Page last updated: 2024-10-22

acetaminophen and Cirrhoses, Experimental Liver

acetaminophen has been researched along with Cirrhoses, Experimental Liver in 8 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
" After acetaminophen intoxication, necrosis was significantly increased in TAFI-/- mice at 24 hours (h) after injection."3.79TAFI deficiency promotes liver damage in murine models of liver failure through defective down-regulation of hepatic inflammation. ( Adelmeijer, J; Hugenholtz, GC; Lisman, T; Meijers, JC; Porte, RJ, 2013)
"The mechanism(s) of liver damage initiated by ingestion of toxic components of thermally oxidized lipids was compared in a rat model with the documented mechanisms of hepatic failure and necrosis initiated by acetaminophen."3.69Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis. ( Fouad, FM; Mamer, OA; Shahidi, F, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Karpińska, G1
Dobrowolski, JC1
Yinda, CK1
Rector, A1
Zeller, M1
Conceição-Neto, N1
Heylen, E1
Maes, P1
Ghogomu, SM1
Van Ranst, M1
Matthijnssens, J1
Arthanari, SK1
Vanitha, J1
Ganesh, M1
Venkateshwaran, K1
de Lama Caro-Patón, G1
García-Salido, A1
Iglesias-Bouzas, MI1
Guillén, M1
Cañedo-Villaroya, E1
Martínez-Romera, I1
Serrano-González, A1
Casado-Flores, J1
Gale, P2
Chen, X2
Li, H1
Lucero-Prisno, DE1
Abdullah, AS1
Huang, J1
Laurence, C1
Liang, X1
Ma, Z1
Mao, Z1
Ren, R1
Wu, S1
Wang, N1
Wang, P2
Wang, T1
Yan, H1
Zou, Y1
Olsen, KM1
Gabler, NK1
Rademacher, CJ1
Schwartz, KJ1
Schweer, WP1
Gourley, GG1
Patience, JF1
Rauch, JC1
Stokes, RS1
Shike, DW1
Luebbe, KM1
Stalker, LA1
Klopfenstein, TJ1
Funston, RN1
Unger, PA1
Lighaam, LC1
Vermeulen, E1
Kruithof, S1
Makuch, M1
Culver, EL1
van Bruggen, R1
Remmerswaal, EBM1
Ten Berge, IJM1
Emmens, RW1
Niessen, HWM1
Barnes, E1
Wolbink, GJ1
van Ham, SM1
Rispens, T1
Liang, JX1
Lin, J1
Liu, J1
Wang, X1
Zhang, T1
Li, J1
Wu, Y2
Venier, M1
Salamova, A1
Gonçales, VR1
Lian, J1
Gautam, S1
Tilley, RD1
Gooding, JJ1
Kandel, YR1
Bradley, CA1
Chilvers, MI1
Mathew, FM1
Tenuta, AU1
Smith, DL1
Wise, KA1
Mueller, DS1
Lu, N1
Lu, M1
Liu, P1
Xu, H1
Qiu, X1
Hu, S1
Bai, S1
Wu, J1
Xue, S1
Dai, X1
Dharmage, SC1
Abramson, MJ1
Erbas, B1
Bennett, CM1
Svanes, C1
Hui, J1
Axelrad, C1
Lowe, AJ1
Lodge, CJ1
Hoshi, M1
Osawa, Y1
Nakamoto, K1
Morita, N1
Yamamoto, Y1
Ando, T1
Tashita, C1
Nabeshima, T1
Saito, K1
Gianesello, L1
Del Prete, D1
Ceol, M1
Priante, G1
Calò, LA1
Anglani, F1
Vekaria, HJ1
Hubbard, WB1
Scholpa, NE1
Spry, ML1
Gooch, JL1
Prince, SJ1
Schnellmann, RG1
Sullivan, PG1
Zhang, Q1
Hu, R1
Gu, Z1
Zhang, M1
Zhang, Z1
Peng, Y1
Feng, L1
Li, X3
Zhao, C1
Sarfaraz, K1
Gao, L1
Wang, H1
Wan, C1
Leng, J1
Yang, P1
Gao, X1
Gao, J1
Emam, HE1
Saad, NM1
Abdallah, AEM1
Ahmed, HB1
Palombo, M1
Ianus, A1
Guerreri, M1
Nunes, D1
Alexander, DC1
Shemesh, N1
Zhang, H1
Xiong, Q1
Liu, YS1
Hu, LX1
Shi, ZQ1
Ying, GG1
Chen, R1
Hong, X1
Yan, S1
Zha, J1
Gu, H1
Zhong, Q1
Zeng, Y1
Zhang, S1
Bu, Y1
Farghali, M1
Mayumi, M1
Syo, K1
Satoshi, A1
Seiichi, Y1
Takashima, S1
Ono, H1
Ap, Y1
Yamashiro, T1
Ahmed, MM1
Kotb, S1
Iwasaki, M1
Ihara, I1
Umetsu, K1
Hu, B1
Wang, Y2
Quan, J1
Huang, K1
Gu, X1
Zhu, J1
Yan, Y1
Wu, P1
Yang, L1
Zhao, J1
Koók, L1
Nemestóthy, N1
Bélafi-Bakó, K1
Bakonyi, P1
Luo, X1
Zhang, F1
Li, Q1
Xia, Q1
Li, Z1
Ye, W1
Li, S1
Ge, C1
Zakkula, A1
Pulipati, S1
Dittakavi, S1
Bestha, RM1
Zainuddin, M1
Trivedi, RK1
Mullangi, R1
Lo, GH1
Lin, CW1
Tai, CM1
Perng, DS1
Chen, IL1
Yeh, JH1
Lin, HC1
Rocha, GS1
Silva, MKL1
Cesarino, I1
Hazzaa, SM1
Abdelaziz, SAM1
Abd Eldaim, MA1
Abdel-Daim, MM1
Elgarawany, GE1
Larsson, P1
Ljuslinder, I1
Öhlund, D1
Myte, R1
Löfgren-Burström, A1
Zingmark, C1
Ling, A1
Edin, S1
Palmqvist, R1
Murthi, P1
Rajaraman, G1
Erwich, JJHM1
Dimitriadis, E1
Yoon, HG1
Oh, D1
Ahn, YC1
Noh, JM1
Pyo, H1
Cho, WK1
Song, YM1
Park, M1
Hwang, NY1
Sun, JM1
Kim, HK1
Zo, JI1
Shim, YM1
Persano, A1
Quaranta, F1
Taurino, A1
Siciliano, PA1
Iannacci, J1
Malekbala, MR1
Soltani, S1
Abdul Rashid, S1
Abdullah, LC1
Rashid, U1
Nehdi, IA1
Choong, TSY1
Teo, SH1
Xu, P1
Yan, F1
Zhao, Y1
Sun, S1
Ying, L1
Quinzi, V1
Caruso, S1
Mummolo, S1
Nota, A1
Angelone, AM1
Mattei, A1
Gatto, R1
Marzo, G1
Xin, W1
Severino, J1
Venkert, A1
Yu, H1
Knorr, D1
Yang, JM1
Carlson, L1
Hicks, R1
De Rosa, I1
Beckmann, NA1
Bitsch, RG1
Schonhoff, M1
Siebenrock, KA1
Schwarze, M1
Jaeger, S1
Perugorria, MJ1
Esparza-Baquer, A1
Oakley, F2
Labiano, I1
Korosec, A1
Jais, A1
Mann, J2
Tiniakos, D1
Santos-Laso, A1
Arbelaiz, A1
Gawish, R1
Sampedro, A1
Fontanellas, A1
Hijona, E1
Jimenez-Agüero, R1
Esterbauer, H1
Stoiber, D1
Bujanda, L1
Banales, JM1
Knapp, S1
Sharif, O1
Mann, DA2
Abdel-Kawy, HS1
Moran-Salvador, E1
Garcia-Macia, M1
Sivaharan, A1
Sabater, L1
Zaki, MYW1
Knox, A1
Page, A1
Luli, S1
Hugenholtz, GC1
Meijers, JC1
Adelmeijer, J1
Porte, RJ1
Lisman, T1
Fouad, FM1
Shahidi, F1
Mamer, OA1
Manautou, JE1
Emeigh Hart, SG1
Khairallah, EA1
Cohen, SD1
Willson, RA1
Hart, FE1

