Page last updated: 2024-10-22

acetaminophen and Complications, Labor

acetaminophen has been researched along with Complications, Labor in 8 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Acetaminophen prophylaxis prevented neither maternal hyperthermia nor fever secondary to epidural analgesia, suggesting that the mechanism underlying fever does not include centrally mediated perturbations of maternal thermoregulation."9.11Prophylactic acetaminophen does not prevent epidural fever in nulliparous women: a double-blind placebo-controlled trial. ( Citron, DR; Evans, T; Goetzl, L; Lieberman, E; Richardson, BE; Rivers, J; Suresh, MS, 2004)
"Salicylates have been the most widely studied of the nonnarcotic analgesics in pregnancy, and in the last 20 years evidence has accumulated indicating that their ingestion in pregnancy may have adverse effects on the mother and her child."8.76Maternal and fetal effects of acetaminophen and salicylates in pregnancy. ( Collins, E, 1981)
"Acetaminophen prophylaxis prevented neither maternal hyperthermia nor fever secondary to epidural analgesia, suggesting that the mechanism underlying fever does not include centrally mediated perturbations of maternal thermoregulation."5.11Prophylactic acetaminophen does not prevent epidural fever in nulliparous women: a double-blind placebo-controlled trial. ( Citron, DR; Evans, T; Goetzl, L; Lieberman, E; Richardson, BE; Rivers, J; Suresh, MS, 2004)
"Salicylates have been the most widely studied of the nonnarcotic analgesics in pregnancy, and in the last 20 years evidence has accumulated indicating that their ingestion in pregnancy may have adverse effects on the mother and her child."4.76Maternal and fetal effects of acetaminophen and salicylates in pregnancy. ( Collins, E, 1981)
" We defined exposure to NSAIDs as at least two records of NSAID prescriptions during early pregnancy (first 90 days of pregnancy for congenital malformations and first 19 weeks for nonmalformation outcomes) and compared against three distinct referent groups of (1) unexposed, no NSAID prescription during the 3 months before pregnancy start to end of early pregnancy; (2) acetaminophen-exposed, at least two acetaminophen prescriptions during early pregnancy (i."4.31Neonatal and maternal adverse outcomes and exposure to nonsteroidal anti-inflammatory drugs during early pregnancy in South Korea: A nationwide cohort study. ( Choe, SA; Choi, A; Choi, EY; Han, JY; Jeong, HE; Noh, Y; Shin, JY; Sung, JH; Yon, DK, 2023)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Choi, EY1
Jeong, HE1
Noh, Y1
Choi, A1
Yon, DK1
Han, JY1
Sung, JH1
Choe, SA1
Shin, JY1
Morrison, CL1
Glenn, LL1
Lavesson, T2
Källén, K2
Olofsson, P2
Åkerman, F1
Goetzl, L1
Rivers, J1
Evans, T1
Citron, DR1
Richardson, BE1
Lieberman, E1
Suresh, MS1
Reilly, DR1
Oppenheimer, LW1
Collins, E1
Sharley, CB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Double-Blind, Placebo-Controlled Study of Effects of Combined Spinal Epidural Analgesia on Intrapartum Fever.[NCT00802646]0 participants (Actual)Interventional2009-06-30Withdrawn (stopped due to study moved to alternate site)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetaminophen and Complications, Labor

ArticleYear
Maternal and fetal effects of acetaminophen and salicylates in pregnancy.
    Obstetrics and gynecology, 1981, Volume: 58, Issue:5 Suppl

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Birth Weight; Chemical and Drug Induced Liver I

1981

Trials

1 trial available for acetaminophen and Complications, Labor

ArticleYear
Prophylactic acetaminophen does not prevent epidural fever in nulliparous women: a double-blind placebo-controlled trial.
    Journal of perinatology : official journal of the California Perinatal Association, 2004, Volume: 24, Issue:8

    Topics: Acetaminophen; Adult; Anesthesia, Epidural; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Me

2004

Other Studies

6 other studies available for acetaminophen and Complications, Labor

ArticleYear
Neonatal and maternal adverse outcomes and exposure to nonsteroidal anti-inflammatory drugs during early pregnancy in South Korea: A nationwide cohort study.
    PLoS medicine, 2023, Volume: 20, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Female; Hemorrhage; Humans;

2023
Statistical significance of paracetamol administration in fetal and maternal body temperatures.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 171, Issue:1

    Topics: Acetaminophen; Antipyretics; Body Temperature; Female; Fever; Humans; Obstetric Labor Complications;

2013
Authors' response.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 171, Issue:1

    Topics: Acetaminophen; Antipyretics; Body Temperature; Female; Fever; Humans; Obstetric Labor Complications;

2013
Effects on fetal and maternal temperatures of paracetamol administration during labour: a case-control study.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 168, Issue:2

    Topics: Acetaminophen; Adult; Algorithms; Antipyretics; Axilla; Body Temperature; Case-Control Studies; Coho

2013
Fever in term labour.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2005, Volume: 27, Issue:3

    Topics: Acetaminophen; Amniotic Fluid; Analgesia, Epidural; Female; Fever; Humans; Intensive Care, Neonatal;

2005
The value of physiotherapy in obstetrics.
    The Medical journal of Australia, 1970, Jun-06, Volume: 1, Issue:23

    Topics: Acetaminophen; Anesthesia, Obstetrical; Anesthetics, Local; Aspirin; Codeine; Conditioning, Psycholo

1970