Page last updated: 2024-10-22

acetaminophen and Fatty Liver with Encephalopathy

acetaminophen has been researched along with Fatty Liver with Encephalopathy in 32 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
" In 1980 s, the relevance of aspirin for Reye's syndrome became a problem, then acetaminophen came into use for various kinds of cases such as children, pregnant women and the elderly for pain management or alleviation of fever."3.83[Side Effects of Acetaminophen and their Management]. ( Saeki, S, 2016)
" Fever always occurred before their admission and aspirin (n = 12) or acetaminophen (n = 7) was prescribed."3.71[Severe Reye syndrome: report of 14 cases managed in a pediatric intensive care unit over 11 years]. ( Brivet, M; Chevret, L; Debray, D; Devictor, D; Durand, P; Fabre, M; Thabet, F, 2002)
" About 50% of patients given salicylate in full anti-inflammatory dosage develop minor abnormalities of liver function."2.37Liver damage with non-narcotic analgesics. ( Prescott, LF, 1986)
"Acetaminophen is an effective antipyretic and analgesic with few side effects that is toxic only in massive overdose."2.36Use of antipyretic analgesics in the pediatric patient. ( Gladtke, E, 1983)
"Cases of Reye's syndrome declined both in numbers (from a peak of 79 in 1983/4 to 19 in 1988/9) and in median age."1.28Trends in the incidence of Reye's syndrome and the use of aspirin. ( Banks, JH; Glasgow, JF; Hall, SM; Porter, JD; Robinson, PH, 1990)
"Using weanling mice of two different genetic strains we demonstrated a potentiation of the toxic effects of acetaminophen by prior infection with influenza B virus."1.27Potentiation of the toxic effects of acetaminophen in mice by concurrent infection with influenza B virus: a possible mechanism for human Reye's syndrome? ( Hudak, G; MacDonald, MG; McGrath, PP; McMartin, DN; Washington, GC, 1984)
"The parents of 106 children who had had Reye's syndrome and those of 185 comparison children who had febrile illnesses were interviewed in order to compare preadmission medication exposure rates in the two groups."1.27Preadmission antipyretics in Reye's syndrome. ( Glasgow, JF; Hall, SM; Hancock, P; Plaster, PA, 1988)
"The number of cases of Reye syndrome reported annually to the Centers for Disease Control declined markedly between 1980 and 1985."1.27National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985. ( Arrowsmith, JB; Faich, GA; Kennedy, DL; Kuritsky, JN, 1987)
" In Australia, the pediatric usage of aspirin has been extremely low for the past 25 years (less than 1% of total dosage units sold), with paracetamol (acetaminophen) dominating the pediatric analgesic and antipyretic market."1.27A catch in the Reye. ( Gillis, J; Kilham, HA; Orlowski, JP, 1987)
"Patients with Reye's syndrome (RS) whose degree of severity was classified as stage 0 (alert and awake) were compared with patients with a severity classification of stage 1 or greater."1.27Reye's syndrome. An epidemiologic analysis of mild disease. ( Campbell, RJ; Hall, LJ; Halpin, TJ; Holtzhauer, FJ, 1986)
"The incidence of Reye syndrome has been decreasing in Michigan, perhaps as a result of decreased aspirin use among children."1.27Decreasing trends in Reye syndrome and aspirin use in Michigan, 1979 to 1984. ( Hall, WN; McGee, H; Monto, AS; Remington, PL; Rowley, D, 1986)
"Fever was measured with a thermometer in 114 ill children, 103 of whom had at least one measured temperature of 37."1.27Antipyretic use among children during the 1983 influenza season. ( Brandenburg, N; Glezen, WP; Gustafson, TL; Johnson, CC; Taylor, JP, 1985)
"Thirty patients with Reye's syndrome, whose diagnosis was confirmed by an expert panel, and 145 controls were matched for age, race (black or not black), and antecedent illness (respiratory infection, chickenpox, or diarrhea) and selected from the same hospital, emergency room, or school, or identified by random digit dialing."1.27Public Health Service study on Reye's syndrome and medications. Report of the pilot phase. ( Barrett, MJ; Bregman, D; Burlington, DB; Drage, JS; Fairweather, WR; Gunn, WJ; Hurwitz, ES; Kaslow, RA; LaMontagne, JR; Schonberger, LB, 1985)
" In 87% of the cases receiving aspirin, their maximum daily dosage did not exceed recommended levels, but their doses were higher than those of controls receiving aspirin."1.26Reye's syndrome and medication use. ( Campbell, RJ; Correa-VillaseƱor, A; Hall, LJ; Halpin, TJ; Holtzhauer, FJ; Hurwitz, ES; Lanese, R; Rice, J, 1982)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199024 (75.00)18.7374
1990's2 (6.25)18.2507
2000's2 (6.25)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dinakaran, D1
Sergi, CM1
Saeki, S1
Johnson, CC2
Ownby, DR1
Aronowitz, RA1
Aronoff, DM1
Gladtke, E1
Addy, DP1
Kang, ES1
Olson, G1
Jabbour, JT1
Solomon, SS1
Heimberg, M1
Sabesin, S1
Griffith, JF1
MacDonald, MG1
McGrath, PP1
McMartin, DN1
Washington, GC1
Hudak, G1
Halpin, TJ2
Holtzhauer, FJ2
Campbell, RJ2
Hall, LJ2
Correa-VillaseƱor, A1
Lanese, R1
Rice, J1
Hurwitz, ES2
Eden, AN1
Sutherland, LR1
Muller, P1
Lewis, DR1
Thabet, F1
Durand, P1
Chevret, L1
Fabre, M1
Debray, D1
Brivet, M1
Devictor, D1
Little, JA1
Gutknecht, J1
Porter, JD1
Robinson, PH1
Glasgow, JF2
Banks, JH1
Hall, SM2
Cugurra, F1
Holmes, A1
Davidson, LE1
Guignard, JP1
Gouyon, JB1
Geubelle, F1
Plaster, PA1
Hancock, P1
Prescott, LF1
Arrowsmith, JB1
Kennedy, DL1
Kuritsky, JN1
Faich, GA1
Orlowski, JP1
Gillis, J1
Kilham, HA1
Banco, L1
Gray, JD1
Blaschke, TF1
Peterson, RG1
Remington, PL1
Rowley, D1
McGee, H1
Hall, WN1
Monto, AS1
Rahwan, GL1
Rahwan, RG1
Taylor, JP1
Gustafson, TL1
Brandenburg, N1
Glezen, WP1
Barrett, MJ1
Bregman, D1
Gunn, WJ1
Schonberger, LB1
Fairweather, WR1
Drage, JS1
LaMontagne, JR1
Kaslow, RA1
Burlington, DB1

