Page last updated: 2024-10-22

acetaminophen and Delayed Effects, Prenatal Exposure

acetaminophen has been researched along with Delayed Effects, Prenatal Exposure in 172 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"The association between acetaminophen use during pregnancy and the development of attention deficit hyperactivity disorder (ADHD) in the offspring may be due to bias."9.05Acetaminophen use during pregnancy and the risk of attention deficit hyperactivity disorder: A causal association or bias? ( Filion, KB; Masarwa, R; Platt, RW, 2020)
"Acetaminophen (paracetamol) is available over the counter in most countries and is widely considered to be safe for use during pregnancy; studies report gestational exposures to acetaminophen that lie in the 46%-65% range."8.93Use of acetaminophen (paracetamol) during pregnancy and the risk of autism spectrum disorder in the offspring. ( Andrade, C, 2016)
"The possible association between acetaminophen use during pregnancy and childhood asthma has been a subject of interest based on the theory that acetaminophen metabolism may deplete glutathione in the developing lung, leading to oxidative damage and inflammation."8.86Childhood asthma and use during pregnancy of acetaminophen. A critical review. ( Ang, R; Breitmeyer, J; Royal, MA; Scialli, AR, 2010)
"Acetaminophen is one of the most commonly used drugs during pregnancy globally."8.12Maternal use of acetaminophen during pregnancy and neurobehavioral problems in offspring at 3 years: A prospective cohort study. ( Kjerulff, KH; Sznajder, KK; Teti, DM, 2022)
"Prior studies have raised concern about maternal acetaminophen use during pregnancy and increased risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in their children; however, most studies have relied on maternal self-report."7.96Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. ( Azuine, RE; Hong, X; Hou, W; Ji, Y; Pearson, C; Riley, A; Wang, G; Wang, X; Zhang, Y; Zuckerman, B, 2020)
"Maternal acetaminophen use during pregnancy is common and has been associated with childhood behavioural problems among offspring, specifically hyperactivity and conduct problems."7.96Maternal acetaminophen use during pregnancy and childhood behavioural problems: Discrepancies between mother- and teacher-reported outcomes. ( Collett, BR; Parker, SE; Werler, MM, 2020)
"Acetaminophen is used by the majority of pregnant women, and some continue to use for many weeks in pregnancy."7.96Acetaminophen use in pregnancy: Examining prevalence, timing, and indication of use in a prospective birth cohort. ( Bandoli, G; Chambers, C; Palmsten, K, 2020)
"Over-the-counter analgesic use during pregnancy, particularly acetaminophen, may be associated with negative developmental outcomes in children."7.96Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood. ( Bassani, DG; Bertoldi, AD; Boing, AC; da Silva Dal Pizzol, T; Domingues, MR; Freitas Silveira, M; Miranda, VIA; Oken, E; Rifas-Shiman, SL; Santos, IS; Silveira, MPT; Tovo-Rodrigues, L, 2020)
"Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination."7.91In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019)
"This study explored the association between exposure to acetaminophen during pregnancy and pubertal development using data from 15,822 boys and girls in the longitudinal Puberty Cohort, nested within the Danish National Birth Cohort."7.91Acetaminophen (Paracetamol) Exposure During Pregnancy and Pubertal Development in Boys and Girls From a Nationwide Puberty Cohort. ( Brix, N; Ernst, A; Lauridsen, LLB; Liew, Z; Olsen, J; Olsen, LH; Parner, ET; Ramlau-Hansen, CH, 2019)
"There was no strong association between prenatal acetaminophen exposure and childhood BMI, but the findings on frequent prenatal exposure to acetaminophen and overweight in girls warrant further investigation."7.91Prenatal Exposure to Acetaminophen and Overweight in Childhood. ( Ernst, A; Li, J; Liew, Z; Morgen, CS; Nohr, EA; Olsen, J; Sørensen, TIA, 2019)
" We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child."7.88Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018)
"Infections in early life have been linked to type 1 diabetes (T1D) risk, but no previous study has comprehensively analysed exposure to antibiotics, acetaminophen and infections during pregnancy and early childhood in relation to offspring risk of T1D."7.88Antibiotics, acetaminophen and infections during prenatal and early life in relation to type 1 diabetes. ( Joner, G; Kahrs, CR; Mårild, K; Njølstad, PR; Skrivarhaug, T; Stene, LC; Størdal, K; Tapia, G, 2018)
"Paracetamol or acetaminophen (APAP) is commonly used as a first line treatment of pain and fever in pregnancy."7.88Paracetamol/Acetaminophen During Pregnancy Induces Prenatal Ductus Arteriosus Closure. ( Allegaert, K; Becquet, O; Bonnet, D; Lapillonne, A; Ville, Y, 2018)
"Some studies have suggested that maternal acetaminophen use during pregnancy is associated with asthma in the offspring, and coffee consumption may modify the toxicity of acetaminophen."7.83Association of prenatal exposure to acetaminophen and coffee with childhood asthma. ( Agerbo, E; Bech, BH; Li, J; Liew, Z; Liu, X; Olsen, J; Pedersen, LH; Yuan, W, 2016)
"Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy."7.83Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study. ( Liew, Z; Olsen, J; Ritz, B; Virk, J, 2016)
"Acetaminophen is extensively used during pregnancy."7.83Acetaminophen use in pregnancy and neurodevelopment: attention function and autism spectrum symptoms. ( Andiarena, A; Avella-Garcia, CB; Fortuny, J; Galán, IR; García-Esteban, R; Iñiguez, C; Julvez, J; Rebordosa, C; Rodríguez-Bernal, CL; Santa-Marina, L; Sunyer, J; Tardón, A, 2016)
"Acetaminophen use was assessed by questionnaire completion at 18 and 32 weeks of pregnancy and when the child was 61 months old."7.83Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding. ( Davey Smith, G; Stergiakouli, E; Thapar, A, 2016)
"Unadjusted models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ratio [OR], 1."7.81Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. ( Bunyavanich, S; Camargo, CA; Gillman, MW; Gold, DR; Litonjua, AA; Rifas-Shiman, SL; Scirica, CV; Sordillo, JE; Weiss, ST, 2015)
"During pregnancy, acetaminophen is one of the very few medications recommended by physicians to treat fever or pain."7.81Prenatal acetaminophen induces liver toxicity in dams, reduces fetal liver stem cells, and increases airway inflammation in adult offspring. ( Arck, P; Barikbin, R; Erhardt, A; Huebener, P; Karimi, K; Keßler, T; Ramisch, K; Thiele, K; Tiegs, G, 2015)
"Acetaminophen (paracetamol) is the most commonly used medication for pain and fever during pregnancy in many countries."7.80Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. ( Lee, PC; Liew, Z; Olsen, J; Rebordosa, C; Ritz, B, 2014)
"Our aim was to replicate and extend the recently found association between acetaminophen use during pregnancy and ADHD symptoms in school-age children."7.80Associations between acetaminophen use during pregnancy and ADHD symptoms measured at ages 7 and 11 years. ( Mitchell, EA; Murphy, R; Thompson, JM; Waldie, KE; Wall, CR, 2014)
"Prenatal and infant acetaminophen exposure has been associated with an increased risk of childhood asthma phenotypes."7.76Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma. ( Henderson, AJ; Holloway, JW; Newson, RB; Ring, SM; Rose-Zerilli, MJ; Shaheen, SO, 2010)
"To estimate whether prenatal exposure to acetaminophen is associated with risk of diagnosed asthma and asthma symptoms in children."7.75Prenatal exposure to acetaminophen and asthma in children. ( Bracken, MB; Illuzzi, JL; Kang, EM; Lundsberg, LS, 2009)
" Each article has poor power to show risks of acetaminophen, however, the integration of the articles that showed adverse effects of acetaminophen may have power to show them."6.55Is acetaminophen safe in pregnancy? ( Toda, K, 2017)
" We conclude that future studies are urgently needed to reconsider the safety and dosage of APAP during pregnancy and - based on the advances made in the field of reproduction as well as APAP metabolism - we propose pathways, which should be addressed in future research and clinical endeavors."6.49Acetaminophen and pregnancy: short- and long-term consequences for mother and child. ( Arck, P; Erhardt, A; Kessler, T; Thiele, K; Tiegs, G, 2013)
"Acetaminophen is a widely used medication for the treatment of pain and fever in children and pregnant women."6.49Acetaminophen and asthma. ( Henderson, AJ; Shaheen, SO, 2013)
"Two toxins most implicated in the U."5.48Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). ( Good, P, 2018)
"(1) Gastroschisis is a severe defect in the closure of the abdominal wall in newborns."5.32Gastroschisis and pseudoephedrine during pregnancy. ( , 2004)
"Paracetamol (acetaminophen) use during pregnancy and early childhood was accepted as safe in the 1970s, but is now a subject of considerable concern."5.22The safety of pediatric use of paracetamol (acetaminophen): a narrative review of direct and indirect evidence. ( Anderson, LG; Bono-Lunn, D; Cendejas Hernandez, J; Jones Iii, JP; Konsoula, Z; Kuchibhatla, M; Lawton, VG; Palkar, A; Parker, W; Patel, E; Reissner, KJ; Sarafian, JT, 2022)
"An increasing number of cohort studies have suggested that maternal use of acetaminophen during pregnancy was associated with increased risk for asthma; neurodevelopmental disorders, especially ADHD and behavioral problems; and genital malformations in the offspring."5.12Intrauterine Exposure to Acetaminophen and Adverse Developmental Outcomes: Epidemiological Findings and Methodological Issues. ( Ernst, A; Liew, Z, 2021)
"The association between acetaminophen use during pregnancy and the development of attention deficit hyperactivity disorder (ADHD) in the offspring may be due to bias."5.05Acetaminophen use during pregnancy and the risk of attention deficit hyperactivity disorder: A causal association or bias? ( Filion, KB; Masarwa, R; Platt, RW, 2020)
" Evidence of association was convincing (class I) for maternal pre-pregnancy obesity (OR 1·63, 95% CI 1·49 to 1·77), childhood eczema (1·31, 1·20 to 1·44), hypertensive disorders during pregnancy (1·29, 1·22 to 1·36), pre-eclampsia (1·28, 1·21 to 1·35), and maternal acetaminophen exposure during pregnancy (RR 1·25, 95% CI 1·17 to 1·34)."5.05Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review. ( Brunoni, AR; Carvalho, AF; Dragioti, E; Fornaro, M; Fusar-Poli, P; Grabovac, I; Hong, SH; Jacob, L; Jeong, GH; Kim, JH; Kim, JY; Koyanagi, A; Kronbichler, A; Lee, E; Lee, J; Lee, KH; Lee, S; Oh, H; Radua, J; Rais, TB; Salazar de Pablo, G; Schuch, F; Shin, JI; Smith, L; Solmi, M; Stickley, A; Stubbs, B; Thompson, T; Yang, L, 2020)
"Acetaminophen is a widely used medication for fever and pain management during pregnancy."5.01Association of maternal prenatal acetaminophen use with the risk of attention deficit/hyperactivity disorder in offspring: A meta-analysis. ( Gou, X; Mu, D; Qu, Y; Shi, J; Tang, J; Tang, Y; Wang, Y; Xiao, D, 2019)
