acetaminophen and Emesis, Postoperative studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

Excerpt	Relevance	Reference
"This randomized trial evaluated the effect of intravenous patient-controlled analgesia (IV-PCA) based on fentanyl mixed with either propacetamol or an equivalent volume of normal saline on postoperative nausea and vomiting (PONV) in highly susceptible patients undergoing spinal surgery."	9.22	Patient-controlled Analgesia With Propacetamol-Fentanyl Mixture for Prevention of Postoperative Nausea and Vomiting in High-risk Patients Undergoing Spine Surgery: A Randomized Controlled Trial. ( Kim, EJ; Kwak, YL; Lee, SR; Shim, JK; Soh, S; Song, JW, 2016)
"Prophylactic oral dolasetron and ondansetron were effective in reducing postoperative nausea and vomiting in children."	9.10	Comparison of oral dolasetron and ondansetron in the prophylaxis of postoperative nausea and vomiting in children. ( Karamanlioglu, B; Memis, D; Süt, N; Turan, A, 2003)
"Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery."	9.10	Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002)
"Rectal acetaminophen (Ac) is often administered prophylactically at anesthesia induction for postoperative pain management in small children and is thought to have an opioid-sparing effect."	9.09	Prophylactically-administered rectal acetaminophen does not reduce postoperative opioid requirements in infants and small children undergoing elective cleft palate repair. ( Behne, M; Bremerich, DH; Heimann, K; Kessler, P; Neidhart, G, 2001)
"To determine the efficacy of oral granisetron in preventing postoperative vomiting (POV) following strabismus repair in children."	9.09	Oral granisetron for strabismus surgery in children. ( D'Errico, CC; Lauder, GR; Munro, HM; Tait, AR; Voepel-Lewis, T; Wagner, DS, 1999)
"The aim of this study was to assess the effect of scheduled intravenous acetaminophen (SIVA) on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic gynecologic surgery (LGS)."	7.96	Effect of scheduled intravenous acetaminophen on postoperative nausea and vomiting in patients undergoing laparoscopic gynecologic surgery. ( Kamada, T; Nagahuchi, M; Sato, T; Suga, K; Taniguchi, H; Ueda, T; Yamamoto, T, 2020)
" Pain at rest/motion (based on pain visual analog scale (VAS) score), rescue analgesia consumption, satisfaction level and adverse events were assessed after AKS."	7.01	Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. ( Di, J; Liu, J; Xing, E; Zhang, Y, 2021)
"PONV was assessed in recovery and 24 hours after surgery in the ward."	7.01	Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. ( Aghabagheri, M; Khajavi, MR; Najjari, K; Pourfakhr, P; Talebpour, M; Zabihi Mahmoudabadi, H, 2021)
"Acetaminophen does not inhibit this synthesis at the inflammatory site."	6.55	Pharmacology of Acetaminophen, Nonsteroidal Antiinflammatory Drugs, and Steroid Medications: Implications for Anesthesia or Unique Associated Risks. ( Candido, KD; Knezevic, NN; Perozo, OJ, 2017)
"Opioids are a key risk factor for postoperative nausea and vomiting (PONV)."	6.49	Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. ( Apfel, CC; Hornuss, C; Pergolizzi, J; Souza, K; Turan, A, 2013)
"This randomized trial evaluated the effect of intravenous patient-controlled analgesia (IV-PCA) based on fentanyl mixed with either propacetamol or an equivalent volume of normal saline on postoperative nausea and vomiting (PONV) in highly susceptible patients undergoing spinal surgery."	5.22	Patient-controlled Analgesia With Propacetamol-Fentanyl Mixture for Prevention of Postoperative Nausea and Vomiting in High-risk Patients Undergoing Spine Surgery: A Randomized Controlled Trial. ( Kim, EJ; Kwak, YL; Lee, SR; Shim, JK; Soh, S; Song, JW, 2016)
"Investigators from Bristol described a fentanyl- and diclofenac-based analgesic technique for tonsillectomy with low postoperative nausea and vomiting rates and low pain scores."	5.15	A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy*. ( Bagshaw, O; Rawlinson, E; Skone, R; Thillaivasan, A; Walker, A, 2011)
"Oral dexamethasone combined with paracetamol significantly reduced total oxycodone consumption following surgical correction of hallux valgus."	5.14	Dexamethasone decreases oxycodone consumption following osteotomy of the first metatarsal bone: a randomized controlled trial in day surgery. ( Hynynen, MJ; Kalso, E; Kontinen, VK; Mattila, K, 2010)
"In the sub-Tenon's bupivacaine group, there was a significant reduction in the perioperative opioid use and a reduction in the frequency of bradycardia and hypertensive episodes, defined as a rise > 25% of baseline for a duration of > 3 min."	5.10	Sub-Tenon's block reduces both intraoperative and postoperative analgesia requirement in vitreo-retinal surgery under general anaesthesia. ( Farmery, AD; Rahman, R; Rosen, P; Shlugman, D, 2003)
"Prophylactic oral dolasetron and ondansetron were effective in reducing postoperative nausea and vomiting in children."	5.10	Comparison of oral dolasetron and ondansetron in the prophylaxis of postoperative nausea and vomiting in children. ( Karamanlioglu, B; Memis, D; Süt, N; Turan, A, 2003)
"Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery."	5.10	Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002)
"To determine the efficacy of oral granisetron in preventing postoperative vomiting (POV) following strabismus repair in children."	5.09	Oral granisetron for strabismus surgery in children. ( D'Errico, CC; Lauder, GR; Munro, HM; Tait, AR; Voepel-Lewis, T; Wagner, DS, 1999)
"Rectal acetaminophen (Ac) is often administered prophylactically at anesthesia induction for postoperative pain management in small children and is thought to have an opioid-sparing effect."	5.09	Prophylactically-administered rectal acetaminophen does not reduce postoperative opioid requirements in infants and small children undergoing elective cleft palate repair. ( Behne, M; Bremerich, DH; Heimann, K; Kessler, P; Neidhart, G, 2001)
" Pain at rest, during cough, and mobilization, request for supplementary morphine, and time to first postoperative flatus, was reduced in patients receiving 24-h postoperative epidural anaesthesia, compared with the two other groups."	5.09	Effect of peri- and postoperative epidural anaesthesia on pain and gastrointestinal function after abdominal hysterectomy. ( Andreasson, B; Dahl, JB; Dirks, J; Fomsgaard, JS; Jørgensen, H; Wetterslev, J, 2001)
" Ketamine was shown to increased postoperative nausea and vomiting."	5.05	Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review. ( Lin, H; Nguyen, BK; Pashkova, AA; Pinto, J; Quan, D; Stathakios, J; Svider, PF, 2020)
"The aim of this study was to assess the effect of scheduled intravenous acetaminophen (SIVA) on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic gynecologic surgery (LGS)."	3.96	Effect of scheduled intravenous acetaminophen on postoperative nausea and vomiting in patients undergoing laparoscopic gynecologic surgery. ( Kamada, T; Nagahuchi, M; Sato, T; Suga, K; Taniguchi, H; Ueda, T; Yamamoto, T, 2020)
" Our anesthetic protocol for strabismus surgery included postoperative nausea and vomiting prevention using dexamethasone and ondansetron."	3.91	Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery. ( Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M, 2019)
