acetaminophen has been researched along with Drug-Induced Stevens Johnson Syndrome in 33 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the association between 2 mood stabilizers (carbamazepine and valproate) and other medications (including other anticonvulsants) and the risks of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) among patients with bipolar disorder." | 7.74 | The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. ( Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ, 2008) |
| "Acetaminophen (paracetamol) is a widely used analgesic and antipyretic." | 6.72 | A review of published cases of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with the use of acetaminophen. ( Milosavljević, JZ; Milosavljević, MN; Pejčić, AV, 2021) |
| "Acetaminophen is an over-the-counter drug used worldwide to treat pain and reduce fever." | 5.48 | Is acetaminophen associated with a risk of Stevens-Johnson syndrome and toxic epidermal necrolysis? Analysis of the French Pharmacovigilance Database. ( Gras-Champel, V; Guy, C; Jean-Pastor, MJ; Lebrun-Vignes, B; Zenut, M, 2018) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse mucocutaneous reactions to certain drugs." | 5.42 | Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine. ( Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH, 2015) |
| " There are few cases reports of "Stevens-Johnson syndrome/Toxic Epidermal Necrolysis" associated with acetaminophen in the literature." | 3.83 | A Case of Toxic Epidermal Necrolysis Secondary to Acetaminophen in a Child. ( Alcalá, PJ; Cuello, JD; Pena, MÁ; Pérez, S; Reig, R; Zapater, P; Zazo, MC, 2016) |
| " Although a lymphocyte stimulation test was positive only for acetaminophen, he took other agents including carbamazepine for his depression." | 3.76 | Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7. ( Honma, M; Iinuma, S; Iizuka, H; Ishida-Yamamoto, A; Komatsu, S; Shibuya, T; Takahashi, I; Tobisawa, S, 2010) |
| "This study investigated the association between 2 mood stabilizers (carbamazepine and valproate) and other medications (including other anticonvulsants) and the risks of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) among patients with bipolar disorder." | 3.74 | The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study. ( Chang, CJ; Chao, PF; Gau, CS; Gau, SS; Lin, YJ, 2008) |
| "Toxic epidermal necrolysis with epidermal shedding over almost the entire body occurred in a patient with classical rheumatoid arthritis treated with sulindac, penicillamine and a combination analgesic containing paracetamol and chlormezanone." | 3.67 | Toxic epidermal necrolysis with extensive mucosal erosions of the gastrointestinal and respiratory tracts. ( Ahlmén, M; Fagerberg, B; Roupe, G; Suurküla, M, 1986) |
| "Acetaminophen (paracetamol) is a widely used analgesic and antipyretic." | 2.72 | A review of published cases of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with the use of acetaminophen. ( Milosavljević, JZ; Milosavljević, MN; Pejčić, AV, 2021) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are fatal adverse skin reactions characterized by high fever, epidermal detachment, and mucositis." | 1.62 | A pediatric case of Stevens-Johnson syndrome with acute liver failure, resulting in liver transplantation. ( Aihara, M; Honda, Y; Kumamoto, T; Saito, S; Takamura, N; Totsuka, M; Watanabe, T; Watanabe, Y; Yamanaka, S; Yoneda, M, 2021) |