"The non-prescription medication paracetamol (acetaminophen, APAP) is currently recommended as a safe pain and fever treatment during pregnancy."4.98Prenatal paracetamol exposure and child neurodevelopment: A review. ( Bauer, AZ; Bornehag, CG; Herbert, MR; Kriebel, D; Swan, SH, 2018)
"Acetaminophen is the analgesic and antipyretic most commonly used during pregnancy."4.98Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Cohort Studies. ( Gorelik, E; Levine, H; Masarwa, R; Matok, I; Perlman, A; Reif, S, 2018)
"Paracetamol (acetaminophen) is the most commonly used drug in the world, with a long record of use in acute and chronic pain."4.98Long-term adverse effects of paracetamol - a review. ( Dear, JW; MacIntyre, IM; McCrae, JC; Morrison, EE; Webb, DJ, 2018)
"A number of studies indicate that acetaminophen taken during pregnancy may have a programming effect on the fetal brain development."4.95Fetal programming of mental health by acetaminophen? Response to the SMFM statement: prenatal acetaminophen use and ADHD. ( Liew, Z; Olsen, J, 2017)
" To perform the search for the most suitable and representative articles, keywords were selected ("asthma," "paracetamol" and "acetaminophen")."4.95The association between paracetamol and asthma is still under debate. ( Gonzalez-Barcala, FJ; Lourido-Cebreiro, T; Salgado, FJ; Valdes, L, 2017)
"Acetaminophen (paracetamol) is available over the counter in most countries and is widely considered to be safe for use during pregnancy; studies report gestational exposures to acetaminophen that lie in the 46%-65% range."4.93Use of acetaminophen (paracetamol) during pregnancy and the risk of autism spectrum disorder in the offspring. ( Andrade, C, 2016)
"Paracetamol (acetaminophen) remains the first line for the treatment of pain and fever in pregnancy."4.91Use of paracetamol during pregnancy and child neurological development. ( Dan, B; de Fays, L; De Smet, K; Dogné, JM; Hamdani, J; Sawchik, J; Van Malderen, K; Verlinden, V, 2015)
"Studies comparing self-reported maternal acetaminophen use during pregnancy to development of ADHD or ADHD-like behaviors in offspring between the ages of 3 and 12 years."4.91Association Between Prenatal Acetaminophen Exposure and Future Risk of Attention Deficit/Hyperactivity Disorder in Children. ( Erramouspe, J; Hayes, VA; Hoover, RM, 2015)
"Although the use of acetaminophen is weakly associated with asthma/wheezing, the widespread use of the drug might have important public health implications."4.87Early exposure to acetaminophen and allergic disorders. ( Garcia-Marcos, L; Perez-Fernandez, V; Sanchez-Solis, M, 2011)
"The possible association between acetaminophen use during pregnancy and childhood asthma has been a subject of interest based on the theory that acetaminophen metabolism may deplete glutathione in the developing lung, leading to oxidative damage and inflammation."4.86Childhood asthma and use during pregnancy of acetaminophen. A critical review. ( Ang, R; Breitmeyer, J; Royal, MA; Scialli, AR, 2010)
"We did not observe any association between maternal acetaminophen intake any time before or during pregnancy and low cognition composite score of offspring."4.31Maternal acetaminophen use and cognitive development at 4 years: the Ontario Birth Study. ( Adel Khani, N; Arneja, J; Brooks, JD; Hung, RJ; Knight, JA; Levitan, RD; Lye, JM; Lye, SJ; Matthews, SG; Seeto, RA; Wong, J, 2023)
"Epidemiological investigation suggested that the use of acetaminophen during pregnancy may cause offspring testicular dysplasia, but no systematic study has been conducted."4.31Prenatal exposure to acetaminophen at different doses, courses and time causes testicular dysplasia in offspring mice and its mechanism. ( Chen, S; Guo, Y; Kong, Z; Liu, Y; Wang, H, 2023)
"Acetaminophen is one of the most commonly used drugs during pregnancy globally."4.12Maternal use of acetaminophen during pregnancy and neurobehavioral problems in offspring at 3 years: A prospective cohort study. ( Kjerulff, KH; Sznajder, KK; Teti, DM, 2022)
"Acetaminophen (APAP) is available over-the-counter and widely regarded as safe for use in pregnancy."4.02Maternal paracetamol intake and fetal ductus arteriosus constriction/closure: comprehensive signal evaluation using the Austin Bradford Hill criteria. ( Bai, S; Hauben, M; Hung, E; Lobello, K; Tressler, C; Zucal, VP, 2021)
"The majority of epidemiological studies concerning possible adverse effects of paracetamol (acetaminophen) in pregnancy have been focussed on childhood asthma."3.96Associations between paracetamol (acetaminophen) intake between 18 and 32 weeks gestation and neurocognitive outcomes in the child: A longitudinal cohort study. ( Clark, R; Ellis, G; Golding, J; Gregory, S; Iles-Caven, Y; Northstone, K, 2020)
" 2018;187(8):1817-1827) conducted a meta-analysis of the association between in utero acetaminophen exposure and risks of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD)."3.96Invited Commentary: The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology. ( Gilman, SE; Hornig, M, 2020)
"Examine associations of acetaminophen and ibuprofen use during pregnancy and infancy with executive function and behaviour problems in children."3.96Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour. ( Bertoldi, AD; Cardenas, A; Hivert, MF; Oken, E; Rifas-Shiman, SL; Tiemeier, H, 2020)
"Prior studies have raised concern about maternal acetaminophen use during pregnancy and increased risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in their children; however, most studies have relied on maternal self-report."3.96Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. ( Azuine, RE; Hong, X; Hou, W; Ji, Y; Pearson, C; Riley, A; Wang, G; Wang, X; Zhang, Y; Zuckerman, B, 2020)
"Maternal acetaminophen use during pregnancy is common and has been associated with childhood behavioural problems among offspring, specifically hyperactivity and conduct problems."3.96Maternal acetaminophen use during pregnancy and childhood behavioural problems: Discrepancies between mother- and teacher-reported outcomes. ( Collett, BR; Parker, SE; Werler, MM, 2020)
"Acetaminophen is used by the majority of pregnant women, and some continue to use for many weeks in pregnancy."3.96Acetaminophen use in pregnancy: Examining prevalence, timing, and indication of use in a prospective birth cohort. ( Bandoli, G; Chambers, C; Palmsten, K, 2020)
"Over-the-counter analgesic use during pregnancy, particularly acetaminophen, may be associated with negative developmental outcomes in children."3.96Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood. ( Bassani, DG; Bertoldi, AD; Boing, AC; da Silva Dal Pizzol, T; Domingues, MR; Freitas Silveira, M; Miranda, VIA; Oken, E; Rifas-Shiman, SL; Santos, IS; Silveira, MPT; Tovo-Rodrigues, L, 2020)
" Acetaminophen use during pregnancy was retrospectively assessed at the perinatal follow-up."3.96Low neurodevelopmental performance and behavioural/emotional problems at 24 and 48 months in Brazilian children exposed to acetaminophen during foetal development. ( Anselmi, L; Barros, AJD; Barros, FC; Bertoldi, AD; Carpena, MX; Martins-Silva, T; Matijasevich, A; Santos, IS; Tovo-Rodrigues, L, 2020)
" Thus, in the present study we assessed the sexual partner preference (SPP) of adult male rats prenatally treated with acetaminophen (APAP), an analgesic/antipyretic drug that inhibits COX-2 and is commonly used and prescribed during pregnancy."3.96Nature and nurture of sexual partner preference: Teachings from prenatal administration of acetaminophen in male rats. ( Barradas-Moctezuma, M; Coria-Avila, GA; Díaz-Estrada, VX; Herrera-Covarrubias, D; Manzo, J, 2020)
"Despite evidence of an association between prenatal acetaminophen exposure and attention-deficit/hyperactivity disorder (ADHD) in offspring, the drug is not contraindicated during pregnancy, possibly because prior studies have relied on maternal self-report, failed to quantify acetaminophen dose, and lacked mechanistic insight."3.96Association of Prenatal Acetaminophen Exposure Measured in Meconium With Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity. ( Aw, N; Baccarelli, AA; Baker, BH; Bellenger, JP; Boivin, A; Gillet, V; Laue, HE; Lepage, JF; Lugo-Candelas, C; Posner, J; Rahman, T; Takser, L; Whittingstall, K; Wu, H, 2020)
"Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination."3.91In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019)
" Maternal use of acetaminophen was assessed in the first trimester, second trimester, and third trimester of pregnancy and over the period from 3 months before pregnancy to the date of last menstrual cycle."3.91Prenatal Exposure to Acetaminophen and the Risk of Attention-Deficit/Hyperactivity Disorder: A Nationwide Study in Taiwan. ( Bai, YM; Chen, MH; Chen, TJ; Hsu, JW; Huang, KL; Li, CT; Lin, WC; Pan, TL; Su, TP; Tsai, SJ; Wang, PW, 2019)
"Acetaminophen is the only over-the-counter pain reliever that is not contraindicated during pregnancy, but recent studies have questioned whether acetaminophen is safe for the fetus, particularly the developing brain."3.91Association Between Meconium Acetaminophen and Childhood Neurocognitive Development in GESTE, a Canadian Cohort Study. ( Abdelouahab, N; Baccarelli, AA; Bellenger, JP; Brennan, KJM; Burris, HH; Cassoulet, R; Coull, BA; Desautels, AS; Laue, HE; Serme-Gbedo, YK; Takser, L; Weisskopf, MG, 2019)
"This study explored the association between exposure to acetaminophen during pregnancy and pubertal development using data from 15,822 boys and girls in the longitudinal Puberty Cohort, nested within the Danish National Birth Cohort."3.91Acetaminophen (Paracetamol) Exposure During Pregnancy and Pubertal Development in Boys and Girls From a Nationwide Puberty Cohort. ( Brix, N; Ernst, A; Lauridsen, LLB; Liew, Z; Olsen, J; Olsen, LH; Parner, ET; Ramlau-Hansen, CH, 2019)
"Frequent maternal use of acetaminophen in pregnancy has been linked to attention-deficit/hyperactivity disorder (ADHD) in children, but concerns regarding uncontrolled confounding remain."3.91Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses' Health Study II. ( Ascherio, A; Kioumourtzoglou, MA; Liew, Z; O'Reilly, ÉJ; Roberts, AL; Weisskopf, MG, 2019)
"There was no strong association between prenatal acetaminophen exposure and childhood BMI, but the findings on frequent prenatal exposure to acetaminophen and overweight in girls warrant further investigation."3.91Prenatal Exposure to Acetaminophen and Overweight in Childhood. ( Ernst, A; Li, J; Liew, Z; Morgen, CS; Nohr, EA; Olsen, J; Sørensen, TIA, 2019)
" We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child."3.88Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018)
"Paracetamol (acetaminophen or N-acetyl-p-aminophenol) is considered a safe analgesic and antipyretic nonsteroidal antiinflammatory drug commonly used during pediatric ages and during pregnancy."3.88A Case of Cardiomyopathy Due to Premature Ductus Arteriosus Closure: The Flip Side of Paracetamol. ( Corsello, G; Giuffrè, M; La Placa, S; Piro, E; Schierz, IAM, 2018)
