerschmidt, S; Draaisma, AL; Elferink, MG; Groothuis, GM; Merema, MT; Olinga, P; Polman, J; Schoonen, WG, 2008) |
| "Focal segmental glomerulosclerosis is a critical pathological lesion in metabolic syndrome-associated kidney disease that, if allowed to proceed unchecked, can lead to renal failure." | 1.42 | Acetaminophen attenuates glomerulosclerosis in obese Zucker rats via reactive oxygen species/p38MAPK signaling pathways. ( Arvapalli, R; Blough, E; Dai, X; Leidy, JW; Masannat, Y; Triest, WE; Wang, C; Wu, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Boira, MA | 1 |
| Ferreira, L | 1 |
| Nair, S | 1 |
| Stafford, A | 1 |
| Maguire, D | 1 |
| Schunke, KJ | 1 |
| Coyle, L | 1 |
| Merrill, GF | 1 |
| Denhardt, DT | 1 |
| Wang, C | 2 |
| Blough, ER | 1 |
| Arvapalli, R | 2 |
| Dai, X | 2 |
| Paturi, S | 1 |
| Manne, N | 1 |
| Addagarla, H | 1 |
| Triest, WE | 2 |
| Olajide, O | 1 |
| Wu, M | 2 |
| Blough, E | 1 |
| Leidy, JW | 1 |
| Masannat, Y | 1 |
| Sobhonslidsuk, A | 1 |
| Poovorawan, K | 1 |
| Soonthornworasiri, N | 1 |
| Pan-Ngum, W | 1 |
| Phaosawasdi, K | 1 |
| Yamamotoya, T | 1 |
| Nakatsu, Y | 1 |
| Matsunaga, Y | 1 |
| Fukushima, T | 1 |
| Yamazaki, H | 1 |
| Kaneko, S | 1 |
| Fujishiro, M | 1 |
| Kikuchi, T | 1 |
| Kushiyama, A | 1 |
| Tokunaga, F | 1 |
| Asano, T | 1 |
| Sakoda, H | 1 |
| Kubota, M | 1 |
| Shinoda, A | 1 |
| Iguchi, K | 1 |
| Takahashi, Y | 1 |
| Usui, S | 1 |
| Kiho, T | 1 |
| Hirano, K | 1 |
| Obel, G | 1 |
| Krogdahl, A | 1 |
| Thygesen, T | 1 |
| Godballe, C | 1 |
| Elferink, MG | 1 |
| Olinga, P | 1 |
| Draaisma, AL | 1 |
| Merema, MT | 1 |
| Bauerschmidt, S | 1 |
| Polman, J | 1 |
| Schoonen, WG | 1 |
| Groothuis, GM | 1 |
2 reviews available for acetaminophen and Fibrosis
| Article | Year |
|---|---|
A Liver's Iliad: Liver Graft Retransplant to a Second Recipient After Brain Death in a First Recipient.
Topics: Acetaminophen; Brain Death; Fibrosis; Graft Survival; Humans; Liver Cirrhosis; Liver Neoplasms; Live | 2021 |
Juvenile mandibular chronic osteomyelitis: 3 cases and a literature review.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Child; Chronic Disease; Delayed Diagnosis; D | 2013 |
7 other studies available for acetaminophen and Fibrosis
| Article | Year |
|---|---|
Acetaminophen attenuates doxorubicin-induced cardiac fibrosis via osteopontin and GATA4 regulation: reduction of oxidant levels.
Topics: Acetaminophen; Animals; Cell Survival; Cells, Cultured; Doxorubicin; Drug Interactions; Fibrosis; GA | 2013 |
Metabolic syndrome-induced tubulointerstitial injury: role of oxidative stress and preventive effects of acetaminophen.
Topics: Acetaminophen; Actins; Analgesics, Non-Narcotic; Animals; Apoptosis; bcl-2-Associated X Protein; Cas | 2013 |
Acetaminophen attenuates glomerulosclerosis in obese Zucker rats via reactive oxygen species/p38MAPK signaling pathways.
Topics: Acetaminophen; Animals; Chemokine CCL2; Connective Tissue Growth Factor; Fibronectins; Fibrosis; Gen | 2015 |
The incidence, presentation, outcomes, risk of mortality and economic data of drug-induced liver injury from a national database in Thailand: a population-base study.
Topics: Acetaminophen; Adult; Age Factors; Aged; Analgesics, Non-Narcotic; Antitubercular Agents; Chemical a | 2016 |
Reduced SHARPIN and LUBAC Formation May Contribute to CClâ‚„- or Acetaminophen-Induced Liver Cirrhosis in Mice.
Topics: Acetaminophen; Animals; Apoptosis; Carbon Tetrachloride; Carrier Proteins; Cell Line, Tumor; Disease | 2017 |
Up-regulation of the lysyl hydroxylase 2 gene by acetaminophen and isoniazid is modulated by transcription factor c-Myb.
Topics: Acetaminophen; Binding Sites; Blotting, Western; Chemical and Drug Induced Liver Injury; Fibrosis; G | 2010 |
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity.
Topics: Acetaminophen; Animals; Apoptosis; Carbon Tetrachloride; Down-Regulation; Fibrosis; Forecasting; Gli | 2008 |