Page last updated: 2024-10-22

acetaminophen and Coronary Artery Disease

acetaminophen has been researched along with Coronary Artery Disease in 4 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Research Excerpts

ExcerptRelevanceReference
"The 33 patients with coronary artery disease included in this randomized, double-blind, placebo-controlled, crossover study received acetaminophen (1 g TID) on top of standard cardiovascular therapy for 2 weeks."9.14Acetaminophen increases blood pressure in patients with coronary artery disease. ( Corti, R; Enseleit, F; Flammer, AJ; Gay, S; Haile, SR; Hermann, M; Hirt, A; Holzmeister, J; Hurlimann, D; Kaiser, P; Landmesser, U; Lüscher, TF; Mocharla, P; Neidhart, M; Noll, G; Nussberger, J; Périat, D; Ruschitzka, F; Sudano, I; Vanhoutte, PM; Wolfrum, M, 2010)
"The purpose of this nationwide cohort study was to investigate the incidence and risk of coronary artery disease (CAD) in patients with acetaminophen (APAP) poisoning."7.88Acetaminophen Poisoning May Increase Coronary Artery Disease Risk: A Nationwide Cohort Study. ( Chen, WK; Chou, CY; Chung, WS; Chung, YT; Lin, CL; Tsai, WC, 2018)
"The 33 patients with coronary artery disease included in this randomized, double-blind, placebo-controlled, crossover study received acetaminophen (1 g TID) on top of standard cardiovascular therapy for 2 weeks."5.14Acetaminophen increases blood pressure in patients with coronary artery disease. ( Corti, R; Enseleit, F; Flammer, AJ; Gay, S; Haile, SR; Hermann, M; Hirt, A; Holzmeister, J; Hurlimann, D; Kaiser, P; Landmesser, U; Lüscher, TF; Mocharla, P; Neidhart, M; Noll, G; Nussberger, J; Périat, D; Ruschitzka, F; Sudano, I; Vanhoutte, PM; Wolfrum, M, 2010)
"The purpose of this nationwide cohort study was to investigate the incidence and risk of coronary artery disease (CAD) in patients with acetaminophen (APAP) poisoning."3.88Acetaminophen Poisoning May Increase Coronary Artery Disease Risk: A Nationwide Cohort Study. ( Chen, WK; Chou, CY; Chung, WS; Chung, YT; Lin, CL; Tsai, WC, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Javaherforooshzadeh, F1
Abdalbeygi, H1
Janatmakan, F1
Gholizadeh, B1
Chung, YT1
Chou, CY1
Tsai, WC1
Chen, WK1
Lin, CL1
Chung, WS1
Sudano, I1
Flammer, AJ1
Périat, D1
Enseleit, F1
Hermann, M1
Wolfrum, M1
Hirt, A1
Kaiser, P1
Hurlimann, D1
Neidhart, M1
Gay, S1
Holzmeister, J1
Nussberger, J1
Mocharla, P1
Landmesser, U1
Haile, SR1
Corti, R1
Vanhoutte, PM1
Lüscher, TF1
Noll, G1
Ruschitzka, F1
Nguyen, QV1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Open-label Study Investigating the Effect of Bilateral Renal Artery Sympathetic Denervation by Catheter-based Radiofrequency Ablation on Blood Pressure and Disease Progression in Autosomal Dominant Polycystic Kidney Disease[NCT01932450]Phase 2100 participants (Anticipated)Interventional2013-08-31Recruiting
Paracetamol and Endothelial Function in Patients With Stable Coronary Artery Disease[NCT00534651]Phase 437 participants (Actual)Interventional2006-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for acetaminophen and Coronary Artery Disease

ArticleYear
Comparing the effects of ketorolac and Paracetamol on postoperative pain relief after coronary artery bypass graft surgery. A randomized clinical trial.
    Journal of cardiothoracic surgery, 2020, May-11, Volume: 15, Issue:1

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Coronary Artery Bypass; Coronary Artery Disease; Doub

2020
Acetaminophen increases blood pressure in patients with coronary artery disease.
    Circulation, 2010, Nov-02, Volume: 122, Issue:18

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Circadian Rhythm; Coro

2010
Acetaminophen increases blood pressure in patients with coronary artery disease.
    Circulation, 2010, Nov-02, Volume: 122, Issue:18

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Circadian Rhythm; Coro

2010
Acetaminophen increases blood pressure in patients with coronary artery disease.
    Circulation, 2010, Nov-02, Volume: 122, Issue:18

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Circadian Rhythm; Coro

2010
Acetaminophen increases blood pressure in patients with coronary artery disease.
    Circulation, 2010, Nov-02, Volume: 122, Issue:18

    Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Circadian Rhythm; Coro

2010

Other Studies

2 other studies available for acetaminophen and Coronary Artery Disease

ArticleYear
Acetaminophen Poisoning May Increase Coronary Artery Disease Risk: A Nationwide Cohort Study.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:4

    Topics: Acetaminophen; Adult; Age Factors; Analgesics, Non-Narcotic; Case-Control Studies; Comorbidity; Coro

2018
Letter by Nguyen regarding article, "Acetaminophen increases blood pressure in patients with coronary artery disease".
    Circulation, 2011, Jun-28, Volume: 123, Issue:25

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Blood Pressure; Cardiovascular Diseases; Coronary Artery Di

2011