acetaminophen has been researched along with Depressive Disorder, Major in 5 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to determine the efficacy of preemptive analgesia with paracetamol and ibuprofen to reduce the intensity and incidence of headache and myalgia after electroconvulsive therapy (ECT)." | 9.30 | Effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia in patients after electroconvulsive therapy: A placebo-controlled, double-blind, randomized clinical trial. ( Akbas, S; Karaaslan, E; Ozkan, AS; Zayman, EP, 2019) |
| "This study intended to determine the prevalence of hypokalemia and its clinical correlates in acute psychiatric illness among hypokalemic and normokalemic patients after acetaminophen overdose." | 7.76 | High prevalence of hypokalemia after acute acetaminophen overdose: impact of psychiatric illness. ( Al-jabi, SW; Awang, R; Syed Sulaiman, SA; Zyoud, SH, 2010) |
| "The aim of this study is to determine the efficacy of preemptive analgesia with paracetamol and ibuprofen to reduce the intensity and incidence of headache and myalgia after electroconvulsive therapy (ECT)." | 5.30 | Effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia in patients after electroconvulsive therapy: A placebo-controlled, double-blind, randomized clinical trial. ( Akbas, S; Karaaslan, E; Ozkan, AS; Zayman, EP, 2019) |
| "This study intended to determine the prevalence of hypokalemia and its clinical correlates in acute psychiatric illness among hypokalemic and normokalemic patients after acetaminophen overdose." | 3.76 | High prevalence of hypokalemia after acute acetaminophen overdose: impact of psychiatric illness. ( Al-jabi, SW; Awang, R; Syed Sulaiman, SA; Zyoud, SH, 2010) |
| "Recently, seizure-induced cyclooxygenase (COX)-mediated postictal vasoconstriction, accompanied by cerebral hypoperfusion and hypoxia, has been identified as a candidate mechanism in experimentally induced seizures in rats." | 3.11 | Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE). ( Hofmeijer, J; Pottkämper, JCM; van Putten, MJAM; van Waarde, JA; van Wingen, GA; Verdijk, JPAJ; Verwijk, E, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verdijk, JPAJ | 1 |
| Pottkämper, JCM | 1 |
| Verwijk, E | 1 |
| van Wingen, GA | 1 |
| van Putten, MJAM | 1 |
| Hofmeijer, J | 1 |
| van Waarde, JA | 1 |
| Karaaslan, E | 1 |
| Akbas, S | 1 |
| Ozkan, AS | 1 |
| Zayman, EP | 1 |
| Kaddurah-Daouk, R | 1 |
| Weinshilboum, RM | 1 |
| Zyoud, SH | 1 |
| Awang, R | 1 |
| Syed Sulaiman, SA | 1 |
| Al-jabi, SW | 1 |
| Vitiello, B | 1 |
| Pearson, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| StudY of Effect of Nimodipine and Acetaminophen on Postictal Symptoms After ECT[NCT04028596] | Phase 2 | 34 participants (Actual) | Interventional | 2019-12-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for acetaminophen and Depressive Disorder, Major
| Article | Year |
|---|---|
Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology.
Topics: Acetaminophen; Animals; Antipsychotic Agents; Chemical and Drug Induced Liver Injury; Depressive Dis | 2014 |
2 trials available for acetaminophen and Depressive Disorder, Major
| Article | Year |
|---|---|
Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE).
Topics: Acetaminophen; Animals; Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalograph | 2022 |
Effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia in patients after electroconvulsive therapy: A placebo-controlled, double-blind, randomized clinical trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Depressive Disorder, Major; Double-Blind Method; Ele | 2019 |
2 other studies available for acetaminophen and Depressive Disorder, Major
| Article | Year |
|---|---|
High prevalence of hypokalemia after acute acetaminophen overdose: impact of psychiatric illness.
Topics: Acetaminophen; Adjustment Disorders; Adolescent; Adult; Anxiety Disorders; Cohort Studies; Depressiv | 2010 |
A depressed adolescent at high risk of suicidal behavior.
Topics: Acetaminophen; Adolescent; Antidepressive Agents; Cognitive Behavioral Therapy; Combined Modality Th | 2008 |