acetaminophen has been researched along with Fibromyalgia in 19 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg tramadol/325 mg acetaminophen) for the treatment of fibromyalgia pain." | 9.10 | Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study. ( Bennett, RM; Kamin, M; Karim, R; Rosenthal, N, 2003) |
| "The effect of the selective serotonin reuptake inhibitor citalopram was studied in a randomized, double-blind, placebo-controlled, 4-month trial in patients with the fibromyalgia syndrome (FMS) who all fulfilled the American College of Rheumatology criteria." | 9.09 | Citalopram in patients with fibromyalgia--a randomized, double-blind, placebo-controlled study. ( Anderberg, UM; Marteinsdottir, I; von Knorring, L, 2000) |
| "To study the efficacy of 5-hydroxytryptamine type 3 receptor (5-HT-3R) antagonist (ondansetron) vs paracetamol in primary fibromyalgia (FM) syndrome." | 9.08 | Pathogenetic aspects of responsiveness to ondansetron (5-hydroxytryptamine type 3 receptor antagonist) in patients with primary fibromyalgia syndrome--a preliminary study. ( Hrycaj, P; Mennet, P; Müller, W; Stratz, T, 1996) |
| "1%) female patients with fibromyalgia completed an eight-week treatment period testing the combination of carisoprodol, paracetamol (acetaminophen) and caffeine versus placebo." | 9.06 | Treatment of fibromyalgia (fibrositis syndrome): a parallel double blind trial with carisoprodol, paracetamol and caffeine (Somadril comp) versus placebo. ( Abrahamsen, A; Førre, O; Kåss, E; Vaerøy, H, 1989) |
| "Because there is controversy regarding the efficacy of acetaminophen in rheumatic diseases and because apparently safer nonsteroidal antiinflammatory drugs (NSAIDs) are being produced, we surveyed rheumatic disease patients about their preferences for these agents to determine the degree to which one type of therapeutic agent is preferred over the other." | 7.70 | Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. ( Lane, N; Wolfe, F; Zhao, S, 2000) |
| "5 mg tramadol/325 mg acetaminophen) for the treatment of fibromyalgia pain." | 5.10 | Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study. ( Bennett, RM; Kamin, M; Karim, R; Rosenthal, N, 2003) |
| "The effect of the selective serotonin reuptake inhibitor citalopram was studied in a randomized, double-blind, placebo-controlled, 4-month trial in patients with the fibromyalgia syndrome (FMS) who all fulfilled the American College of Rheumatology criteria." | 5.09 | Citalopram in patients with fibromyalgia--a randomized, double-blind, placebo-controlled study. ( Anderberg, UM; Marteinsdottir, I; von Knorring, L, 2000) |
| "To study the efficacy of 5-hydroxytryptamine type 3 receptor (5-HT-3R) antagonist (ondansetron) vs paracetamol in primary fibromyalgia (FM) syndrome." | 5.08 | Pathogenetic aspects of responsiveness to ondansetron (5-hydroxytryptamine type 3 receptor antagonist) in patients with primary fibromyalgia syndrome--a preliminary study. ( Hrycaj, P; Mennet, P; Müller, W; Stratz, T, 1996) |
| "1%) female patients with fibromyalgia completed an eight-week treatment period testing the combination of carisoprodol, paracetamol (acetaminophen) and caffeine versus placebo." | 5.06 | Treatment of fibromyalgia (fibrositis syndrome): a parallel double blind trial with carisoprodol, paracetamol and caffeine (Somadril comp) versus placebo. ( Abrahamsen, A; Førre, O; Kåss, E; Vaerøy, H, 1989) |
| "Because there is controversy regarding the efficacy of acetaminophen in rheumatic diseases and because apparently safer nonsteroidal antiinflammatory drugs (NSAIDs) are being produced, we surveyed rheumatic disease patients about their preferences for these agents to determine the degree to which one type of therapeutic agent is preferred over the other." | 3.70 | Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. ( Lane, N; Wolfe, F; Zhao, S, 2000) |
| "Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide." | 2.58 | Combination pharmacotherapy for the treatment of fibromyalgia in adults. ( Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ, 2018) |
| "GR consumption improved mechanical and thermal allodynia and mechanical hyperalgesia and improved behavioural changes related to cognitive disturbances, anxiety, and depression." | 1.48 | Ginger rhizome enhances the anti-inflammatory and anti-nociceptive effects of paracetamol in an experimental mouse model of fibromyalgia. ( De la Puerta, R; Fernandez-Arche, A; Garcia-Gimenez, MD; Montserrat-de la Paz, S; Quilez, AM, 2018) |
| "Anxiety and depression are often also present." | 1.35 | Fibromyalgia: poorly understood; treatments are disappointing. ( , 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Valladales-Restrepo, LF | 1 |
| Oyuela-Gutiérrez, MC | 1 |
| Alzate-García, M | 1 |
| Osorio-Rodas, I | 1 |
| Quintero-Flórez, V | 1 |
| Restrepo-Muñoz, JF | 1 |
| Suárez-Cardona, JA | 1 |
| Barroso-Fernandes, ST | 1 |
| Machado-Alba, JE | 1 |
| Aster, HC | 1 |
| Evdokimov, D | 1 |
| Braun, A | 1 |
| Üçeyler, N | 1 |
| Sommer, C | 1 |
| Dhokia, M | 1 |
| Elander, J | 1 |
| Clements, K | 1 |
| Gilbert, P | 1 |
| Montserrat-de la Paz, S | 1 |
| Garcia-Gimenez, MD | 1 |
| Quilez, AM | 1 |
| De la Puerta, R | 1 |
| Fernandez-Arche, A | 1 |
| Thorpe, J | 1 |
| Shum, B | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Gilron, I | 1 |
| Meeus, M | 1 |
| Hermans, L | 1 |
| Ickmans, K | 1 |
| Struyf, F | 1 |
| Van Cauwenbergh, D | 1 |