" Pain at rest/motion (based on pain visual analog scale (VAS) score), rescue analgesia consumption, satisfaction level and adverse events were assessed after AKS."	3.01	Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. ( Di, J; Liu, J; Xing, E; Zhang, Y, 2021)
"PONV was assessed in recovery and 24 hours after surgery in the ward."	3.01	Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. ( Aghabagheri, M; Khajavi, MR; Najjari, K; Pourfakhr, P; Talebpour, M; Zabihi Mahmoudabadi, H, 2021)
"I."	2.87	Randomized trial of oral versus intravenous acetaminophen for postoperative pain control. ( Bradford, LM; Garman, CD; Gregg, RW; Hickman, SR; Lukens, DW; Mathieson, KM, 2018)
"Celecoxib usage was associated with significantly more vomiting and did not reduce narcotic analgesia requirement post-tonsillectomy."	2.84	Is celecoxib a useful adjunct in the treatment of post-tonsillectomy pain in the adult population? A randomised, double-blind, placebo-controlled study. ( De Silva, N; Diamantaras, D; Mahanta, V; Ng, TT; Priestley, J; Redman, J, 2017)
"Eight studies assessed postoperative pain, whereas two assessed postoperative nausea and vomiting."	2.82	Comparison of intravenous and oral administration of acetaminophen in adults undergoing general anesthesia. ( Cao, Q; Dong, H; Fan, C; Meng, H; Yuan, R; Zhang, S, 2022)
"A total of 50 children undergoing craniosynostosis corrections were prospectively randomized to a control group given only oral ibuprofen (10 mg/kg) and acetaminophen (15 mg/kg), or a treatment group given only intravenous ketorolac (0."	2.80	A Randomized Controlled Trial of Oral Versus Intravenous Administration of a Nonnarcotic Analgesia Protocol Following Pediatric Craniosynostosis Corrections on Nausea and Vomiting Rates. ( Dimas, V; Ditthakasem, K; Fearon, JA; Herbert, MA, 2015)
"Nicotine treatment was associated with a highly significant decrease in pain reported during the 5 days after TM surgery."	2.76	Nicotine nasal spray as an adjuvant analgesic for third molar surgery. ( Afzali, P; Akkara, J; Alfi, DM; Conell-Price, J; Eisig, SB; Flood, P; Olson, L; Yagoubian, B; Yeh, J, 2011)
"The frequency of postoperative nausea and vomiting also was noted."	2.76	The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children. ( Baltaci, B; Başar, H; Takmaz, SA; Uysal, HY; Yaman, F, 2011)
"Postoperative pain was treated with patient-controlled intravenous hydromorphone 0."	2.76	The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy. ( Lee, J; Lee, YK; Moon, DE; Moon, YE, 2011)
"The extent of mechanical dynamic hyperalgesia on the middle line perpendicular to the wound was considered the primary endpoint."	2.76	Target-controlled dosing of remifentanil during cardiac surgery reduces postoperative hyperalgesia. ( Cahana, A; Calderon, J; Janvier, G; Jelacic, S; Mehta, S; Picard, W; Pouquet, O; Richebé, P; Rivat, C, 2011)
"Of 200 consecutive breast cancer patients, 191 received the full package."	2.75	Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2010)
"General anaesthesia was performed."	2.74	Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. ( Dahl, JB; Dierking, G; Fomsgaard, JS; Hilsted, KL; Lech, K; Lose, G; Mathiesen, O; Rasmussen, ML, 2009)
"Postoperative pain was evaluated by visual analog scale, and it was measured at rest and during a deep breath."	2.73	Intravenous paracetamol as adjunctive treatment for postoperative pain after cardiac surgery: a double blind randomized controlled trial. ( Bacchi-Reggiani, L; Cattabriga, I; Di Bartolomeo, R; Grillone, G; Lamazza, G; Pacini, D; Talarico, F, 2007)
"ESS is associated with significant postoperative pain."	2.72	Acetaminophen is highly effective in pain treatment after endoscopic sinus surgery. ( Kemppainen, T; Kokki, H; Nuutinen, J; Seppä, J; Tuomilehto, H, 2006)
"Rofecoxib was also more effective than celecoxib in reducing pain and improving patient satisfaction after otolaryngologic surgery."	2.71	Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. ( Issioui, T; Klein, KW; Watcha, MF; White, PF, 2003)
"Incidence of postoperative nausea and vomiting (PONV) was noted."	2.71	Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. ( Jakobsson, J; Owall, A; Pettersson, PH, 2005)
" The present prospective, placebo-controlled and double-blind study aimed to evaluate the analgesic efficacy of diclofenac, a non-steroid anti-inflammatory drug (NSAID), in combination with paracetamol and opioids."	2.71	Analgesic efficacy of diclofenac in combination with morphine and paracetamol after mastectomy and immediate breast reconstruction. ( Legeby, M; Olofsson, C; Sandelin, K; Wickman, M, 2005)
"Finally, patient satisfaction with postoperative pain control was significantly higher in the FT group."	2.71	Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. ( Cadeddu, JA; Duchene, D; Johnson, DB; Recart, A; Thomas, T; White, PF, 2005)
" Acetaminophen is not absorbed from the stomach but is rapidly absorbed from the small intestine, and the rate of gastric emptying therefore determines the rate of absorption of acetaminophen administered into the stomach."	2.70	Perioperative gastric emptying is not a predictor of early postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. ( Klockhoff, H; Larsson, LG; Lövqvist, A; Näslund, I; Thörn, SE; Wattwil, L; Wattwil, M, 2002)
"A decrease in the rate of gastric emptying can delay resumption of enteral feeding, alter bioavailability of orally administered drugs, and result in larger residual gastric volumes, increasing the risk of nausea and vomiting."	2.69	Delayed postoperative gastric emptying following intrathecal morphine and intrathecal bupivacaine. ( Cooke, T; Duggan, F; Lydon, AM; Shorten, GD, 1999)
"Acetaminophen does not inhibit this synthesis at the inflammatory site."	2.55	Pharmacology of Acetaminophen, Nonsteroidal Antiinflammatory Drugs, and Steroid Medications: Implications for Anesthesia or Unique Associated Risks. ( Candido, KD; Knezevic, NN; Perozo, OJ, 2017)
"Opioids are a key risk factor for postoperative nausea and vomiting (PONV)."	2.49	Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. ( Apfel, CC; Hornuss, C; Pergolizzi, J; Souza, K; Turan, A, 2013)
"Treatment of postoperative pain is imperative for inpatients, but is even more important for patients who are treated on an outpatient basis."	2.41	Treatment of postoperative pain after ophthalmic surgery. ( Coppens, M; Mortier, E; Versichelen, L, 2002)
" Dose-response relationships show that higher doses of ibuprofen may be particularly effective."	2.40	Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. ( McQuay, HJ; Moore, RA, 1998)
"Remifentanil is an ultrashort-acting opioid that provides quick and efficient analgesia but is associated with the induction of opioid-induced hyperalgesia."	1.56	Remifentanil for abdominal surgery is associated with unexpectedly unfavorable outcomes. ( Guenther, F; Heyn, J; Küchenhoff, H; Luchting, B; Niedermayer, S, 2020)
"Oral morphine was prescribed in 59/199 (30% [23; 37]) centres, for home treatment in 25/59 (42% [30; 56]) centres."	1.51	Perioperative pain and post-operative nausea and vomiting (PONV) management after day-case surgery: The SFAR-OPERA national study. ( Albaladejo, P; Aubrun, F; Benhamou, D; Bosson, JL; Diemunsch, P; Ecoffey, C; Jouffroy, L; Skaare, K, 2019)
"Postoperative pain was scored using the Oucher visual analog scale and nausea scored using a five point scale."	1.33	An evaluation of pain and postoperative nausea and vomiting following the introduction of guidelines for tonsillectomy. ( Nolan, JA; White, MC, 2005)