Reviews

5 reviews available for acetaminophen and Fatty Liver with Encephalopathy

ArticleYear
Co-ingestion of aspirin and acetaminophen promoting fulminant liver failure: A critical review of Reye syndrome in the current perspective at the dawn of the 21st century.
    Clinical and experimental pharmacology & physiology, 2018, Volume: 45, Issue:2

    Topics: Acetaminophen; Aspirin; Child; Drug Interactions; Drug Therapy, Combination; Humans; Liver Failure,

2018
Use of antipyretic analgesics in the pediatric patient.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adolescent; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemic

1983
[Reye's syndrome and aspirin].
    Revue medicale de Liege, 1988, Jan-01, Volume: 43, Issue:1

    Topics: Acetaminophen; Aspirin; Chickenpox; Diagnosis, Differential; Humans; Influenza, Human; Reye Syndrome

1988
Liver damage with non-narcotic analgesics.
    Medical toxicology, 1986, Volume: 1 Suppl 1

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver

1986
Antipyretics and analgesics in children.
    Developmental pharmacology and therapeutics, 1985, Volume: 8, Issue:1

    Topics: Acetaminophen; Acid-Base Equilibrium; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child

1985

Other Studies

27 other studies available for acetaminophen and Fatty Liver with Encephalopathy

ArticleYear
[Side Effects of Acetaminophen and their Management].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:7

    Topics: Acetaminophen; Aspirin; Chronic Pain; Cyclooxygenase 1; Fever; Humans; Pain Management; Reye Syndrom

2016
Have the efforts to prevent aspirin-related Reye's syndrome fuelled an increase in asthma?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; H

2011
The social and economic influences on medication use and misuse.
    Journal of general internal medicine, 2012, Volume: 27, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Drug-Related Side E

2012
Aspirin and Reye's syndrome: discovery of aspirin and paracetamol.
    Drug safety, 2002, Volume: 25, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; History,

2002
Cold comfort for hot children.
    British medical journal (Clinical research ed.), 1983, Apr-09, Volume: 286, Issue:6372

    Topics: Acetaminophen; Aspirin; Child; Child, Preschool; Fever; Humans; Infant; Reye Syndrome

1983
Development of encephalopathic features similar to Reye syndrome in rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:19

    Topics: Acetaminophen; Animals; Aspirin; Disease Models, Animal; Encephalitis; Fatty Acids, Nonesterified; F

1984
Potentiation of the toxic effects of acetaminophen in mice by concurrent infection with influenza B virus: a possible mechanism for human Reye's syndrome?
    Pediatric research, 1984, Volume: 18, Issue:2

