Page last updated: 2024-10-22

acetaminophen and Chronic Kidney Failure

acetaminophen has been researched along with Chronic Kidney Failure in 72 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."7.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
" Limitations include retrospective review, selection bias, and absence of data on detail medications used, laboratory investigations and dosage of APAP intoxication."5.42Risk of Acute Kidney Injury and Long-Term Outcome in Patients With Acetaminophen Intoxication: A Nationwide Population-Based Retrospective Cohort Study. ( Chang, PY; Chen, JH; Chen, YG; Dai, MS; Huang, TC; Kao, CH; Lin, CL; Wu, YY, 2015)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."3.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
" There was no lysozymuria with severe uraemic heart failure, aspirin and paracetamol poisoning, or severe jaundice, nor in two cases of acute glomerulonephritis."3.65Lysozymuria and acute disorders of renal function. ( De Silva, KL; Harrison, JF; Parker, RW, 1973)
"Persons with advanced CKD and ESRD are at increased risk for adverse effects of analgesic agents because of enhanced drug sensitivity, comorbid conditions, and concurrent medication use."2.42Analgesia in patients with ESRD: a review of available evidence. ( Bennett, WM; Chertow, GM; Kurella, M, 2003)
" However, there is little evidence that chronic administration of APAP contributes to chronic renal disease and analgesic nephropathy."2.39Acetaminophen: acute and chronic effects on renal function. ( Blantz, RC, 1996)
"Aspirin may cause a transient shedding of renal tubular cells, alterations in urate excretion, inhibition of spironolactone action, and, in certain clinical settings, a reversible decline in renal function manifested as a fall in glomerular filtration that may be accompanied by mild water, sodium, and potassium retention."2.36Acute effects of aspirin and acetaminophen on renal function. ( Kimberly, RP; Plotz, PH, 1981)
" For 137 sessions, in 36 patients the total daily dosage of UV-absorbing drugs was less than 500 mg, and for 6 sessions 3 patients received additional UV-absorbing drugs."1.72Treatment with Paracetamol Can Interfere with the Intradialytic Optical Estimation in Spent Dialysate of Uric Acid but Not of Indoxyl Sulfate. ( Adoberg, A; Arund, J; Dhondt, A; Fridolin, I; Glorieux, G; Holmar, J; Lauri, K; Leis, L; Luman, M; Paats, J; Pilt, K; Tanner, R; Uhlin, F, 2022)
"Pain is a hallmark of this condition and can be extremely difficult to control."1.56Pain management in patients with end-stage renal disease and calciphylaxis- a survey of clinical practices among physicians. ( Chinnadurai, R; Lowney, AC; Miller, M; Sinha, S, 2020)
"We report here the successful treatment of hepatitis C virus (HCV) transmitted from a nucleic acid testing (NAT)-negative donor to three HCV-negative recipients-two renal transplants and one liver."1.46Successful treatment of donor-derived hepatitis C viral infection in three transplant recipients from a donor at increased risk for bloodborne pathogens. ( Cameron, A; Fenkel, JM; Frank, AM; Shah, AP; Singh, P, 2017)
" Limitations include retrospective review, selection bias, and absence of data on detail medications used, laboratory investigations and dosage of APAP intoxication."1.42Risk of Acute Kidney Injury and Long-Term Outcome in Patients With Acetaminophen Intoxication: A Nationwide Population-Based Retrospective Cohort Study. ( Chang, PY; Chen, JH; Chen, YG; Dai, MS; Huang, TC; Kao, CH; Lin, CL; Wu, YY, 2015)
