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acetaminophen and Disseminated Intravascular Coagulation

acetaminophen has been researched along with Disseminated Intravascular Coagulation in 11 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.

Research Excerpts

ExcerptRelevanceReference
"Sepsis is a heterogeneous clinical syndrome that is complicated commonly by acute kidney injury (sepsis-AKI)."2.66The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury. ( Kerchberger, VE; Ware, LB, 2020)
"Acetaminophen or paracetamol, a commonly used over-the-counter analgesic, is known to elicit severe adverse reactions when taken in overdose, chronically at therapeutic dosage or, sporadically, following single assumptions of a therapeutic dose."1.39Possible fatal acetaminophen intoxication with atypical clinical presentation. ( Carbone, A; Chiarotti, M; d'Aloja, E; De-Giorgio, F; Lodise, M; Valerio, L, 2013)
"In addition to hepatic dysfunction, renal failure and disseminated intravascular coagulopathy, we should pay attention to various symptoms like in this case when treating for a acetaminophen poisoning."1.33[Case report of repeated acetaminophen overdosing with various symptoms]. ( Inagawa, H; Ishida, J; Kojima, N; Machida, M; Okada, Y; Terada, T, 2006)
"Maternal disseminated intravascular coagulation (DIC) may have been related to maternal acetaminophen-induced liver disease alone or to a combination of liver disease and the presence of a dead fetus."1.27Acetaminophen overdose with fetal demise. ( Akhter, JE; Cary, PL; Haibach, H; Hoffmann, MF; Muscato, MS, 1984)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Kerchberger, VE1
Ware, LB1
De-Giorgio, F1
Lodise, M1
Chiarotti, M1
d'Aloja, E1
Carbone, A1
Valerio, L1
Kojima, N1
Ishida, J1
Inagawa, H1
Okada, Y1
Machida, M1
Terada, T1
Haibach, H1
Akhter, JE1
Muscato, MS1
Cary, PL1
Hoffmann, MF1
Riggs, JE1
Schochet, SS1
Parmar, JP1
Washio, M1
Inoue, N1
Köster, M1
Wege, T1
Ganzemüller, C1
Lengfelder, W1
Langley, PG1
Forbes, A1
Hughes, RD1
Williams, R4
Read, RB1
Tredger, JM1
Clark, R2
Rake, MO1
Flute, PT1
Gazzard, BG1
Borirakchanyavat, V1

Reviews

1 review available for acetaminophen and Disseminated Intravascular Coagulation

ArticleYear
The Role of Circulating Cell-Free Hemoglobin in Sepsis-Associated Acute Kidney Injury.
    Seminars in nephrology, 2020, Volume: 40, Issue:2

    Topics: Acetaminophen; Acute Kidney Injury; Anemia, Sickle Cell; Animals; Coronary Artery Bypass; Disseminat

2020

Trials

1 trial available for acetaminophen and Disseminated Intravascular Coagulation

ArticleYear
A controlled trial of heparin therapy in the coagulation defect of paracetamol-induced hepatic necrosis.
    Gut, 1974, Volume: 15, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Blood Coagulation Disorders; Blood Transfusion; Chemical and Drug

1974

Other Studies

9 other studies available for acetaminophen and Disseminated Intravascular Coagulation

ArticleYear
Possible fatal acetaminophen intoxication with atypical clinical presentation.
    Journal of forensic sciences, 2013, Volume: 58, Issue:5

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Disseminated Intravascular Coagulation

2013
[Case report of repeated acetaminophen overdosing with various symptoms].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2006, Volume: 19, Issue:2

    Topics: Abdominal Pain; Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Disseminated Intravasc

2006
Acetaminophen overdose with fetal demise.
    American journal of clinical pathology, 1984, Volume: 82, Issue:2

    Topics: Acetaminophen; Adult; Disseminated Intravascular Coagulation; Female; Fetal Death; Humans; Liver; Pr

1984
Rhabdomyolysis with acute renal failure and disseminated intravascular coagulation: association with acetaminophen and ethanol.
    Military medicine, 1996, Volume: 161, Issue:11

    Topics: Acetaminophen; Acute Kidney Injury; Alcohol Drinking; Disseminated Intravascular Coagulation; Ethano

1996
The risk factors of death from the acetaminophen poisoning with antipyretic-analgesic drugs in Japan.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1997, Volume: 88, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Disseminated In

1997
[44-year-old patient with thrombocytopenia, multiple organ failure and disseminated intravascular coagulation caused by drug poisoning with paracetamol, metamizole, benzodiazepines and alcohol in attempted suicide].
    Der Internist, 2001, Volume: 42, Issue:6

    Topics: Acetaminophen; Adult; Alcoholic Intoxication; Bromazepam; Critical Care; Dipyrone; Disseminated Intr

2001
Thrombin-antithrombin III complex in fulminant hepatic failure: evidence for disseminated intravascular coagulation and relationship to outcome.
    European journal of clinical investigation, 1990, Volume: 20, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Antithrombin III; Disseminated Intravascular Coagulation; Drug Ove

1990
Analysis of factors responsible for continuing mortality after paracetamol overdose.
    Human toxicology, 1986, Volume: 5, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Alcoholism; Antidotes; Dextropropoxyphene; Disseminated I

1986
Coagulation abnormalities in acute liver failure; pathogenetic and therapeutic implications.
    Scandinavian journal of gastroenterology. Supplement, 1973, Volume: 19

    Topics: Acetaminophen; Acute Disease; Bilirubin; Biopsy; Blood Coagulation Disorders; Blood Coagulation Test

1973