Page last updated: 2024-10-22

acetaminophen and Curling Ulcer

acetaminophen has been researched along with Curling Ulcer in 17 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Curling Ulcer: Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns.

Research Excerpts

ExcerptRelevanceReference
"Misoprostol (Mi, a double blind study in the treatment of active duodenal ulcer (DU)."9.05[A double-blind study with misoprostol in the treatment of active duodenal ulcer]. ( Arguto, JF; Boffi, A; Ciccia, JE; Colombato, LO; Cosen, JN; Luis, A; Mazure, PA, 1985)
"The distribution of mucosal PGE2-like activity was determined by bioassay technique in the body and antrum of the stomach and in the duodenum of healthy subjects and duodenal ulcer patients before and after administration of aspirin, paracetamol, or histamine."7.66Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol. ( Kiec-Dembinska, A; Konturek, SJ; Obtulowicz, W; Oleksy, J; Sito, E; Wilkon, S, 1981)
"The rate of gastric ulcers in subjects receiving paracetamol (0/21, 0%) alone or aspirin (3/19, 16%) or both (2/20, 10%) was not different."5.16Does concomitant use of paracetamol potentiate the gastroduodenal mucosal injury associated with aspirin? A prospective, randomised, pilot study. ( Berkes, J; Boike, JR; Goldstein, JL; Kao, R; Markle, B; Meyer, D; Niebruegge, J; Rosenberg, J; Stein, AC, 2012)
"Misoprostol (Mi, a double blind study in the treatment of active duodenal ulcer (DU)."5.05[A double-blind study with misoprostol in the treatment of active duodenal ulcer]. ( Arguto, JF; Boffi, A; Ciccia, JE; Colombato, LO; Cosen, JN; Luis, A; Mazure, PA, 1985)
"Aspirin is generally regarded as a cause of gastric ulcer but the role of non-steroidal anti-inflammatory agents and paracetamol in the aetiology of peptic ulcer is unclear."3.67Peptic ulcer and non-steroidal anti-inflammatory agents. ( Dobson, AJ; Duggan, JM; Fahey, P; Johnson, H, 1986)
"The distribution of mucosal PGE2-like activity was determined by bioassay technique in the body and antrum of the stomach and in the duodenum of healthy subjects and duodenal ulcer patients before and after administration of aspirin, paracetamol, or histamine."3.66Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol. ( Kiec-Dembinska, A; Konturek, SJ; Obtulowicz, W; Oleksy, J; Sito, E; Wilkon, S, 1981)
"(R)- flurbiprofen was not statistically significant."2.69Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)- ketoprofen, (R)- flurbiprofen, racemic ketoprofen, and paracetamol: a randomized, single-blind, placebo-controlled trial. ( Caubet, JF; Handley, DA; Jerussi, TP; McCray, JE, 1998)
"Chronic gastric ulcer is linked to aspirin intake in patients with rheumatic disease, and epidemiologically in all heavy aspirin users; paradoxically, in only one epidemiologic study was a significant association found between acetaminophen intake and chronic gastric ulcer."2.36Gastrointestinal effects of antipyretic analgesics. ( Ivey, KJ, 1983)
"Aspirin alone was the least frequently ingested."1.26Analgesic ingestion and chronic peptic ulcer. ( Ariotti, DE; Fenton, BH; MacLennan, R; McIntosh, JH; Piper, DW, 1981)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's3 (17.65)18.2507
2000's2 (11.76)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Plamboeck, A1
Veedfald, S1
Deacon, CF1
Hartmann, B1
Wettergren, A1
Svendsen, LB1
Meisner, S1
Hovendal, C1
Knop, FK1
Vilsbøll, T1
Holst, JJ1
Boike, JR1
Kao, R1
Meyer, D1
Markle, B1
Rosenberg, J1
Niebruegge, J1
Stein, AC1
Berkes, J1
Goldstein, JL1
Hochberg, MC1
Brandt, K1
Ivey, KJ1
Konturek, SJ1
Obtulowicz, W1
Sito, E1
Oleksy, J1
Wilkon, S1
Kiec-Dembinska, A1
Piper, DW2
McIntosh, JH2
Ariotti, DE1
Fenton, BH1
MacLennan, R1
Jerussi, TP1
Caubet, JF1
McCray, JE1
Handley, DA1
Harasawa, S2
Tani, N1
Suzuki, S1
Miwa, M1
Sakita, R1
Nomiyama, T1
Miwa, T1
Goodman, MJ1
Kent, PW1
Truelove, SC1
Miller, DR1
Shiina, Y1
Hasebe, T1
Koizumi, F1
Kawamura, T1
Ishimori, A1
Ebina, H1
Satoh, M1
Fung, CS1
Berry, G1
Vendemiale, G1
Altomare, E1
Trizio, T1
Leandro, G1
Manghisi, OG1
Albano, O1
Duggan, JM1
Dobson, AJ1
Johnson, H1
Fahey, P1
Mazure, PA1
Cosen, JN1
Ciccia, JE1
Colombato, LO1
Luis, A1
Arguto, JF1
Boffi, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Significances of Intact Vagal Innervation for the Glucose and GLP1 Induced Insulin Secretion[NCT01176760]30 participants (Anticipated)Interventional2009-08-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for acetaminophen and Curling Ulcer