" In conclusion, this study suggests that the increase of the bioavailability of propranolol in ESRD is partly induced by the inhibition of the hepatic metabolism of CYP1A2 by xanthine in the uremic serum."1.40Possibility of decrease in CYP1A2 function in patients with end-stage renal disease. ( Furukubo, T; Izumi, S; Minegaki, T; Nagatomo, M; Nishiguchi, K; Sugimoto, S; Tsujimoto, M; Yamakawa, T, 2014)
"Acetaminophen is a safe antipyretic and analgesic drug within the clinically recommended dosage range, but overdose can cause fatal liver and or kidney damage."1.38Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats. ( Arimizu, K; Chuang, VT; Hirata, S; Irie, T; Ishitsuka, Y; Kadowaki, D; Kitamura, K; Maruyama, T; Narita, Y; Otagiri, M; Sumikawa, S; Taguchi, K, 2012)
"Pain was much more prevalent among our CKD compared with non-CKD patients."1.36Pain prevalence in patients with chronic kidney disease. ( Dewar, K; Hashmi, S; Pham, PA; Pham, PC; Pham, PM; Pham, PT; Toscano, E, 2010)
" In contrast to acute renal insufficiency that may already occur after a single NSAID dose, analgesic nephropathy is a disease caused by long-term intake of NSAID compound analgesics and predominantly affects the middle and old age."1.33[Chronic interstitial nephritis in an 18-year-old due to intake of a compound analgesic]. ( Janssen, U; Jochum, E, 2006)
"Phenacetin was removed from the German market in 1986 and was replaced mainly in analgesic compounds by acetaminophen."1.30Incidence of analgesic nephropathy in Berlin since 1983. ( Preuschof, L; Schwarz, A; Zellner, D, 1999)
"We studied 716 patients treated for ESRD and 361 control subjects of similar age from Maryland, Virginia, West Virginia, and Washington, D."1.29Risk of kidney failure associated with the use of acetaminophen, aspirin, and nonsteroidal antiinflammatory drugs. ( Klag, MJ; Perneger, TV; Whelton, PK, 1994)
" It is not clear why regular dosing with paracetamol in haemodialysis patients did not cause the accumulation of paracetamol glucuronide or sulphate as predicted."1.29The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis. ( Martin, U; Prescott, LF; Temple, RM; Winney, RJ, 1993)
"The utility of saliva in patients with chronic renal failure is unclear."1.29Paracetamol and its metabolites in saliva and plasma in chronic dialysis patients. ( Khoo, YM; Lee, HS; Lye, WC; Tan, CC; Ti, TY, 1996)
" Due to many different pharmacokinetic properties, no perfect rules for dosage in acute or chronic hemodialysis exist."1.27Tranquilizers, analgetics and antidepressants in patients treated with hemodialysis. ( Forycki, Z; Ibe, K; Martens, F; Thalhofer, S, 1985)
" It is a process of limited capacity; the extent of sulfate conjugate formation and the metabolic clearance of drugs subject to conjugation with sulfate depend therefore on the dose, the dosage form, the route of administration, and the rate and duration of administration as well as on the pharmacokinetic parameters of competing processes."1.27Sulfate conjugation in drug metabolism: role of inorganic sulfate. ( Levy, G, 1986)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199024 (33.33)18.7374
1990's25 (34.72)18.2507
2000's11 (15.28)29.6817
2010's9 (12.50)24.3611
2020's3 (4.17)2.80

