acetaminophen has been researched along with Complications, Pregnancy in 93 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 9.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "Acetaminophen (APAP) is the most common drug overdose in pregnancy." | 8.82 | Acetaminophen overdose in pregnancy. ( Clark, LE; Herrera, JL; Wilkes, JM, 2005) |
| "Although acetaminophen is commonly used in pregnancy, it can deplete glutathione concentrations and cause accumulation of 5-oxoproline, with subsequent metabolic acidosis." | 8.02 | Malnourishment-Associated Acetaminophen Toxicity in Pregnancy. ( Dom, AM; Olson-Chen, C; Royzer, R, 2021) |
| "Approximately 60% (n = 354) of women reported use of acetaminophen during pregnancy." | 7.96 | Maternal acetaminophen use during pregnancy and childhood behavioural problems: Discrepancies between mother- and teacher-reported outcomes. ( Collett, BR; Parker, SE; Werler, MM, 2020) |
| "Acetaminophen is used by the majority of pregnant women, and some continue to use for many weeks in pregnancy." | 7.96 | Acetaminophen use in pregnancy: Examining prevalence, timing, and indication of use in a prospective birth cohort. ( Bandoli, G; Chambers, C; Palmsten, K, 2020) |
| "Over-the-counter analgesic use during pregnancy, particularly acetaminophen, may be associated with negative developmental outcomes in children." | 7.96 | Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood. ( Bassani, DG; Bertoldi, AD; Boing, AC; da Silva Dal Pizzol, T; Domingues, MR; Freitas Silveira, M; Miranda, VIA; Oken, E; Rifas-Shiman, SL; Santos, IS; Silveira, MPT; Tovo-Rodrigues, L, 2020) |
| "Acetaminophen use was assessed by questionnaire completion at 18 and 32 weeks of pregnancy and when the child was 61 months old." | 7.83 | Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding. ( Davey Smith, G; Stergiakouli, E; Thapar, A, 2016) |
| "The combination of acute fatty liver of pregnancy and acetaminophen toxicity resulted in acute liver failure." | 7.71 | Acute fatty liver of pregnancy and acetaminophen toxicity leading to liver failure and postpartum liver transplantation. A case report. ( Contos, MJ; Gill, EJ; Peng, TC, 2002) |
| "A 38-year-old woman whose pregnancy was at 31 weeks' gestational age was evaluated for treatment of an acetaminophen overdose." | 7.69 | Acetaminophen poisoning in late pregnancy. A case report. ( Chao, HT; Hung, JH; Lee, WL; Wang, PH; Yang, MJ; Yang, ML, 1997) |
| " A case of NAS due to codeine prescribed for pain relief during pregnancy is reported." | 7.69 | Neonatal abstinence syndrome due to codeine. ( Chang, J; Khan, K, 1997) |
| " We conclude that future studies are urgently needed to reconsider the safety and dosage of APAP during pregnancy and - based on the advances made in the field of reproduction as well as APAP metabolism - we propose pathways, which should be addressed in future research and clinical endeavors." | 6.49 | Acetaminophen and pregnancy: short- and long-term consequences for mother and child. ( Arck, P; Erhardt, A; Kessler, T; Thiele, K; Tiegs, G, 2013) |
| " Intravenous acetaminophen, with its increased bioavailability and more rapid onset of action, may have benefit in the intrapartum setting by reducing adverse neonatal and maternal outcomes associated with febrile morbidity." | 5.46 | Intravenous acetaminophen for the treatment of intrapartum fever and resolution of fetal tachycardia: a novel use for an old medication. ( Burgess, APH; Lakhi, N; Moretti, M; Ope-Adenuga, S; Reilly, JG, 2017) |
| "(1) Gastroschisis is a severe defect in the closure of the abdominal wall in newborns." | 5.32 | Gastroschisis and pseudoephedrine during pregnancy. ( , 2004) |
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 5.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "To compare the efficiency of transcutaneous electrical nerve stimulation (TENS) with those of exercise and acetaminophen for the treatment of pregnancy-related low back pain (LBP) during the third trimester of pregnancy." | 5.16 | Transcutaneous electrical nerve stimulation improves low back pain during pregnancy. ( Gumus, II; Kafali, H; Keskin, EA; Keskin, HL; Onur, O; Turhan, N, 2012) |
| " Evidence of association was convincing (class I) for maternal pre-pregnancy obesity (OR 1·63, 95% CI 1·49 to 1·77), childhood eczema (1·31, 1·20 to 1·44), hypertensive disorders during pregnancy (1·29, 1·22 to 1·36), pre-eclampsia (1·28, 1·21 to 1·35), and maternal acetaminophen exposure during pregnancy (RR 1·25, 95% CI 1·17 to 1·34)." | 5.05 | Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review. ( Brunoni, AR; Carvalho, AF; Dragioti, E; Fornaro, M; Fusar-Poli, P; Grabovac, I; Hong, SH; Jacob, L; Jeong, GH; Kim, JH; Kim, JY; Koyanagi, A; Kronbichler, A; Lee, E; Lee, J; Lee, KH; Lee, S; Oh, H; Radua, J; Rais, TB; Salazar de Pablo, G; Schuch, F; Shin, JI; Smith, L; Solmi, M; Stickley, A; Stubbs, B; Thompson, T; Yang, L, 2020) |
| " For a long time, acetaminophen was considered as a relatively safe antipyretic and analgesic drug during pregnancy." | 4.88 | Prenatal tolerability of acetaminophen and other over-the-counter non-selective cyclooxygenase inhibitors. ( Burdan, F; Starosławska, E; Szumiło, J, 2012) |