ArticleYear
New directions in symptomatic therapy for patients with osteoarthritis and rheumatoid arthritis.
    Seminars in arthritis and rheumatism, 2002, Volume: 32, Issue:3 Suppl 1

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2; Cyc

2002
[Paracetamol in the treatment of osteoarthritis pain].
    Drugs, 2003, Volume: 63 Spec No 2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxyg

2003
Gastrointestinal effects of antipyretic analgesics.
    The American journal of medicine, 1983, Nov-14, Volume: 75, Issue:5A

    Topics: Acetaminophen; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonate

1983

Trials

4 trials available for acetaminophen and Curling Ulcer

ArticleYear
Characterisation of oral and i.v. glucose handling in truncally vagotomised subjects with pyloroplasty.
    European journal of endocrinology, 2013, Volume: 169, Issue:2

    Topics: Acetaminophen; Adamantane; Aged; Area Under Curve; Case-Control Studies; Dipeptidyl-Peptidase IV Inh

2013
Does concomitant use of paracetamol potentiate the gastroduodenal mucosal injury associated with aspirin? A prospective, randomised, pilot study.
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster

2012
Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)- ketoprofen, (R)- flurbiprofen, racemic ketoprofen, and paracetamol: a randomized, single-blind, placebo-controlled trial.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:2S

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Duodenal Dise

1998
[A double-blind study with misoprostol in the treatment of active duodenal ulcer].
    Acta gastroenterologica Latinoamericana, 1985, Volume: 15, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Alprostadil; Anti-Ulcer Agents; Clinical Trials

1985

Other Studies

10 other studies available for acetaminophen and Curling Ulcer

ArticleYear
Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol.
    Gut, 1981, Volume: 22, Issue:4

    Topics: Acetaminophen; Adult; Aspirin; Duodenal Ulcer; Duodenum; Gastric Mucosa; Histamine; Humans; Intestin

1981
Analgesic ingestion and chronic peptic ulcer.
    Gastroenterology, 1981, Volume: 80, Issue:3

    Topics: Acetaminophen; Analgesics; Aspirin; Australia; Duodenal Ulcer; Female; Humans; Male; Peptic Ulcer; R

1981
Gastric emptying in normal subjects and patients with peptic ulcer: a study using the acetaminophen method.
    Gastroenterologia Japonica, 1979, Volume: 14, Issue:1

    Topics: Acetaminophen; Adult; Duodenal Ulcer; Gastric Emptying; Humans; Male; Middle Aged; Stomach Ulcer; Ti

1979
Inhibition of glucosamine synthesis by salicylates, hydrocortisone and two non-ulcerogenic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 226, Issue:1

    Topics: Acetaminophen; Aspirin; Carbohydrate Epimerases; Duodenal Ulcer; Gastric Mucosa; Gentamicins; Glutam

1977
Treatment options for a patient with osteoarthritis and a history of ulcer disease.
    Clinical pharmacy, 1991, Volume: 10, Issue:10

    Topics: Acetaminophen; Administration, Oral; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Comb

1991
[Non-ulcer dyspepsia].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:2

    Topics: Acetaminophen; Adenosine Triphosphate; Adult; Aged; Duodenal Ulcer; Dyspepsia; Gastric Acid; Gastric

1991
Plasma paracetamol concentrations measured by fluorescence polarization immunoassay and gastric emptying time.
    The Tohoku journal of experimental medicine, 1988, Volume: 155, Issue:2

    Topics: Acetaminophen; Duodenal Ulcer; Fluorescent Antibody Technique; Gastric Emptying; Gastritis; Humans;

1988
Smoking, nonsteroidal anti-inflammatory drugs, and acetaminophen in gastric ulcer. A study of associations and of the effects of previous diagnosis on exposure patterns.
    American journal of epidemiology, 1988, Volume: 128, Issue:4

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Duodenal Ulc

1988
Effect of acute and chronic cimetidine administration on acetaminophen metabolism in humans.
    The American journal of gastroenterology, 1987, Volume: 82, Issue:10

    Topics: Acetaminophen; Administration, Oral; Adult; Cimetidine; Drug Evaluation; Drug Interactions; Duodenal

1987
Peptic ulcer and non-steroidal anti-inflammatory agents.
    Gut, 1986, Volume: 27, Issue:8

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Aspirin; Duodenal Ulcer; Female; Humans; Male; Middle

1986