| Bronckaerts, L | 1 |
| De Clerck, LS | 1 |
| Moorken, G | 1 |
| Hans, G | 1 |
| Grosemans, S | 1 |
| Nijs, J | 1 |
| Bennett, RM | 2 |
| Kamin, M | 1 |
| Karim, R | 1 |
| Rosenthal, N | 1 |
| Polańska, B | 1 |
| Basiewicz-Worsztynowicz, B | 1 |
| Lewandowicz-Uszyńska, A | 1 |
| Karnas-Kalemba, W | 1 |
| Jankowski, A | 1 |
| Tian, XP | 1 |
| Tang, FL | 1 |
| Schein, J | 1 |
| Kosinski, MR | 1 |
| Hewitt, DJ | 1 |
| Jordan, DM | 1 |
| Rosenthal, NR | 1 |
| Schmerz, F | 1 |
| Hrycaj, P | 1 |
| Stratz, T | 1 |
| Mennet, P | 1 |
| Müller, W | 1 |
| Wolfe, F | 1 |
| Zhao, S | 1 |
| Lane, N | 1 |
| Anderberg, UM | 1 |
| Marteinsdottir, I | 1 |
| von Knorring, L | 1 |
| Jajić, I | 1 |
| Delimar, N | 1 |
| Vaerøy, H | 1 |
| Abrahamsen, A | 1 |
| Førre, O | 1 |
| Kåss, E | 1 |
| McGuinness, BW | 1 |
| Lloyd-Jones, M | 1 |
| Fowler, PD | 1 |
| Wettreich, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Unraveling Impaired Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity Syndromes: a Series of Experiments Targeting Brain Neurotransmission[NCT01154647] | 70 participants (Anticipated) | Interventional | 2010-09-30 | Not yet recruiting | |||
| Evaluation of Spa Therapy in the Treatment of Fibromyalgia : a Randomized, Controlled, Open Multicenter Study[NCT02265029] | 220 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313] | 152 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | |||
| A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755] | 62 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetaminophen and Fibromyalgia
| Article | Year |
|---|---|
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; A | 2018 |
8 trials available for acetaminophen and Fibromyalgia
| Article | Year |
|---|---|
A randomized-controlled pilot trial of an online compassionate mind training intervention to help people with chronic pain avoid analgesic misuse.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Arthritis, Rheumatoid; Aspirin; Back Pain; Chr | 2020 |
Endogenous pain modulation in response to exercise in patients with rheumatoid arthritis, patients with chronic fatigue syndrome and comorbid fibromyalgia, and healthy controls: a double-blind randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Arthritis, Rheumatoid; Chronic Pain | 2015 |
Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug | 2003 |
Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug | 2003 |
Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug | 2003 |
Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug | 2003 |
Impact of fibromyalgia pain on health-related quality of life before and after treatment with tramadol/acetaminophen.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind M | 2005 |
Pathogenetic aspects of responsiveness to ondansetron (5-hydroxytryptamine type 3 receptor antagonist) in patients with primary fibromyalgia syndrome--a preliminary study.
Topics: Acetaminophen; Adult; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans; Male; M | 1996 |
Citalopram in patients with fibromyalgia--a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Activities of Daily Living; Adult; Analgesics, Non-Narcotic; Antidepressive Agents; C | 2000 |
Treatment of fibromyalgia (fibrositis syndrome): a parallel double blind trial with carisoprodol, paracetamol and caffeine (Somadril comp) versus placebo.
Topics: Acetaminophen; Adult; Aged; Caffeine; Carisoprodol; Clinical Trials as Topic; Double-Blind Method; F | 1989 |
A double-blind comparative trial of 'parazolidin' and paracetamol.
Topics: Acetaminophen; Adolescent; Adult; Aged; Back Pain; Clinical Trials as Topic; Elbow Joint; Female; Fi | 1969 |
10 other studies available for acetaminophen and Fibromyalgia
| Article | Year |
|---|---|
Treatment patterns in fibromyalgia including the use of opioids.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Cross-Sectional Studies; Female; Fibromyalgia; Human | 2023 |
Analgesic Medication in Fibromyalgia Patients: A Cross-Sectional Study.
Topics: Acetaminophen; Amitriptyline; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-St | 2022 |
Ginger rhizome enhances the anti-inflammatory and anti-nociceptive effects of paracetamol in an experimental mouse model of fibromyalgia.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Chronic Pain; Disease Models, Animal; Drug Synergi | 2018 |
Fibromyalgia: poorly understood; treatments are disappointing.
Topics: Acetaminophen; Acupuncture Therapy; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Ant | 2009 |
[Fibromyalgia syndrome: a case of a 16-year old girl: diagnosis, clinical and therapeutic problems].
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Electromyography; Fem | 2003 |
[Pay attention to fibromyalgia].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Biomedical Research; Fibromyalgia; Huma | 2004 |
[Many faces--one disease: fibromyalgia].
Topics: Acetaminophen; Aminopyridines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvuls | 2007 |
Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Fibromy | 2000 |
[Dorsilon in the treatment of fibrositis].
Topics: Acetaminophen; Adult; Drug Combinations; Female; Fibromyalgia; Humans; Male; Middle Aged; Oxazoles | 1978 |
[The association of paracetamol and phenylbutazone in rheumatology. Preliminary report].
Topics: Acetaminophen; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Female; Fibromyalgia; Humans; | 1966 |