| " In Europe and North America a large proportion of cases are due to acetaminophen and to idiosyncratic drug reactions, whereas reports from emerging countries in Asia and Africa feature viral illnesses, particularly hepatitis B and E." | 4.84 | Etiologies of acute liver failure. ( Lee, WM, 2008) |
| "Acetaminophen (APAP) is the most common drug overdose in pregnancy." | 4.82 | Acetaminophen overdose in pregnancy. ( Clark, LE; Herrera, JL; Wilkes, JM, 2005) |
| "Although acetaminophen is commonly used in pregnancy, it can deplete glutathione concentrations and cause accumulation of 5-oxoproline, with subsequent metabolic acidosis." | 4.02 | Malnourishment-Associated Acetaminophen Toxicity in Pregnancy. ( Dom, AM; Olson-Chen, C; Royzer, R, 2021) |
| "Examine associations of acetaminophen and ibuprofen use during pregnancy and infancy with executive function and behaviour problems in children." | 3.96 | Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour. ( Bertoldi, AD; Cardenas, A; Hivert, MF; Oken, E; Rifas-Shiman, SL; Tiemeier, H, 2020) |
| "Approximately 60% (n = 354) of women reported use of acetaminophen during pregnancy." | 3.96 | Maternal acetaminophen use during pregnancy and childhood behavioural problems: Discrepancies between mother- and teacher-reported outcomes. ( Collett, BR; Parker, SE; Werler, MM, 2020) |
| "Acetaminophen is used by the majority of pregnant women, and some continue to use for many weeks in pregnancy." | 3.96 | Acetaminophen use in pregnancy: Examining prevalence, timing, and indication of use in a prospective birth cohort. ( Bandoli, G; Chambers, C; Palmsten, K, 2020) |
| "The majority of epidemiological studies concerning possible adverse effects of paracetamol (acetaminophen) in pregnancy have been focussed on childhood asthma." | 3.96 | Associations between paracetamol (acetaminophen) intake between 18 and 32 weeks gestation and neurocognitive outcomes in the child: A longitudinal cohort study. ( Clark, R; Ellis, G; Golding, J; Gregory, S; Iles-Caven, Y; Northstone, K, 2020) |
| " Acetaminophen use during pregnancy was retrospectively assessed at the perinatal follow-up." | 3.96 | Low neurodevelopmental performance and behavioural/emotional problems at 24 and 48 months in Brazilian children exposed to acetaminophen during foetal development. ( Anselmi, L; Barros, AJD; Barros, FC; Bertoldi, AD; Carpena, MX; Martins-Silva, T; Matijasevich, A; Santos, IS; Tovo-Rodrigues, L, 2020) |
| "Over-the-counter analgesic use during pregnancy, particularly acetaminophen, may be associated with negative developmental outcomes in children." | 3.96 | Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood. ( Bassani, DG; Bertoldi, AD; Boing, AC; da Silva Dal Pizzol, T; Domingues, MR; Freitas Silveira, M; Miranda, VIA; Oken, E; Rifas-Shiman, SL; Santos, IS; Silveira, MPT; Tovo-Rodrigues, L, 2020) |
| "Among 2291 women, 932 (41%) reported the use of acetaminophen medications during the current pregnancy." | 3.91 | Comparison of fetal growth by maternal prenatal acetaminophen use. ( Bever, A; Bible, J; Buck Louis, GM; Gerlanc, N; Grantz, KL; Smarr, MM, 2019) |
| "Acetaminophen use was assessed by questionnaire completion at 18 and 32 weeks of pregnancy and when the child was 61 months old." | 3.83 | Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding. ( Davey Smith, G; Stergiakouli, E; Thapar, A, 2016) |
| "The combination of acute fatty liver of pregnancy and acetaminophen toxicity resulted in acute liver failure." | 3.71 | Acute fatty liver of pregnancy and acetaminophen toxicity leading to liver failure and postpartum liver transplantation. A case report. ( Contos, MJ; Gill, EJ; Peng, TC, 2002) |
| "In the population based Avon Longitudinal Study of Parents and Children (ALSPAC) women were asked twice during pregnancy (at 18-20 weeks and 32 weeks) about their usage of paracetamol and aspirin." | 3.71 | Paracetamol use in pregnancy and wheezing in early childhood. ( Burney, PG; Golding, J; Henderson, AJ; Heron, JE; Newson, RB; Shaheen, SO; Sherriff, A, 2002) |
| " A case of NAS due to codeine prescribed for pain relief during pregnancy is reported." | 3.69 | Neonatal abstinence syndrome due to codeine. ( Chang, J; Khan, K, 1997) |
| "A 38-year-old woman whose pregnancy was at 31 weeks' gestational age was evaluated for treatment of an acetaminophen overdose." | 3.69 | Acetaminophen poisoning in late pregnancy. A case report. ( Chao, HT; Hung, JH; Lee, WL; Wang, PH; Yang, MJ; Yang, ML, 1997) |
| "Acetaminophen is a common drug used in pregnancy." | 3.67 | Maternal acetaminophen overdose at 15 weeks of gestation. ( Gabbe, SG; Landon, MB; Ludmir, J; Main, DM, 1986) |
| "The rate of pregnant women with an opioid use disorder has risen drastically in the past 20 years, paralleling that in the general population." | 2.66 | Opioid Use and Misuse in Pregnancy. ( Landau, R; Shatil, B, 2020) |
| "Pain during pregnancy is common, and its management is complex." | 2.61 | Medication Use and Pain Management in Pregnancy: A Critical Review. ( Black, E; Chutatape, A; Demirkol, A; Kennedy, D; Khor, KE; Sharma, S; Vancaillie, T, 2019) |
| " This article presents different analgesic drugs, their mode of action, indications, dosage and adverse drug reactions." | 2.58 | [Pharmacological Basis of Pain Treatment]. ( Schüning, J; Schwarzer, A, 2018) |