Reviews

1 review available for acetaminophen and Cirrhoses, Experimental Liver

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013

Trials

1 trial available for acetaminophen and Cirrhoses, Experimental Liver

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013

Other Studies

7 other studies available for acetaminophen and Cirrhoses, Experimental Liver

ArticleYear
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.
    Gut, 2019, Volume: 68, Issue:3

    Topics: Acetaminophen; Aged; Animals; Carbon Tetrachloride; Case-Control Studies; Female; Hematopoietic Stem

2019
Effect of carvedilol versus propranolol on acute and chronic liver toxicity in rats.
    Drug and chemical toxicology, 2021, Volume: 44, Issue:1

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferas

2021
Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells.
    Gastroenterology, 2019, Volume: 157, Issue:5

    Topics: Acetaminophen; Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chemical and Drug

2019
TAFI deficiency promotes liver damage in murine models of liver failure through defective down-regulation of hepatic inflammation.
    Thrombosis and haemostasis, 2013, Volume: 109, Issue:5

    Topics: Acetaminophen; Actins; Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Ca

2013
Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis.
    Journal of toxicology and environmental health, 1995, Volume: 46, Issue:2

    Topics: Acetaminophen; Acute-Phase Reaction; Analysis of Variance; Animals; Benzoquinones; DNA; Drug Interac

1995
Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 29, Issue:2

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Clofibrate; Corn Oil; Cytoso

1996
Effect of experimental hepatic injury on in vitro drug-metabolizing enzyme activities in the rat.
    Gastroenterology, 1977, Volume: 73, Issue:4 Pt 1

    Topics: Acetaminophen; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Bilirubin; Cytochrome P-450

1977