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acetaminophen and Deficiency of Glucose-6-Phosphate Dehydrogenase

acetaminophen has been researched along with Deficiency of Glucose-6-Phosphate Dehydrogenase in 12 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Patients with glucose-6-phosphate dehydrogenase deficiency who overdose with acetaminophen should be monitored for the possible development of subsequent drug-induced hemolysis."8.79Hemolysis after acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency. ( Perry, HE; Shannon, MW; Woolf, AD; Wright, RO, 1996)
"Fever and concomitant infection, through an increment of erythrocyte glutathione depletion, sensitized the infant to the haemolytic event."5.37Acute haemolytic crisis due to concomitant presence of infection and possible altered acetaminophen catabolism in a Philipino child carrying the G6PD-Vanua Lava mutation. ( Capoluongo, E; Concolino, P; De Luca, D; Giardina, B; Maurizi, P; Minucci, A; Torti, E; Zuppi, C, 2011)
"Acetaminophen was the most likely cause of the hemolysis."5.31Hemolysis as a potential complication of acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency. ( Sklar, GE, 2002)
"Patients with glucose-6-phosphate dehydrogenase deficiency who overdose with acetaminophen should be monitored for the possible development of subsequent drug-induced hemolysis."4.79Hemolysis after acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency. ( Perry, HE; Shannon, MW; Woolf, AD; Wright, RO, 1996)
"Aldose reductase catalyzes the NADPH-linked reduction of hexoses to their respective sugar-alcohols, which are involved in the pathogenesis of "sugar-cataracts"."3.68Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies. ( Alvarez, A; Chávez, M; Chávez-Anaya, E; Medina, C; Medina, MD; Mendoza, R; Ramírez, MG; Sáenz, G; Vaca, G; Vargas, M, 1992)
"Paracetamol-induced haemolysis in G6PD deficiency is a rare complication and mostly reported in children."1.40Glucose-6-phosphate dehydrogenase deficiency: an unusual cause of acute jaundice after paracetamol overdose. ( Phillpotts, S; Sen, S; Tash, E, 2014)
"Fever and concomitant infection, through an increment of erythrocyte glutathione depletion, sensitized the infant to the haemolytic event."1.37Acute haemolytic crisis due to concomitant presence of infection and possible altered acetaminophen catabolism in a Philipino child carrying the G6PD-Vanua Lava mutation. ( Capoluongo, E; Concolino, P; De Luca, D; Giardina, B; Maurizi, P; Minucci, A; Torti, E; Zuppi, C, 2011)
"Acetaminophen was the most likely cause of the hemolysis."1.31Hemolysis as a potential complication of acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency. ( Sklar, GE, 2002)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Phillpotts, S1
Tash, E1
Sen, S1
Rickner, SS1
Cao, D1
Simpson, SE1
Minucci, A1
De Luca, D1
Torti, E1
Concolino, P1
Maurizi, P1
Giardina, B1
Zuppi, C1
Capoluongo, E1
Beutler, E1
Bartsocas, CS1
Schulman, JD1
Corash, L1
Wright, RO1
Perry, HE1
Woolf, AD1
Shannon, MW1
Oliver, M1
Coton, T1
Badens, C1
Dehan, C1
Lena-Russo, D1
Moalic, JL1
Sklar, GE1
Vaca, G1
Ramírez, MG1
Vargas, M1
Mendoza, R1
Chávez-Anaya, E1
Medina, MD1
Alvarez, A1
Medina, C1
Sáenz, G1
Chávez, M1
Heintz, B1
Bock, TA1
Kierdorf, H1
Maurin, N1
Ahmed, I1
Olowe, O1

Reviews

1 review available for acetaminophen and Deficiency of Glucose-6-Phosphate Dehydrogenase

ArticleYear
Hemolysis after acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; H

1996

Other Studies

11 other studies available for acetaminophen and Deficiency of Glucose-6-Phosphate Dehydrogenase

ArticleYear
Glucose-6-phosphate dehydrogenase deficiency: an unusual cause of acute jaundice after paracetamol overdose.
    European journal of haematology, 2014, Volume: 93, Issue:5

    Topics: Acetaminophen; Acute Disease; Adult; Antipyretics; Drug Overdose; Female; Glucosephosphate Dehydroge

2014
Hemolytic crisis following acetaminophen overdose in a patient with G6PD deficiency.
    Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anemia, Hemolytic; Drug Overdose; Female; Glucosepho

2017
Acute haemolytic crisis due to concomitant presence of infection and possible altered acetaminophen catabolism in a Philipino child carrying the G6PD-Vanua Lava mutation.
    Annals of clinical biochemistry, 2011, Volume: 48, Issue:Pt 3

    Topics: Acetaminophen; Child, Preschool; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Defi

2011
Acetamonophen and G-6-PD deficiency.
    Acta haematologica, 1984, Volume: 72, Issue:3

    Topics: Acetaminophen; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans

1984
Can acetaminophen cause hemolysis in G6PD deficiency?
    Acta haematologica, 1982, Volume: 67, Issue:3

    Topics: Acetaminophen; Adult; Anemia, Hemolytic; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Human

1982
Homozygous G6PD deficiency and propacetamol induced hemolysis.
    Haematologica, 2001, Volume: 86, Issue:9

    Topics: Acetaminophen; Adult; Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Female; Glucosepho

2001
Hemolysis as a potential complication of acetaminophen overdose in a patient with glucose-6-phosphate dehydrogenase deficiency.
    Pharmacotherapy, 2002, Volume: 22, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Cell Count; Glucosephosphate Dehydrogenase Def

2002
Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies.
    Archives of medical research, 1992,Spring, Volume: 23, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Animals; Black People

1992
Glucose-6-phosphate dehydrogenase deficiency.
    The New England journal of medicine, 1991, Jun-13, Volume: 324, Issue:24

    Topics: Acetaminophen; Dapsone; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Humans

1991
Haemolytic crisis after acetaminophen in glucose-(6)-phosphate dehydrogenase deficiency.
    Klinische Wochenschrift, 1989, Oct-17, Volume: 67, Issue:20

    Topics: Acetaminophen; Adult; Anemia, Hemolytic; Glucosephosphate Dehydrogenase Deficiency; Hemoglobinuria;

1989
Haemoglobinuria in Nigerian children.
    The African journal of medical sciences, 1971, Volume: 2, Issue:2

    Topics: Acetaminophen; Aspirin; Autopsy; Brain; Caffeine; Child; Child, Preschool; Coombs Test; Diagnosis, D

1971