"Infections in early life have been linked to type 1 diabetes (T1D) risk, but no previous study has comprehensively analysed exposure to antibiotics, acetaminophen and infections during pregnancy and early childhood in relation to offspring risk of T1D."3.88Antibiotics, acetaminophen and infections during prenatal and early life in relation to type 1 diabetes. ( Joner, G; Kahrs, CR; Mårild, K; Njølstad, PR; Skrivarhaug, T; Stene, LC; Størdal, K; Tapia, G, 2018)
"Paracetamol or acetaminophen (APAP) is commonly used as a first line treatment of pain and fever in pregnancy."3.88Paracetamol/Acetaminophen During Pregnancy Induces Prenatal Ductus Arteriosus Closure. ( Allegaert, K; Becquet, O; Bonnet, D; Lapillonne, A; Ville, Y, 2018)
"Paracetamol/acetaminophen (N-Acetyl-p-Aminophenol; APAP) is the preferred analgesic for pain relief and fever during pregnancy."3.85Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour. ( Andrade, AM; Bak Holm, J; Bornehag, CG; Brunak, S; Finkielman, OTE; Hay-Schmidt, A; Høgsbro, CF; Jegou, B; Jensen, BAH; Jensen, TK; Johansen, KH; Kristensen, DM; Kristiansen, K; Swan, SH, 2017)
"To estimate the association between maternal use of acetaminophen during pregnancy and of paternal use before pregnancy with attention-deficit/hyperactivity disorder (ADHD) in offspring while adjusting for familial risk for ADHD and indications of acetaminophen use."3.85Prenatal Exposure to Acetaminophen and Risk of ADHD. ( Brandlistuen, RE; Davey Smith, G; Gustavson, K; Håberg, SE; Hornig, M; Knudsen, GP; Lipkin, WI; Magnus, P; Nordeng, H; Reichborn-Kjennerud, T; Stoltenberg, C; Surén, P; Susser, E; Ystrom, E, 2017)
"Some studies have suggested that maternal acetaminophen use during pregnancy is associated with asthma in the offspring, and coffee consumption may modify the toxicity of acetaminophen."3.83Association of prenatal exposure to acetaminophen and coffee with childhood asthma. ( Agerbo, E; Bech, BH; Li, J; Liew, Z; Liu, X; Olsen, J; Pedersen, LH; Yuan, W, 2016)
"Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy."3.83Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study. ( Liew, Z; Olsen, J; Ritz, B; Virk, J, 2016)
"Acetaminophen is extensively used during pregnancy."3.83Acetaminophen use in pregnancy and neurodevelopment: attention function and autism spectrum symptoms. ( Andiarena, A; Avella-Garcia, CB; Fortuny, J; Galán, IR; García-Esteban, R; Iñiguez, C; Julvez, J; Rebordosa, C; Rodríguez-Bernal, CL; Santa-Marina, L; Sunyer, J; Tardón, A, 2016)
"Acetaminophen (paracetamol) is the most commonly used pain and fever medication during pregnancy, and recently has been linked to hyperactivity and behavioral problems in children."3.83Prenatal Use of Acetaminophen and Child IQ: A Danish Cohort Study. ( Arah, OA; Liew, Z; Olsen, J; Ritz, B; Virk, J, 2016)
"Acetaminophen use was assessed by questionnaire completion at 18 and 32 weeks of pregnancy and when the child was 61 months old."3.83Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding. ( Davey Smith, G; Stergiakouli, E; Thapar, A, 2016)
"Unadjusted models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ratio [OR], 1."3.81Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. ( Bunyavanich, S; Camargo, CA; Gillman, MW; Gold, DR; Litonjua, AA; Rifas-Shiman, SL; Scirica, CV; Sordillo, JE; Weiss, ST, 2015)
"During pregnancy, acetaminophen is one of the very few medications recommended by physicians to treat fever or pain."3.81Prenatal acetaminophen induces liver toxicity in dams, reduces fetal liver stem cells, and increases airway inflammation in adult offspring. ( Arck, P; Barikbin, R; Erhardt, A; Huebener, P; Karimi, K; Keßler, T; Ramisch, K; Thiele, K; Tiegs, G, 2015)
"Acetaminophen (paracetamol) is the most commonly used medication for pain and fever during pregnancy in many countries."3.80Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders. ( Lee, PC; Liew, Z; Olsen, J; Rebordosa, C; Ritz, B, 2014)
"Our aim was to replicate and extend the recently found association between acetaminophen use during pregnancy and ADHD symptoms in school-age children."3.80Associations between acetaminophen use during pregnancy and ADHD symptoms measured at ages 7 and 11 years. ( Mitchell, EA; Murphy, R; Thompson, JM; Waldie, KE; Wall, CR, 2014)
"Increasing frequency of aspirin use during pregnancy was associated with an increased risk of psychotic experiences (adjusted OR 1."3.77Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence. ( Gunawardana, L; Gunnell, D; Harrison, G; Hollis, C; Lewis, G; Wolke, D; Zammit, S, 2011)
"Acetaminophen has been associated with asthma and is in part metabolised via the glutathione pathway."3.76Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort. ( Ali, D; Barr, RG; Chew, GL; Garfinkel, RS; Goldstein, IF; Miller, RL; Perera, FP; Perzanowski, MS; Tang, D, 2010)
"Prenatal and infant acetaminophen exposure has been associated with an increased risk of childhood asthma phenotypes."3.76Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma. ( Henderson, AJ; Holloway, JW; Newson, RB; Ring, SM; Rose-Zerilli, MJ; Shaheen, SO, 2010)
"To estimate whether prenatal exposure to acetaminophen is associated with risk of diagnosed asthma and asthma symptoms in children."3.75Prenatal exposure to acetaminophen and asthma in children. ( Bracken, MB; Illuzzi, JL; Kang, EM; Lundsberg, LS, 2009)
"Use of acetaminophen in middle to late but not early pregnancy was significantly related to wheezing (odd ratio, 1."3.74Prenatal exposure to acetaminophen and respiratory symptoms in the first year of life. ( Busso, A; Chavez, N; Enriquez, R; Gutierrez, S; Hernandez, E; Pelzel, D; Persky, V; Piorkowski, J; Vergara, C; Wagner-Cassanova, C, 2008)
"We recently found that paracetamol (acetaminophen) use in late pregnancy was associated with an increased risk of early wheezing in the offspring."3.73Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood. ( Headley, JE; Henderson, AJ; Jones, RW; Newson, RB; Shaheen, SO; Strachan, DP; Stratton, FD, 2005)
"We report a case of neonatal transient renal failure after maternal ingestion of diclofenac, paracetamol, and nimesulide during pregnancy."3.72In utero exposure to nonsteroidal anti-inflammatory drugs: neonatal renal failure. ( Benini, D; Cuzzolin, L; Fanos, V; Tatò, L, 2004)
" After culture, embryo morphological and developmental parameters were documented using standardized scoring systems at each dosage concentration."2.82Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system. ( Leung, BW; Leung, TY; Moungmaithong, S; Poon, LC; Sahota, DS; Wang, CC, 2022)
" N-Acetylcysteine should be given according to specific regimens through weight-based dosing tables."2.72Paracetamol overdose in the newborn and infant: a life-threatening event. ( Antonucci, R; Capobianco, G; Cuzzolin, L; Locci, C, 2021)
"The rate of pregnant women with an opioid use disorder has risen drastically in the past 20 years, paralleling that in the general population."2.66Opioid Use and Misuse in Pregnancy. ( Landau, R; Shatil, B, 2020)
" Each article has poor power to show risks of acetaminophen, however, the integration of the articles that showed adverse effects of acetaminophen may have power to show them."2.55Is acetaminophen safe in pregnancy? ( Toda, K, 2017)
"For a woman with chronic pain, adequate use of pain killers during pregnancy is needed."2.53Ongoing Pharmacological Management of Chronic Pain in Pregnancy. ( Källén, B; Reis, M, 2016)
" We conclude that future studies are urgently needed to reconsider the safety and dosage of APAP during pregnancy and - based on the advances made in the field of reproduction as well as APAP metabolism - we propose pathways, which should be addressed in future research and clinical endeavors."2.49Acetaminophen and pregnancy: short- and long-term consequences for mother and child. ( Arck, P; Erhardt, A; Kessler, T; Thiele, K; Tiegs, G, 2013)
"Acetaminophen is a widely used medication for the treatment of pain and fever in children and pregnant women."2.49Acetaminophen and asthma. ( Henderson, AJ; Shaheen, SO, 2013)
"NSAID use in pregnancy is associated with SGA but not preterm birth."1.91Associations of prenatal exposure to non-steroidal anti-inflammatory drugs with preterm birth and small for gestational age infants among women with autoimmune disorders. ( Bandoli, G; Chambers, C; Delker, E; Johnson, D; Kelly, A, 2023)
" Several studies report that long-term exposure to paracetamol in utero is associated with adverse neurodevelopmental outcomes in children, indicating a dose-response effect."1.91Paracetamol use in pregnancy: Not as safe as we may think? ( Krogsrud, SK; Nilsen, K; Staff, AC, 2023)
" An apparent dose-response pattern was observed with an 8% increased risk when the exposure was ≥5 courses prenatally (aHR 1."1.91Prenatal and early-life antibiotic exposure and the risk of atopic dermatitis in children: A nationwide population-based cohort study. ( Chang, YC; Liao, PL; Wei, JC; Wu, HJ; Wu, MC, 2023)
"Acetaminophen is a common analgesic and fever reduction medicine for pregnant women."1.91Course-, dose-, and stage-dependent toxic effects of prenatal acetaminophen exposure on fetal long bone development. ( Chen, L; Gu, H; Guo, Y; Li, B; Li, X; Ma, C; Wang, H; Wen, Y; Xiao, H, 2023)
"Acetaminophen (APAP) has been associated with the development of atopic diseases."1.62Prenatal exposure to acetaminophen increases the risk of atopic dermatitis in children: A nationwide nested case-control study in Taiwan. ( Bai, YM; Chang, YT; Chen, MH; Chen, TJ; Dai, YX; Li, CY; Tsai, SJ, 2021)
"Language delay was more prevalent in boys (12."1.48Prenatal exposure to acetaminophen and children's language development at 30 months. ( Bornehag, CG; Hallerback, MU; Jonsson, BA; Koch, HM; Reichenberg, A; Swan, SH; Wikstrom, S, 2018)
"Two toxins most implicated in the U."1.48Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). ( Good, P, 2018)
"Acetaminophen was used by 27."1.48Is intrauterine exposure to acetaminophen associated with emotional and hyperactivity problems during childhood? Findings from the 2004 Pelotas birth cohort. ( Barros, AJD; Bertoldi, AD; Del-Ponte, B; Entiauspe, L; Loret de Mola, C; Martins-Silva, T; Matijasevich, A; Munhoz, TN; Rohde, LA; Santos, IS; Schneider, BC; Schuler-Faccini, L; Silveira, MF; Tovo-Rodrigues, L; Vianna, FSL, 2018)
"Infections in pregnancy are common, may affect fetal development, and have been linked to offspring autoimmunity."1.46Maternal Infections, Antibiotics, and Paracetamol in Pregnancy and Offspring Celiac Disease: A Cohort Study. ( Kahrs, CR; Mårild, K; Stene, LC; Størdal, K; Tapia, G, 2017)
" In 19-month-old male offspring, epididymal sperm counts were lower than controls, and in ventral prostate an overrepresentation of findings related to hyperplasia was observed in exposed groups compared with controls, particularly in the group dosed with anti-androgens."1.40Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters. ( Axelstad, M; Boberg, J; Christiansen, S; Hass, U; Isling, LK; Jacobsen, PR; Kortenkamp, A; Mandrup, KR; Taxvig, C; Vinggaard, AM, 2014)
"(1) Gastroschisis is a severe defect in the closure of the abdominal wall in newborns."1.32Gastroschisis and pseudoephedrine during pregnancy. ( , 2004)