Research

Studies (93)

Authors

Clinical Trials (46)

Trial Overview

Trial Outcomes

Intensive Care Delirium Screening Checklist (ICDSC)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (7.53)	18.2507
2000's	33 (35.48)	29.6817
2010's	43 (46.24)	24.3611
2020's	10 (10.75)	2.80

Authors	Studies
Cao, Q	1
Fan, C	1
Yuan, R	1
Dong, H	1
Zhang, S	1
Meng, H	1
Bozorgmanesh, M	1
Valibeik, S	1
Shokrpour, M	1
Maktabi, M	1
Kamali, A	1
Myler, CS	1
Chapman, MR	1
Eden, BD	1
Lehman, EB	1
Karamchandani, K	1
Niedermayer, S	1
Heyn, J	1
Guenther, F	1
Küchenhoff, H	1
Luchting, B	1
Taniguchi, H	1
Nagahuchi, M	1
Kamada, T	1
Suga, K	1
Sato, T	1
Ueda, T	1
Yamamoto, T	1
Nguyen, BK	1
Stathakios, J	1
Quan, D	1
Pinto, J	1
Lin, H	1
Pashkova, AA	1
Svider, PF	1
Gan, TJ	1
Belani, KG	1
Bergese, S	1
Chung, F	1
Diemunsch, P	2
Habib, AS	1
Jin, Z	1
Kovac, AL	1
Meyer, TA	1
Urman, RD	1
Apfel, CC	3
Ayad, S	1
Beagley, L	1
Candiotti, K	1
Englesakis, M	1
Hedrick, TL	1
Kranke, P	1
Lee, S	1
Lipman, D	1
Minkowitz, HS	1
Morton, J	1
Philip, BK	1
Abdelaziz, DH	1
Boraii, S	1
Cheema, E	1
Elnaem, MH	1
Omar, T	1
Abdelraouf, A	1
Mansour, NO	1
Liu, J	1
Di, J	1
Zhang, Y	1
Xing, E	1
Pourfakhr, P	1
Aghabagheri, M	1
Zabihi Mahmoudabadi, H	1
Najjari, K	1
Talebpour, M	1
Khajavi, MR	1
Candido, KD	1
Perozo, OJ	1
Knezevic, NN	1
Koyuncu, O	1
Leung, S	1
You, J	1
Oksar, M	1
Turhanoglu, S	1
Akkurt, C	1
Dolapcioglu, K	1
Sahin, H	1
Sessler, DI	1
Turan, A	3
Aksoy, M	1
İnce, İ	1
Ahıskalıoğlu, A	1
Keleş, S	1
Doymuş, Ö	1
Hickman, SR	1
Mathieson, KM	1
Bradford, LM	1
Garman, CD	1
Gregg, RW	1
Lukens, DW	1
Chiu, C	1
Aleshi, P	1
Esserman, LJ	1
Inglis-Arkell, C	1
Yap, E	1
Whitlock, EL	1
Harbell, MW	1
Ducloyer, JB	1
Couret, C	1
Magne, C	1
Lejus-Bourdeau, C	1
Weber, M	2
Le Meur, G	1
Lebranchu, P	1
Aubrun, F	1
Ecoffey, C	1
Benhamou, D	1
Jouffroy, L	1
Skaare, K	1
Bosson, JL	1
Albaladejo, P	1
Castro Alves, LJ	1
Kendall, MC	1
Jotić, A	1
Savić Vujović, K	1
Milovanović, J	1
Vujović, A	1
Radin, Z	1
Milić, N	1
Vučković, S	1
Medić, B	1
Prostran, M	1
Souza, K	1
Pergolizzi, J	1
Hornuss, C	1
Mathiesen, O	4
Dahl, B	1
Thomsen, BA	2
Kitter, B	2
Sonne, N	1
Dahl, JB	5
Kehlet, H	4
McNicol, E	1
Schumann, R	1
Subramanyam, R	1
Varughese, A	1
Kurth, CD	1
Eckman, MH	1
Ramirez, L	1
Cros, J	1
Marin, B	1
Boulogne, P	1
Bergeron, A	1
de Lafont, GE	1
Renon-Carron, F	1
de Vinzelles, MA	1
Guigonis, V	1
Nathan, N	1
Beaulieu, P	1
El Batawi, HY	1
Mohamed, SJ	1
Kristensen, BB	1
Lindgaard, L	1
Bisgaard, T	1
Fearon, JA	1
Dimas, V	1
Ditthakasem, K	1
Herbert, MA	1
Kim, EJ	1
Shim, JK	1
Soh, S	1
Song, JW	1
Lee, SR	1
Kwak, YL	1
Morgan, B	1
Stanik-Hutt, J	1
Ohkura, Y	1
Haruta, S	1
Shindoh, J	1
Tanaka, T	1
Ueno, M	1
Udagawa, H	1
Naja, Z	1
Kanawati, S	1
Al Khatib, R	1
Ziade, F	1
Naja, ZZ	1
Naja, AS	1
Rajab, M	1
Ng, TT	1
Diamantaras, D	1
Priestley, J	1
Redman, J	1
De Silva, N	1
Mahanta, V	1
Gärtner, R	2
Callesen, T	2
Kroman, N	2
Rasmussen, ML	1
Dierking, G	1
Lech, K	1
Hilsted, KL	1
Fomsgaard, JS	2
Lose, G	1
Ali, M	1
Khan, FA	1
Ohnesorge, H	1
Bein, B	1
Hanss, R	1
Francksen, H	1
Mayer, L	1
Scholz, J	1
Tonner, PH	1
Mattila, K	1
Kontinen, VK	1
Kalso, E	2
Hynynen, MJ	1
Utvoll, J	1
Beausang-Linder, M	1
Mesic, H	1
Raeder, J	1
Kanazi, GE	1
Aouad, MT	1
Abdallah, FW	1
Khatib, MI	1
Adham, AM	1
Harfoush, DW	1
Siddik-Sayyid, SM	1
Sandhu, T	1
Paiboonworachat, S	1
Ko-iam, W	1
Gurnaney, H	1
Ganesh, A	1
Yagoubian, B	1
Akkara, J	1
Afzali, P	1
Alfi, DM	1
Olson, L	1
Conell-Price, J	1
Yeh, J	1
Eisig, SB	1
Flood, P	1
Maund, E	1
McDaid, C	1
Rice, S	1
Wright, K	1
Jenkins, B	1
Woolacott, N	1
Uysal, HY	1
Takmaz, SA	1
Yaman, F	1
Baltaci, B	1
Başar, H	1
Iodice, FG	1
Thomas, M	1
Walker, I	1
Garside, V	1
Elliott, MJ	1
Moon, YE	1
Lee, YK	1
Lee, J	1
Moon, DE	1
Platzer, M	1
Likar, R	1
Stettner, H	1
Jost, R	1
Wutti, C	1
Leipold, H	1
Breschan, C	1
Richebé, P	1
Pouquet, O	1
Jelacic, S	1
Mehta, S	1
Calderon, J	1
Picard, W	1
Rivat, C	1
Cahana, A	1
Janvier, G	1
Rawlinson, E	1
Walker, A	1
Skone, R	1
Thillaivasan, A	1
Bagshaw, O	1
Cok, OY	1
Eker, HE	1
Pelit, A	1
Canturk, S	1
Akin, S	1
Aribogan, A	1
Arslan, G	1
Rawlinson, A	1
Kitchingham, N	1
Hart, C	1
McMahon, G	1
Ong, SL	1
Khanna, A	1
Jaeger, P	1
Grevstad, U	1
Henningsen, MH	1
Gottschau, B	1
Wenk, M	1
Pöpping, DM	1
Chapman, G	1
Grenda, H	1
Ledowski, T	1
Tunali, Y	1
Akçil, EF	1
Dilmen, OK	1
Tutuncu, AC	1
Koksal, GM	1
Akbas, S	1
Vehid, H	1
Yentur, E	1
Wattwil, M	1
Thörn, SE	1
Lövqvist, A	1
Wattwil, L	1
Klockhoff, H	1
Larsson, LG	1
Näslund, I	1
Issioui, T	2
Klein, KW	2
White, PF	3
Watcha, MF	2
Skrivanek, GD	1
Jones, SB	1
Hu, J	1
Marple, BF	1
Ing, C	1
Abdulatif, M	1
El-Sanabary, M	1
Coppens, M	1
Versichelen, L	1
Mortier, E	1
Madadaki, C	1
Laffon, M	1
Lesage, V	1
Blond, MH	1
Lescanne, E	1
Mercier, C	1
O'Flaherty, JE	1
Lin, CX	1
Batra, YK	1
Arya, VK	1
Mahajan, R	1
Chari, P	1
Wagner, D	1
Pandit, U	1
Voepel-Lewis, T	2
Karamanlioglu, B	1
Memis, D	1
Süt, N	1
Farmery, AD	1
Shlugman, D	1
Rahman, R	1
Rosen, P	1
White, MC	1
Nolan, JA	1
Marcus, RL	1
Wong, CA	1
Lehor, A	1
McCarthy, RJ	1
Yaghmour, E	1
Yilmaz, M	1
Pettersson, PH	1
Jakobsson, J	1
Owall, A	1
Legeby, M	1
Sandelin, K	1
Wickman, M	1
Olofsson, C	1
Recart, A	1
Duchene, D	1
Thomas, T	1
Johnson, DB	1
Cadeddu, JA	1
Lin, HM	1
Chelly, JE	1
Puura, A	1
Puolakka, P	1
Rorarius, M	1
Salmelin, R	1
Lindgren, L	1
Kemppainen, T	1
Kokki, H	1
Tuomilehto, H	1
Seppä, J	1
Nuutinen, J	1
Cattabriga, I	1
Pacini, D	1
Lamazza, G	1
Talarico, F	1
Di Bartolomeo, R	1
Grillone, G	1
Bacchi-Reggiani, L	1
Kavanagh, T	1
Hu, P	1
Minogue, S	1
Tiippana, E	1
Bachmann, M	1
Pere, P	1
Munro, HM	1
D'Errico, CC	1
Lauder, GR	1
Wagner, DS	1
Tait, AR	1
McQuay, HJ	1
Moore, RA	1
Barst, SM	1
Leiderman, JU	1
Markowitz, A	1
Rosen, AM	1
Abramson, AL	1
Bienkowski, RS	1
Walker, R	1
Dearlove, OR	1
Aguilera, I	1
Lydon, AM	1
Cooke, T	1
Duggan, F	1
Shorten, GD	1
Van Lancker, P	1
Vandekerckhove, B	1
Cooman, F	1
Pluim, MA	1
Wegener, JT	1
Rupreht, J	1
Vulto, AG	1
Nolan, J	1
Prosser, DP	1
Ho, D	1
Keneally, JP	1
Bremerich, DH	1
Neidhart, G	1
Heimann, K	1
Kessler, P	1
Behne, M	1
Silvasti, M	1
Pitkänen, M	1
Dejonckheere, M	1
Desjeux, L	1
Deneu, S	1
Ewalenko, P	1
Enever, GR	1
Nunn, JH	1
Sheehan, JK	1
Jørgensen, H	1
Dirks, J	1
Wetterslev, J	1
Andreasson, B	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
The Effect of Cold Application on Nausea and Vomiting After Laparoscopic Cholecystectomy[NCT06008262]		54 participants (Anticipated)	Interventional	2023-07-03	Enrolling by invitation
Evaluation of the Effect of APFEL Risk Score and Fasting Periods on Postoperative Nausea and/or Vomiting[NCT06022705]		250 participants (Anticipated)	Observational [Patient Registry]	2023-08-28	Recruiting
A Comparison Between Palonosetron And Ondansetron As Prophylaxis Against Postoperative Nausea and Vomiting In Idiopathic Scoliosis Surgery: A Randomised Trial[NCT05956899]	Phase 4	74 participants (Anticipated)	Interventional	2023-06-01	Recruiting
The Effect of Cold Vapor on Nausea and Vomiting in the Early Postoperative Period After Laparoscopic Cholecystectomy[NCT05302128]		84 participants (Anticipated)	Interventional	2022-04-11	Not yet recruiting
Triple Combination of Fosaprepitant, Dexamethasone and Palonosetron Versus Combination of Dexamethasone and Palonosetron for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gastrointestinal Surgery[NCT04853147]	Phase 3	1,154 participants (Actual)	Interventional	2021-04-27	Completed
The Effects of Intravenous Fosaprepitant and Ondansetron for the Prevention of Postoperative Nausea and Vomiting in Thoracicsurgery Patients: A Single-center, Randomized, Double-Blinded Clinical Study[NCT05881486]		234 participants (Anticipated)	Interventional	2023-06-30	Not yet recruiting
Preoperative Pregabalin to Prevent Postoperative Nausea & Vomiting in Laparoscopic Surgery.[NCT05529004]	Phase 2	100 participants (Anticipated)	Interventional	2022-09-30	Not yet recruiting
Effect of Remimazolam on Incidence of Postoperative Nausea and Vomiting Following General Anesthesia in High-risk Patients: a Multicenter, Double-blinded, Placebo-controlled Randomized Trial[NCT04861337]	Phase 4	552 participants (Actual)	Interventional	2021-05-19	Completed
The Comparison of P6+ST36 Combination Acupuncture Therapy With P6 Alone Acupuncture and Standard Treatment in Postoperative Nausea and Vomiting[NCT04866121]		105 participants (Anticipated)	Interventional	2021-05-01	Recruiting