| "Many cases of acute liver failure are caused by pregnancy-related conditions such as acute fatty liver of pregnancy and HELLP syndrome." | 2.53 | Liver Failure in Pregnancy. ( Bacak, SJ; Thornburg, LL, 2016) |
| "For a woman with chronic pain, adequate use of pain killers during pregnancy is needed." | 2.53 | Ongoing Pharmacological Management of Chronic Pain in Pregnancy. ( Källén, B; Reis, M, 2016) |
| " Potential links to adverse short- and long-term infant outcomes for these products are reviewed, and the strengths and limitations of data to support these." | 2.52 | Over-the-counter medications: Risk and safety in pregnancy. ( Chambers, C, 2015) |
| " We conclude that future studies are urgently needed to reconsider the safety and dosage of APAP during pregnancy and - based on the advances made in the field of reproduction as well as APAP metabolism - we propose pathways, which should be addressed in future research and clinical endeavors." | 2.49 | Acetaminophen and pregnancy: short- and long-term consequences for mother and child. ( Arck, P; Erhardt, A; Kessler, T; Thiele, K; Tiegs, G, 2013) |
| "Migraine is a typical "women's disease": the fluctuations of sex hormones, in particular estrogens, during woman's reproductive life show a direct and major influence on migraine course." | 2.42 | [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. ( Airola, G; Allais, G; Benedetto, C; Bosio, A; Ciochetto, D; De Lorenzo, C; Mana, O; Quirico, PE; Terzi, MG, 2003) |
| "Pharmacotherapy in pregnancy is often problematic, since both the mother-to-be and her doctor are often concerned about possible risks for the unborn child." | 2.42 | [Drug therapy in pregnancy--a practical guide]. ( Kreienberg, R; Paulus, W; Reister, F, 2004) |
| "The occurrence of migraine in women is influenced by hormonal changes throughout the lifecycle." | 2.40 | Migraine in pregnancy: what are the safest treatment options? ( Pfaffenrath, V; Rehm, M, 1998) |
| " The teratogenic potential of a drug is related to dosage and time of administration." | 2.36 | Analgesics during pregnancy. ( Niederhoff, H; Zahradnik, HP, 1983) |
| "Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population." | 1.51 | Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. ( Hamilton, KT; Robbins, MS, 2019) |
| " Intravenous acetaminophen, with its increased bioavailability and more rapid onset of action, may have benefit in the intrapartum setting by reducing adverse neonatal and maternal outcomes associated with febrile morbidity." | 1.46 | Intravenous acetaminophen for the treatment of intrapartum fever and resolution of fetal tachycardia: a novel use for an old medication. ( Burgess, APH; Lakhi, N; Moretti, M; Ope-Adenuga, S; Reilly, JG, 2017) |
| "Women with migraine stop or switch medications during pregnancy." | 1.46 | Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine. ( Eberhard-Gran, M; Harris, GE; Lundqvist, C; Nordeng, H; Wood, M, 2017) |
| "(1) Gastroschisis is a severe defect in the closure of the abdominal wall in newborns." | 1.32 | Gastroschisis and pseudoephedrine during pregnancy. ( , 2004) |
| "Gastroschisis and small intestinal atresia (SIA) are birth defects that are thought to arise from vascular disruption of fetal mesenteric vessels." | 1.31 | Maternal medication use and risks of gastroschisis and small intestinal atresia. ( Mitchell, AA; Sheehan, JE; Werler, MM, 2002) |
| "We report a case of arthrogryposis multiplex congenita secondary to fetal hypokinesia in a 41-week gestation infant following antenatal central nervous system injury." | 1.30 | Arthrogryposis multiplex congenita and bilateral mid-brain infarction following maternal overdose of co-proxamol. ( Battin, M; Counsell, SJ; Maalouf, EF; Manzur, AY; Rutherford, MA, 1997) |
| "Sixty-nine children with first febrile seizures and no history of previous unprovoked seizures were matched for age (+/- 6 months), site of routine pediatric care, and date of visit (+/- 2 weeks) with 1 or 2 febrile controls who had no history of previous febrile or unprovoked seizures." | 1.29 | Risk factors for a first febrile seizure: a matched case-control study. ( Berg, AT; Crain, EF; Hauser, WA; Salomon, ME; Shapiro, ED; Shinnar, S, 1995) |
| "No pregnancy was adversely affected, but symptoms of pseudotumor increased in 9 of 11 pregnancies." | 1.28 | Pseudotumor cerebri and pregnancy. ( Cefalo, RC; Katz, VL; Peterson, R, 1989) |
| "In patients with preeclampsia the renal excretion of beta 2-microglobulin allows to differentiate between a primary preeclampsia and a preeclampsia superimposed upon chronic pyelonephritis." | 1.26 | Beta 2-microglobulin and other proteins as parameter for tubular function. ( Jaques, G; Keller, M; Mondorf, AW; Prüfer, D; Weise, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (16.13) | 18.7374 |
| 1990's | 14 (15.05) | 18.2507 |
| 2000's | 19 (20.43) | 29.6817 |
| 2010's | 34 (36.56) | 24.3611 |
| 2020's | 11 (11.83) | 2.80 |
| Authors | Studies |
|---|---|
| Trønnes, JN | 1 |
| Wood, M | 2 |
| Lupattelli, A | 1 |
| Ystrom, E | 1 |
| Nordeng, H | 2 |
| Golding, J | 2 |
| Gregory, S | 1 |
| Clark, R | 1 |
| Ellis, G | 1 |
| Iles-Caven, Y | 1 |
| Northstone, K | 1 |
| Rifas-Shiman, SL | 2 |
| Cardenas, A | 1 |
| Hivert, MF | 1 |
| Tiemeier, H | 1 |
| Bertoldi, AD | 3 |
| Oken, E | 2 |
| Parker, SE | 1 |
| Collett, BR | 1 |
| Werler, MM | 2 |
| Bandoli, G | 1 |
| Palmsten, K | 1 |