Authors

AuthorsStudies
Adoberg, A1
Paats, J1
Arund, J1
Dhondt, A1
Fridolin, I1
Glorieux, G1
Holmar, J1
Lauri, K1
Leis, L1
Luman, M1
Pilt, K1
Uhlin, F1
Tanner, R1
Moist, L1
Chinnadurai, R1
Sinha, S1
Lowney, AC1
Miller, M1
Davison, SN1
Tsujimoto, M1
Sugimoto, S1
Nagatomo, M1
Furukubo, T1
Izumi, S1
Yamakawa, T1
Minegaki, T1
Nishiguchi, K1
Chen, YG1
Lin, CL1
Dai, MS1
Chang, PY1
Chen, JH1
Huang, TC1
Wu, YY1
Kao, CH1
Dyer, C1
Shah, AP1
Cameron, A1
Singh, P1
Frank, AM1
Fenkel, JM1
Evans, M1
Fored, CM2
Bellocco, R1
Fitzmaurice, G1
Fryzek, JP2
McLaughlin, JK2
Nyrén, O2
Elinder, CG2
Pham, PC1
Dewar, K1
Hashmi, S1
Toscano, E1
Pham, PM1
Pham, PA1
Pham, PT1
Kuo, HW1
Tsai, SS1
Tiao, MM1
Liu, YC1
Lee, IM1
Yang, CY1
Kadowaki, D1
Sumikawa, S1
Arimizu, K1
Taguchi, K1
Kitamura, K1
Ishitsuka, Y1
Narita, Y1
Irie, T1
Chuang, VT1
Maruyama, T1
Otagiri, M1
Hirata, S1
Domagała, P1
Kwiatkowski, A1
Drozdowski, J1
Ostrowski, K1
Wszola, M1
Diuwe, P1
Durlik, M1
Paczek, L1
Chmura, A1
Martínez, JG1
Saus, C1
Morey, A1
Alarcón, A1
Kurella, M1
Bennett, WM1
Chertow, GM1
Bailie, GR1
Mason, NA1
Bragg-Gresham, JL1
Gillespie, BW1
Young, EW1
Jochum, E1
Janssen, U1
Michielsen, P3
Prescott, LF4
Seedat, YK1
MacSearraigh, ET1
Segasothy, M2
Tong, BK1
Kamal, A1
Murad, Z1
Suleiman, AB2
Siegers, CP1
Klaassen, CD1
Plotz, PH1
Kimberly, RP1
Lin, JH1
Levy, G2
Hossain, M1
Nelson, EB1
Kleinknecht, D1
Perneger, TV1
Whelton, PK1
Klag, MJ1
Ronco, PM1
Flahault, A1
Martin, U2
Temple, RM3
Winney, RJ3
Barrett, BJ2
Blantz, RC1
Buckalew, VM1
Kliem, V1
Thon, W1
Krautzig, S1
Kolditz, M1
Behrend, M1
Pichlmayr, R1
Koch, KM1
Frei, U1
Brunkhorst, R1
Lee, HS1
Ti, TY1
Lye, WC1
Khoo, YM1
Tan, CC1
Talbott, GA1
Lynn, AM1
Levy, FH1
Zelikovic, I1
Schwarz, A3
Hörl, WH1
Farrell, J1
Schmitz, PG1
Dunn, JS1
Gault, MH2
Bach, PH1
Berndt, WO1
Delzell, E2
Dubach, U1
Finn, WF1
Fox, JM2
Hess, R1
Sandler, DP1
Trump, B1
Williams, G1
Preuschof, L1
Zellner, D1
Trinkhaus, J1
Nathan, J1
Beane, L1
Meltzer, B1
Feinstein, AR1
Heinemann, LA1
Curhan, GC1
Deschepper, PJ1
Graf, H1
Luft, FC1
Mihatsch, MJ1
Suissa, S1
Van Der Woude, F1
Willich, S1
Pintér, I1
Mátyus, J1
Czégány, Z1
Harsányi, J1
Homoki, M1
Kassai, M1
Kiss, E1
Kiss, I1
Ladányi, E1
Lócsey, L1
Major, L1
Misz, M1
Nagy, L1
Polner, K1
Rédl, J1
Solt, I1
Tichy, B1
Török, M1
Varga, G1
Wagner, G1
Wórum, I1
Zsoldos, B1
Pótó, L1
Wittmann, I1
Nagy, J1
Ejerblad, E1
Lindblad, P1
Dickman, PW1
Signorello, LB1
Lipworth, L1
Blot, WJ1
Zack, MM1
Crofford, LJ1
Thurlow, W1
Abrahams, C1
Furman, KI1
Salant, D1
Margetts, G1
Stewart, JH1
McCarthy, SW1
Storey, BG1
Roberts, BA1
Gallery, E1
Mahony, JF1
Char, VC1
Chandra, R1
Fletcher, AB1
Avery, GB1
Mathew, TH1
Main, J1
Ward, MK1
Hauser, AC1
Derfler, K1
Balcke, P1
Schoots, AC1
Koomen, GC1
Struijk, DG1
Krediet, RT1
Arisz, L1
Speirs, GC1
Critchley, JA1
Faber, U1
Glaeske, G1
Keller, F1
Offermann, G1
Forycki, Z1
Martens, F1
Thalhofer, S1
Ibe, K1
van Heyningen, R1
Harding, JJ1
Horne, EM1
Puvaneswary, M1
Rohana, A1
Campbell, RS1
Price, CP1
Bishop, J1
Znamirowska, MI1
Meltzer, AS1
Harrison, JF1
Parker, RW1
De Silva, KL1
Shahidi, NT1
Gabe, A1
Dubach, UC2
Koutsaimanis, KG1
de Wardener, HE1

Reviews

12 reviews available for acetaminophen and Chronic Kidney Failure

ArticleYear
Analgesia in patients with ESRD: a review of available evidence.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:2

    Topics: Acetaminophen; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anti-

2003
Paracetamol overdosage. Pharmacological considerations and clinical management.
    Drugs, 1983, Volume: 25, Issue:3

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Drug Interactions; Glutathione; Hear