Organisation PERiopératoire de l'anesthésie et de la Chirurgie Ambulatoire[NCT02380430]		2,174 participants (Actual)	Observational	2014-04-30	Completed
Role of Scheduled Intravenous Acetaminophen for Postoperative Pain Management in an Enhanced Recovery After Surgery (ERAS) Population: A Prospective, Randomized, Double-Blind and Placebo-Controlled Clinical Trial[NCT03198871]	Phase 4	180 participants (Actual)	Interventional	2018-05-24	Completed
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty[NCT03498261]	Phase 1	50 participants (Actual)	Interventional	2018-01-30	Active, not recruiting
Erector Spinae Plane Block in Lumbar Spinal Fusion : Double-blind, Randomized Controlled Trial.[NCT04904575]		130 participants (Anticipated)	Interventional	2022-01-03	Recruiting
Erector Spinae Plane Block in Lumbar Release Surgery : Double-blind, Randomized Controlled Trial[NCT04925882]		100 participants (Actual)	Interventional	2022-01-03	Completed
Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543]		90 participants (Actual)	Interventional	2014-06-30	Completed
Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion[NCT03035656]	Phase 4	228 participants (Anticipated)	Interventional	2019-03-01	Not yet recruiting
Evaluation of Post-operative Pain in Bascom Cleft Lift Operation Receiving Multimodal Analgesia and Spinal Saddle Block in Day Case Surgery Setting.[NCT02196727]		32 participants (Actual)	Observational [Patient Registry]	2013-05-31	Completed
The Effect of Dexamethasone Versus Local Infiltration Technique on Postoperative Nausea and Vomiting After Tonsillectomy in Children: A Randomized Double-blind Clinical Trial[NCT02355678]		129 participants (Actual)	Interventional	2015-01-31	Completed
The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy: A Prospective, Double Blinded, Placebo Controlled Study[NCT01106547]	Phase 4	55 participants (Anticipated)	Interventional	2009-08-31	Completed
Preoperative Use of Pregabalin and Analgesia Levels After Laparoscopic Cholecystectomy[NCT01321801]		50 participants (Actual)	Interventional	2009-11-30	Completed
Comparison of Tramadol vs. Tramadol With Paracetamol for Efficacy of Postoperative Pain Management in Lumbar Discectomy: A Randomised Controlled Trial[NCT03482492]		60 participants (Actual)	Interventional	2014-03-20	Completed
Effectiveness of Transversus Abdominis Plane Block Versus Quadratus Lumborum Technique in Patients After Cesarean Section[NCT02804126]	Phase 4	232 participants (Actual)	Interventional	2017-06-01	Completed
Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial[NCT01904266]		60 participants (Actual)	Interventional	2013-05-31	Completed
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study[NCT04875559]		236 participants (Actual)	Observational [Patient Registry]	2021-04-19	Completed
The Effect of Paracetamol on Postoperative Nausea and Vomiting Following Maxillofacial Surgery: a Prospective, Randomised, Double-blind Study[NCT03588338]	Phase 4	90 participants (Actual)	Interventional	2018-07-20	Completed
Anaesthesiological Involvement in Postoperative Pain Treatment - A Questionnaire Survey at Danish Hospitals[NCT03496194]		42 participants (Actual)	Observational	2018-04-13	Completed
Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty[NCT03915522]		140 participants (Anticipated)	Interventional	2018-05-14	Recruiting
Prospective, Randomized, Double-Blinded, Allocation Concealed Study Comparing the Efficacy of Liposomal Bupivacaine Over Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Primary Total Knee Arthro[NCT02624856]	Phase 4	0 participants (Actual)	Interventional	2015-11-30	Withdrawn (stopped due to Lack of funding)
Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty[NCT01759277]	Phase 4	80 participants (Actual)	Interventional	2012-12-31	Completed
Prospective, Double-blind, Randomized Study to Evaluate a Single Shot Adductor Canal Nerve Block Versus Femoral Nerve Block Combined With LIA (Local Infiltration Analgesia): Early Postoperative Period Functional Outcomes After Total Knee Replacement[NCT02218814]		106 participants (Actual)	Interventional	2014-08-31	Completed
Adductor Canal Mid-thigh and Adductor Canal Distal Thigh: Is Cutaneous Sensory Blockade Similar Among Block Techniques?[NCT02788019]	Phase 4	52 participants (Actual)	Interventional	2016-05-26	Terminated (stopped due to Unable to complete the sample size needed for 80% power due to changes in surgical approach to adductor block usage.)
The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty[NCT01261897]	Phase 4	40 participants (Anticipated)	Interventional	2011-01-31	Completed
Optimal Volume of Bupivacaine in Adductor Canal Nerve Block in Patients Undergoing Unilateral Cruciate Ligament Reconstruction Surgery[NCT02557386]	Phase 4	60 participants (Anticipated)	Interventional	2016-01-31	Recruiting
Ultrasound Guided Single Shot Adductor Canal Block (ACB) Versus Single Shot Femoral Nerve Block (FNB) for Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament (ACL) Reconstruction in Pediatrics[NCT03053401]		52 participants (Actual)	Interventional	2017-02-09	Completed
Continuous Adductor Canal Block With Epidural Analgesia for Total Knee Arthroplasty: A Prospective, Randomized, Double-blinded, Placebo-Controlled Trial[NCT02121392]		165 participants (Actual)	Interventional	2014-10-31	Completed
Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder Surgery: Prospective, Randomized, Double-Blind Clinical Trial[NCT05401916]		2 participants (Actual)	Interventional	2022-06-10	Completed
Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial[NCT04691856]		66 participants (Actual)	Interventional	2020-12-24	Completed
Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial[NCT03437707]		3 participants (Actual)	Interventional	2018-02-13	Completed
A Phase 3, Multicenter, Randomized, Double-Masked Clinical Trial to Assess the Efficacy and Safety of Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% Compared to Placebo in the Treatment of Inflammation and Pain Associated With Cataract Surgery[NCT04249076]	Phase 3	215 participants (Actual)	Interventional	2020-06-04	Completed
A Phase 3, Multicenter, Randomized, Double-Masked Clinical Trial to Assess the Efficacy and Safety of Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% Compared to Placebo in the Treatment of Inflammation and Pain Associated With Cataract Surgery[NCT04246801]	Phase 3	250 participants (Actual)	Interventional	2020-06-10	Completed
The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Cesarean Delivery[NCT02257346]		0 participants (Actual)	Interventional	2014-11-01	Withdrawn (stopped due to PI terminated study with no subjects enrolled.)
The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Outpatient Gynecologic Laparoscopy[NCT01250002]		70 participants (Actual)	Interventional	2010-11-30	Completed
Erector Spinae Plane Block (ESPB): A New Technique for Perioperative Pain Control in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.[NCT03691935]	Phase 4	40 participants (Anticipated)	Interventional	2018-09-28	Enrolling by invitation
Intravenous Acetaminophen as Adjuvant Therapy for Pain Control in Geriatric Hip Fracture Patients[NCT01520298]	Phase 3	0 participants (Actual)	Interventional	2011-12-31	Withdrawn (stopped due to Difficulty in recruiting subjects for the trial.)
Ambulant Laparoscopic Nephrectomy[NCT01600157]		62 participants (Actual)	Interventional	2013-04-30	Completed
An Open-label Non-randomized Phase IV Trial of the Clinical Efficacy of Intravenously Administered 1000mg Paracetamol as Antipyretic and Analgesic Medication[NCT01070732]	Phase 4	100 participants (Actual)	Interventional	2010-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Number of patients who score greater than a 4 on the 0-8 point ICDSC scale to assess delirium scores. 8 separate levels of signs for delirium assessed (1. altered level of consciousness, 2. inattention, 3. disorientation, 4. hallucination, delusion, or psychosis, 5. psychomotor agitation or retardation, 6. inappropriate speech or mood, 7. sleep-wake cycle disturbance, 8. symptom fluctuation), with 0 points awarded when patient does not exhibit above signs of delirium and 1 point awarded per confirmed sign of delirium. Score then totaled, 0 = normal, 1-3 = subsyndromal delirium, 4-8 = delirium. (NCT03198871)
Timeframe: The delirium scores will first be measured every 12 hours for 72 hours after surgery.