| "Acetaminophen is an over-the-counter drug used worldwide to treat pain and reduce fever." | 1.48 | Is acetaminophen associated with a risk of Stevens-Johnson syndrome and toxic epidermal necrolysis? Analysis of the French Pharmacovigilance Database. ( Gras-Champel, V; Guy, C; Jean-Pastor, MJ; Lebrun-Vignes, B; Zenut, M, 2018) |
| "She had poorly controlled ulcerative colitis and was treated with high doses of prednisolone, infliximab, acetaminophen and lansoprazole." | 1.43 | Toxic epidermal necrolysis caused by acetaminophen featuring almost 100% skin detachment: Acetaminophen is associated with a risk of severe cutaneous adverse reactions. ( Aruga, T; Fukuda, K; Kamiyama, T; Kobayashi, K; Miyake, Y; Sasaki, S; Sueki, H; Watanabe, H, 2016) |
| " In this research, we have explored the feasibility of retrospectively mapping population-level adverse events from the FDA Adverse Event Reporting System (FAERS) to chemical and biological databases to identify drug safety signals and the underlying molecular mechanisms." | 1.43 | Improving drug safety with a systems pharmacology approach. ( Bojunga, N; Lesko, LJ; Schotland, P; Trame, MN; Zien, A, 2016) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse mucocutaneous reactions to certain drugs." | 1.42 | Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine. ( Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH, 2015) |
| "Steven Johnson Syndrome and Toxic Epidermal Necrolysis are rare but severe form of hypersensitivity inflammatory reactions to multiple offending agents including drugs." | 1.38 | Acetaminophen induced Steven Johnson syndrome-toxic epidermal necrolysis overlap. ( Hussain, SA; Khawaja, A; Shahab, A, 2012) |
| "To report a case of toxic epidermal necrolysis (TEN) associated with acetaminophen ingestion." | 1.31 | Toxic epidermal necrolysis associated with acetaminophen ingestion. ( Ben-Amitai, D; Garty, BZ; Halevi, A, 2000) |
| "We report a case of toxic epidermal necrolysis-type drug eruption." | 1.31 | A case of toxic epidermal necrolysis-type drug eruption induced by oral lysozyme chloride. ( Asahi, M; Kobayashi, M; Yamamoto, O; Yasuda, H, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 17 (51.52) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| Dégboé, B | 1 |
| Koudoukpo, C | 1 |
| Almeida, CD | 1 |
| Kouassi, A | 1 |
| Nguessie, C | 1 |
| Akpadjan, F | 1 |
| Adégbidi, H | 1 |
| Atadokpèdé, F | 1 |
| Liu, JB | 1 |
| Hao, D | 1 |
| Saito, Y | 2 |
| Nakamura, R | 2 |
| Jongkhajornpong, P | 1 |
| Ueta, M | 2 |
| Lekhanont, K | 1 |
| Puangsricharern, V | 1 |
| Prabhasawat, P | 1 |
| Chantaren, P | 1 |
| Pisuchpen, P | 1 |
| Kinoshita, S | 2 |
| Liccioli, G | 1 |
| Filippeschi, C | 1 |
| Giovannini, M | 1 |
| Capone, M | 1 |
| Oranges, T | 1 |
| Barni, S | 1 |
| Sarti, L | 1 |
| Parronchi, P | 1 |
| Mori, F | 1 |
| Totsuka, M | 1 |
| Watanabe, T | 1 |
| Takamura, N | 1 |
| Watanabe, Y | 1 |
| Kumamoto, T | 1 |
| Honda, Y | 1 |
| Yoneda, M | 1 |
| Saito, S | 1 |
| Yamanaka, S | 1 |
| Aihara, M | 2 |
| Milosavljević, MN | 1 |
| Pejčić, AV | 1 |
| Milosavljević, JZ | 1 |
| Lebrun-Vignes, B | 1 |
| Guy, C | 1 |
| Jean-Pastor, MJ | 1 |
| Gras-Champel, V | 1 |
| Zenut, M | 1 |
| Kuehn, BM | 1 |
| Biswal, S | 1 |
| Sahoo, SS | 1 |
| Kaniwa, N | 1 |
| Sotozono, C | 1 |
| Tokunaga, K | 1 |
| Sawai, H | 1 |
| Miyadera, H | 1 |
| Sugiyama, E | 1 |
| Maekawa, K | 1 |
| Nagato, M | 1 |
| Matsunaga, K | 1 |
| Takahashi, Y | 1 |
| Furuya, H | 1 |
| Muramatsu, M | 1 |
| Ikezawa, Z | 1 |
| Ladizinski, B | 1 |
| Sankey, C | 1 |
| Slim, R | 1 |
| Fathallah, N | 1 |
| Aounallah, A | 1 |
| Ksiaa, M | 1 |
| Sriha, B | 1 |
| Nouira, R | 1 |
| Ben Salem, C | 1 |
| Park, HJ | 1 |
