Page last updated: 2024-10-22

acetaminophen and Encephalopathy, Toxic

acetaminophen has been researched along with Encephalopathy, Toxic in 11 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"The objectives of this study were to compare the incidence, onset, duration and pain scores of transient neurologic symptoms (TNS) with 1% versus 5% hyperbaric lidocaine in spinal anesthesia for short urological procedures in a large prospective study."5.10Prospective study on incidence and functional impact of transient neurologic symptoms associated with 1% versus 5% hyperbaric lidocaine in short urologic procedures. ( Bremang, J; Chung, F; Friedlander, M; Mezei, G; Streiner, D; Tong, D; Wong, J, 2003)
"Sepsis and acute liver failure are associated with severe endogenous intoxication."1.72Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study. ( Hayden, MR; Shulyatnikova, T; Tumanskyi, V, 2022)
" The aim of this study was to characterize the direct toxic effects of APAP in different regions of the brain and on behavior in rats where the magnitude of hepatotoxicity produced is not associated with ALF."1.51Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation. ( Bisagno, V; De Fino, F; Di Carlo, MB; Ghanem, CI; Gómez, G; Manautou, JE; Martínez, SA; Pérez, MJ; Scazziota, A; Vigo, MB, 2019)
" However, recent findings in both humans and rodents suggest a link between developmental exposure to AAP and adverse neurobehavioral effects later in life."1.48A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol). ( Fredriksson, A; Fredriksson, R; Gordh, T; Hallgren, S; Philippot, G; Viberg, H, 2018)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's3 (27.27)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Shulyatnikova, T3
Tumanskyi, V3
Hayden, MR3
Vigo, MB1
Pérez, MJ1
De Fino, F1
Gómez, G1
Martínez, SA1
Bisagno, V1
Di Carlo, MB1
Scazziota, A1
Manautou, JE1
Ghanem, CI1
Philippot, G2
Hellsten, SV1
Viberg, H2
Fredriksson, R2
Beghin, M1
Schmitz, M1
Betoulle, S1
Palluel, O1
Baekelandt, S1
Mandiki, SNM1
Gillet, E1
Nott, K1
Porcher, JM1
Robert, C1
Ronkart, S1
Kestemont, P1
Hallgren, S1
Gordh, T1
Fredriksson, A1
da Silva, MH1
da Rosa, EJ1
de Carvalho, NR1
Dobrachinski, F1
da Rocha, JB1
Mauriz, JL1
González-Gallego, J1
Soares, FA1
Tong, D1
Wong, J1
Chung, F1
Friedlander, M1
Bremang, J1
Mezei, G1
Streiner, D1
Maharaj, DS2
Saravanan, KS1
Maharaj, H2
Mohanakumar, KP1
Daya, S2
Dabos, KJ1
Newsome, PN1
Parkinson, JA1
Davidson, JS1
Sadler, IH1
Plevris, JN1
Hayes, PC1
Hari, P1
Jain, Y1
Kabra, SK1

Trials

1 trial available for acetaminophen and Encephalopathy, Toxic

ArticleYear
Prospective study on incidence and functional impact of transient neurologic symptoms associated with 1% versus 5% hyperbaric lidocaine in short urologic procedures.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics,

2003

Other Studies

10 other studies available for acetaminophen and Encephalopathy, Toxic

ArticleYear
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Reactive Microgliosis in Sepsis-Associated and Acute Hepatic Encephalopathies: An Ultrastructural Study.
    International journal of molecular sciences, 2022, Nov-21, Volume: 23, Issue:22

    Topics: Acetaminophen; Animals; Delirium; Hepatic Encephalopathy; Hypertrophy; Liver Failure; Neurotoxicity

2022
Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation.
    Biochemical pharmacology, 2019, Volume: 170

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultur

2019
Evaluation of the dentate gyrus in adult mice exposed to acetaminophen (paracetamol) on postnatal day 10.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2021, Volume: 81, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Cell Differentiation; Cell Movem

2021
Integrated multi-biomarker responses of juvenile rainbow trout (Oncorhynchus mykiss) to an environmentally relevant pharmaceutical mixture.
    Ecotoxicology and environmental safety, 2021, Sep-15, Volume: 221

    Topics: Acetaminophen; Animals; Belgium; Biomarkers; Brain; Carbamazepine; Diclofenac; Irbesartan; Liver; Ly

2021
A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol).
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 11-01, Volume: 166, Issue:1

    Topics: Acetaminophen; Animals; Animals, Newborn; Behavior, Animal; Brain; Cannabinoids; Drug Synergism; Mal

2018
Acute brain damage induced by acetaminophen in mice: effect of diphenyl diselenide on oxidative stress and mitochondrial dysfunction.
    Neurotoxicity research, 2012, Volume: 21, Issue:3

    Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antioxidants;

2012
Acetaminophen and aspirin inhibit superoxide anion generation and lipid peroxidation, and protect against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
    Neurochemistry international, 2004, Volume: 44, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetaminophen; Analgesics

2004
A biochemical prognostic model of outcome in paracetamol-induced acute liver injury.
    Transplantation, 2005, Dec-27, Volume: 80, Issue:12

    Topics: Acetaminophen; Adult; Blood Chemical Analysis; Cohort Studies; Female; Hemoglobins; Humans; Liver; L

2005
Acetylsalicylic acid and acetaminophen protect against oxidative neurotoxicity.
    Metabolic brain disease, 2006, Volume: 21, Issue:2-3

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflam

2006
Fatal encephalopathy and renal failure caused by diethylene glycol poisoning.
    Journal of tropical pediatrics, 2006, Volume: 52, Issue:6

    Topics: Acetaminophen; Acute Kidney Injury; Child, Preschool; Drug Contamination; Ethylene Glycols; Fatal Ou

2006