acetaminophen has been researched along with Cognition Disorders in 11 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trazodone 100 mg may cause cognitive driving impairment." | 2.78 | The effect of trazodone on standardized field sobriety tests. ( Barnett, MJ; Bui, QV; Ip, EJ; Kazani, A; Perry, PJ; Serino, MJ; Wright, R, 2013) |
| "Colitis was induced in rats by an enema containing 2,4,6-trinitrobenzen sulfonic acid." | 1.32 | Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats. ( Ardid, D; Eschalier, A; Etienne, M; Jourdan, D; Millecamps, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tung, EE | 1 |
| Litin, SC | 1 |
| Bundrick, JB | 1 |
| Ip, EJ | 1 |
| Bui, QV | 1 |
| Barnett, MJ | 1 |
| Kazani, A | 1 |
| Wright, R | 1 |
| Serino, MJ | 1 |
| Perry, PJ | 1 |
| Viberg, H | 1 |
| Eriksson, P | 1 |
| Gordh, T | 1 |
| Fredriksson, A | 1 |
| Levenson, D | 1 |
| Kang, JH | 1 |
| Grodstein, F | 1 |
| Millecamps, M | 1 |
| Etienne, M | 1 |
| Jourdan, D | 1 |
| Eschalier, A | 1 |
| Ardid, D | 1 |
| Nygaard, HA | 1 |
| Jarland, M | 1 |
| Chibnall, JT | 1 |
| Tait, RC | 1 |
| Harman, B | 1 |
| Luebbert, RA | 1 |
| Fernandez, A | 1 |
| Schmidt, JM | 1 |
| Claassen, J | 1 |
| Pavlicova, M | 1 |
| Huddleston, D | 1 |
| Kreiter, KT | 1 |
| Ostapkovich, ND | 1 |
| Kowalski, RG | 1 |
| Parra, A | 1 |
| Connolly, ES | 1 |
| Mayer, SA | 1 |
| Sporer, KA | 1 |
| Khayam-Bashi, H | 1 |
| Feldt, KS | 1 |
| Ryden, MB | 1 |
| Miles, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Bromocriptine to Reduce Body Temperature in Febrile Critically-ill Adults With Acute Neurologic Disease: an Open-label, Blinded Endpoint, Randomized Controlled Trial[NCT03496545] | Phase 1/Phase 2 | 47 participants (Actual) | Interventional | 2018-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Mean total body temperature burden above 37°C over 48 hours during which patient receives either control or intervention medication. (NCT03496545)
Timeframe: over 48 hours
| Intervention | Temperature in degrees Celsius (Mean) |
|---|---|
| Acetaminophen | 37.8 |
| Bromocriptine and Acetaminophen | 37.7 |
Time in minutes where the temperature is ≥ 38.3ºC during the 48 hours of control versus intervention administration. (NCT03496545)
Timeframe: 48 hours
| Intervention | Minutes (Mean) |
|---|---|
| Acetaminophen | 216 |
| Bromocriptine and Acetaminophen | 300 |
Time in minutes it took after medication administration for the temperature to reach < 37.5ºC. (NCT03496545)
Timeframe: 48 hours
| Intervention | Minutes (Mean) |
|---|---|
| Acetaminophen | 253.5 |
| Bromocriptine and Acetaminophen | 556 |
Episodes of symptomatic hypotension, including decrease in supine systolic and diastolic pressures of greater than 20mm and 10mm Hg respectively with patient reported accompanying symptoms of light headedness or dizziness and incidence of nausea and headache. (NCT03496545)
Timeframe: Nursing assessment at every shift during 48 hour study period after first drug administration
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Decrease in blood pressure | Nausea | Headache | |
| Acetaminophen | 12 | 2 | 8 |
| Bromocriptine and Acetaminophen | 17 | 3 | 12 |
2 trials available for acetaminophen and Cognition Disorders
| Article | Year |
|---|---|
The effect of trazodone on standardized field sobriety tests.
Topics: Acetaminophen; Adult; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Psychomotor Pe | 2013 |
Effect of acetaminophen on behavior, well-being, and psychotropic medication use in nursing home residents with moderate-to-severe dementia.
Topics: Acetaminophen; Activities of Daily Living; Affective Symptoms; Aged; Aged, 80 and over; Alzheimer Di | 2005 |
9 other studies available for acetaminophen and Cognition Disorders
| Article | Year |
|---|---|
Clinical Pearls in Geriatrics.
Topics: Acetaminophen; Aged; Aged, 80 and over; Automobile Driving; Cognition Disorders; Cognitive Dysfuncti | 2017 |
Paracetamol (acetaminophen) administration during neonatal brain development affects cognitive function and alters its analgesic and anxiolytic response in adult male mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain | 2014 |
Guidelines on pain control in seniors favor certain NSAIDs and strategies for the cognitively impaired.
Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cognition Disorders; Human | 2002 |
Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging women.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2003 |
Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Attention; Behavior, Animal; | 2004 |
Are nursing home patients with dementia diagnosis at increased risk for inadequate pain treatment?
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Cognition Disorders; C | 2005 |
Fever after subarachnoid hemorrhage: risk factors and impact on outcome.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Body Temperature; Brain; Cerebral Hemorrhage; Cognition Dis | 2007 |
Acetaminophen and salicylate serum levels in patients with suicidal ingestion or altered mental status.
Topics: Acetaminophen; Acid-Base Equilibrium; Adult; Aged; Analgesics, Non-Narcotic; Cognition Disorders; Dr | 1996 |
Treatment of pain in cognitively impaired compared with cognitively intact older patients with hip-fracture.
Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; C | 1998 |