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acetaminophen and Diabetes Mellitus

acetaminophen has been researched along with Diabetes Mellitus in 17 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
" This paper reviews the reported data related to the effects of diabetes and hypertriglyceridemia, common lifestyle-related diseases in a modern society, on acetaminophen (APAP)-induced hepatotoxicity and nephrotoxicity in rats and mice."8.85Diabetes and hypertriglyceridemia modify the mode of acetaminophen-induced hepatotoxicity and nephrotoxicity in rats and mice. ( Doi, K; Ishida, K, 2009)
" This paper reviews the reported data related to the effects of diabetes and hypertriglyceridemia, common lifestyle-related diseases in a modern society, on acetaminophen (APAP)-induced hepatotoxicity and nephrotoxicity in rats and mice."4.85Diabetes and hypertriglyceridemia modify the mode of acetaminophen-induced hepatotoxicity and nephrotoxicity in rats and mice. ( Doi, K; Ishida, K, 2009)
"Aldose reductase catalyzes the NADPH-linked reduction of hexoses to their respective sugar-alcohols, which are involved in the pathogenesis of "sugar-cataracts"."3.68Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies. ( Alvarez, A; Chávez, M; Chávez-Anaya, E; Medina, C; Medina, MD; Mendoza, R; Ramírez, MG; Sáenz, G; Vaca, G; Vargas, M, 1992)
" The entire spectrum of alcoholic liver disease, including alcoholic hepatitis, may be perfectly mimicked by severe obesity, diabetes, and perhexiline maleate toxicity."3.67Problems in the necropsy diagnosis of alcoholic liver disease. ( Pounder, DJ, 1984)
"Pharmacotherapy in pregnancy is often problematic, since both the mother-to-be and her doctor are often concerned about possible risks for the unborn child."2.42[Drug therapy in pregnancy--a practical guide]. ( Kreienberg, R; Paulus, W; Reister, F, 2004)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's2 (11.76)18.2507
2000's5 (29.41)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lv, H1
Zhang, GJ1
Kang, XX1
Yuan, H1
Lv, YW1
Wang, WW1
Randall, R1
Rashid, K1
Sinha, K1
Sil, PC1
Rosenbloom, AL1
Lipworth, L2
Abdel-Kader, K1
Morse, J1
Stewart, TG1
Kabagambe, EK1
Parr, SK1
Birdwell, KA1
Matheny, ME1
Hung, AM1
Blot, WJ2
Ikizler, TA1
Siew, ED1
Montagnana, M1
Caputo, M1
Giavarina, D1
Lippi, G1
Doi, K1
Ishida, K1
Jih, JS1
Chen, YJ1
Lin, MW1
Chen, YC1
Chen, TJ1
Huang, YL1
Chen, CC1
Lee, DD1
Chang, YT1
Wang, WJ1
Liu, HN1
Kon, K1
Ikejima, K1
Okumura, K1
Arai, K1
Aoyama, T1
Watanabe, S1
Friis, S1
Mellemkjaer, L1
Signorello, LB1
Johnsen, SP1
Nielsen, GL1
McLaughlin, JK1
Olsen, JH1
Reister, F1
Paulus, W1
Kreienberg, R1
Bales, JR1
Higham, DP1
Howe, I1
Nicholson, JK1
Sadler, PJ1
Vesterqvist, O1
Gréen, K1
Pounder, DJ1
Antonini Revaz, S1
Morabia, A1
Goehring, C1
Stalder, H1
Vaca, G1
Ramírez, MG1
Vargas, M1
Mendoza, R1
Chávez-Anaya, E1
Medina, MD1
Alvarez, A1
Medina, C1
Sáenz, G1
Chávez, M1
Adithan, C1
Danda, D1
Swaminathan, RP1
Indhiresan, J1
Shashindran, CH1
Bapna, JS1
Chandrasekar, S1
Moses, AM1
Miller, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients[NCT05637216]Phase 240 participants (Anticipated)Interventional2023-08-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for acetaminophen and Diabetes Mellitus

ArticleYear
An update on oxidative stress-mediated organ pathophysiology.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Acetaminophen; Animals; Antioxidants; Arsenic; Cadmium; Carbon Tetrachloride; Cisplatin; Diabetes Me

2013
Overview on self-monitoring of blood glucose.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 402, Issue:1-2

    Topics: Acetaminophen; Blood Glucose Self-Monitoring; Calibration; Diabetes Mellitus; Hematocrit; Humans; Hy

2009
Diabetes and hypertriglyceridemia modify the mode of acetaminophen-induced hepatotoxicity and nephrotoxicity in rats and mice.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Diabetes M

2009
[Drug therapy in pregnancy--a practical guide].
    MMW Fortschritte der Medizin, 2004, Mar-11, Volume: 146, Issue:11

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Bacte

2004
Drug-induced dilutional hyponatremia.
    The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23

    Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate

1974

Other Studies

12 other studies available for acetaminophen and Diabetes Mellitus

ArticleYear
Factors interfering with the accuracy of five blood glucose meters used in Chinese hospitals.
    Journal of clinical laboratory analysis, 2013, Volume: 27, Issue:5

    Topics: Acetaminophen; Ascorbic Acid; Blood Chemical Analysis; Blood Glucose; China; Diabetes Mellitus; Dime

2013
Sudden death of a young woman attributed to diabetic ketoacidosis.
    Journal of forensic and legal medicine, 2013, Volume: 20, Issue:8

    Topics: Acetaminophen; Acetone; Adolescent; Cause of Death; Death, Sudden; Dextromethorphan; Diabetes Mellit

2013
High prevalence of non-steroidal anti-inflammatory drug use among acute kidney injury survivors in the southern community cohort study.
    BMC nephrology, 2016, 11-24, Volume: 17, Issue:1

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroida

2016
Epidemiological features and costs of herpes zoster in Taiwan: a national study 2000 to 2006.
    Acta dermato-venereologica, 2009, Volume: 89, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; An

2009
Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 299, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cell Death; Chemical and Drug Induced Liver Injury

2010
A population-based cohort study of mortality among adults prescribed paracetamol in Denmark.
    Journal of clinical epidemiology, 2003, Volume: 56, Issue:8

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Cardiovascular Diseases; Cause of Death; Cerebrovascu

2003
Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine.
    Clinical chemistry, 1984, Volume: 30, Issue:3

    Topics: Acetaminophen; Adult; Alcohols; Animals; Chemical Phenomena; Chemistry; Diabetes Mellitus; Fasting;

1984
Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions.
    Prostaglandins, 1984, Volume: 27, Issue:4

    Topics: Acetaminophen; Adult; Amino Acid Metabolism, Inborn Errors; Aspirin; Circadian Rhythm; Diabetes Mell

1984
Problems in the necropsy diagnosis of alcoholic liver disease.
    The American journal of forensic medicine and pathology, 1984, Volume: 5, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; D

1984
[Evaluation of drug prescription in the primary care clinic in Geneva in 1997].
    Schweizerische medizinische Wochenschrift, 1999, Dec-11, Volume: 129, Issue:49

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Community He

1999
Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies.
    Archives of medical research, 1992,Spring, Volume: 23, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Animals; Black People

1992
Effect of diabetes mellitus on salivary paracetamol elimination.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabe

1988