    Topics: Acetaminophen; Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Ind

1984
Reye's syndrome and medication use.
    JAMA, 1982, Aug-13, Volume: 248, Issue:6

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Humans; I

1982
Why not use acetaminophen for fever?
    Pediatrics, 1982, Volume: 70, Issue:4

    Topics: Acetaminophen; Child; Fever; Humans; Reye Syndrome

1982
Massive cerebral edema associated with fulminant hepatic failure in acetaminophen overdose: possible role of cranial decompression.
    The American journal of gastroenterology, 1981, Volume: 76, Issue:5

    Topics: Acetaminophen; Adolescent; Brain Edema; Chemical and Drug Induced Liver Injury; Female; Humans; Live

1981
[Severe Reye syndrome: report of 14 cases managed in a pediatric intensive care unit over 11 years].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:6

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Edema; Child; Child, Preschoo

2002
Acetaminophen and Reye's syndrome.
    Pediatrics, 1976, Volume: 58, Issue:6

    Topics: Acetaminophen; Child; Diagnosis, Differential; Humans; Reye Syndrome

1976
Aspirin, acetaminophen and proton transport through phospholipid bilayers and mitochondrial membranes.
    Molecular and cellular biochemistry, 1992, Sep-08, Volume: 114, Issue:1-2

    Topics: Acetaminophen; Animals; Anions; Aspirin; Biological Transport; Humans; Hydrogen-Ion Concentration; I

1992
Trends in the incidence of Reye's syndrome and the use of aspirin.
    Archives of disease in childhood, 1990, Volume: 65, Issue:8

    Topics: Acetaminophen; Aspirin; Child; Child, Preschool; Female; Fever; Humans; Incidence; Infant; Male; Rey

1990
[XXVIII. Antipyretic and antineuralgic agents for grown-ups and little-ones].
    La Clinica terapeutica, 1989, Dec-15, Volume: 131, Issue:5

    Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Infant, Ne

1989
Reye's syndrome and analgesic choice in dentistry.
    British dental journal, 1989, Nov-25, Volume: 167, Issue:10

    Topics: Acetaminophen; Aspirin; Attitude; Child; Child, Preschool; Female; Health Education; Humans; Infant;

1989
[Reye's syndrome and salicylates].
    Revue medicale de la Suisse romande, 1988, Volume: 108, Issue:12

    Topics: Acetaminophen; Adolescent; Aspirin; Child; Humans; Reye Syndrome; Salicylates; Virus Diseases

1988
Preadmission antipyretics in Reye's syndrome.
    Archives of disease in childhood, 1988, Volume: 63, Issue:7

    Topics: Acetaminophen; Adolescent; Aspirin; Child; Child, Preschool; Fever; Hospitalization; Humans; Infant;

1988
National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985.
    Pediatrics, 1987, Volume: 79, Issue:6

    Topics: Acetaminophen; Adult; Aspirin; Child; Drug Utilization; Humans; Middle Aged; Reye Syndrome; United S

1987
A catch in the Reye.
    Pediatrics, 1987, Volume: 80, Issue:5

    Topics: Acetaminophen; Aspirin; Australia; Child; Child, Preschool; Female; Humans; Infant; Male; Retrospect

1987
Reye's syndrome. An epidemiologic analysis of mild disease.
    American journal of diseases of children (1960), 1986, Volume: 140, Issue:12

    Topics: Acetaminophen; Ammonia; Aspirin; Bilirubin; Female; Humans; Male; Reye Syndrome

1986
Use of aspirin and Reye's syndrome.
    American journal of diseases of children (1960), 1987, Volume: 141, Issue:3

    Topics: Acetaminophen; Aspirin; Child; Fever; Humans; Reye Syndrome

1987
Fever: to treat or not to treat.
    Rational drug therapy, 1985, Volume: 19, Issue:12

    Topics: Acetaminophen; Aspirin; Child; Fever; Humans; Ibuprofen; Interleukin-1; Reye Syndrome

1985
Decreasing trends in Reye syndrome and aspirin use in Michigan, 1979 to 1984.
    Pediatrics, 1986, Volume: 77, Issue:1

    Topics: Acetaminophen; Aspirin; Child; Common Cold; Fever; Humans; Michigan; Reye Syndrome

1986
Aspirin and Reye's syndrome: the change in prescribing habits of health professionals.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:2

    Topics: Acetaminophen; Aspirin; Child; Drug Prescriptions; Drug Utilization; Humans; Ohio; Reye Syndrome; Su

1986
Antipyretic use among children during the 1983 influenza season.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Aspirin; Chickenpox; Child; Child, Preschool; Female; Fever; Healt

1985
Public Health Service study on Reye's syndrome and medications. Report of the pilot phase.
    The New England journal of medicine, 1985, Oct-03, Volume: 313, Issue:14

    Topics: Acetaminophen; Adolescent; Chickenpox; Child; Child, Preschool; Emergencies; Female; Humans; Infant;

1985