Page last updated: 2024-10-22

acetaminophen and Diseases of Endocrine System

acetaminophen has been researched along with Diseases of Endocrine System in 1 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Ruffolo, LI1
Jackson, KM1
Juviler, P1
Kaur, R1
Chennell, T1
Glover, DM1
Linehan, DC1
Moalem, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Controlled Trial for Postoperative opt-in Narcotic Treatment in Outpatient Endocrine Surgery[NCT04710069]102 participants (Actual)Interventional2020-06-26Completed
Optimization of Opioid Discharge Prescriptions Following Thyroid and Parathyroid Surgeries[NCT04955444]240 participants (Actual)Interventional2021-06-14Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

New Opioid Discharge Prescriptions

Proportion of patients who receive new opioid discharge prescriptions at discharge following a thyroidectomy or parathyroidectomy procedure. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group128
Post-implementation Group28

New Opioid Prescriptions From the Surgeon's Office Within 7 Days of Surgery

Proportion of thyroidectomy and parathyroidectomy postoperative patients who receive new opioid prescriptions from the surgeon's office within 7 days of surgery including discharge prescriptions. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 7 days

InterventionParticipants (Count of Participants)
Historical Control Group0
Post-implementation Group0

Opioid Discharge Prescriptions Exceeding 112.5 Oral Morphine Milligram Equivalents (MMEs)

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding the recommended dose of 112.5 oral MMEs (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group52
Post-implementation Group8

Opioid Discharge Prescriptions Exceeding 5 Days

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding 5 days of therapy (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group27
Post-implementation Group5

Opioid Prescriptions Exceeding 50 Oral MMEs/Day When New Discharge Prescriptions Are Added to Existing Opioid Therapy

Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid prescriptions exceeding 50 oral MMEs/day when new, postoperative discharge prescriptions are added to existing opioid therapy (NCT04955444)
Timeframe: Up to 2 days

InterventionParticipants (Count of Participants)
Historical Control Group9
Post-implementation Group0

Other Studies

1 other study available for acetaminophen and Diseases of Endocrine System

ArticleYear
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
    Annals of surgery, 2021, 08-01, Volume: 274, Issue:2

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female

2021
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
    Annals of surgery, 2021, 08-01, Volume: 274, Issue:2

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female

2021
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
    Annals of surgery, 2021, 08-01, Volume: 274, Issue:2

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female

2021
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
    Annals of surgery, 2021, 08-01, Volume: 274, Issue:2

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female

2021