Research

Studies (172)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.58)18.7374
1990's3 (1.74)18.2507
2000's10 (5.81)29.6817
2010's108 (62.79)24.3611
2020's50 (29.07)2.80

Authors

AuthorsStudies
Novi, DRBS1
Vidigal, CB1
Moura, KF1
da Silva, DG1
Serafim, AFL1
Klein, RM3
Moreira, EG5
Gerardin, DCC3
Ceravolo, GS3
Liew, Z16
Yuan, Y2
Meng, Q2
von Ehrenstein, OS1
Cui, X1
Flores, MES1
Ritz, B7
Bührer, C1
Endesfelder, S1
Scheuer, T1
Schmitz, T1
Moungmaithong, S1
Leung, BW1
Sahota, DS1
Wang, CC1
Leung, TY1
Poon, LC1
Alwan, S1
Conover, EA1
Harris-Sagaribay, L1
Lamm, SH1
Lavigne, SV1
Lusskin, SI2
Obican, SG1
Romeo, AN1
Scialli, AR3
Wisner, KL1
Bauer, AZ3
Swan, SH5
Kriebel, D3
Taylor, HS1
Bornehag, CG5
M Andrade, A1
Olsen, J14
Jensen, RH1
Mitchell, RT2
Skakkebaek, NE2
Kristensen, DM6
O'Sullivan, J1
Cairns, AE1
Plesca, E1
Black, RS1
Frise, C1
Vatish, M1
Cerdeira, AS1
Olstad, EW1
Nordeng, HME1
Sandve, GK1
Lyle, R2
Gervin, K2
Lye, JM1
Knight, JA1
Arneja, J1
Seeto, RA1
Wong, J1
Adel Khani, N1
Brooks, JD1
Levitan, RD1
Matthews, SG1
Lye, SJ1
Hung, RJ1
Patel, E1
Jones Iii, JP1
Bono-Lunn, D1
Kuchibhatla, M1
Palkar, A1
Cendejas Hernandez, J1
Sarafian, JT1
Lawton, VG1
Anderson, LG1
Konsoula, Z1
Reissner, KJ1
Parker, W1
Sznajder, KK1
Teti, DM1
Kjerulff, KH1
Delker, E1
Kelly, A1
Chambers, C2
Johnson, D1
Bandoli, G2
Nilsen, K1
Staff, AC1
Krogsrud, SK1
Ricci, C1
Pablo, LA1
Brown, HK1
Damkier, P5
Chang, YC1
Wu, MC1
Wu, HJ1
Liao, PL1
Wei, JC1
Zehra, A1
Altaf, H1
Ma, C1
Li, X1
Xiao, H1
Li, B1
Gu, H1
Guo, Y2
Wang, H2
Wen, Y1
Chen, L1
Liu, Y2
Chen, S1
Kong, Z1
Rossitto, M2
Ollivier, M1
Déjardin, S1
Pruvost, A2
Brun, C1
Marchive, C2
Nguyen, AL1
Ghettas, A2
Keime, C1
de Massy, B1
Poulat, F2
Philibert, P2
Boizet-Bonhoure, B2
Trønnes, JN1
Wood, M1
Lupattelli, A1
Ystrom, E7
Nordeng, H7
Chen, MH2
Pan, TL1
Wang, PW1
Hsu, JW1
Huang, KL1
Su, TP1
Li, CT1
Lin, WC1
Tsai, SJ2
Chen, TJ2
Bai, YM2
Golding, J1
Gregory, S1
Clark, R1
Ellis, G1
Iles-Caven, Y1
Northstone, K1
Masarwa, R4
Perlman, A3
Levine, H3
Matok, I3
Gilman, SE1
Hornig, M3
Rifas-Shiman, SL3
Cardenas, A1
Hivert, MF1
Tiemeier, H2
Bertoldi, AD4
Oken, E2
Ji, Y1
Azuine, RE1
Zhang, Y1
Hou, W1
Hong, X1
Wang, G1
Riley, A1
Pearson, C1
Zuckerman, B1
Wang, X1
Parker, SE2
Collett, BR1
Werler, MM2
Palmsten, K1
Platt, RW1
Filion, KB1
Pereira, MRF2
Aleixo, JF2
Cavalcanti, LF1
Costa, NO1
Vieira, ML2
Boing, AC1
da Silva Dal Pizzol, T1
Miranda, VIA1
Silveira, MPT1
Freitas Silveira, M1
Domingues, MR1
Santos, IS3
Bassani, DG1
Tovo-Rodrigues, L3
Talge, NM1
Wood, ME2
Carpena, MX1
Martins-Silva, T2
Anselmi, L1
Barros, AJD2
Barros, FC1
Matijasevich, A2
Díaz-Estrada, VX1
Barradas-Moctezuma, M1
Herrera-Covarrubias, D1
Manzo, J1
Coria-Avila, GA1
Baker, BH1
Lugo-Candelas, C1
Wu, H1
Laue, HE2
Boivin, A1
Gillet, V1
Aw, N1
Rahman, T1
Lepage, JF1
Whittingstall, K1
Bellenger, JP2
Posner, J1
Takser, L2
Baccarelli, AA2
Kim, JH1
Kim, JY1
Lee, J1
Jeong, GH1
Lee, E1
Lee, S1
Lee, KH1
Kronbichler, A1
Stubbs, B1
Solmi, M1
Koyanagi, A1
Hong, SH1
Dragioti, E1
Jacob, L1
Brunoni, AR1
Carvalho, AF1
Radua, J1
Thompson, T1
Smith, L1
Oh, H1
Yang, L1
Grabovac, I1
Schuch, F1
Fornaro, M1
Stickley, A1
Rais, TB1
Salazar de Pablo, G1
Shin, JI1
Fusar-Poli, P1
Shatil, B1
Landau, R1
Inoue, K2
Ernst, A4
Tseng, WL1
Ramlau-Hansen, CH2
Strandberg-Larsen, K3
Arah, OA2
Obel, C1
Li, J3
Montagnini, BG1
Pereira, MJD1
Forcato, S1
Kiss, ACI1
de Mello Miyasaki, AM1
Rigobello, C2
Crespigio, J1
Flaiban, KK1
Bracarense, AP1
Mazzucatto, BC1
Barbosa, DS2
Locci, C1
Cuzzolin, L2
Capobianco, G1
Antonucci, R1
Hauben, M1
Bai, S1
Hung, E1
Lobello, K1
Tressler, C1
Zucal, VP1
Li, CY1
Dai, YX1
Chang, YT1
Debiasi, JD1
Ursini, LG1
Michelin, AP1
Matsumoto, AK1
Alemany, S1
Avella-García, C1
García-Esteban, R2
Cadman, T1
López-Vicente, M1
González, L1
Riaño Galán, I1
Andiarena, A2
Casas, M1
Margetaki, K1
Lawlor, DA1
El Marroun, H1
Iñiguez, C2
Tardón, A2
Santa-Marina, L2
Júlvez, J2
Porta, D1
Chatzi, L1
Sunyer, J2
Allegaert, K2
Ceulemans, M1
van den Anker, J1
Hay-Schmidt, A1
Finkielman, OTE1
Jensen, BAH1
Høgsbro, CF1
Bak Holm, J1
Johansen, KH1
Jensen, TK3
Andrade, AM1
Brunak, S2
Jegou, B4
Kristiansen, K2
Kilcoyne, KR1
Taney, J1
Anastasio, H1
Paternostro, A1
Berghella, V1
Roman, A1
Reichborn-Kjennerud, T3
Toda, K1
Gustavson, K2
Brandlistuen, RE5
Knudsen, GP2
Magnus, P2
Susser, E1
Davey Smith, G4
Stoltenberg, C2
Surén, P2
Håberg, SE3
Lipkin, WI2
Wolraich, ML1
Petersen, TG1
Andersen, AN1
Andersen, GL1
Andersen, PK1
Martinussen, T1
Rebordosa, C5
Tollånes, MC1
Uldall, P1
Wilcox, AJ1
Reichenberg, A2
Hallerback, MU2
Wikstrom, S2
Koch, HM4
Jonsson, BA1
Herbert, MR1
Schierz, IAM1
Giuffrè, M1
Piro, E1
La Placa, S1
Corsello, G1
Piler, P1
Švancara, J1
Kukla, L1
Pikhart, H1
Good, P1
Ruisch, IH1
Buitelaar, JK1
Glennon, JC1
Hoekstra, PJ1
Dietrich, A1
Shukla, L1
Harshe, D1
Desai, NJ1
Dcruz, M1
Praharaj, SK1
Shukla, A1
Andrade, C3
Gorelik, E1
Reif, S1
McCrae, JC1
Morrison, EE1
MacIntyre, IM1
Dear, JW1
Webb, DJ1
Tapia, G2
Størdal, K2
Mårild, K2
Kahrs, CR2
Skrivarhaug, T1
Njølstad, PR1
Joner, G1
Stene, LC2
Becquet, O1
Bonnet, D1
Ville, Y1
Lapillonne, A1
Sellem, E1
Badiou, S1
Sutra, T1
Cassoulet, R1
Abdelouahab, N1
Serme-Gbedo, YK1
Desautels, AS1
Brennan, KJM1
Burris, HH1
Coull, BA1
Weisskopf, MG2
Brix, N1
Lauridsen, LLB1
Parner, ET1
Olsen, LH1
Schneider, BC1
Del-Ponte, B1
Loret de Mola, C1
Schuler-Faccini, L1
Vianna, FSL1
Munhoz, TN1
Entiauspe, L1
Silveira, MF1
Rohde, LA1
Gou, X1
Wang, Y1
Tang, Y1
Qu, Y1
Tang, J1
Shi, J1
Xiao, D1
Mu, D1
Galletly, C1
Kioumourtzoglou, MA1
Roberts, AL1
O'Reilly, ÉJ1
Ascherio, A1
Nohr, EA1
Morgen, CS1
Sørensen, TIA1
Ask, H1
Eilertsen, E1
Bresnahan, M1
Aase, H1
Mjaaland, S1
Susser, ES1
Thiele, K2
Kessler, T1
Arck, P3
Erhardt, A2
Tiegs, G3
Selgrade, MK1
Blain, RB1
Fedak, KM1
Cawley, MA1
Nulman, I3
Koren, G3
Isling, LK1
Boberg, J2
Jacobsen, PR2
Mandrup, KR1
Axelstad, M1
Christiansen, S1
Vinggaard, AM2
Taxvig, C1
Kortenkamp, A1
Hass, U2
Cannell, JJ1
Cooper, M1
Langley, K1
Thapar, A3
Lee, PC1
Blaser, JA1
Allan, GM1
Karimi, K2
Brune, K1
Nielsen, JK1
Modick, H1
Mørck, TA1
Jensen, JF1
Nielsen, F1
Knudsen, LE1
Amitai, Y1
Weatherall, M3
Ioannides, S1
Braithwaite, I1
Beasley, R3
Pottegård, A1
dePont Christensen, R1
Hallas, J1
Thompson, JM1
Waldie, KE1
Wall, CR1
Murphy, R1
Mitchell, EA1
Cheelo, M1
Lodge, CJ1
Dharmage, SC2
Simpson, JA1
Matheson, M1
Heinrich, J1
Lowe, AJ1
Sordillo, JE1
Scirica, CV1
Gillman, MW1
Bunyavanich, S1
Camargo, CA1
Weiss, ST1
Gold, DR1
Litonjua, AA1
Shaheen, SO6
Keßler, T1
Ramisch, K1
Huebener, P1
Barikbin, R1
de Fays, L1
Van Malderen, K1
De Smet, K1
Sawchik, J1
Verlinden, V1
Hamdani, J1
Dogné, JM1
Dan, B1
Langhendries, JP1
Blecharz-Klin, K3
Joniec-Maciejak, I3
Jawna, K1
Pyrzanowska, J3
Piechal, A3
Wawer, A3
Widy-Tyszkiewicz, E3
Hoover, RM1
Hayes, VA1
Erramouspe, J1
Liu, X1
Pedersen, LH1
Bech, BH1
Agerbo, E1
Yuan, W1
Virk, J2
Holm, JB1
Mazaud-Guittot, S2
Danneskiold-Samsøe, NB1
Chalmey, C1
Jensen, B1
Nørregård, MM1
Hansen, CH1
Styrishave, B1
Svingen, T1
Bowles, J1
Koopman, P1
Magnus, MC1
Karlstad, Ø1
Nafstad, P1
Nystad, W1
Mayor, S1
Gaudriault, P1
Lesné, L2
Serrano, T1
Main, KM3
Källén, B2
Reis, M1
Saad, A1
Hegde, S1
Kechichian, T1
Gamble, P1
Rahman, M1
Stutz, SJ1
Anastasio, NC1
Alshehri, W1
Lei, J1
Mori, S1
Kajs, B1
Cunningham, KA1
Saade, G1
Burd, I1
Costantine, M1
Avella-Garcia, CB1
Fortuny, J1
Galán, IR1
Rodríguez-Bernal, CL1
Stergiakouli, E2
Lourido-Cebreiro, T1
Salgado, FJ1
Valdes, L1
Gonzalez-Barcala, FJ1
Vlenterie, R1
Roeleveld, N1
van Gelder, MM1
Fisher, BG1
Thankamony, A1
Hughes, IA1
Ong, KK1
Dunger, DB1
Acerini, CL1
Jawna-Zboińska, K2
Gallo, V1
Dijk, FN1
Holloway, JW2
Ring, SM2
Koppelman, GH1
Postma, DS1
Strachan, DP2
Granell, R1
de Jongste, JC1
Jaddoe, VW1
den Dekker, HT1
Duijts, L1
Henderson, AJ5
Lind, DV1
Kyhl, HB1
Toppari, J2
Andersen, HR1
Andersen, MS1
Skakkebæk, NE1
Bach, CC1
Asarnow, RF1
Beale, DJ1
Saunders, NR1
Habgood, MD1
Little, MO1
Wickremsinhe, MN1
Lyerly, AD1
Persky, V1
Piorkowski, J1
Hernandez, E1
Chavez, N1
Wagner-Cassanova, C1
Vergara, C1
Pelzel, D1
Enriquez, R1
Gutierrez, S1
Busso, A1
Perzanowski, MS1
Miller, RL2
Tang, D1
Ali, D1
Garfinkel, RS1
Chew, GL1
Goldstein, IF1
Perera, FP1
Barr, RG1
Leeder, JS1
Kang, EM1
Lundsberg, LS1
Illuzzi, JL1
Bracken, MB1
Persky, VW1
Farquhar, H1
Stewart, A1
Mitchell, E1
Crane, J1
Eyers, S2
Newson, RB3
Smith, GD1
Wennergren, G2
Ang, R1
Breitmeyer, J1
Royal, MA1
Rose-Zerilli, MJ1
Lottrup, G1
Desdoits-Lethimonier, C1
Petersen, JH1
Nellemann, C1
Leffers, H1
Bakkeheim, E1
Mowinckel, P1
Carlsen, KH1
Håland, G1
Carlsen, KC1
Gunawardana, L1
Zammit, S1
Lewis, G1
Gunnell, D1
Hollis, C1
Wolke, D1
Harrison, G1
Verd, S1
Nadal-Amat, J1
Jefferies, S1
Allen, KJ1
Garcia-Marcos, L1
Sanchez-Solis, M1
Perez-Fernandez, V1
Jensen, MS1
Henriksen, TB1
Thulstrup, AM1
Toft, G1
Sørensen, HT2
Bonde, JP1
Goksör, E1
Thengilsdottir, H1
Alm, B1
Norvenius, G1
Jedrychowski, W1
Spengler, JD1
Maugeri, U1
Budzyn-Mrozek, D1
Perzanowski, M1
Flak, E1
Mroz, E1
Majewska, R1
Kaim, I1
Perera, F1
Finnström, O1
Nygren, KG1
Otterblad Olausson, P1
Nuttall, SL1
Williams, J1
Kendall, MJ1
Benini, D1
Fanos, V1
Tatò, L1
Headley, JE1
Stratton, FD1
Jones, RW1
Falliers, CJ1
Allmers, H1
Kogevinas, M1
Roberts, I1
Robinson, MJ1
Mughal, MZ1
Ratcliffe, JG1
Prescott, LF1
Sancewicz-Pach, K1
Chmiest, W1
Lichota, E1
AW, MM1
Dhawan, A1
Baker, AJ1
Mieli-Vergani, G1
McElhatton, PR1
Sullivan, FM1
Volans, GN1
Fitzpatrick, R1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Long Term Follow-up of the TREOCAPA (Prophylactic TREatment Of the duCtus Arteriosus in Preterm Infants by Acetaminophen) Study (TREOCAPA-LT)[NCT06064825]500 participants (Anticipated)Observational2023-11-30Not yet recruiting
Early Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study[NCT06025890]2,100 participants (Anticipated)Interventional2022-12-07Recruiting
The Copenhagen Analgesic Study[NCT04369222]600 participants (Anticipated)Observational2020-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