1983
Acute effects of aspirin and acetaminophen on renal function.
    Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No

    Topics: Acetaminophen; Aspirin; Humans; Indomethacin; Kidney; Kidney Failure, Chronic; Liver Cirrhosis; Lupu

1981
Interstitial nephritis, the nephrotic syndrome, and chronic renal failure secondary to nonsteroidal anti-inflammatory drugs.
    Seminars in nephrology, 1995, Volume: 15, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Humans; Kidney Failure, C

1995
Acetaminophen and adverse chronic renal outcomes: an appraisal of the epidemiologic evidence.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:1 Suppl 1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Case-Control Studies; Female; Humans; Kidney Failure, Chron

1996
Acetaminophen: acute and chronic effects on renal function.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:1 Suppl 1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Humans; Kidney; Kidney Failure, Chronic

1996
Habitual use of acetaminophen as a risk factor for chronic renal failure: a comparison with phenacetin.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:1 Suppl 1

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Case-Control Studies; Drug Therapy, Combination

1996
Analgesic nephropathy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:3

    Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Canada; Drug Combinations; Drug Synergism; Humans; Kid

1998
A safety assessment of fixed combinations of acetaminophen and acetylsalicylic acid, coformulated with caffeine.
    Renal failure, 1998, Volume: 20, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine;

1998
Acetaminophen (Tylenol): Johnson & Johnson and consumer safety.
    The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics, 1997,Spring, Volume: 25, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Consumer Product Sa

1997
Relationship between nonphenacetin combined analgesics and nephropathy: a review. Ad Hoc Committee of the International Study Group on Analgesics and Nephropathy.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

2000
Drug-induced renal disease.
    The Medical journal of Australia, 1992, May-18, Volume: 156, Issue:10

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Angiotensin-Converting Enzyme Inhibitors; Anti-Infla

1992

Other Studies

60 other studies available for acetaminophen and Chronic Kidney Failure

ArticleYear
Treatment with Paracetamol Can Interfere with the Intradialytic Optical Estimation in Spent Dialysate of Uric Acid but Not of Indoxyl Sulfate.
    Toxins, 2022, 09-01, Volume: 14, Issue:9

    Topics: Acetaminophen; Dialysis Solutions; Hemodiafiltration; Humans; Indican; Kidney Failure, Chronic; Rena

2022
Pain Management in a Patient with Kidney Failure.
    Clinical journal of the American Society of Nephrology : CJASN, 2020, 11-06, Volume: 15, Issue:11

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste

2020
Pain management in patients with end-stage renal disease and calciphylaxis- a survey of clinical practices among physicians.
    BMC nephrology, 2020, 09-18, Volume: 21, Issue:1

    Topics: Acetaminophen; Advance Care Planning; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesic

2020
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure.
    Clinical journal of the American Society of Nephrology : CJASN, 2019, 06-07, Volume: 14, Issue:6

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain

2019
Possibility of decrease in CYP1A2 function in patients with end-stage renal disease.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2014, Volume: 18, Issue:2

    Topics: Acetaminophen; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Humans; Kidney Failure, Chronic; Li

2014
Risk of Acute Kidney Injury and Long-Term Outcome in Patients With Acetaminophen Intoxication: A Nationwide Population-Based Retrospective Cohort Study.
    Medicine, 2015, Volume: 94, Issue:46

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Databa

2015
Woman who was granted right to refuse kidney dialysis dies.
    BMJ (Clinical research ed.), 2015, Dec-03, Volume: 351

    Topics: Acetaminophen; Euthanasia, Passive; Expert Testimony; Female; Humans; Kidney Failure, Chronic; Menta

2015
Successful treatment of donor-derived hepatitis C viral infection in three transplant recipients from a donor at increased risk for bloodborne pathogens.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:2

    Topics: Acetaminophen; Adult; Allografts; Antiviral Agents; Benzimidazoles; Blood-Borne Pathogens; Chemical

2017
Acetaminophen, aspirin and progression of advanced chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Cohort Studies; Female; Follow-Up Stu

2009
Pain prevalence in patients with chronic kidney disease.
    Clinical nephrology, 2010, Volume: 73, Issue:4

    Topics: Acetaminophen; Activities of Daily Living; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory

2010
Analgesic use and the risk for progression of chronic kidney disease.
    Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin

2010
Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats.
    Life sciences, 2012, Dec-17, Volume: 91, Issue:25-26