Number of Participants With Readmission to the Hospital

Intervention	Participants (Count of Participants)
Acetaminophen Injectable Product	0
Sodium Chloride 0.9%, Intravenous	0

If the patient is readmitted to the hospital after being fully discharged, the event will be recorded. (NCT03198871)
Timeframe: From the time of consent until 30 days post-operatively

Postoperative Pain Intensity

Intervention	Participants (Count of Participants)
Acetaminophen Injectable Product	9
Sodium Chloride 0.9%, Intravenous	10

Number of patients with unsatisfactory pain relief defined as average numeric rating scale (NRS) more than 5 will be compared between the two groups. This may include patients using IVPCA for pain relief during the first 48 hours postoperative. (NCT03198871)
Timeframe: PACU admission every thirty minutes until discharge to the floor and thereafter every four hours for first 24-hour, then every six hours until 48 hours and then every twelve hours until 72 hours postoperatively.

Time to Ambulation

Intervention	Participants (Count of Participants)
Acetaminophen Injectable Product	33
Sodium Chloride 0.9%, Intravenous	42

The time it takes for the patient to successfully ambulate post-surgery will be measured. (NCT03198871)
Timeframe: From date of PACU admission until the date of first documented ambulation, assessed up to 72 hours postoperatively

Time to Bowel Movement

Intervention	hours (Median)
Acetaminophen Injectable Product	18.82
Sodium Chloride 0.9%, Intravenous	17.38

The time it takes for the first bowel movement postoperatively will be measured. (NCT03198871)
Timeframe: From time patient left operating room until the time of first documented bowel movement, assessed up to hospital discharge

Time to Hospital Discharge

Intervention	hours (Median)
Acetaminophen Injectable Product	46.30
Sodium Chloride 0.9%, Intravenous	64.66

The time it takes for the patient to be fully discharged from the hospital post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of hospital discharge or 30 days postoperatively, whichever comes first

Time to Oral Intake

Intervention	days (Median)
Acetaminophen Injectable Product	4.08
Sodium Chloride 0.9%, Intravenous	4.94

The time it takes for the patient to ingest orally post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of first documented oral intake, assessed up to 72 hours postoperatively

Time to Readiness for Discharge From Post Anesthesia Care Unit (PACU)

Intervention	hours (Median)
Acetaminophen Injectable Product	12.15
Sodium Chloride 0.9%, Intravenous	9.40

The time from PACU admission to PACU discharge to the floor will be measured. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge, assessed up to 24 hours postoperatively

Patient Satisfaction

Intervention	minutes (Median)
Acetaminophen Injectable Product	129.00
Sodium Chloride 0.9%, Intravenous	152.50

Overall patient satisfaction as well as satisfaction relating to pain management and cost analyses will be measured. These will be measured with a numerical rating scale (NRS) with 0- being worst satisfaction and 10 - best satisfaction. (NCT03198871)
Timeframe: These measurements will be taken at time of discharge up to 30 days, whichever comes first

Post-operative Emesis

Intervention	score on a scale (Median)
	Patient satisfaction score, overall	Patient Satisfaction score, pain management
Acetaminophen Injectable Product	10	10
Sodium Chloride 0.9%, Intravenous	10	10

Frequency of emesis and rescue antiemetic requirement will be documented (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.

Post-operative Nausea

Intervention	Participants (Count of Participants)
	Emesis incidence 0-72 hours	Antiemetic use
Acetaminophen Injectable Product	12	31
Sodium Chloride 0.9%, Intravenous	14	45

Nausea will be evaluated by nausea score from 0 to 10, with 0 equaling no nausea and 10 equaling the worst nausea imaginable. (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.

SF-12 Health Survey

Intervention	score on a scale (Mean)
	Nausea score POD 1 (am visit)	Nausea score POD 1 (pm visit)	Nausea score POD 2 (am visit)	Nausea score POD 2 (pm visit)	Nausea score POD 3 (am visit)	Nausea score POD 3 (pm visit)
Acetaminophen Injectable Product	1.13	0.49	0.71	0.55	0.32	0.56
Sodium Chloride 0.9%, Intravenous	0.60	0.92	0.75	0.69	0.66	0.78

Survey to assess patient's overall health (via a combination of mental and physical health assessment) at 30 days post-discharge. Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12). The scores may be reported as Z-scores (difference compared to the population average, measured in standard deviations). The United States population average PCS-12 and MCS-12 are both 50 points. The United States population standard deviation is 10 points. So each 10 increment of 10 points above or below 50, corresponds to one standard deviation away from the average (NCT03198871)
Timeframe: These measurements will take place at 30-days post hospital discharge

Total Post-operative Narcotic Consumption

Intervention	Z-scores (difference compared to the pop (Median)
	SF 12 Physical score	SF 12 Mental score
Acetaminophen Injectable Product	38.72	54.02
Sodium Chloride 0.9%, Intravenous	38.07	52.08

Rescue analgesia will be given according to institutional pain management protocol. Unit of Measure recorded as OME (Oral Morphine Equivalent) consumption in mg. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge and 72-hours postoperatively, whichever comes first

Hours Until Discharge Readiness

Intervention	mg (Median)
	0-24 hours	24-48 hours	48-72 hours	0-48 hours	0-72 hours
Acetaminophen Injectable Product	27.4	31.3	30	74	105.00
Sodium Chloride 0.9%, Intravenous	36	45	37.5	88.8	127.1

Discharge readiness is the number of hours until meeting the following 4 criteria: (1) adequate analgesia (defined as pain less than 4 on a NRS of 0-10); (2) independence from intravenous analgesics; (3) ability to ambulate 30 m and (4) ability to stand, walk 3 m, and return to a sitting position without another's assistance. (NCT01759277)
Timeframe: 7 postoperative days

Time to Adequate Analgesia

Intervention	hours (Median)
Control	61
Experimental	55

The time in hours until adequate analgesia is defined as pain less than 4 on a Numeric Rating Scale of 0-10, with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: First 7 postoperative days

Time Until Ambulation at Least 30 Meters

Intervention	Hours (Mean)
Control	61.6
Experimental	61.0

The time in hours until a patient could ambulate at least 30 meters independently (regardless of time to achieve the 30 meters) (NCT01759277)
Timeframe: 7 postoperative days

Time Until Independence From Intravenous Analgesics of at Least 12 Hours

Intervention	Hours (Mean)
Control	40.9
Experimental	56.6

The time in hours until no intravenous analgesics were required for at least 12 hours (without future intravenous use during admission) (NCT01759277)
Timeframe: First 7 postoperative days

Time Until Timed Up and Go Test Achieved

Intervention	Hours (Mean)
Control	46.1
Experimental	47.5

The timed-up-and-go (TUG) test measures the ability and speed of standing from a sitting position, walking 3 meters and returning to the original seated position independent from the assistance of healthcare personnel. This variable measured the time in hours until the patient could successfully achieve this test independently, regardless of the amount of time required. (NCT01759277)
Timeframe: Hours

Opioid Consumption

Intervention	Hours (Mean)
Control	33.4
Experimental	46.8

Amount of opioid consumed as measured with intravenous morphine equivalents in milligrams (NCT01759277)
Timeframe: Postoperative Days 0-3

Pain Level

Intervention	milligrams (Mean)
	Recovery Room	Postoperative Day 0 (day)	Postoperative Day 0 (evening)	Postoperative Day 1 (night)	Postoperative Day 1 (Day)	Postoperative Day 1 (evening)	Postoperative Day 2 (night)	Postoperative Day 2 (day)	Postoperative Day 2 (evening)	Postoperative Day 3 (night
Control	8.6	0.9	7.2	5.1	11.0	8.6	4.1	9.6	6.5	4.9
Experimental	8.0	1.5	8.5	5.6	12.6	10.9	5.6	10.2	7.2	5.1

The amount of pain evaluated using the 0-10 Numeric Rating Scale with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: Postoperative Days 1-3

Number of Grid Points With Change of Sensation to Pinprick After Blockade

Intervention	score on a scale (Mean)
	Postoperative Day 1 (08:00-16:00)	Postoperative Day 2 (08:00-16:00)	Postoperative Day 3 (00:00-8:00)
Control	4.4	3.7	2.5
Experimental	3.7	3.4	2.8