| Chambers, C | 2 |
| Boing, AC | 1 |
| da Silva Dal Pizzol, T | 1 |
| Miranda, VIA | 1 |
| Silveira, MPT | 1 |
| Freitas Silveira, M | 1 |
| Domingues, MR | 1 |
| Santos, IS | 2 |
| Bassani, DG | 1 |
| Tovo-Rodrigues, L | 2 |
| Carpena, MX | 1 |
| Martins-Silva, T | 1 |
| Anselmi, L | 1 |
| Barros, AJD | 1 |
| Barros, FC | 1 |
| Matijasevich, A | 1 |
| Kim, JH | 1 |
| Kim, JY | 1 |
| Lee, J | 1 |
| Jeong, GH | 1 |
| Lee, E | 1 |
| Lee, S | 1 |
| Lee, KH | 1 |
| Kronbichler, A | 1 |
| Stubbs, B | 1 |
| Solmi, M | 1 |
| Koyanagi, A | 1 |
| Hong, SH | 1 |
| Dragioti, E | 1 |
| Jacob, L | 1 |
| Brunoni, AR | 1 |
| Carvalho, AF | 1 |
| Radua, J | 1 |
| Thompson, T | 1 |
| Smith, L | 1 |
| Oh, H | 1 |
| Yang, L | 1 |
| Grabovac, I | 1 |
| Schuch, F | 1 |
| Fornaro, M | 1 |
| Stickley, A | 1 |
| Rais, TB | 1 |
| Salazar de Pablo, G | 1 |
| Shin, JI | 1 |
| Fusar-Poli, P | 1 |
| Shatil, B | 1 |
| Landau, R | 1 |
| Adane, F | 1 |
| Seyoum, G | 1 |
| Alamneh, YM | 1 |
| Dom, AM | 1 |
| Royzer, R | 1 |
| Olson-Chen, C | 1 |
| Harris, GE | 1 |
| Eberhard-Gran, M | 1 |
| Lundqvist, C | 1 |
| Abu, MA | 1 |
| Abdul Ghani, NA | 1 |
| Shan, LP | 1 |
| Sulaiman, AS | 1 |
| Omar, MH | 1 |
| Ariffin, MHM | 1 |
| Baharuddin, A | 1 |
| Shohaimi, S | 1 |
| Man, ZC | 1 |
| Jarvis, S | 1 |
| Dassan, P | 1 |
| Piercy, CN | 1 |
| Ope-Adenuga, S | 1 |
| Burgess, APH | 1 |
| Reilly, JG | 1 |
| Moretti, M | 1 |
| Lakhi, N | 1 |
| Childress, KMS | 1 |
| Dothager, C | 1 |
| Gavard, JA | 1 |
| Lebovitz, S | 1 |
| Laska, C | 1 |
| Mostello, DJ | 1 |
| Schüning, J | 1 |
| Schwarzer, A | 1 |
| Hamilton, KT | 1 |
| Robbins, MS | 1 |
| Smarr, MM | 1 |
| Bible, J | 1 |
| Gerlanc, N | 1 |
| Buck Louis, GM | 1 |
| Bever, A | 1 |
| Grantz, KL | 1 |
| Kiernan, E | 1 |
| Jones, KL | 1 |
| Kushner, T | 1 |
| Tholey, D | 1 |
| Dodge, J | 1 |
| Saberi, B | 1 |
| Schiano, T | 1 |
| Terrault, N | 1 |
| Black, E | 1 |
| Khor, KE | 1 |
| Kennedy, D | 1 |
| Chutatape, A | 1 |
| Sharma, S | 1 |
| Vancaillie, T | 1 |
| Demirkol, A | 1 |
| Thiele, K | 1 |
| Kessler, T | 1 |
| Arck, P | 2 |
| Erhardt, A | 1 |
| Tiegs, G | 2 |
| Xue, P | 2 |
| Tu, C | 1 |
| Wang, K | 1 |
| Wang, X | 1 |
| Fang, Y | 1 |
| Clemente-Fuentes, RJ | 1 |
| Pickett, H | 1 |
| Carney, M | 1 |
| Sharma, K | 1 |
| Goel, A | 1 |
| Garg, M | 1 |
| Gupta, D | 1 |
| Christensen, C | 1 |
| Soskin, V | 1 |
| Karimi, K | 1 |
| Brune, K | 1 |
| Mayooran, N | 1 |
| O'Cathain, E | 1 |
| Bresnihan, MN | 1 |
| Patil, N | 1 |
| Bacak, SJ | 1 |
| Thornburg, LL | 1 |
| Fatori Popovic, S | 1 |
| Lübbers, HT | 1 |
| von Mandach, U | 1 |
| Källén, B | 2 |
| Reis, M | 1 |
| Stergiakouli, E | 1 |
| Thapar, A | 1 |
| Davey Smith, G | 1 |
| Devkota, R | 1 |
| Khan, GM | 1 |
| Alam, K | 1 |
| Regmi, A | 1 |
| Sapkota, B | 1 |
| Hultzsch, S | 1 |
| Schaefer, C | 1 |
| Adukauskiene, D | 1 |
| Dockiene, I | 1 |
| Naginiene, R | 1 |
| Kevelaitis, E | 1 |
| Pundzius, J | 1 |
| Kupcinskas, L | 1 |
| Garcia-Marcos, L | 1 |
| Sanchez-Solis, M | 1 |
| Perez-Fernandez, V | 1 |
| Pastor-Vivero, MD | 1 |
| Mondejar-Lopez, P | 1 |
| Valverde-Molina, J | 1 |
| Østensen, M | 1 |
| Förger, F | 1 |
| Leroux, P | 1 |
| Hennebert, C | 1 |
| Catteau, J | 1 |
| Legros, H | 1 |
| Hennebert, O | 1 |
| Laudenbach, V | 1 |
| Marret, S | 1 |
| Payen, C | 1 |
| Cossa, S | 1 |
| Riethmuller, D | 1 |
| Picod, G | 1 |
| Clair, D | 1 |
| Descotes, J | 1 |
| Hurault-Delarue, C | 1 |
| Lacroix, I | 1 |
| Vidal, S | 1 |
| Montastruc, JL | 1 |
| Damase-Michel, C | 1 |
| Keskin, EA | 1 |
| Onur, O | 1 |
| Keskin, HL | 1 |
| Gumus, II | 1 |
| Kafali, H | 1 |
| Turhan, N | 1 |
| Burdan, F | 1 |
| Starosławska, E | 1 |
| Szumiło, J | 1 |
| Valap, S | 1 |
| Millns, P | 1 |
| Bulchandani, S | 1 |
| Finnström, O | 1 |
| Nygren, KG | 1 |
| Otterblad Olausson, P | 1 |
| Gill, EJ | 1 |
| Contos, MJ | 1 |
| Peng, TC | 1 |
| Shaheen, SO | 1 |
| Newson, RB | 1 |
| Sherriff, A | 1 |
| Henderson, AJ | 1 |
| Heron, JE | 1 |
| Burney, PG | 1 |
| Pérez-Molina, JJ | 1 |
| Alfaro-Alfaro, N | 1 |
| Ochoa-Ponce, C | 1 |
| HARLEY, JD | 1 |
| FARRAR, JF | 1 |
| GRAY, JB | 1 |
| DUNLOP, IC | 1 |
| Allais, G | 1 |
| Bosio, A | 1 |
| Mana, O | 1 |
| Airola, G | 1 |
| Ciochetto, D | 1 |
| Terzi, MG | 1 |
| De Lorenzo, C | 1 |
| Quirico, PE | 1 |
| Benedetto, C | 1 |
| Reister, F | 1 |
| Paulus, W | 1 |
| Kreienberg, R | 1 |
| Guerreiro da Silva, JB | 1 |
| Nakamura, MU | 1 |
| Cordeiro, JA | 1 |
| Kulay, L | 1 |
| Gandhi, H | 1 |
| Davies, N | 1 |
| Czeizel, AE | 1 |
| Dudás, I | 1 |
| Puhó, E | 1 |
| Wilkes, JM | 1 |
| Clark, LE | 1 |
| Herrera, JL | 1 |
| McKinney, J | 1 |
| Weintraub, A | 1 |
| Mankuta, D | 1 |
| Wong, CA | 1 |
| McCarthy, RJ | 1 |
| Fitzgerald, PC | 1 |
| Raikoff, K | 1 |
| Avram, MJ | 1 |
| Lee, WM | 1 |
| Weise, M | 1 |
| Prüfer, D | 1 |
| Jaques, G | 1 |
| Keller, M | 1 |
| Mondorf, AW | 1 |
| Gabbe, SG | 2 |
| Niederhoff, H | 1 |
| Zahradnik, HP | 1 |
| Ruthnum, P | 1 |
| Goel, KM | 2 |
| Williams, DA | 1 |
| Weiss, T | 1 |
| Wade, E | 1 |
| Dignan, P | 1 |
| Stokes, IM | 1 |
| Byer, AJ | 1 |
| Traylor, TR | 1 |
| Semmer, JR | 1 |
| Berg, AT | 1 |
| Shinnar, S | 1 |
| Shapiro, ED | 1 |
| Salomon, ME | 1 |
| Crain, EF | 1 |
| Hauser, WA | 1 |
| Oldhafer, KJ | 1 |
| Gubernatis, G | 1 |
| Schlitt, HJ | 1 |
| Rodeck, B | 1 |
| Böker, K | 1 |
| Pichlmayr, R | 1 |
| Jákó, J | 1 |