| Kim, SR | 1 |
| Leem, DW | 1 |
| Moon, IJ | 1 |
| Koh, BS | 1 |
| Park, KH | 1 |
| Park, JW | 1 |
| Lee, JH | 1 |
| Harimoto, N | 1 |
| Wang, H | 1 |
| Ikegami, T | 1 |
| Takeishi, K | 1 |
| Itoh, S | 1 |
| Yamashita, YI | 1 |
| Yoshizumi, T | 1 |
| Aishima, S | 1 |
| Shirabe, K | 1 |
| Oda, Y | 1 |
| Maehara, Y | 1 |
| Watanabe, H | 1 |
| Kamiyama, T | 1 |
| Sasaki, S | 1 |
| Kobayashi, K | 1 |
| Fukuda, K | 1 |
| Miyake, Y | 1 |
| Aruga, T | 1 |
| Sueki, H | 1 |
| Pena, MÁ | 1 |
| Pérez, S | 1 |
| Zazo, MC | 1 |
| Alcalá, PJ | 1 |
| Cuello, JD | 1 |
| Zapater, P | 1 |
| Reig, R | 1 |
| Schotland, P | 1 |
| Bojunga, N | 1 |
| Zien, A | 1 |
| Trame, MN | 1 |
| Lesko, LJ | 1 |
| Gau, SS | 1 |
| Chao, PF | 1 |
| Lin, YJ | 1 |
| Chang, CJ | 1 |
| Gau, CS | 1 |
| Sahagún Flores, JE | 1 |
| Soto Ortiz, JA | 1 |
| Tovar Méndez, CE | 1 |
| Cárdenas Ochoa, EC | 1 |
| Hernández Flores, G | 1 |
| Honma, M | 1 |
| Tobisawa, S | 1 |
| Iinuma, S | 1 |
| Shibuya, T | 1 |
| Komatsu, S | 1 |
| Takahashi, I | 1 |
| Ishida-Yamamoto, A | 1 |
| Iizuka, H | 1 |
| Reese, D | 1 |
| Henning, JS | 1 |
| Rockers, K | 1 |
| Ladd, D | 1 |
| Gilson, R | 1 |
| Khawaja, A | 1 |
| Shahab, A | 1 |
| Hussain, SA | 1 |
| Selbst, SM | 1 |
| Osterhoudt, K | 1 |
| Halevi, A | 1 |
| Ben-Amitai, D | 1 |
| Garty, BZ | 1 |
| Kobayashi, M | 1 |
| Yamamoto, O | 1 |
| Yasuda, H | 1 |
| Asahi, M | 1 |
| Robak, E | 1 |
| Robak, T | 1 |
| Góra-Tybor, J | 1 |
| Chojnowski, K | 1 |
| Strzelecka, B | 1 |
| Waszczykowska, E | 1 |
| Sysa-Jedrzejowska, A | 1 |
| Cohen, AD | 1 |
| Cagnano, E | 1 |
| Halevy, S | 1 |
| Arturson, G | 1 |
| Hedlund, A | 1 |
| Andersson, C | 1 |
| Jordeby-Jönsson, A | 1 |
| Martinsson, EL | 1 |
| Cugurra, F | 1 |
| Roupe, G | 1 |
| Ahlmén, M | 1 |
| Fagerberg, B | 1 |
| Suurküla, M | 1 |
| Hunter, JA | 1 |
| Davison, AM | 1 |
3 reviews available for acetaminophen and Drug-Induced Stevens Johnson Syndrome
| Article | Year |
|---|---|
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy].
Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbam | 2019 |
A review of published cases of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with the use of acetaminophen.
Topics: Acetaminophen; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Risk Factors; Stevens-Johnson | 2021 |
Cyclosporine for SJS/TEN: a case series and review of the literature.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Infective Agents; Anticonvulsants; Cyclosporine | 2011 |
30 other studies available for acetaminophen and Drug-Induced Stevens Johnson Syndrome
| Article | Year |
|---|---|
Severe Cutaneous Adverse Drug Reactions in Children: Epidemiological, Clinical and Etiological Aspects in Dermatology-Venereology Unit at National and Teaching Hospital of Cotonou.
Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Benin; Child; Dermato | 2022 |
[Acetaminophen induced Stevens-Johnson syndrome in a child].
Topics: Acetaminophen; Child; Humans; Stevens-Johnson Syndrome | 2019 |
Association of HLA polymorphisms and acetaminophen-related Steven-Johnson syndrome with severe ocular complications in Thai population.
Topics: Acetaminophen; Case-Control Studies; Genetic Predisposition to Disease; HLA-A Antigens; HLA-B Antige | 2022 |
Mycoplasma pneumoniae-associated mucocutaneous disease in children: A case series with allergy workup in a tertiary care paediatric hospital.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child; Child, Preschool; | 2021 |
A pediatric case of Stevens-Johnson syndrome with acute liver failure, resulting in liver transplantation.