36 reviews available for acetaminophen and Delayed Effects, Prenatal Exposure

ArticleYear
Paracetamol (Acetaminophen) and the Developing Brain.
    International journal of molecular sciences, 2021, Oct-15, Volume: 22, Issue:20

    Topics: Acetaminophen; Adult; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Auti

2021
Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:25

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Ibuprofen;

2022
The safety of pediatric use of paracetamol (acetaminophen): a narrative review of direct and indirect evidence.
    Minerva pediatrics, 2022, Volume: 74, Issue:6

    Topics: Acetaminophen; Animals; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Chi

2022
Acetaminophen use during pregnancy and the risk of attention deficit hyperactivity disorder: A causal association or bias?
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Bias; Child;

2020
Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review.
    The lancet. Psychiatry, 2020, Volume: 7, Issue:11

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Biomarkers; Female; Humans; Pre-Eclamp

2020
Opioid Use and Misuse in Pregnancy.
    Clinics in perinatology, 2020, Volume: 47, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory A

2020
Paracetamol overdose in the newborn and infant: a life-threatening event.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Chemical and Drug Indu

2021
Intrauterine Exposure to Acetaminophen and Adverse Developmental Outcomes: Epidemiological Findings and Methodological Issues.
    Current environmental health reports, 2021, Volume: 8, Issue:1

    Topics: Acetaminophen; Asthma; Child; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effects

2021
Maternal paracetamol intake and fetal ductus arteriosus closure: adding pieces to the scenery.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Ductus Arteriosus, Patent; Female; Humans; Infant, Newborn;

2021
Assessing the impact of in-utero exposures: potential effects of paracetamol on male reproductive development.
    Archives of disease in childhood, 2017, Volume: 102, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Environmental Exposure; Female; Genital Diseases, Male; Hum

2017
Fetal programming of mental health by acetaminophen? Response to the SMFM statement: prenatal acetaminophen use and ADHD.
    Expert opinion on drug safety, 2017, Volume: 16, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Confounding

2017
Is acetaminophen safe in pregnancy?
    Scandinavian journal of pain, 2017, Volume: 17

    Topics: Acetaminophen; Adult; Analgesics; Antipyretics; Child; Female; Humans; Pregnancy; Prenatal Exposure

2017
Prenatal paracetamol exposure and child neurodevelopment: A review.
    Hormones and behavior, 2018, Volume: 101

    Topics: Acetaminophen; Attention; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; C

2018
Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Cohort Studies.
    American journal of epidemiology, 2018, 08-01, Volume: 187, Issue:8

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Female; Huma

2018
Long-term adverse effects of paracetamol - a review.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:10

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Asthma; Cardiovascular Diseases; Chron

2018
Association of maternal prenatal acetaminophen use with the risk of attention deficit/hyperactivity disorder in offspring: A meta-analysis.
    The Australian and New Zealand journal of psychiatry, 2019, Volume: 53, Issue:3

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Pregnancy; Prenatal Ex

2019
Acetaminophen and pregnancy: short- and long-term consequences for mother and child.
    Journal of reproductive immunology, 2013, Volume: 97, Issue:1

    Topics: Acetaminophen; Antipyretics; Child; Female; Fetal Development; Fetus; Humans; Liver; Maternal Exposu

2013
Potential risk of asthma associated with in utero exposure to xenobiotics.
    Birth defects research. Part C, Embryo today : reviews, 2013, Volume: 99, Issue:1

    Topics: Acetaminophen; Adult; Animals; Asthma; Child; Environmental Exposure; Female; Humans; Mice; Pregnanc