| Arató, G | 1 |
| Davies, MH | 1 |
| Ngong, JM | 1 |
| Yucesoy, M | 1 |
| Acharya, SK | 1 |
| Mills, CO | 1 |
| Weaver, JB | 1 |
| Waring, RH | 1 |
| Elias, E | 1 |
| Nappi, C | 1 |
| Nolfe, G | 1 |
| La Pinta, M | 1 |
| Colace, G | 1 |
| Ruotolo, C | 1 |
| Affinito, P | 1 |
| Khan, K | 1 |
| Chang, J | 1 |
| Wang, PH | 1 |
| Yang, MJ | 1 |
| Lee, WL | 1 |
| Chao, HT | 1 |
| Yang, ML | 1 |
| Hung, JH | 1 |
| Pfaffenrath, V | 2 |
| Rehm, M | 1 |
| Sancewicz-Pach, K | 1 |
| Chmiest, W | 1 |
| Lichota, E | 1 |
| Maalouf, EF | 1 |
| Battin, M | 1 |
| Counsell, SJ | 1 |
| Rutherford, MA | 1 |
| Manzur, AY | 1 |
| Egsieker, E | 1 |
| Mullins, ME | 1 |
| Naunheim, R | 1 |
| Sheehan, JE | 1 |
| Mitchell, AA | 1 |
| Silverman, JJ | 1 |
| Carithers, RL | 1 |
| Levy, G | 1 |
| Garrettson, LK | 1 |
| Soda, DM | 1 |
| McElhatton, PR | 1 |
| Sullivan, FM | 1 |
| Volans, GN | 1 |
| Fitzpatrick, R | 1 |
| Munro, CD | 1 |
| Kumar, A | 1 |
| Rae, MD | 1 |
| Riggs, BS | 1 |
| Bronstein, AC | 1 |
| Kulig, K | 1 |
| Archer, PG | 1 |
| Rumack, BH | 1 |
| Katz, VL | 1 |
| Peterson, R | 1 |
| Cefalo, RC | 1 |
| Howden, CW | 1 |
| Ludmir, J | 1 |
| Main, DM | 1 |
| Landon, MB | 1 |
| Robertson, RG | 1 |
| Van Cleave, BL | 1 |
| Collins, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study[NCT06025890] | 2,100 participants (Anticipated) | Interventional | 2022-12-07 | Recruiting | |||
| The National Standard for Normal Fetal Growth[NCT00912132] | 2,802 participants (Actual) | Observational | 2009-05-19 | Completed | |||
| The Efficacy of Transcutaneous Electrical Nerve Stimulation Versus Local Anaesthetic Cream in Alleviating the Pain of Local Anaesthetic Injections in Adults - A Randomised Controlled Trial[NCT03992820] | 8 participants (Actual) | Interventional | 2019-07-01 | Terminated (stopped due to Stopped early due to COVID19 restrictions) | |||
| Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants[NCT01755728] | Phase 3 | 19 participants (Actual) | Interventional | 2013-01-01 | Completed | ||
| Do Preoperative Carbohydrate Drinks Prevent Preoperative Catabolism in Mothers Undergoing Elective Caesarean Section? A Randomised Controlled Study[NCT03220997] | 200 participants (Anticipated) | Interventional | 2017-08-31 | Not yet recruiting | |||
| A Phase 2a Study to Evaluate the Safety and Tolerability of OCR-002 (Ornithine Phenylacetate) in the Treatment of Patients With Acute Liver Failure/Severe Acute Liver Injury[NCT01548690] | Phase 2 | 47 participants (Actual) | Interventional | 2012-06-30 | Completed | ||
| Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To evaluate the effect of OCR-002 on ammonia levels in patients with acute liver failure/severe acute liver injury (NCT01548690)
Timeframe: Baseline and 72 Hours
| Intervention | Percent Change (Mean) |
|---|---|
| Maximum Dose Level 3.33 g/24h | 41.2 |
| Maximum Dose Level 6.65 g/24h | 16.6 |
| Maximum Dose Level 10 g/24h | 41.8 |
| Maximum Dose Level 20g/24h | 38.4 |
To evaluate the steady state pharmacokinetic and pharmacodynamic profile of OCR-002 in patients with impaired and intact renal function using urinary phenylacetylglutamine (PAGN) as a surrogate marker (NCT01548690)
Timeframe: 24 Hours after last infusion
| Intervention | micrograms per millileter (Mean) |
|---|---|
| Maximum Dose Level 3.33 g/24h | 65.6 |
| Maximum Dose Level 6.65 g/24h | 32.2 |
| Maximum Dose Level 10 g/24h | 33.4 |
| Maximum Dose Level 20g/24h | 104.9 |
The orientation log focuses on orientation to place, time, and circumstance. There are 10 items on the orientation log, which are scored 0-3. A spontaneous correct response is awarded 3 points. A spontaneous response that is lacking or incorrect, but a correct response is provided following a logical cue is awarded 2 points. A score of 1 is given if spontaneous and cued responses are lacking or incorrect, but a correct response is provided in a recognition format. A score of 0 is given if the spontaneous, cued, or recognition format does not generate a correct answer. Scores from the 10 items are summed and the final score ranges from 0 to 30. (NCT01548690)
Timeframe: 30 Days
| Intervention | units on a scale (Mean) |
|---|---|
| Maximum Dose Level 3.33 g/24h | 23.8 |
| Maximum Dose Level 6.65 g/24h | 24.0 |
| Maximum Dose Level 10 g/24h | 24.0 |
| Maximum Dose Level 20g/24h | 24.0 |
The West Haven Criteria (WHC) for Hepatic Encephalopathy measures the severity of encephalopathy and patient's level of consciousness. The scale ranges from 0 to 4; a minimum score of 0 represents a better outcome, and a maximum total score of 4 represents a worse outcome. A score of 0 corresponds to normal consciousness and behavior and normal neurological examination. A score of 1 corresponds to mild lack of awareness, shortened attention span, and impaired addition or subtraction; mild asterixis or tremor. A score of 2 corresponds to lethargy, disorientated or inappropriate behavior, obvious asterixis; slurred speech. A score of 3 corresponds to somnolent but arousable, gross disorientation or bizarre behavior, muscle rigidity and clonus; hyperreflexia. A score of 4 corresponds to coma and decerebrate posturing. (NCT01548690)
Timeframe: 120 hours from start of infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Maximum Dose Level 3.33 g/24h | 2.4 |