The distribution of cutaneous sensation affected by the different techniques of adductor canal blockade is assessed using a monofilament Neuropen to prick points on a 20 point grid applied to the skin in a standard fashion according to this method: A grid will be marked starting with anatomical landmarks at the knee joint: the medial inter-knee-joint point where the tibia meets the femur, the mid medial patella, the mid lateral patella, and along the same line at the semitendinosus tendon and 5cm posterior from that point. Then 5cm intervals will be plotted progressing cephalad to a total of 15 centimeters. This will yield 20 grid points (5x4 points). Once the grid is made, testing proceeds with a Neuropen on a scale of 0-1, with 1 = normal sharp sensation, 0 = change of sensation. The Neuropen is used for the standardization of force. (NCT02788019)
Timeframe: 20 minutes

Quadriceps Muscle Strength in Kilogram-force (Kgf)

Intervention	points of cutaneous sensation (Mean)
Mid-Thigh Adductor Block	19.81
Distal-Thigh Adductor Block	20

Measuring the quadriceps muscle strength (surgical side) using a dynamometer.Patients were placed supine with a cushion underneath their knee, resulting in a 45-degree angle at the knee. A dynamometer was placed on the anterior of the ankle, between the malleoli. Patients were instructed to extend their legs three times each, with a 30-s pause between each attempt (Lafayette Manual Muscle Test System; Lafayette Instrument Company, Lafayette, IN; and all three dynamometer readings in Kgf unit for each leg were recorded.Kgf is a gravitational metric unit force ,it is equal to the magnitude of the force exerted on one kilogram of mass under standard gravity. (NCT03053401)
Timeframe: 4 hours following peripheral nerve block performance

Total Opioid Consumption at 24 Hours Post-block

Intervention	Kilogram-force (Kgf) (Median)
Adductor Canal Block	1.1
Femoral Nerve Block	0.0

Total intravenous morphine/morphine equivalent consumption in milligrams (mg) at 24 hours post-block (NCT03053401)
Timeframe: 24 hours following peripheral nerve block performance.

Post-operative Pain Scores Using the Numeric Pain Scoring System (NS)

Intervention	milligrams (Mean)
Adductor Canal Block	28.9
Femoral Nerve Block	26.9

Assessed by Numeric Scale (NS) pain scoring system. Minimum 0 and maximum 10 . Higher scores means worse outcome (pain) (NCT03053401)
Timeframe: 4 hours and 24 hours

Number of Hospital Days Until Discharge Criteria Are Met

Intervention	score on a scale (Median)
	4 hours post block	24 hours post block
Adductor Canal Block	4.5	5.0
Femoral Nerve Block	4.5	6.0

(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery

Number of Participants With Adverse Events Related to Adductor Canal Nerve Block Catheter

Intervention	Days (Mean)
Epidural Catheter Without Adductor Canal Nerve Block Catheter	2.42
Epidural Catheter With Adductor Canal Nerve Block Catheter	2.67

(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery

Number of Participants With Bleeding Complications at Adductor Canal Nerve Block Catheter Site

Intervention	Participants (Count of Participants)
Epidural Catheter Without Adductor Canal Nerve Block Catheter	0
Epidural Catheter With Adductor Canal Nerve Block Catheter	0

(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery

Morphine Equivalents

Intervention	Participants (Count of Participants)
Epidural Catheter Without Adductor Canal Nerve Block Catheter	0
Epidural Catheter With Adductor Canal Nerve Block Catheter	0

(NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter

Physical Therapy Ambulation Distance

Range of Motion

Intervention	milligrams of morphine (Mean)
	12 hours postoperatively	20 hours after placement of catheter
Epidural Catheter With Adductor Canal Nerve Block Catheter	12.5	73.9
Epidural Catheter Without Adductor Canal Nerve Block Catheter	11.9	96.5

Intervention	meters (Mean)
	Postoperative Day 1	Postoperative Day 2
Epidural Catheter With Adductor Canal Nerve Block Catheter	17.6	39.4
Epidural Catheter Without Adductor Canal Nerve Block Catheter	13.8	32.5

Knee range of motion (ROM) was measured (in degrees) during physical therapy. (NCT02121392)
Timeframe: postoperative day 1 and 2

Range of Motion at 3 and 6 Week Follow up

Visual Analog Score for Pain

Intervention	degrees (Mean)
	Postoperative Day 1	Postoperative Day 2
Epidural Catheter With Adductor Canal Nerve Block Catheter	40.6	62.5
Epidural Catheter Without Adductor Canal Nerve Block Catheter	51.4	71.3

Intervention	degrees (Mean)
	3 weeks	6 weeks
Epidural Catheter With Adductor Canal Nerve Block Catheter	94.3	105
Epidural Catheter Without Adductor Canal Nerve Block Catheter	98.2	109

"The visual analog scale (VAS) is a pain rating scale. Scores are based on self-reported measures of symptoms that are recorded with a single mark placed at one point along the length of a line that represents a continuum between the two ends of the scale-no pain on the left end of the scale (equal to a score of 0) and the worst pain on the right end of the scale (equal to a score of 100)." (NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

Intervention	mm (Mean)
	12 hours postoperatively	20 hours after placement of catheter
Epidural Catheter With Adductor Canal Nerve Block Catheter	26.9	28.6
Epidural Catheter Without Adductor Canal Nerve Block Catheter	27.9	36.4

The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation of Hip and Knee Osteoarthritis. It is a self administered questionnaire consisting of 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). The subscale scores can vary, with pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations. A sum of the scores for all three subscales yields a total WOMAC score. (NCT02121392)
Timeframe: 3 and 6 weeks

Anterior Chamber Cell Grade

Intervention	score on a scale (Mean)
	3 weeks	6 weeks
Epidural Catheter With Adductor Canal Nerve Block Catheter	29.1	27.9
Epidural Catheter Without Adductor Canal Nerve Block Catheter	37.8	32.9

"Percentage of participants with anterior chamber cell grade of 0 (absence of cells)" (NCT04249076)
Timeframe: Day 8

Pain Visual Analogue Scale (VAS) Score

Intervention	Participants (Count of Participants)
Clobetasol Propionate	38
Placebo	7

"Percentage of participants with VAS pain score of 0 (no eye pain)" (NCT04249076)
Timeframe: Day 8

Anterior Chamber Cell Grade

Intervention	Participants (Count of Participants)
Clobetasol Propionate	68
Placebo	31

"Percentage of participants with anterior chamber cell grade of 0 (absence of cells)" (NCT04246801)
Timeframe: Day 8

Pain Visual Analogue Scale (VAS) Score

Intervention	Participants (Count of Participants)
Clobetasol Propionate	67
Placebo	18

"Percentage of participants with VAS pain score of 0 (no eye pain). Pain was scored by ticking on a continuous scale comprised of a 10 cm horizontal line anchored by two verbal descriptions: no eye pain (score of 0) and worst imaginable eye pain (score of 10)." (NCT04246801)
Timeframe: Day 8

Opioid Consumption (Morphine Equivalents)

Intervention	Participants (Count of Participants)
Clobetasol Propionate	83
Placebo	19

opioid consumption (morphine equivalents)post operatively (NCT01250002)
Timeframe: 24 hours

Quality of Recovery 40 Score

Intervention	mg (Median)
Group A (Study Group) Lidocaine	20
Placebo	30

Quality of recovery 40 score on the day after surgery. Scale ranges from a low of 40 (poor recovery) to a high of 200 (good recovery). (NCT01250002)
Timeframe: 24 hours post surgery

Article	Year
Comparison of intravenous and oral administration of acetaminophen in adults undergoing general anesthesia. Pain practice : the official journal of World Institute of Pain, 2022, Volume: 22, Issue:3 Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesics, Opioid; Anesthe	2022
Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review. The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:10 Topics: Acetaminophen; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Bas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. Anesthesia and analgesia, 2020, Volume: 131, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Antiemetics; Consensus; Diseas	2020
Pharmacology of Acetaminophen, Nonsteroidal Antiinflammatory Drugs, and Steroid Medications: Implications for Anesthesia or Unique Associated Risks. Anesthesiology clinics, 2017, Volume: 35, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Anti-Inflammatory Agents, N	2017
Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. Pain, 2013, Volume: 154, Issue:5 Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, General; Female; Humans; Injection	2013
Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery: a systematic review. British journal of anaesthesia, 2011, Volume: 106, Issue:3 Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Sche	2011
Mechanisms of reducing postoperative pain, nausea and vomiting: a systematic review of current techniques. Evidence-based medicine, 2012, Volume: 17, Issue:3 Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory	2012
Treatment of postoperative pain after ophthalmic surgery. Bulletin de la Societe belge d'ophtalmologie, 2002, Issue:285 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex	2002
Treatment of postoperative pain after ophthalmic surgery. Bulletin de la Societe belge d'ophtalmologie, 2002, Issue:285 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex	2002
Treatment of postoperative pain after ophthalmic surgery. Bulletin de la Societe belge d'ophtalmologie, 2002, Issue:285 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex	2002
Treatment of postoperative pain after ophthalmic surgery. Bulletin de la Societe belge d'ophtalmologie, 2002, Issue:285 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex	2002
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. Health technology assessment (Winchester, England), 1998, Volume: 2, Issue:12 Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio	1998

