acetaminophen has been researched along with Down Syndrome in 3 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Excerpt | Relevance | Reference |
---|---|---|
"In this study we evaluated subjects with Down's syndrome for the possibility that direct or indirect gene dosage effects of trisomy 21 alter the fate of acetaminophen." | 1.28 | Noninvasive determination of acetaminophen disposition in Down's syndrome. ( Cooke, RE; Corcoran, GB; Griener, JC; Msall, ME, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mian, P | 1 |
Valkenburg, AJ | 1 |
Allegaert, K | 1 |
Koch, BCP | 1 |
Breatnach, CV | 1 |
Knibbe, CAJ | 1 |
Tibboel, D | 1 |
Krekels, EHJ | 1 |
de Knegt, NC | 1 |
Evenhuis, HM | 1 |
Lobbezoo, F | 1 |
Schuengel, C | 1 |
Scherder, EJ | 1 |
Griener, JC | 1 |
Msall, ME | 1 |
Cooke, RE | 1 |
Corcoran, GB | 1 |
3 other studies available for acetaminophen and Down Syndrome
Article | Year |
---|---|
Population Pharmacokinetic Modeling of Acetaminophen and Metabolites in Children After Cardiac Surgery With Cardiopulmonary Bypass.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Biological Variation, Populati | 2019 |
Does format matter for comprehension of a facial affective scale and a numeric scale for pain by adults with Down syndrome?
Topics: Acetaminophen; Adult; Affect; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cog | 2013 |
Noninvasive determination of acetaminophen disposition in Down's syndrome.
Topics: Acetaminophen; Administration, Oral; Age Factors; Down Syndrome; Female; Humans; Male; Sex Factors | 1990 |