Topics: Acetaminophen; Adolescent; Child; Female; Humans; Liver Failure, Acute; Liver Transplantation; Skin; | 2021 |
Is acetaminophen associated with a risk of Stevens-Johnson syndrome and toxic epidermal necrolysis? Analysis of the French Pharmacovigilance Database.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Non-Narcotic; Chi | 2018 |
FDA: Acetaminophen may trigger serious skin problems.
Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcotic; Humans; Stevens-Jo | 2013 |
Paracetamol induced Stevens-Johnson syndrome--toxic epidermal necrolysis overlap syndrome.
Topics: Acetaminophen; Antipyretics; Child; Female; Fever; Humans; Stevens-Johnson Syndrome | 2014 |
Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studie | 2014 |
A topical matter: toxic epidermal necrolysis.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents; Anticonvulsants; Antiemetics; Antineopl | 2014 |
Paracetamol-induced Stevens Johnson syndrome and cholestatic hepatitis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Drug Eruptio | 2015 |
Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine.
Topics: Acetaminophen; Acetazolamide; Adult; Aged; Aged, 80 and over; Alleles; Allopurinol; Anti-Bacterial A | 2015 |
Education and imaging. Hepatology: Rare Stevens-Johnson syndrome and vanishing bile duct syndrome induced by acetaminophen, requiring liver transplantation.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Bile Ducts, Intrahepatic; Cholestasis; Dilat | 2015 |
Toxic epidermal necrolysis caused by acetaminophen featuring almost 100% skin detachment: Acetaminophen is associated with a risk of severe cutaneous adverse reactions.
Topics: Acetaminophen; Adult; Colitis, Ulcerative; Female; Humans; Prednisolone; Stevens-Johnson Syndrome | 2016 |
A Case of Toxic Epidermal Necrolysis Secondary to Acetaminophen in a Child.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child, Preschool; Humans; Male; Stevens-Johnson Syndrome | 2016 |
Improving drug safety with a systems pharmacology approach.
Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcotic; Anticonvulsants; C | 2016 |
The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study.
Topics: Acetaminophen; Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Contr | 2008 |
[Stevens-Johnson syndrome plus intrahepatic cholestasis caused by clindamycin or chlorpheniramine].
Topics: Acetaminophen; Betamethasone; Bronchitis; Chlorpheniramine; Cholestasis, Intrahepatic; Clindamycin; | 2009 |
Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7.
Topics: Acetaminophen; Acute Generalized Exanthematous Pustulosis; Adult; Anti-Inflammatory Agents; Antidepr | 2010 |
Acetaminophen induced Steven Johnson syndrome-toxic epidermal necrolysis overlap.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Diagnosis, Differential; Female; Humans; Stevens-Joh | 2012 |
Pediatric emergency medicine: legal briefs.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Appendicitis; | 2012 |
Toxic epidermal necrolysis associated with acetaminophen ingestion.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Fever; Humans; Stevens-Johnson Syndrome | 2000 |
A case of toxic epidermal necrolysis-type drug eruption induced by oral lysozyme chloride.
Topics: Acetaminophen; Administration, Oral; Adult; Anti-Inflammatory Agents; Betamethasone; Biopsy, Needle; | 2000 |
Toxic epidermal necrolysis in a patient with severe aplastic anemia treated with cyclosporin A and G-CSF.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anemia, Aplastic; Cyclosporine; Granulocyte Colony-S | 2001 |
Acute generalized exanthematous pustulosis mimicking toxic epidermal necrolysis.
Topics: Acetaminophen; Acute Disease; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Cefuroxime; Cephalo | 2001 |
[Lobac caused a life-threatening burn-like skin injury].
Topics: Acetaminophen; Adult; Burns, Chemical; Humans; Male; Stevens-Johnson Syndrome | 1991 |
[The Lobac overview: little risk of adverse effects. Effects on skin and liver are the most common and the most severe].
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Chlormezanone; Drug Combinations; Humans; Ris | 1991 |
[XXVIII. Antipyretic and antineuralgic agents for grown-ups and little-ones].
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Infant, Ne | 1989 |
Toxic epidermal necrolysis with extensive mucosal erosions of the gastrointestinal and respiratory tracts.
Topics: Acetaminophen; Arthritis, Rheumatoid; Biopsy; Chlormezanone; Drug Combinations; Female; Humans; Inte | 1986 |
Toxic epidermal necrolysis associated with pentazocine therapy and severe reversible renal failure.
Topics: Acetaminophen; Acute Kidney Injury; Blood Cells; Blood Pressure; Chlorpheniramine; Cloxacillin; Dext | 1973 |