acetaminophen has been researched along with Cystic Fibrosis in 11 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we present the case of a cystic fibrosis (CF) patient with preserved pulmonary function who developed acute liver failure requiring liver transplant following an episode of binge drinking and ingestion of a modest amount of acetaminophen." | 8.31 | Acute Liver Failure Triggered by Therapeutic Dose of Acetaminophen in a Patient with Cystic Fibrosis. ( Goodman, A; Grenn, EE; Koller, FL; Petrasek, J, 2023) |
| "The disposition of acetaminophen after oral administration was investigated in adults with cystic fibrosis (n = 5) and in age-matched healthy control subjects (n = 5)." | 7.68 | Disposition of drugs in cystic fibrosis. III. Acetaminophen. ( Aitken, ML; Hutabarat, RM; Kushmerick, P; Slattery, JT; Smith, AL; Unadkat, JD, 1991) |
| "Patients with cystic fibrosis are more likely to have glutathione deficiency, and greater susceptibility to liver injury." | 5.48 | Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity. ( Cheung, B; Gantier, M; Graudins, A; Nejad, C; Wong, A, 2018) |
| "Here we present the case of a cystic fibrosis (CF) patient with preserved pulmonary function who developed acute liver failure requiring liver transplant following an episode of binge drinking and ingestion of a modest amount of acetaminophen." | 4.31 | Acute Liver Failure Triggered by Therapeutic Dose of Acetaminophen in a Patient with Cystic Fibrosis. ( Goodman, A; Grenn, EE; Koller, FL; Petrasek, J, 2023) |
| "The disposition of acetaminophen after oral administration was investigated in adults with cystic fibrosis (n = 5) and in age-matched healthy control subjects (n = 5)." | 3.68 | Disposition of drugs in cystic fibrosis. III. Acetaminophen. ( Aitken, ML; Hutabarat, RM; Kushmerick, P; Slattery, JT; Smith, AL; Unadkat, JD, 1991) |
| "Patients with cystic fibrosis are more likely to have glutathione deficiency, and greater susceptibility to liver injury." | 1.48 | Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity. ( Cheung, B; Gantier, M; Graudins, A; Nejad, C; Wong, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Goodman, A | 1 |
| Grenn, EE | 1 |
| Koller, FL | 1 |
| Petrasek, J | 1 |
| Wong, A | 1 |
| Cheung, B | 1 |
| Nejad, C | 1 |
| Gantier, M | 1 |
| Graudins, A | 1 |
| Selbst, SM | 1 |
| Osterhoudt, K | 1 |
| Smith, KJ | 1 |
| Elidemir, O | 1 |
| Dishop, MK | 1 |
| Eldin, KW | 1 |
| Tatevian, N | 1 |
| Moore, RH | 1 |
| Atkuri, KR | 1 |
| Mantovani, JJ | 1 |
| Herzenberg, LA | 2 |
| Edwards, L | 1 |
| Symon, DN | 1 |
| Gray, ES | 1 |
| Hanmer, OJ | 1 |
| Russell, G | 1 |
| Kulkarni, SG | 1 |
| Pegram, AA | 1 |
| Smith, PC | 1 |
| Weinberger, MM | 1 |
| Hutabarat, RM | 1 |
| Unadkat, JD | 1 |
| Kushmerick, P | 1 |
| Aitken, ML | 1 |
| Slattery, JT | 1 |
| Smith, AL | 1 |
| Pennington, JE | 1 |
1 review available for acetaminophen and Cystic Fibrosis
| Article | Year |
|---|---|
N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Controlled Clinical Trials as Topic; Cysteine; Cystic Fibr | 2007 |
1 trial available for acetaminophen and Cystic Fibrosis
| Article | Year |
|---|---|
Preliminary investigations of Pseudomonas aeruginosa vaccine in patients with leukemia and cystic fibrosis.
Topics: Acetaminophen; Administration, Oral; Adult; Antibodies, Bacterial; Bacterial Vaccines; Child; Clinic | 1974 |
9 other studies available for acetaminophen and Cystic Fibrosis
| Article | Year |
|---|---|
Acute Liver Failure Triggered by Therapeutic Dose of Acetaminophen in a Patient with Cystic Fibrosis.
Topics: Acetaminophen; Cystic Fibrosis; Humans; Liver Cirrhosis; Liver Diseases; Liver Failure, Acute; Lung; | 2023 |
Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Adult; Antidotes; Biomarkers; Chemical and Drug Induced Liver Injury; | 2018 |
Pediatric emergency medicine: legal briefs.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Appendicitis; | 2012 |
Intravenous injection of pharmaceutical tablets presenting as multiple pulmonary nodules and declining pulmonary function in an adolescent with cystic fibrosis.
Topics: Acetaminophen; Adolescent; Cystic Fibrosis; Diagnosis, Differential; Drug Combinations; Embolism; Ex | 2006 |
Hyperprolactinaemia in a patient with cystic fibrosis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Cystic Fibrosis; Domperidone; Drug Combination | 2007 |
Fatal paracetamol poisoning from benorylate therapy in child with cystic fibrosis.
Topics: Acetaminophen; Arthritis, Juvenile; Child, Preschool; Cystic Fibrosis; Humans; Male; Salicylates | 1982 |
Disposition of acetaminophen and indocyanine green in cystic fibrosis-knockout mice.
Topics: Acetaminophen; Animals; Cystic Fibrosis; Indocyanine Green; Male; Mice; Mice, Knockout; Models, Anim | 2000 |
Drug clearance in patients with cystic fibrosis.
Topics: Acetaminophen; Body Surface Area; Body Weight; Cystic Fibrosis; Humans; Metabolic Clearance Rate | 1992 |
Disposition of drugs in cystic fibrosis. III. Acetaminophen.
Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Chromatography, High Pressure Liqu | 1991 |