    Topics: Acetaminophen; Adenine; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antioxidants; Disea

2012
Successful outcome of transplant of kidneys recovered from a brain-dead liver transplant recipient: case report.
    Progress in transplantation (Aliso Viejo, Calif.), 2012, Volume: 22, Issue:4

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Death; Humans; Kidney Failure,

2012
[Crohn's disease and renal amyloidosis. Acute renal failure].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:4

    Topics: Acetaminophen; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Amyloidosis; Analgesics, Non-Nar

2002
Analgesic prescription patterns among hemodialysis patients in the DOPPS: potential for underprescription.
    Kidney international, 2004, Volume: 65, Issue:6

    Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cycloo

2004
[Chronic interstitial nephritis in an 18-year-old due to intake of a compound analgesic].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Oct-15, Volume: 101, Issue:10

    Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Caffeine; Creat

2006
In memoriam 'analgesic nephropathy' (circa 1972-2006).
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:4

    Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Approval; History,

2007
The abuse of analgesics leading to nephropathy in South Africa.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Nov-17, Volume: 66, Issue:20

    Topics: Acetaminophen; Analgesics; Aspirin; Female; Humans; Kidney Failure, Chronic; Male; Phenacetin

1984
Analgesic nephropathy associated with paracetamol.
    Australian and New Zealand journal of medicine, 1984, Volume: 14, Issue:1

    Topics: Acetaminophen; Adult; Aged; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Functio

1984
Biliary excretion of acetaminophen in ureter-ligated rats.
    Pharmacology, 1984, Volume: 28, Issue:3

    Topics: Acetaminophen; Animals; Bile; Kidney Failure, Chronic; Ligation; Male; Rats; Rats, Inbred Strains; S

1984
Effect of experimental renal failure on sulfate retention and acetaminophen pharmacokinetics in rats.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:1

    Topics: Acetaminophen; Animals; Creatinine; Half-Life; Kidney Failure, Chronic; Kinetics; Male; Rats; Rats,

1982
Other factors may have contributed to epidemic of renal failure.
    BMJ (Clinical research ed.), 1995, Oct-07, Volume: 311, Issue:7010

    Topics: Acetaminophen; Bangladesh; Child; Child, Preschool; Disease Outbreaks; Humans; Kidney Failure, Chron

1995
Kidney failure and analgesic drugs.
    The New England journal of medicine, 1995, Jun-01, Volume: 332, Issue:22

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Confounding Factors, Epidemiologic; Humans;

1995
Risk of kidney failure associated with the use of acetaminophen, aspirin, and nonsteroidal antiinflammatory drugs.
    The New England journal of medicine, 1994, Dec-22, Volume: 331, Issue:25

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Causal

1994
Drug-induced end-stage renal disease.
    The New England journal of medicine, 1994, Dec-22, Volume: 331, Issue:25

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Bias; Humans; Kidney Failure, Chronic; Risk

1994
The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Cysteine; Drug Administration Schedule; Female; Humans;

1993
High mortality from urothelial carcinoma despite regular tumor screening in patients with analgesic nephropathy after renal transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1996, Volume: 9, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesics; Carcinoma, Renal Cell; Female; Humans; Kidney Failure, Chron

1996
Paracetamol and its metabolites in saliva and plasma in chronic dialysis patients.
    British journal of clinical pharmacology, 1996, Volume: 41, Issue:1

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Female; Humans; Kidney Failure, Chronic; Male;

1996
Respiratory arrest precipitated by codeine in a child with chronic renal failure.
    Clinical pediatrics, 1997, Volume: 36, Issue:3

    Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Codein

1997
[Nephrotoxicity of analgesic combination preparations].
    Wiener klinische Wochenschrift, 1997, Apr-11, Volume: 109, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Humans; Kidney Failur

1997
[Comment on the contribution: "Usefulness of fixed analgesic combinations exemplified by thomapyrin"].
    Wiener klinische Wochenschrift, 1997, Apr-11, Volume: 109, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Humans; Kidney Failur

1997
Paracetamol-induced pancreatitis and fulminant hepatitis in a hemodialysis patient.
    Clinical nephrology, 1997, Volume: 48, Issue:2

    Topics: Acetaminophen; Acute Disease; Aged; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury

1997
Analgesic nephropathy, a form of chronic renal disease.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Humans; Kidney Failure, Chronic

