Page last updated: 2024-10-22

acetaminophen and Cystic Fibrosis of Pancreas

acetaminophen has been researched along with Cystic Fibrosis of Pancreas in 11 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Here we present the case of a cystic fibrosis (CF) patient with preserved pulmonary function who developed acute liver failure requiring liver transplant following an episode of binge drinking and ingestion of a modest amount of acetaminophen."8.31Acute Liver Failure Triggered by Therapeutic Dose of Acetaminophen in a Patient with Cystic Fibrosis. ( Goodman, A; Grenn, EE; Koller, FL; Petrasek, J, 2023)
"The disposition of acetaminophen after oral administration was investigated in adults with cystic fibrosis (n = 5) and in age-matched healthy control subjects (n = 5)."7.68Disposition of drugs in cystic fibrosis. III. Acetaminophen. ( Aitken, ML; Hutabarat, RM; Kushmerick, P; Slattery, JT; Smith, AL; Unadkat, JD, 1991)
"Patients with cystic fibrosis are more likely to have glutathione deficiency, and greater susceptibility to liver injury."5.48Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity. ( Cheung, B; Gantier, M; Graudins, A; Nejad, C; Wong, A, 2018)
"Here we present the case of a cystic fibrosis (CF) patient with preserved pulmonary function who developed acute liver failure requiring liver transplant following an episode of binge drinking and ingestion of a modest amount of acetaminophen."4.31Acute Liver Failure Triggered by Therapeutic Dose of Acetaminophen in a Patient with Cystic Fibrosis. ( Goodman, A; Grenn, EE; Koller, FL; Petrasek, J, 2023)
"The disposition of acetaminophen after oral administration was investigated in adults with cystic fibrosis (n = 5) and in age-matched healthy control subjects (n = 5)."3.68Disposition of drugs in cystic fibrosis. III. Acetaminophen. ( Aitken, ML; Hutabarat, RM; Kushmerick, P; Slattery, JT; Smith, AL; Unadkat, JD, 1991)
"Patients with cystic fibrosis are more likely to have glutathione deficiency, and greater susceptibility to liver injury."1.48Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity. ( Cheung, B; Gantier, M; Graudins, A; Nejad, C; Wong, A, 2018)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Goodman, A1
Grenn, EE1
Koller, FL1
Petrasek, J1
Wong, A1
Cheung, B1
Nejad, C1
Gantier, M1
Graudins, A1
Selbst, SM1
Osterhoudt, K1
Smith, KJ1
Elidemir, O1
Dishop, MK1
Eldin, KW1
Tatevian, N1
Moore, RH1
Atkuri, KR1
Mantovani, JJ1
Herzenberg, LA2
Edwards, L1
Symon, DN1
Gray, ES1
Hanmer, OJ1
Russell, G1
Kulkarni, SG1
Pegram, AA1
Smith, PC1
Weinberger, MM1
Hutabarat, RM1
Unadkat, JD1
Kushmerick, P1
Aitken, ML1
Slattery, JT1
Smith, AL1
Pennington, JE1

Reviews

1 review available for acetaminophen and Cystic Fibrosis of Pancreas

ArticleYear
N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency.
    Current opinion in pharmacology, 2007, Volume: 7, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Antidotes; Controlled Clinical Trials as Topic; Cysteine; Cystic Fibr

2007

Trials

1 trial available for acetaminophen and Cystic Fibrosis of Pancreas

ArticleYear
Preliminary investigations of Pseudomonas aeruginosa vaccine in patients with leukemia and cystic fibrosis.
    The Journal of infectious diseases, 1974, Volume: 130 Suppl, Issue:0

    Topics: Acetaminophen; Administration, Oral; Adult; Antibodies, Bacterial; Bacterial Vaccines; Child; Clinic

1974

Other Studies

9 other studies available for acetaminophen and Cystic Fibrosis of Pancreas

ArticleYear
Acute Liver Failure Triggered by Therapeutic Dose of Acetaminophen in a Patient with Cystic Fibrosis.
    The American surgeon, 2023, Volume: 89, Issue:4

    Topics: Acetaminophen; Cystic Fibrosis; Humans; Liver Cirrhosis; Liver Diseases; Liver Failure, Acute; Lung;

2023
Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity.
    Clinical toxicology (Philadelphia, Pa.), 2018, Volume: 56, Issue:10

    Topics: Acetaminophen; Acetylcysteine; Adult; Antidotes; Biomarkers; Chemical and Drug Induced Liver Injury;

2018
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2012, Volume: 28, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Appendicitis;

2012
Intravenous injection of pharmaceutical tablets presenting as multiple pulmonary nodules and declining pulmonary function in an adolescent with cystic fibrosis.
    Pediatrics, 2006, Volume: 118, Issue:3

    Topics: Acetaminophen; Adolescent; Cystic Fibrosis; Diagnosis, Differential; Drug Combinations; Embolism; Ex

2006
Hyperprolactinaemia in a patient with cystic fibrosis.
    British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Cystic Fibrosis; Domperidone; Drug Combination

2007
Fatal paracetamol poisoning from benorylate therapy in child with cystic fibrosis.
    Lancet (London, England), 1982, Nov-20, Volume: 2, Issue:8308

    Topics: Acetaminophen; Arthritis, Juvenile; Child, Preschool; Cystic Fibrosis; Humans; Male; Salicylates

1982
Disposition of acetaminophen and indocyanine green in cystic fibrosis-knockout mice.
    AAPS pharmSci, 2000, Volume: 2, Issue:2

    Topics: Acetaminophen; Animals; Cystic Fibrosis; Indocyanine Green; Male; Mice; Mice, Knockout; Models, Anim

2000
Drug clearance in patients with cystic fibrosis.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:1

    Topics: Acetaminophen; Body Surface Area; Body Weight; Cystic Fibrosis; Humans; Metabolic Clearance Rate

1992
Disposition of drugs in cystic fibrosis. III. Acetaminophen.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:6

    Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Chromatography, High Pressure Liqu

1991