2013
New problems arising from old drugs: second-generation effects of acetaminophen.
    Expert review of clinical pharmacology, 2014, Volume: 7, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Asthma; Chemical and Drug Induced Liver Injury; Ch

2014
The association between paracetamol use and asthma: causation or coincidence?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2015, Volume: 45, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Asthma; Child; Child, Preschool; Female;

2015
Paracetamol exposure in pregnancy and early childhood and development of childhood asthma: a systematic review and meta-analysis.
    Archives of disease in childhood, 2015, Volume: 100, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child, Preschool; Female; Humans; Infant; Pregnancy

2015
Use of paracetamol during pregnancy and child neurological development.
    Developmental medicine and child neurology, 2015, Volume: 57, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Attention Deficit Disorder with Hyperactivity; Chi

2015
[Paracetamol (acetaminophen) use in neonatology: a (re)appreciation of an old drug].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2015, Volume: 22, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Cyclooxygenase 2 Inhibitors; Ductus Arteriosus, Patent; Fem

2015
Association Between Prenatal Acetaminophen Exposure and Future Risk of Attention Deficit/Hyperactivity Disorder in Children.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:12

    Topics: Acetaminophen; Analgesics; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, P

2015
Use of acetaminophen (paracetamol) during pregnancy and the risk of autism spectrum disorder in the offspring.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Autism Spectrum Disorder; Female; Humans; Pregnancy; Prenat

2016
Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Commerce;

2016
Ongoing Pharmacological Management of Chronic Pain in Pregnancy.
    Drugs, 2016, Volume: 76, Issue:9

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chr

2016
The association between paracetamol and asthma is still under debate.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2017, 01-02, Volume: 54, Issue:1

    Topics: Acetaminophen; Asthma; Child, Preschool; Female; Glutathione; Humans; Infant; Infant, Newborn; Perox

2017
The role of paracetamol in the pathogenesis of asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2010, Volume: 40, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Asthma; Child; Child, Preschool; Female; Global Heal

2010
Childhood asthma and use during pregnancy of acetaminophen. A critical review.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 30, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antipyretics; Asthma; Child; Child, Preschool; Confounding

2010
Paracetamol in pregnancy and the risk of wheezing in offspring: a systematic review and meta-analysis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child; Female; Humans; Pregnancy; Prenatal Exposure

2011
Early exposure to acetaminophen and allergic disorders.
    Current opinion in allergy and clinical immunology, 2011, Volume: 11, Issue:3

    Topics: Acetaminophen; Asthma; Drug Hypersensitivity; Female; Humans; Maternal Exposure; Pregnancy; Prenatal

2011
Acetaminophen and asthma.
    Paediatric respiratory reviews, 2013, Volume: 14, Issue:1

    Topics: Acetaminophen; Antipyretics; Asthma; Female; Global Health; Humans; Incidence; Pregnancy; Prenatal E

2013
Does paracetamol cause asthma?
    Journal of clinical pharmacy and therapeutics, 2003, Volume: 28, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Asthma; Female; Free Radicals; Glutathione; Humans

2003
Frequent acetaminophen use and allergic diseases: is the association clear?
    The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:4

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Humans; Hypersensit

2005
Paracetamol poisoning in pregnancy: an analysis of the outcomes of cases referred to the Teratology Information Service of the National Poisons Information Service.
    Human & experimental toxicology, 1990, Volume: 9, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Female; Follow-Up Studies; Humans; Infant, Newborn; Info

1990

Other Studies

136 other studies available for acetaminophen and Delayed Effects, Prenatal Exposure

ArticleYear
Caution needed: paracetamol use in pregnancy.
    Nature reviews. Endocrinology, 2021, Volume: 17, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effect

2021
Intrauterine and Lactational Exposure to Paracetamol: Cardiometabolic Evaluation in Adult Female and Male Offspring.
    Journal of cardiovascular pharmacology, 2021, 12-01, Volume: 78, Issue:6

    Topics: Acetaminophen; Adiposity; Analgesics, Non-Narcotic; Animals; Aorta, Thoracic; Cardiovascular Disease

2021
Prenatal Exposure to Acetaminophen and Childhood Asthmatic Symptoms in a Population-Based Cohort in Los Angeles, California.
    International journal of environmental research and public health, 2021, 09-26, Volume: 18, Issue:19

    Topics: Acetaminophen; Asthma; Child; Female; Humans; Los Angeles; Pregnancy; Prenatal Exposure Delayed Effe

2021
Paracetamol use in pregnancy - caution over causal inference from available data.
    Nature reviews. Endocrinology, 2022, Volume: 18, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effect

2022
Reply to 'Paracetamol use in pregnancy - caution over causal inference from available data'; 'Handle with care - interpretation, synthesis and dissemination of data on paracetamol in pregnancy'.
    Nature reviews. Endocrinology, 2022, Volume: 18, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effect

2022
Paracetamol use in pregnancy - neglecting context promotes misinterpretation.
    Nature reviews. Endocrinology, 2022, Volume: 18, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effect

2022
Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures.
    Clinical epigenetics, 2022, 06-28, Volume: 14, Issue:1

    Topics: Acetaminophen; Cohort Studies; DNA Methylation; Female; Fetal Blood; Humans; Norway; Pregnancy; Pren

2022
Maternal acetaminophen use and cognitive development at 4 years: the Ontario Birth Study.
    Pediatric research, 2023, Volume: 93, Issue:4

    Topics: Acetaminophen; Child, Preschool; Cognition; Female; Humans; Ontario; Pregnancy; Prenatal Exposure De

2023
Maternal use of acetaminophen during pregnancy and neurobehavioral problems in offspring at 3 years: A prospective cohort study.
    PloS one, 2022, Volume: 17, Issue:9

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Child, Preschool; Female; Humans; Infa

2022
Associations of prenatal exposure to non-steroidal anti-inflammatory drugs with preterm birth and small for gestational age infants among women with autoimmune disorders.
    Pharmacoepidemiology and drug safety, 2023, Volume: 32, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents; Female; Gestational Age; Humans; Infant; Infant, Newborn; I

2023
Paracetamol use in pregnancy: Not as safe as we may think?
    Acta obstetricia et gynecologica Scandinavica, 2023, Volume: 102, Issue:6

    Topics: Acetaminophen; Child; Female; Fetal Development; Fetus; Humans; Placenta; Pregnancy; Prenatal Exposu

2023
Response: 'Pledging my time: In utero exposure to acetaminophen and childhood neurodevelopment'.
    Paediatric and perinatal epidemiology, 2023, Volume: 37, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child Development; Female; Humans; Prenatal Exposure

2023
Pledging my time: In utero exposure to acetaminophen and childhood neurodevelopment.
    Paediatric and perinatal epidemiology, 2023, Volume: 37, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child Development; Female; Humans; Prenatal Exposure

2023
Prenatal and early-life antibiotic exposure and the risk of atopic dermatitis in children: A nationwide population-based cohort study.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2023, Volume: 34, Issue:5

    Topics: Acetaminophen; Anti-Bacterial Agents; Cohort Studies; Dermatitis, Atopic; Female; Humans; Infant; Pr

2023
Autism spectrum disorder related to unwarranted paracetamol use in pregnancy.
    JPMA. The Journal of the Pakistan Medical Association, 2022, Volume: 72, Issue:12

    Topics: Acetaminophen; Autism Spectrum Disorder; Female; Humans; Pregnancy; Prenatal Exposure Delayed Effect

2022
Course-, dose-, and stage-dependent toxic effects of prenatal acetaminophen exposure on fetal long bone development.
    Toxicology letters, 2023, Sep-15, Volume: 387

    Topics: Acetaminophen; Animals; Bone and Bones; Female; Fetal Development; Humans; Mice; Osteogenesis; Pregn

2023
Prenatal exposure to acetaminophen at different doses, courses and time causes testicular dysplasia in offspring mice and its mechanism.
    Chemosphere, 2023, Volume: 345

    Topics: Acetaminophen; Animals; Female; Humans; Leydig Cells; Male; Mice; Pregnancy; Prenatal Exposure Delay

2023
In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.
    Communications biology, 2019, Volume: 2

    Topics: Acetaminophen; Aging; Animals; Animals, Newborn; Cell Proliferation; Female; Fertility; Forkhead Box

2019
Prenatal paracetamol exposure and neurodevelopmental outcomes in preschool-aged children.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Behavior; Child Behavior Disorders; Child Development

2020
Prenatal Exposure to Acetaminophen and the Risk of Attention-Deficit/Hyperactivity Disorder: A Nationwide Study in Taiwan.
    The Journal of clinical psychiatry, 2019, 09-10, Volume: 80, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Case-

2019
Associations between paracetamol (acetaminophen) intake between 18 and 32 weeks gestation and neurocognitive outcomes in the child: A longitudinal cohort study.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorder

2020
Masarwa et al. Respond to "The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology".
    American journal of epidemiology, 2020, 01-31, Volume: 189, Issue:1

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Cohort Studies; Fem

2020
Invited Commentary: The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology.
    American journal of epidemiology, 2020, 01-31, Volume: 189, Issue:1

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Autistic Dis

2020
Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorder

2020
Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood.
    JAMA psychiatry, 2020, 02-01, Volume: 77, Issue:2

    Topics: Acetaminophen; Adult; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Bioma

2020
Maternal acetaminophen use during pregnancy and childhood behavioural problems: Discrepancies between mother- and teacher-reported outcomes.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorders; Chi

2020
Acetaminophen use in pregnancy: Examining prevalence, timing, and indication of use in a prospective birth cohort.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Arthritis; Behavioral Symptoms; Cohort Studies; Dose

2020
Can maternal exposure to paracetamol impair reproductive parameters of male rat offspring?
    Reproductive toxicology (Elmsford, N.Y.), 2020, Volume: 93

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Female; Hypothalamus; Male; Maternal-Fetal Exchang

2020
Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Brazil; Child Behavior; Child Development; Child, Preschool

2020
Prenatal acetaminophen exposure and neurodevelopment: State of the evidence.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Adaptation, Physiological; Analgesics, Non-Narcotic; Attention Deficit Disorder with

2020
Associations between prenatal acetaminophen exposure and child neurodevelopment: Truth, bias, or a bit of both?
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Bias; Centra

2020
Simple twist of fate: In utero exposure to acetaminophen and risk of childhood Attention Deficit Hyperactivity Disorder.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Bias; Child; Female; Humans; Pregnancy

2020
Low neurodevelopmental performance and behavioural/emotional problems at 24 and 48 months in Brazilian children exposed to acetaminophen during foetal development.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Affective Symptoms; Analgesics, Non-Narcotic; Brazil; Child Behavior; Child Developme

2020
Prenatal exposure to acetaminophen and neurodevelopment.
    Paediatric and perinatal epidemiology, 2020, Volume: 34, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Central Nervous System; Child; Child Development; Female; H

2020
Nature and nurture of sexual partner preference: Teachings from prenatal administration of acetaminophen in male rats.
    Hormones and behavior, 2020, Volume: 124