Article	Year
Effect of combined paracetamol and dexamethasone vs. paracetamol on postoperative nausea vomiting after cesarean section. Journal of perinatal medicine, 2022, Oct-26, Volume: 50, Issue:8 Topics: Acetaminophen; Antiemetics; Cesarean Section; Dexamethasone; Double-Blind Method; Female; Humans; Pa	2022
The intraperitoneal ondansetron for postoperative pain management following laparoscopic cholecystectomy: A proof-of-concept, double-blind, placebo-controlled trial. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 140 Topics: Acetaminophen; Adjuvants, Pharmaceutic; Adult; Analgesics; Antiemetics; Cholecystectomy, Laparoscopi	2021
Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. Inflammopharmacology, 2021, Volume: 29, Issue:4 Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Ag	2021
Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. Obesity surgery, 2021, Volume: 31, Issue:10 Topics: Acetaminophen; Antiemetics; Diphenhydramine; Double-Blind Method; Gastrectomy; Humans; Laparoscopy;	2021
The effect of ondansetron on analgesic efficacy of acetaminophen after hysterectomy: A randomized double blinded placebo controlled trial. Journal of clinical anesthesia, 2017, Volume: 40 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Double-Blind Method	2017
Effect of intravenous preoperative versus postoperative paracetamol on postoperative nausea and vomiting in patients undergoing strabismus surgery: A prospective randomized study. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2018, Volume: 30, Issue:1 Topics: Acetaminophen; Administration, Intravenous; Adolescent; Child; Child, Preschool; Drug Administration	2018
Randomized trial of oral versus intravenous acetaminophen for postoperative pain control. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2018, Mar-15, Volume: 75, Issue:6 Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Aged; Analgesics, Non-Narcotic; An	2018
Pain Management After Surgical Tonsillectomy: Is There a Favorable Analgesic? Ear, nose, & throat journal, 2019, Volume: 98, Issue:6 Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child; Female; Humans; I	2019
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013, Volume: 22, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges	2013
Analgesic interaction between ondansetron and acetaminophen after tonsillectomy in children: the Paratron randomized, controlled trial. European journal of pain (London, England), 2015, Volume: 19, Issue:5 Topics: Acetaminophen; Adenoidectomy; Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Analgesics, Opioid; A	2015
Effect of intraoperative analgesia on children's pain perception during recovery after painful dental procedures performed under general anaesthesia. European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2015, Volume: 16, Issue:1 Topics: Acetaminophen; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anti-Inflammator	2015
Acceptable effect of multimodal analgesic treatment after a Bascom cleft lift operation. Danish medical journal, 2015, Volume: 62, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Cyclohexaneca	2015
A Randomized Controlled Trial of Oral Versus Intravenous Administration of a Nonnarcotic Analgesia Protocol Following Pediatric Craniosynostosis Corrections on Nausea and Vomiting Rates. The Journal of craniofacial surgery, 2015, Volume: 26, Issue:6 Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anesthesia Recovery Perio	2015
Patient-controlled Analgesia With Propacetamol-Fentanyl Mixture for Prevention of Postoperative Nausea and Vomiting in High-risk Patients Undergoing Spine Surgery: A Randomized Controlled Trial. Journal of neurosurgical anesthesiology, 2016, Volume: 28, Issue:4 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Drug Ther	2016
The effect of IV dexamethasone versus local anesthetic infiltration technique in postoperative nausea and vomiting after tonsillectomy in children: A randomized double-blind clinical trial. International journal of pediatric otorhinolaryngology, 2017, Volume: 92 Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Anesthesia, Local;	2017
Is celecoxib a useful adjunct in the treatment of post-tonsillectomy pain in the adult population? A randomised, double-blind, placebo-controlled study. The Journal of laryngology and otology, 2017, Volume: 131, Issue:S1 Topics: Acetaminophen; Adolescent; Adult; Analgesics; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind M	2017
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double	2009
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double	2009
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double	2009
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double	2009
Comparison of analgesic effect of tramadol alone and a combination of tramadol and paracetamol in day-care laparoscopic surgery. European journal of anaesthesiology, 2009, Volume: 26, Issue:6 Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Blood Pressure; Doub	2009
Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial. European journal of anaesthesiology, 2009, Volume: 26, Issue:8 Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste	2009
Dexamethasone decreases oxycodone consumption following osteotomy of the first metatarsal bone: a randomized controlled trial in day surgery. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:3 Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid;	2010
Brief report: improved pain relief using intermittent bupivacaine injections at the donor site after breast reconstruction with deep inferior epigastric perforator flap. Anesthesia and analgesia, 2010, Apr-01, Volume: 110, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local	2010
The analgesic efficacy of subarachnoid morphine in comparison with ultrasound-guided transversus abdominis plane block after cesarean delivery: a randomized controlled trial. Anesthesia and analgesia, 2010, Volume: 111, Issue:2 Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesic	2010
Effects of preemptive analgesia in laparoscopic cholecystectomy: a double-blind randomized controlled trial. Surgical endoscopy, 2011, Volume: 25, Issue:1 Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic;	2011
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. Minerva anestesiologica, 2010, Volume: 76, Issue:10 Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra	2010
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. Minerva anestesiologica, 2010, Volume: 76, Issue:10 Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra	2010
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. Minerva anestesiologica, 2010, Volume: 76, Issue:10 Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra	2010
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. Minerva anestesiologica, 2010, Volume: 76, Issue:10 Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra	2010
Nicotine nasal spray as an adjuvant analgesic for third molar surgery. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:5 Topics: Acetaminophen; Administration, Intranasal; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic;	2011
The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children. Journal of clinical anesthesia, 2011, Volume: 23, Issue:1 Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia,	2011
The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy. Archives of gynecology and obstetrics, 2011, Volume: 284, Issue:6 Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Femal	2011
[Tonsillotomy and adenotonsillectomy in childhood. Study on postoperative pain therapy]. Der Anaesthesist, 2011, Volume: 60, Issue:7 Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics,	2011
Target-controlled dosing of remifentanil during cardiac surgery reduces postoperative hyperalgesia. Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:6 Topics: Acetaminophen; Aged; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Blood Pressur	2011
A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy. Anaesthesia, 2011, Volume: 66, Issue:10* Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; An	2011
The effect of paracetamol on postoperative nausea and vomiting during the first 24 h after strabismus surgery: a prospective, randomised, double-blind study. European journal of anaesthesiology, 2011, Volume: 28, Issue:12 Topics: Acetaminophen; Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Humans; Infusions,	2011
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study. Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot	2012
Long-term quality of sleep after remifentanil-based anaesthesia: a randomized controlled trial. British journal of anaesthesia, 2013, Volume: 110, Issue:2 Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Intravenous; Anesthetics, In	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. Journal of neurosurgical anesthesiology, 2013, Volume: 25, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi	2013
Perioperative gastric emptying is not a predictor of early postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Anesthesia and analgesia, 2002, Volume: 95, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Area Under Curve; Cholecystectomy, Laparoscopi	2002
Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgery. Anesthesiology, 2002, Volume: 97, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; An	2002
Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. Anesthesia and analgesia, 2002, Volume: 95, Issue:5 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; D	2002
[Postoperative comfort in pediatric outpatient tonsillectomy]. Annales francaises d'anesthesie et de reanimation, 2002, Volume: 21, Issue:10 Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi	2002
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. Anesthesia and analgesia, 2003, Volume: 96, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi	2003
Does ketamine or magnesium affect posttonsillectomy pain in children? Paediatric anaesthesia, 2003, Volume: 13, Issue:5 Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child	2003
Dose response study of caudal neostigmine for postoperative analgesia in paediatric patients undergoing genitourinary surgery. Paediatric anaesthesia, 2003, Volume: 13, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Caudal; Child; Child, Preschool; Cholinesterase	2003
Dolasetron for the prevention of postoperative vomiting in children undergoing strabismus surgery. Paediatric anaesthesia, 2003, Volume: 13, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, General; Antiemetics; Child; Child, Preschool;	2003
Comparison of oral dolasetron and ondansetron in the prophylaxis of postoperative nausea and vomiting in children. European journal of anaesthesiology, 2003, Volume: 20, Issue:10 Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Antiemeti	2003
Sub-Tenon's block reduces both intraoperative and postoperative analgesia requirement in vitreo-retinal surgery under general anaesthesia. European journal of anaesthesiology, 2003, Volume: 20, Issue:12 Topics: Acetaminophen; Aged; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General;	2003
Postoperative epidural morphine for postpartum tubal ligation analgesia. Anesthesia and analgesia, 2005, Volume: 101, Issue:3 Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesic	2005
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:3 Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar	2005
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:3 Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar	2005
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:3 Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar	2005
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. Journal of cardiothoracic and vascular anesthesia, 2005, Volume: 19, Issue:3 Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar	2005
Analgesic efficacy of diclofenac in combination with morphine and paracetamol after mastectomy and immediate breast reconstruction. Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:9 Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents,	2005
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. Journal of endourology, 2005, Volume: 19, Issue:10 Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine	2005
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. Journal of endourology, 2005, Volume: 19, Issue:10 Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine	2005
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. Journal of endourology, 2005, Volume: 19, Issue:10 Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine	2005
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. Journal of endourology, 2005, Volume: 19, Issue:10 Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine	2005
Etoricoxib pre-medication for post-operative pain after laparoscopic cholecystectomy. Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:6 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Ana	2006
Acetaminophen is highly effective in pain treatment after endoscopic sinus surgery. The Laryngoscope, 2006, Volume: 116, Issue:12 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chronic Disease; Double-Blind Method; Endoscopy; Fem	2006
Intravenous paracetamol as adjunctive treatment for postoperative pain after cardiac surgery: a double blind randomized controlled trial. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2007, Volume: 32, Issue:3 Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; Chem	2007
Effect of paracetamol and coxib with or without dexamethasone after laparoscopic cholecystectomy. Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:5 Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cholecystectom	2008
Oral granisetron for strabismus surgery in children. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:1 Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Antiemetics;	1999
Ondansetron with propofol reduces the incidence of emesis in children following tonsillectomy. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:4 Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Anesthetics, Intraveno	1999
Delayed postoperative gastric emptying following intrathecal morphine and intrathecal bupivacaine. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:6 Topics: Absorption; Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid;	1999
The analgesic effect of preoperative administration of propacetamol, tenoxicam or a mixture of both in arthroscopic, outpatient knee surgery. Acta anaesthesiologica Belgica, 1999, Volume: 50, Issue:2 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; An	1999
Tramadol suppositories are less suitable for post-operative pain relief than rectal acetaminophen/codeine. European journal of anaesthesiology, 1999, Volume: 16, Issue:7 Topics: Acetaminophen; Administration, Rectal; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Co	1999
Prophylactically-administered rectal acetaminophen does not reduce postoperative opioid requirements in infants and small children undergoing elective cleft palate repair. Anesthesia and analgesia, 2001, Volume: 92, Issue:4 Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Cle	2001
Patient-controlled epidural analgesia versus continuous epidural analgesia after total knee arthroplasty. Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:4 Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesi	2001
Intravenous tramadol compared to propacetamol for postoperative analgesia following thyroidectomy. Acta anaesthesiologica Belgica, 2001, Volume: 52, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Double-Blind Method; Female;	2001
Effect of peri- and postoperative epidural anaesthesia on pain and gastrointestinal function after abdominal hysterectomy. British journal of anaesthesia, 2001, Volume: 87, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Ep	2001

