acetaminophen has been researched along with Erythema in 11 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At 2 months of age, 145 infants were randomized to receive either a two-component acellular pertussis vaccine [lymphocytosis-promoting factor (LPF)/filamentous hemagglutinin (FHA)] or standard whole-cell pertussis vaccine, each combined with diphtheria-tetanus toxoids, as their primary immunization series." | 2.67 | Primary immunization series for infants: comparison of two-component acellular and standard whole-cell pertussis vaccines combined with diphtheria-tetanus toxoids. ( Andrew, M; Feldman, S; Jones, L; Lamb, D; Meschievitz, C; Moffitt, JE; Perry, CS, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitsui, S | 1 |
| Katayama, C | 1 |
| Aoyama, Y | 1 |
| Mizukawa, Y | 1 |
| Kuyama, M | 1 |
| Kawakami, Y | 1 |
| Ladizinski, B | 1 |
| Sankey, C | 1 |
| Giles, FJ | 1 |
| Cortes, JE | 1 |
| Halliburton, TA | 1 |
| Mallard, SJ | 1 |
| Estey, EH | 1 |
| Waddelow, TA | 1 |
| Lim, JT | 1 |
| Jackson, LA | 1 |
| Dunstan, M | 1 |
| Starkovich, P | 1 |
| Dunn, J | 1 |
| Yu, O | 1 |
| Nelson, JC | 1 |
| Rees, T | 1 |
| Zavitkovsky, A | 1 |
| Filipe, PL | 1 |
| Freitas, JP | 1 |
| de Castro, JC | 1 |
| Silva, R | 1 |
| Rodrigo, FG | 1 |
| Feldman, S | 1 |
| Perry, CS | 1 |
| Andrew, M | 1 |
| Jones, L | 1 |
| Moffitt, JE | 1 |
| Lamb, D | 1 |
| Meschievitz, C | 1 |
| Kawada, A | 1 |
| Hiruma, M | 1 |
| Noguchi, H | 1 |
| Ishibashi, A | 1 |
| Feyen, H | 1 |
| Nissen, H | 1 |
| Hiemeyer, V | 1 |
| Forster, C | 1 |
| Magerl, W | 1 |
| Beck, A | 1 |
| Geisslinger, G | 1 |
| Gall, T | 1 |
| Brune, K | 1 |
| Handwerker, HO | 1 |
| Long, SS | 1 |
| Deforest, A | 1 |
| Smith, DG | 1 |
| Lazaro, C | 1 |
| Wassilak, GF | 1 |
| Lyell, A | 1 |
| Alexander, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation: the NEED LESS PAIN Study"[NCT02807623] | 300 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Swelling at vaccination site (NCT02807623)
Timeframe: baseline, 48-72 hours, and 21- 28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
Reddening of the skin at vaccination site reported as the total number of participants with erythema over the duration of the study. (NCT02807623)
Timeframe: baseline, 48- 72 hours, 21-28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
A Lactate meter was used to test the exercise group for lactate readings. Two lactate tests was performed for the exercise group at Visit 1, both pre and post Influenza vaccination. The first lactate reading was taken after the blood draw.The second lactate reading was obtained from a fingerstick from the hand opposite to the vaccination arm, ideally within 3-8 minutes after the study subject completes pushups. (NCT02807623)
Timeframe: Immediately prior to Influenza vaccine and 3-8 minutes after Influenza vaccine was administered and after push-ups were completed.
| Intervention | mmol/L (Mean) | |
|---|---|---|
| Lactate before pushups | Lactate after pushups | |
| Compound Exercise of Push-ups | 1.51 | 7.69 |
Level of Pain will be measured by validated pain scale, using a scale of 0 ( best, no pain) to 10 (worst, as bad as imaginable, completely interferes). (NCT02807623)
Timeframe: baseline, 48-72 hours and at 21-28 days ( 3 points )
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | |
| Compound Exercise of Push-ups | .14 | .19 | .13 |
| Ibuprofen | .39 | .56 | .28 |
| Placebo | .19 | .22 | .06 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 214.80 | 345.09 |
| Ibuprofen | 171.00 | 239.25 |
| Placebo | 216.75 | 343.03 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 149.22 | 232.58 |
| Ibuprofen | 177.78 | 243.13 |
| Placebo | 221.09 | 296.66 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 26.00 | 41.02 |
| Ibuprofen | 17.41 | 25.47 |
| Placebo | 26.09 | 34.09 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 32.89 | 49.07 |
| Ibuprofen | 40.16 | 47.34 |
| Placebo | 36.69 | 44.78 |
6 trials available for acetaminophen and Erythema
| Article | Year |
|---|---|
Intravenous corticosteroids to reduce gemtuzumab ozogamicin infusion reactions.
Topics: Acetaminophen; Adult; Aminoglycosides; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflamm | 2003 |
Prophylaxis with acetaminophen or ibuprofen for prevention of local reactions to the fifth diphtheria-tetanus toxoids-acellular pertussis vaccination: a randomized, controlled trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Pres | 2006 |
Primary immunization series for infants: comparison of two-component acellular and standard whole-cell pertussis vaccines combined with diphtheria-tetanus toxoids.
Topics: Academic Medical Centers; Acetaminophen; Antibody Formation; Diphtheria-Tetanus-Pertussis Vaccine; D | 1993 |
[Studies on the influence of pentosanepolysulfate and a combination of pentosanepolysulfate, metamizol and paracetamol on inflammatory liability (author's transl)].
Topics: Acetaminophen; Adult; Aminopyrine; Anti-Inflammatory Agents; Clinical Trials as Topic; Dipyrone; Dos | 1975 |
Differential effects of dipyrone, ibuprofen, and paracetamol on experimentally induced pain in man.
Topics: Acetaminophen; Adult; Analgesia; Dipyrone; Erythema; Female; Humans; Ibuprofen; Male; Muscle, Smooth | 1992 |
Longitudinal study of adverse reactions following diphtheria-tetanus-pertussis vaccine in infancy.
Topics: Acetaminophen; Age Factors; Antibody Formation; Diphtheria-Tetanus-Pertussis Vaccine; Erythema; Feve | 1990 |
5 other studies available for acetaminophen and Erythema
| Article | Year |
|---|---|
Local desensitization and progression of multiple fixed drug eruption.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Disease Progression; Drug Eruptions; Erythema; Female; Huma | 2018 |
A topical matter: toxic epidermal necrolysis.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents; Anticonvulsants; Antiemetics; Antineopl | 2014 |
Drug eruption induced by acetaminophen in infectious mononucleosis.
Topics: Acetaminophen; Adult; Drug Eruptions; Erythema; Humans; Infectious Mononucleosis; Male; Pruritus; Pu | 1995 |
Fixed drug eruption induced by acetaminophen in a 12-year-old girl.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Drug Eruptions; Erythema; Female; Humans; Hyperpigme | 1996 |
Paracetamol overdose.
Topics: Acetaminophen; Adult; Blood Sedimentation; Cell Migration Inhibition; Dysmenorrhea; Erythema; Female | 1971 |