| Maximum Dose Level 6.65 g/24h | 3.2 |
| Maximum Dose Level 10 g/24h | 1.6 |
| Maximum Dose Level 20g/24h | 1.8 |
To evaluate the safety and tolerability of OCR-002 in patients with acute liver failure/severe acute liver injury (NCT01548690)
Timeframe: 30 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Maximum Dose Level 3.33 g/24h | 0 |
| Maximum Dose Level 6.65 g/24h | 0 |
| Maximum Dose Level 10 g/24h | 0 |
| Maximum Dose Level 20g/24h | 0 |
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 189 |
| Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1078 |
| Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 78 |
| Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 303 |
| Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 134 |
| Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 141 |
| Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 42 |
| Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 352 |
| Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 264 |
| Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 668 |
| Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1506 |
| Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 214 |
| Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 26 |
| Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 54 |
| Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 9 |
| Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 23 |
| Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 290 |
| Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 8 |
| Placebo Arm | 21 |
23 reviews available for acetaminophen and Complications, Pregnancy
| Article | Year |
|---|---|
Environmental risk factors, protective factors, and peripheral biomarkers for ADHD: an umbrella review.
Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Biomarkers; Female; Humans; Pre-Eclamp | 2020 |
Opioid Use and Misuse in Pregnancy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory A | 2020 |
Non-prescribed drug use and predictors among pregnant women in Ethiopia: systematic review and meta-analysis.
Topics: Acetaminophen; Ethiopia; Female; Humans; Mothers; Pregnancy; Pregnancy Complications; Pregnant Women | 2022 |
[Pharmacological Basis of Pain Treatment].
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Dipy | 2018 |
Medications that Cause Fetal Anomalies and Possible Prevention Strategies.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Analg | 2019 |
Medication Use and Pain Management in Pregnancy: A Critical Review.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug | 2019 |
Acetaminophen and pregnancy: short- and long-term consequences for mother and child.
Topics: Acetaminophen; Antipyretics; Child; Female; Fetal Development; Fetus; Humans; Liver; Maternal Exposu | 2013 |
New problems arising from old drugs: second-generation effects of acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Asthma; Chemical and Drug Induced Liver Injury; Ch | 2014 |
Over-the-counter medications: Risk and safety in pregnancy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Dose-Response Relationship, Drug; Femal | 2015 |
Liver Failure in Pregnancy.
Topics: Abortion, Therapeutic; Acetaminophen; Critical Care; Drug Overdose; Fatty Liver; Female; HELLP Syndr | 2016 |
Ongoing Pharmacological Management of Chronic Pain in Pregnancy.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chr | 2016 |
[Analgesic drugs during pregnancy].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa | 2016 |
Management of RA medications in pregnant patients.
Topics: Abatacept; Acetaminophen; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoc | 2009 |
Prenatal tolerability of acetaminophen and other over-the-counter non-selective cyclooxygenase inhibitors.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Analgesics, Non-Narcotic; Animals; Cyclooxygenase Inhibi | 2012 |
[Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acupuncture Points; Acupuncture Therapy; Adult; Analgesi | 2003 |
[Drug therapy in pregnancy--a practical guide].
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Bacte | 2004 |
Acetaminophen overdose in pregnancy.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Dru | 2005 |
Etiologies of acute liver failure.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Budd-Chiari Syndrome; Drug-Related Side Effects and Adverse | 2008 |
Drug therapy in autoimmune diseases.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Autoimmune Diseases; Azathiopri | 1983 |
Analgesics during pregnancy.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Birth Weight; Female; Fetal Death; | 1983 |
[Amidazophen. Yes or no?].
Topics: Acetaminophen; Adult; Aminopyrine; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal | 1995 |
Migraine in pregnancy: what are the safest treatment options?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Female; Humans; Migraine Disorders; Pregnancy; Pre | 1998 |
Paracetamol poisoning in pregnancy: an analysis of the outcomes of cases referred to the Teratology Information Service of the National Poisons Information Service.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Female; Follow-Up Studies; Humans; Infant, Newborn; Info | 1990 |
8 trials available for acetaminophen and Complications, Pregnancy
| Article | Year |
|---|---|
Do exercises improve back pain in pregnancy?