    Topics: Acetaminophen; Animals; Brain; Choice Behavior; Estradiol; Female; Male; Pregnancy; Prenatal Exposur

2020
Association of Prenatal Acetaminophen Exposure Measured in Meconium With Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity.
    JAMA pediatrics, 2020, 11-01, Volume: 174, Issue:11

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Child; Connectome; Female; Follow-Up S

2020
Behavioral Problems at Age 11 Years After Prenatal and Postnatal Exposure to Acetaminophen: Parent-Reported and Self-Reported Outcomes.
    American journal of epidemiology, 2021, 06-01, Volume: 190, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorders; Cohort Stu

2021
Effect of paracetamol treatment on maternal care and reproductive outcomes in female rat offspring.
    Reproduction, fertility, and development, 2020, Volume: 32, Issue:18

    Topics: Acetaminophen; Animals; Animals, Newborn; Estrous Cycle; Female; Gonadal Steroid Hormones; Male; Mat

2020
Evaluation of hepatic and renal effects in rat dams and their offspring after exposure to paracetamol during gestation and lactation.
    Reproduction, fertility, and development, 2020, Volume: 32, Issue:18

    Topics: Acetaminophen; Animals; Animals, Newborn; Female; Kidney; Lactation; Liver; Male; Maternal Exposure;

2020
Maternal paracetamol intake and fetal ductus arteriosus constriction/closure: comprehensive signal evaluation using the Austin Bradford Hill criteria.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Constriction; Ductus Arteriosus; Female; Humans; Pregnancy;

2021
Prenatal exposure to acetaminophen increases the risk of atopic dermatitis in children: A nationwide nested case-control study in Taiwan.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2021, Volume: 32, Issue:5

    Topics: Acetaminophen; Case-Control Studies; Child; Dermatitis, Atopic; Female; Humans; Pregnancy; Prenatal

2021
Perinatal exposure to paracetamol: Dose and sex-dependent effects in behaviour and brain's oxidative stress markers in progeny.
    Behavioural brain research, 2021, 06-25, Volume: 408

    Topics: Acetaminophen; Animals; Behavior, Animal; Breast Feeding; Central Nervous System Agents; Disease Mod

2021
Prenatal and postnatal exposure to acetaminophen in relation to autism spectrum and attention-deficit and hyperactivity symptoms in childhood: Meta-analysis in six European population-based cohorts.
    European journal of epidemiology, 2021, Volume: 36, Issue:10

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Attention; Attention Deficit Disorder with Hyperacti

2021
Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour.
    Reproduction (Cambridge, England), 2017, Volume: 154, Issue:2

    Topics: Acetaminophen; Aggression; Aniline Compounds; Animals; Ejaculation; Female; Gestational Age; Male; M

2017
Placental Abruption With Delayed Fetal Compromise in Maternal Acetaminophen Toxicity.
    Obstetrics and gynecology, 2017, Volume: 130, Issue:1

    Topics: Abruptio Placentae; Acetaminophen; Adult; Analgesics, Non-Narcotic; Cesarean Section; Diagnosis, Dif

2017
Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD.
    Clinical epigenetics, 2017, Volume: 9

    Topics: Acetaminophen; Adult; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; DNA Methy

2017
Prenatal Exposure to Acetaminophen and Risk of ADHD.
    Pediatrics, 2017, Volume: 140, Issue:5

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity;

2017
An Association Between Prenatal Acetaminophen Use and ADHD: The Benefits of Large Data Sets.
    Pediatrics, 2017, Volume: 140, Issue:5

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Humans; Prenatal Exposure Delayed Effe

2017
Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child.
    International journal of epidemiology, 2018, 02-01, Volume: 47, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Cerebral Palsy; Cohort Studies; Female; Hum

2018
Prenatal exposure to acetaminophen and children's language development at 30 months.
    European psychiatry : the journal of the Association of European Psychiatrists, 2018, Volume: 51

    Topics: Acetaminophen; Adult; Child, Preschool; Cohort Studies; Correlation of Data; Female; Humans; Languag

2018
A Case of Cardiomyopathy Due to Premature Ductus Arteriosus Closure: The Flip Side of Paracetamol.
    Pediatrics, 2018, Volume: 141, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Cardiomyopathies; Diet, Mediterranean; Ductus Arteriosus; F

2018
Role of combined prenatal and postnatal paracetamol exposure on asthma development: the Czech ELSPAC study.
    Journal of epidemiology and community health, 2018, Volume: 72, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child, Preschool; Czech Republic; Female; Humans; I

2018
Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup).
    Clinical nutrition ESPEN, 2018, Volume: 23

    Topics: Acetaminophen; Amoxicillin-Potassium Clavulanate Combination; Androgens; Aromatase; Aromatase Inhibi

2018
Pregnancy risk factors in relation to oppositional-defiant and conduct disorder symptoms in the Avon Longitudinal Study of Parents and Children.
    Journal of psychiatric research, 2018, Volume: 101

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit and Disruptive Behavior Disorders; Child;

2018
Commentary on: Prenatal exposure to acetaminophen and children's language development at 30 months.
    European psychiatry : the journal of the Association of European Psychiatrists, 2018, Volume: 51

    Topics: Acetaminophen; Child; Child Development; Female; Humans; Language Development; Pregnancy; Prenatal E

2018
Reply to: Shukla et al., Commentary on: Prenatal exposure to acetaminophen and children's language development at 30 months.
    European psychiatry : the journal of the Association of European Psychiatrists, 2018, Volume: 51

    Topics: Acetaminophen; Child; Child Development; Female; Humans; Language Development; Pregnancy; Prenatal E

2018
Antibiotics, acetaminophen and infections during prenatal and early life in relation to type 1 diabetes.
    International journal of epidemiology, 2018, 10-01, Volume: 47, Issue:5

    Topics: Acetaminophen; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cohort Studies; Diabetes

2018
Paracetamol/Acetaminophen During Pregnancy Induces Prenatal Ductus Arteriosus Closure.
    Pediatrics, 2018, Volume: 142, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Ductus Arteriosus, Patent; Female; Humans; Infant, Newborn;

2018
Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Embryo, M

2019
FOUR AUTHORS REPLY.
    American journal of epidemiology, 2018, 12-01, Volume: 187, Issue:12

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Cohort Studi

2018
RE: "PRENATAL EXPOSURE TO ACETAMINOPHEN AND RISK FOR ATTENTION DEFICIT HYPERACTIVITY DISORDER AND AUTISTIC SPECTRUM DISORDER: A SYSTEMATIC REVIEW, META-ANALYSIS, AND META-REGRESSION ANALYSIS OF COHORT STUDIES".
    American journal of epidemiology, 2018, 12-01, Volume: 187, Issue:12

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Cohort Studi

2018
Association Between Meconium Acetaminophen and Childhood Neurocognitive Development in GESTE, a Canadian Cohort Study.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, 01-01, Volume: 167, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Canada; Child; Child Development; Child, Preschool; Cogniti

2019
Acetaminophen (Paracetamol) Exposure During Pregnancy and Pubertal Development in Boys and Girls From a Nationwide Puberty Cohort.
    American journal of epidemiology, 2019, 01-01, Volume: 188, Issue:1

    Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Child; Child, Preschool; Cigarette Smokin

2019
Is intrauterine exposure to acetaminophen associated with emotional and hyperactivity problems during childhood? Findings from the 2004 Pelotas birth cohort.
    BMC psychiatry, 2018, 11-20, Volume: 18, Issue:1

    Topics: Acetaminophen; Adult; Affective Symptoms; Age Factors; Brazil; Child; Cohort Studies; Female; Humans

2018
Paracetamol, pregnancy and public health.
    The Australian and New Zealand journal of psychiatry, 2019, Volume: 53, Issue:3

    Topics: Acetaminophen; Adverse Childhood Experiences; Female; Hallucinogens; Humans; Mental Disorders; Pregn

2019
Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses' Health Study II.
    American journal of epidemiology, 2019, 04-01, Volume: 188, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Child

2019
Prenatal Exposure to Acetaminophen and Overweight in Childhood.
    Obesity (Silver Spring, Md.), 2019, Volume: 27, Issue:8

    Topics: Acetaminophen; Child; Child, Preschool; Denmark; Endocrine Disruptors; Female; Humans; Male; Materna

2019
Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder.
    Scientific reports, 2019, 07-02, Volume: 9, Issue:1

    Topics: Acetaminophen; Adult; Attention Deficit Disorder with Hyperactivity; Child; Cohort Studies; Female;

2019
Prenatal and perinatal analgesic exposure and autism: an ecological link.
    Environmental health : a global access science source, 2013, May-09, Volume: 12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child Development Disorders, Pervasive; Circumcision

2013
Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study.
    International journal of epidemiology, 2013, Volume: 42, Issue:6

    Topics: Acetaminophen; Aggression; Analgesics, Non-Narcotic; Anxiety; Case-Control Studies; Child Developmen

2013
Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters.
    Reproduction (Cambridge, England), 2014, Volume: 147, Issue:4

    Topics: Acetaminophen; Aging; Animals; Benzhydryl Compounds; Camphor; Cinnamates; Endocrine Disruptors; Fema

2014
Paracetamol, oxidative stress, vitamin D and autism spectrum disorders.
    International journal of epidemiology, 2014, Volume: 43, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2014
Authors' Response: More research on paracetamol is required.
    International journal of epidemiology, 2014, Volume: 43, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2014
Antenatal acetaminophen use and attention-deficit/hyperactivity disorder: an interesting observed association but too early to infer causality.
    JAMA pediatrics, 2014, Volume: 168, Issue:4

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Hyperkinesis; Male; Me

2014
Acetaminophen use during pregnancy, behavioral problems, and hyperkinetic disorders.
    JAMA pediatrics, 2014, Volume: 168, Issue:4

    Topics: Acetaminophen; Adult; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Denmar

2014
Acetaminophen in pregnancy and future risk of ADHD in offspring.
    Canadian family physician Medecin de famille canadien, 2014, Volume: 60, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Female; Huma

2014
N-acetyl-4-aminophenol (paracetamol) in urine samples of 6-11-year-old Danish school children and their mothers.
    International journal of hygiene and environmental health, 2015, Volume: 218, Issue:1

    Topics: Acetaminophen; Adult; Body Burden; Child; Environmental Monitoring; Female; Humans; Male; Pregnancy;

2015
Characteristics of acetaminophen users compared with nonusers during pregnancy, behavioral problems, and hyperkinetic disorders.
    JAMA pediatrics, 2014, Volume: 168, Issue:9

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Hyperkinesis; Male; Me

2014
Characteristics of acetaminophen users compared with nonusers during pregnancy, behavioral problems, and hyperkinetic disorders--reply.
    JAMA pediatrics, 2014, Volume: 168, Issue:9

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Hyperkinesis; Male; Me

2014
Annotations and reflections: pregnancy and paracetamol: methodological considerations on the study of associations between in utero exposure to drugs and childhood neurodevelopment.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2015
Associations between acetaminophen use during pregnancy and ADHD symptoms measured at ages 7 and 11 years.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Child; Femal