Article	Year
Oral versus intravenous acetaminophen for perioperative pain management in adult patients undergoing non-cardiac surgery: A quantile segmented regression analysis. Journal of clinical anesthesia, 2023, Volume: 90 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Middle Aged; Narcotics;	2023
Remifentanil for abdominal surgery is associated with unexpectedly unfavorable outcomes. Pain, 2020, Volume: 161, Issue:2 Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal;	2020
Effect of scheduled intravenous acetaminophen on postoperative nausea and vomiting in patients undergoing laparoscopic gynecologic surgery. Journal of anesthesia, 2020, Volume: 34, Issue:4 Topics: Acetaminophen; Antiemetics; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; La	2020
Improved analgesia and reduced post-operative nausea and vomiting after implementation of an enhanced recovery after surgery (ERAS) pathway for total mastectomy. BMC anesthesiology, 2018, 04-16, Volume: 18, Issue:1 Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Conduction; Antiemetics;	2018
Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery. European journal of ophthalmology, 2019, Volume: 29, Issue:6 Topics: Acetaminophen; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anti-Anxiety Agen	2019
Perioperative pain and post-operative nausea and vomiting (PONV) management after day-case surgery: The SFAR-OPERA national study. Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:3 Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid;	2019
Acetaminophen to reduce postoperative nausea and vomiting in patients undergoing strabismus surgery. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2019, Volume: 31, Issue:2 Topics: Acetaminophen; Administration, Intravenous; Humans; Postoperative Nausea and Vomiting; Prospective S	2019
Letter to the editor. Pain, 2014, Volume: 155, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Male; Postoperative Nausea and Vomiting	2014
Response to letter to the editor. Pain, 2014, Volume: 155, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Male; Postoperative Nausea and Vomiting	2014
Cost-effectiveness of intravenous acetaminophen for pediatric tonsillectomy. Paediatric anaesthesia, 2014, Volume: 24, Issue:5 Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Cost-Benefit Analysis; Decision	2014
Utilization of a Preemptive, Multimodal Analgesic Regimen in Adult Ambulatory Septoplasty Patients: A Quality Improvement Project. ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses, 2015,Autumn, Volume: 33, Issue:4 Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Analgesics; Celecoxib; Cyclohexanecarb	2015
Effectiveness of postoperative intravenous acetaminophen (Acelio) after gastrectomy: A propensity score-matched analysis. Medicine, 2016, Volume: 95, Issue:44 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Female;	2016
[Postoperative inconveniences after breast cancer surgery]. Ugeskrift for laeger, 2008, Jun-02, Volume: 170, Issue:23 Topics: Acetaminophen; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyc	2008
A randomized clinical trial of the efficacy of scheduled dosing of acetaminophen and hydrocodone for the management of postoperative pain in children after tonsillectomy. The Clinical journal of pain, 2011, Volume: 27, Issue:1 Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Humans; Hydrocodo	2011
Analgesia in fast-track paediatric cardiac patients. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011, Volume: 40, Issue:3 Topics: Acetaminophen; Adolescent; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Cardiac Sur	2011
Need for improved treatment of postoperative pain. Danish medical journal, 2012, Volume: 59, Issue:4 Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; A	2012
An evaluation of pain and postoperative nausea and vomiting following the introduction of guidelines for tonsillectomy. Paediatric anaesthesia, 2005, Volume: 15, Issue:8 Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Ant	2005
Post-dural headache associated with thoracic paravertebral blocks. Journal of clinical anesthesia, 2006, Volume: 18, Issue:5 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St	2006
Daycase laparoscopic cholecystectomy: a prospective study of post-discharge pain, analgesic and antiemetic requirements. Irish journal of medical science, 2008, Volume: 177, Issue:2 Topics: Acetaminophen; Aftercare; Ambulatory Surgical Procedures; Analgesics; Cholecystectomy, Laparoscopic;	2008
Post tonsillectomy pain. Paediatric anaesthesia, 1999, Volume: 9, Issue:3 Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, No	1999
Prevention of postoperative vomiting with granisetron in paediatric patients with and without a history of motion sickness. Paediatric anaesthesia, 2000, Volume: 10, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Child; Disease Susceptibil	2000
Analgesia following paediatric day-surgical orchidopexy and herniotomy. Paediatric anaesthesia, 2000, Volume: 10, Issue:6 Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Child; C	2000
A comparison of post-operative morbidity following outpatient dental care under general anaesthesia in paediatric patients with and without disabilities. International journal of paediatric dentistry, 2000, Volume: 10, Issue:2 Topics: Acetaminophen; Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia	2000

acetaminophen and Emesis, Postoperative

Research Excerpts

Research

Studies (93)

Authors

Clinical Trials (46)

Trial Overview

Trial Outcomes

Intensive Care Delirium Screening Checklist (ICDSC)

Number of Participants With Readmission to the Hospital

Postoperative Pain Intensity

Time to Ambulation

Time to Bowel Movement

Time to Hospital Discharge

Time to Oral Intake

Time to Readiness for Discharge From Post Anesthesia Care Unit (PACU)

Patient Satisfaction

Post-operative Emesis

Post-operative Nausea

SF-12 Health Survey

Total Post-operative Narcotic Consumption

Hours Until Discharge Readiness

Time to Adequate Analgesia

Time Until Ambulation at Least 30 Meters

Time Until Independence From Intravenous Analgesics of at Least 12 Hours

Time Until Timed Up and Go Test Achieved

Opioid Consumption

Pain Level

Number of Grid Points With Change of Sensation to Pinprick After Blockade

Quadriceps Muscle Strength in Kilogram-force (Kgf)

Total Opioid Consumption at 24 Hours Post-block

Post-operative Pain Scores Using the Numeric Pain Scoring System (NS)

Number of Hospital Days Until Discharge Criteria Are Met

Number of Participants With Adverse Events Related to Adductor Canal Nerve Block Catheter

Number of Participants With Bleeding Complications at Adductor Canal Nerve Block Catheter Site

Morphine Equivalents

Physical Therapy Ambulation Distance

Range of Motion

Range of Motion at 3 and 6 Week Follow up

Visual Analog Score for Pain

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

Anterior Chamber Cell Grade

Pain Visual Analogue Scale (VAS) Score

Anterior Chamber Cell Grade

Pain Visual Analogue Scale (VAS) Score

Opioid Consumption (Morphine Equivalents)

Quality of Recovery 40 Score

Reviews

Trials

Other Studies