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Back Pain; Chemotherapy, Adjuvant; Exercise Therapy; F | 2017 |
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study).
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Codeine; Diphenhydramine; Double-Blind Method; Drug A | 2018 |
Intracutaneous sterile water injection versus oral paracetamol for renal colic during pregnancy: a randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; Humans; Injections; Pregnancy; Pregnancy Com | 2013 |
Transcutaneous electrical nerve stimulation improves low back pain during pregnancy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Exercise Therapy; Female; Humans; Low Back Pain; Pai | 2012 |
Acupuncture for low back pain in pregnancy--a prospective, quasi-randomised, controlled study.
Topics: Acetaminophen; Acupuncture Therapy; Adult; Analgesics, Non-Narcotic; Female; Humans; Low Back Pain; | 2004 |
Gastric emptying of water in obese pregnant women at term.
Topics: Acetaminophen; Adult; Anesthesia, Obstetrical; Body Mass Index; Cesarean Section; Cross-Over Studies | 2007 |
The adverse influence of pregnancy upon sulphation: a clue to the pathogenesis of intrahepatic cholestasis of pregnancy?
Topics: Acetaminophen; Adult; Arylsulfotransferase; Blood Platelets; Cholestasis; Contraceptives, Oral; Estr | 1994 |
[The treatment of postoperative pain in obstetrical-gynecologic surgery. A comparative study between ST-679 and paracetamol].
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroida | 1993 |
62 other studies available for acetaminophen and Complications, Pregnancy
| Article | Year |
|---|---|
Prenatal paracetamol exposure and neurodevelopmental outcomes in preschool-aged children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child Behavior; Child Behavior Disorders; Child Development | 2020 |
Associations between paracetamol (acetaminophen) intake between 18 and 32 weeks gestation and neurocognitive outcomes in the child: A longitudinal cohort study.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorder | 2020 |
Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorder | 2020 |
Maternal acetaminophen use during pregnancy and childhood behavioural problems: Discrepancies between mother- and teacher-reported outcomes.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorders; Chi | 2020 |
Acetaminophen use in pregnancy: Examining prevalence, timing, and indication of use in a prospective birth cohort.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Arthritis; Behavioral Symptoms; Cohort Studies; Dose | 2020 |
Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Brazil; Child Behavior; Child Development; Child, Preschool | 2020 |
Low neurodevelopmental performance and behavioural/emotional problems at 24 and 48 months in Brazilian children exposed to acetaminophen during foetal development.
Topics: Acetaminophen; Affective Symptoms; Analgesics, Non-Narcotic; Brazil; Child Behavior; Child Developme | 2020 |
Malnourishment-Associated Acetaminophen Toxicity in Pregnancy.
Topics: Acetaminophen; Acidosis; Adult; Diagnosis, Differential; Female; Humans; Malnutrition; Poisoning; Pr | 2021 |
Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Cohort Studies; Drug Substitution; Drug | 2017 |
Managing migraine in pregnancy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Antiemetics; Female; Humans; Migraine with Aura; Pre | 2018 |
Intravenous acetaminophen for the treatment of intrapartum fever and resolution of fetal tachycardia: a novel use for an old medication.
Topics: Acetaminophen; Antipyretics; Female; Fetal Diseases; Fever; Humans; Infant, Newborn; Infusions, Intr | 2017 |
Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study.
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Diphenhydramine; Drug Therapy, Combination; Female; H | 2019 |
Comparison of fetal growth by maternal prenatal acetaminophen use.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biometry; Body Mass Index; Female; Fe | 2019 |
Outcomes of liver transplantation for acute fatty liver disease of pregnancy.
Topics: Acetaminophen; Adolescent; Adult; Case-Control Studies; Fatty Liver; Female; Follow-Up Studies; Graf | 2019 |
Clinical inquiry. How can pregnant women safely relieve low-back pain?
Topics: Acetaminophen; Evidence-Based Medicine; Female; Humans; Low Back Pain; Physical Therapy Modalities; | 2013 |
Re: Intracutaneous sterile water injection versus oral paracetamol for renal colic during pregnancy: a randomized controlled trial. Int Urol Nephrol 2013; 45:321–325, DOI 10.1007/s11255-013-0405-3.
Topics: Acetaminophen; Female; Humans; Pregnancy; Pregnancy Complications; Renal Colic; Water | 2014 |
Response to the letter by Sharma et al.: Intracutaneous sterile water injection versus oral paracetamol for renal colic during pregnancy: a randomized controlled trial. Int Urol Nephrol 2013; 45:321-325, DOI 10.1007/s11255-013-0405-3.
Topics: Acetaminophen; Female; Humans; Pregnancy; Pregnancy Complications; Renal Colic; Water | 2014 |
Marked variability in peri-partum anesthetic management of patients on buprenorphine maintenance therapy (BMT): can there be an underlying acute opioid induced hyperalgesia precipitated by neuraxial opioids in BMT patients?
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Buprenorphine; Cesarea | 2013 |
Kikuchi-Fujimoto disease: an unusual cause of neck swelling in pregnancy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Biopsy, Fine-Needle; Diagnosi | 2015 |
Pregnancy and lactation period: Which local anesthetics and analgesics?
Topics: Abnormalities, Drug-Induced; Acetaminophen; Analgesics; Anesthetics, Local; Breast Feeding; Carticai | 2016 |
Association of Acetaminophen Use During Pregnancy With Behavioral Problems in Childhood: Evidence Against Confounding.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Attention Deficit Disorder with Hyperactivity; Child; Child | 2016 |
Medication utilization pattern for management of pregnancy complications: a study in Western Nepal.
Topics: Acetaminophen; Adult; Anti-Infective Agents; Butylscopolammonium Bromide; Cross-Sectional Studies; D | 2016 |
Prenatal acetaminophen use and outcomes in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Fever; Humans; Neurodevelo | 2017 |
Acute liver failure in Lithuania.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Bilirubin; Chemical and Drug Induced Liver Injury; Co | 2008 |
Is the effect of prenatal paracetamol exposure on wheezing in preschool children modified by asthma in the mother?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Asthma; Child, Preschool; Female; Humans; Male; Mothers; Pr | 2009 |
Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury.