2014
Annotations and reflections: response to "Pregnancy and paracetamol: methodological considerations on the study of associations between in utero exposure to drugs and childhood neurodevelopment".
    Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Development; Female; Humans; Male; Mental Disorders;

2015
Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chi

2015
Acetaminophen and childhood asthma: pill-popping at our peril?
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Hu

2015
Prenatal acetaminophen induces liver toxicity in dams, reduces fetal liver stem cells, and increases airway inflammation in adult offspring.
    Journal of hepatology, 2015, Volume: 62, Issue:5

    Topics: Acetaminophen; Adult; Adult Children; Analgesics, Non-Narcotic; Animals; Asthma; Chemical and Drug I

2015
Mothers-to-be warned over paracetamol.
    Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association, 2015, Volume: 88, Issue:7

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; Fetus; Humans; Male; Pregnancy; Prenatal Exp

2015
Effect of prenatal and early life paracetamol exposure on the level of neurotransmitters in rats--Focus on the spinal cord.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015, Volume: 47, Issue:Pt B

    Topics: Acetaminophen; Age Factors; Alkaline Phosphatase; Amino Acids; Analgesics, Non-Narcotic; Animals; An

2015
Association of prenatal exposure to acetaminophen and coffee with childhood asthma.
    Pharmacoepidemiology and drug safety, 2016, Volume: 25, Issue:2

    Topics: Acetaminophen; Adult; Asthma; Coffee; Cohort Studies; Denmark; Female; Follow-Up Studies; Humans; Pr

2016
Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study.
    Autism research : official journal of the International Society for Autism Research, 2016, Volume: 9, Issue:9

    Topics: Acetaminophen; Adult; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child

2016
Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 150, Issue:1

    Topics: Acetaminophen; Aniline Compounds; Animals; Female; Fertility; Genitalia, Female; Gestational Age; Ma

2016
Prenatal and infant paracetamol exposure and development of asthma: the Norwegian Mother and Child Cohort Study.
    International journal of epidemiology, 2016, Volume: 45, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child, Preschool; Cohort Studies; Female; Humans; I

2016
Paracetamol exposure prenatally and in infancy is linked to asthma, study shows.
    BMJ (Clinical research ed.), 2016, Feb-11, Volume: 352

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Humans; Prenatal Exposure Delayed Effects

2016
Use of acetaminophen (paracetamol) during pregnancy and the risk of attention-deficit/hyperactivity disorder in the offspring.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:3

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Female; Humans; Male; Pregnancy; Prena

2016
Is There a Causal Relation between Maternal Acetaminophen Administration and ADHD?
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Attention Deficit Disorder with Hyperactivity; Bra

2016
Acetaminophen use in pregnancy and neurodevelopment: attention function and autism spectrum symptoms.
    International journal of epidemiology, 2016, 12-01, Volume: 45, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Attention; Autism Spectrum Disorder; Child Developme

2016
Maternal Infections, Antibiotics, and Paracetamol in Pregnancy and Offspring Celiac Disease: A Cohort Study.
    Journal of pediatric gastroenterology and nutrition, 2017, Volume: 64, Issue:5

    Topics: Acetaminophen; Anti-Bacterial Agents; Celiac Disease; Child; Female; Follow-Up Studies; Humans; Logi

2017
Prenatal Use of Acetaminophen and Child IQ: A Danish Cohort Study.
    Epidemiology (Cambridge, Mass.), 2016, Volume: 27, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child, Preschool; Female; Humans; Intellectual Disab

2016
Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding.
    JAMA pediatrics, 2016, Oct-01, Volume: 170, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Child; Child

2016
Neurodevelopmental problems at 18 months among children exposed to paracetamol in utero: a propensity score matched cohort study.
    International journal of epidemiology, 2016, 12-01, Volume: 45, Issue:6

    Topics: Acetaminophen; Adult; Aggression; Analgesics, Non-Narcotic; Child Development; Cohort Studies; Commu

2016
Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants.
    Human reproduction (Oxford, England), 2016, Volume: 31, Issue:11

    Topics: Acetaminophen; Anal Canal; Biomarkers; Body Weights and Measures; Female; Humans; Infant, Newborn; M

2016
Cerebellar level of neurotransmitters in rats exposed to paracetamol during development.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Cerebellum; Chromatography, High

2016
TRPA1 gene polymorphisms and childhood asthma.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2017, Volume: 28, Issue:2

    Topics: Acetaminophen; Asthma; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Genetic Associat

2017
Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother-child pairs.
    Human reproduction (Oxford, England), 2017, Volume: 32, Issue:1

    Topics: Acetaminophen; Adult; Anal Canal; Analgesics; Anthropometry; Anti-Inflammatory Agents, Non-Steroidal

2017
Paracetamol use during pregnancy and attention and executive function in offspring at age 5 years.
    International journal of epidemiology, 2016, 12-01, Volume: 45, Issue:6

    Topics: Acetaminophen; Adult; Attention; Attention Deficit Disorder with Hyperactivity; Child Development; C

2016
Prenatal acetaminophen use and outcomes in children.
    American journal of obstetrics and gynecology, 2017, Volume: 216, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Fever; Humans; Neurodevelo

2017
Paracetamol - Effect of early exposure on neurotransmission, spatial memory and motor performance in rats.
    Behavioural brain research, 2017, 04-14, Volume: 323

    Topics: Acetaminophen; Amino Acids; Analgesics, Non-Narcotic; Animals; Biogenic Monoamines; Brain; Explorato

2017
Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment.
    JAMA pediatrics, 2017, 04-01, Volume: 171, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Humans; Pregnancy; Prenatal Exposure Delayed

2017
Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment.
    JAMA pediatrics, 2017, 04-01, Volume: 171, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Humans; Pregnancy; Prenatal Exposure Delayed

2017
Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment.
    JAMA pediatrics, 2017, 04-01, Volume: 171, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Humans; Pregnancy; Prenatal Exposure Delayed

2017
Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment.
    JAMA pediatrics, 2017, 04-01, Volume: 171, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Humans; Pregnancy; Prenatal Exposure Delayed

2017
Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment-Reply.
    JAMA pediatrics, 2017, 04-01, Volume: 171, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Female; Humans; Pregnancy; Prenatal Exposure Delayed

2017
Prenatal exposure to acetaminophen and respiratory symptoms in the first year of life.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2008, Volume: 101, Issue:3

    Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Asthma; Breast Feeding; Cough; Female; H

2008
Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort.
    Thorax, 2010, Volume: 65, Issue:2

    Topics: Acetaminophen; Allergens; Analgesics, Non-Narcotic; Asthma; Child, Preschool; Female; Genetic Predis

2010
Developmental pharmacogenetics: a general paradigm for application to neonatal pharmacology and toxicology.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzhydryl Compounds; Environmental Pollutants; Female; Gas

2009
Prenatal exposure to acetaminophen and asthma in children.
    Obstetrics and gynecology, 2009, Volume: 114, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Asthma; Child; Female; Humans; Pregnancy; Prenatal E

2009
Acetaminophen and asthma.
    Thorax, 2010, Volume: 65, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child; Female; Humans; Maternal-Fetal Exchange; Pre

2010
Prenatal paracetamol exposure and asthma: further evidence against confounding.
    International journal of epidemiology, 2010, Volume: 39, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child; Confounding Factors, Epidemiologic; Female;

2010
Paracetamol – accumulating reports of an association with allergy and asthma.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:1

    Topics: Acetaminophen; Antipyretics; Asthma; Child; Female; Humans; Hypersensitivity; Infant; Pregnancy; Pre

2011
Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma.
    The Journal of allergy and clinical immunology, 2010, Volume: 126, Issue:6

    Topics: Acetaminophen; Asthma; Female; Genotype; Glutathione Transferase; Humans; Inactivation, Metabolic; I

2010
Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.
    Human reproduction (Oxford, England), 2011, Volume: 26, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cohort Studies; Cryptorchidism; Female; Humans; Ibuprof

2011
Paracetamol in early infancy: the risk of childhood allergy and asthma.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:1

    Topics: Acetaminophen; Asthma; Child; Female; Follow-Up Studies; Humans; Hypersensitivity; Infant; Male; Pre

2011
Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence.
    Schizophrenia research, 2011, Volume: 126, Issue:1-3

    Topics: Acetaminophen; Analgesics; Aspirin; Child; Cohort Studies; Confounding Factors, Epidemiologic; Delus

2011
Paracetamol and asthma and lactation.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Breast Feeding; Female; Humans; Infant; Infant, New

2011
Does regular paracetamol ingestion increase the risk of developing asthma?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child; Female; Humans; Meta-Analysis as Topic; Preg

2011
Analgesics during pregnancy and cryptorchidism: additional analyses.
    Epidemiology (Cambridge, Mass.), 2011, Volume: 22, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Cryptorchidism; Cyclooxygenase Inhibitors; Female;

2011
Prenatal paracetamol exposure and risk of wheeze at preschool age.
    Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:12

    Topics: Acetaminophen; Administration, Inhalation; Adrenal Cortex Hormones; Child, Preschool; Female; Humans

2011
Effect of prenatal exposure to fine particulate matter and intake of Paracetamol (Acetaminophen) in pregnancy on eczema occurrence in early childhood.
    The Science of the total environment, 2011, Nov-15, Volume: 409, Issue:24

    Topics: Acetaminophen; Adult; Air Pollutants; Analgesics, Non-Narcotic; Child; Cohort Studies; Eczema; Femal

2011
Maternal drug use during pregnancy and asthma risk among children.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2013, Volume: 24, Issue:1

    Topics: Acetaminophen; Analgesics, Opioid; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Child; Child

2013
In utero exposure to nonsteroidal anti-inflammatory drugs: neonatal renal failure.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:2

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Fema

2004
Gastroschisis and pseudoephedrine during pregnancy.
    Prescrire international, 2004, Volume: 13, Issue:72

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenergic Agents; Case-Control Studies; Ephedrine; Fema

2004
Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; As

2005
Emergent asthma: endogenous, exogenous, or iatrogenous.
    Chest, 2005, Volume: 127, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Child, Preschool; Cross-Secti

2005
Pre-natal exposure to paracetamol and risk of wheezing and asthma in children: a birth cohort study.
    International journal of epidemiology, 2008, Volume: 37, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Asthma; Bronchitis; Child; Denmark; Epidemiologic Methods; Female;

2008
Paracetamol metabolites in the neonate following maternal overdose.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:2

    Topics: Acetaminophen; Adult; Female; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Pregnancy;

1984
Suicidal paracetamol poisoning of a pregnant woman just before a delivery.
    Przeglad lekarski, 1999, Volume: 56, Issue:6

    Topics: Acetaminophen; Adult; Aspartate Aminotransferases; Drug Overdose; Female; Humans; Infant, Newborn; I

1999
Neonatal paracetamol poisoning.
    Archives of disease in childhood. Fetal and neonatal edition, 1999, Volume: 81, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Analgesics, Non-Narcotic; Female; Free Radical Scavengers

1999