Topics: Acetaminophen; Adrenal Cortex Hormones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Ste | 2010 |
[Acute paracetamol overdose during pregnancy: a case report].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cesarean Section; Chemical and Drug Induced Liver In | 2011 |
[Drugs in pregnancy: study in the EFEMERIS database (2004 to 2008)].
Topics: Acetaminophen; Databases, Factual; Drug Prescriptions; Female; Folic Acid; Humans; Immune Sera; Immu | 2011 |
Management of a parturient with mast cell activation syndrome.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthesia, Epidural; | 2013 |
Maternal drug use during pregnancy and asthma risk among children.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Child; Child | 2013 |
Acute fatty liver of pregnancy and acetaminophen toxicity leading to liver failure and postpartum liver transplantation. A case report.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Diagnos | 2002 |
Paracetamol use in pregnancy and wheezing in early childhood.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Asthma; Eczema; Female; Humans; Infant; Longitudin | 2002 |
[Upper and lower neural tube defects: prevalence and association with illnesses and drugs].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anencephaly; Case-Control Studies; Confidence Intervals; Co | 2002 |
AROMATIC DRUGS AND CONGENITAL CATARACTS.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acetazolamide; Anti-Bacterial Agents; Cardiovascular Age | 1964 |
Gastroschisis and pseudoephedrine during pregnancy.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenergic Agents; Case-Control Studies; Ephedrine; Fema | 2004 |
Liver transplant and obstetrics.
Topics: Acetaminophen; Adult; Congenital Abnormalities; Drug Overdose; Female; Hepatolenticular Degeneration | 2004 |
Short-term paracetamol therapy during pregnancy and a lower rate of preterm birth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Infective Agents; Chronic | 2005 |
Patient's page. Bone health facts.
Topics: Acetaminophen; Adult; Child; Child Abuse; Chronic Disease; Female; Humans; Male; Pain; Pain Manageme | 2005 |
Dipyrone-induced oligohydramnios and ductus arteriosus restriction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non | 2006 |
Beta 2-microglobulin and other proteins as parameter for tubular function.
Topics: Acetaminophen; Amino Acid Sequence; Aspirin; beta 2-Microglobulin; Beta-Globulins; Female; Graft Rej | 1981 |
ABC of poisoning: paracetamol.
Topics: Acetaminophen; Female; Fetus; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy; Pre | 1984 |
Prune perineum syndrome: report of a second case.
Topics: Abnormalities, Multiple; Acetaminophen; Adult; Codeine; Dextropropoxyphene; Dicyclomine; Female; Hum | 1983 |
Paracetamol overdose in the second trimester of pregnancy. Case report.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Female; Fetal Blood; Humans; Infant, Newborn; Male; Pregn | 1984 |
Acetaminophen overdose in the third trimester of pregnancy.
Topics: Acetaminophen; Adult; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; Pregnancy; Pregnancy Co | 1982 |
Risk factors for a first febrile seizure: a matched case-control study.
Topics: Acetaminophen; Acute Disease; Case-Control Studies; Comorbidity; Female; Fever; Gastroenteritis; Hum | 1995 |
Auxiliary partial orthotopic liver transplantation for acute liver failure: the Hannover experience.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Child; Female; Germany; Hepatitis A; Humans; Liver | 1994 |
Neonatal abstinence syndrome due to codeine.
Topics: Acetaminophen; Adult; Codeine; Female; Humans; Infant, Newborn; Male; Neonatal Abstinence Syndrome; | 1997 |
Acetaminophen poisoning in late pregnancy. A case report.
Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Blood Gas Analysis; Fatal Outcome; F | 1997 |
Suicidal paracetamol poisoning of a pregnant woman just before a delivery.
Topics: Acetaminophen; Adult; Aspartate Aminotransferases; Drug Overdose; Female; Humans; Infant, Newborn; I | 1999 |
Arthrogryposis multiplex congenita and bilateral mid-brain infarction following maternal overdose of co-proxamol.
Topics: Acetaminophen; Arthrogryposis; Brain; Brain Damage, Chronic; Cocaine-Related Disorders; Dextropropox | 1997 |
[Migraine therapy in pregnancy. Paracetamol leads in acute therapy].
Topics: Acetaminophen; Analgesics; Combined Modality Therapy; Female; Humans; Infant, Newborn; Migraine Diso | 1999 |
Tremor after ingestion of Tazist-D and Tylenol 3.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Clemastine; Female; Histamine H1 Antagonists; Humans | 2000 |
Maternal medication use and risks of gastroschisis and small intestinal atresia.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Aspirin; Canada; Ephedrine; Fema | 2002 |
Acetaminophen overdose.
Topics: Acetaminophen; Adult; Biotransformation; Chemical and Drug Induced Liver Injury; Female; Humans; Pre | 1978 |
Letter: Evidence of placental transfer of acetaminophen.
Topics: Acetaminophen; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Compli | 1975 |
Women to have more say in births?
Topics: Acetaminophen; Aspirin; Codeine; Female; Humans; Pain; Pregnancy; Pregnancy Complications | 1990 |
Paracetamol overdose in children.
Topics: Acetaminophen; Adolescent; Child; Child, Preschool; Drug Overdose; Female; Humans; Incidence; Infant | 1990 |
Acute acetaminophen overdose during pregnancy.
Topics: Abortion, Spontaneous; Acetaminophen; Acetylcysteine; Acute Disease; Adult; Female; Fetal Death; Hum | 1989 |
Pseudotumor cerebri and pregnancy.
Topics: Acetaminophen; Acetazolamide; Codeine; Female; Furosemide; Humans; Infant, Newborn; Male; Pregnancy; | 1989 |
Treatment of common minor ailments.
Topics: Acetaminophen; Antacids; Antiemetics; Aspirin; Dyspepsia; Female; Heartburn; Histamine H1 Antagonist | 1986 |
Maternal acetaminophen overdose at 15 weeks of gestation.
Topics: Acetaminophen; Acetylcysteine; Adult; Female; Fetus; Humans; Liver; Necrosis; Pregnancy; Pregnancy C | 1986 |
Acetaminophen overdose in the second trimester of pregnancy.
Topics: Acetaminophen; Acetylcysteine; Adult; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy | 1986 |