1998
Incidence of analgesic nephropathy in Berlin since 1983.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:1

    Topics: Acetaminophen; Age Factors; Aged; Analgesics; Berlin; Diabetes Mellitus, Type 1; Diabetes Mellitus,

1999
[Analgesics-induced chronic renal failure in patients on dialysis therapy in Hungary].
    Orvosi hetilap, 2001, May-13, Volume: 142, Issue:19

    Topics: Acetaminophen; Adult; Aged; Amphetamine; Analgesics; Aspirin; Caffeine; Codeine; Female; Humans; Hun

2001
Acetaminophen, aspirin, and chronic renal failure.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Cas

2001
Rational use of analgesic and antiinflammatory drugs.
    The New England journal of medicine, 2001, Dec-20, Volume: 345, Issue:25

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxyg

2001
Acetaminophen, aspirin, and renal failure.
    The New England journal of medicine, 2002, May-16, Volume: 346, Issue:20

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; K

2002
Dermal micro-angiopathy in patients with analgesic nephropathy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Sep-02, Volume: 54, Issue:10

    Topics: Acetaminophen; Acute Kidney Injury; Adult; Aged; Capillaries; Female; Humans; Kidney Failure, Chroni

1978
Phenacetin and paracetamol.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Anemia, Hemolytic; Central Nervous System; Chemical Phenomena; Chemistry; Humans; Kid

1976
Diseases causing end-stage renal failure in New South Wales.
    British medical journal, 1975, Feb-22, Volume: 1, Issue:5955

    Topics: Acetaminophen; Adult; Analgesics; Aspirin; Australia; Caffeine; Codeine; Cystoscopy; Female; Glomeru

1975
Letter: Polyhydramnios and neonatal renal failure--a possible association with maternal acetaminophen ingestion.
    The Journal of pediatrics, 1975, Volume: 86, Issue:4

    Topics: Acetaminophen; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kidney Failure, C

1975
Potentiation of aluminium absorption by effervescent analgesic tablets in a haemodialysis patient.
    BMJ (Clinical research ed.), 1992, Jun-27, Volume: 304, Issue:6843

    Topics: Acetaminophen; Aluminum; Aluminum Hydroxide; Analgesics; Citrates; Codeine; Drug Combinations; Drug

1992
The disposition of paracetamol and the accumulation of its glucuronide and sulphate conjugates during multiple dosing in patients with chronic renal failure.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Aged; Biotransformation; Female; Glucuronates; Humans; Kidney Fail

1991
Progression of renal insufficiency in analgesic nephropathy: impact of continuous drug abuse.
    Journal of clinical epidemiology, 1991, Volume: 44, Issue:1

    Topics: Acetaminophen; Adult; Aged; Analgesics; Austria; Creatinine; Female; Humans; Kidney Failure, Chronic

1991
Isolation, identification, and analysis of 4-acetylaminophenol-glucuronide in body fluids of dialyzed renal patients; a molecular mass marker for peritoneal diffusive transport.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Apr-13, Volume: 188, Issue:1

    Topics: Acetaminophen; Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Dialysis Solutions; Di

1990
Paracetamol disposition and metabolite kinetics in patients with chronic renal failure.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:3

    Topics: Acetaminophen; Adult; Aged; Female; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Male; Middle

1989
Analgesic nephropathy in West Germany.
    Lancet (London, England), 1986, Jan-25, Volume: 1, Issue:8474

    Topics: Acetaminophen; Drug Therapy, Combination; Female; Germany, West; Humans; Kidney Diseases; Kidney Fai

1986
Tranquilizers, analgetics and antidepressants in patients treated with hemodialysis.
    Blood purification, 1985, Volume: 3, Issue:1-3

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Benzodia

1985
Do aspirin-like analgesics protect against cataract? A case-control study.
    Lancet (London, England), 1986, May-17, Volume: 1, Issue:8490

    Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F

1986
Paracetamol: a bitter pill.
    Professional nurse (London, England), 1989, Volume: 4, Issue:5

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Humans; Kidney Failure, Chronic

1989
Paracetamol: a cause for analgesic nephropathy and end-stage renal disease.
    Nephron, 1988, Volume: 50, Issue:1

    Topics: Acetaminophen; Adult; Aged; Calcinosis; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Ma

1988
Sulfate conjugation in drug metabolism: role of inorganic sulfate.
    Federation proceedings, 1986, Volume: 45, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Animals; Arylsulfotransferase; Biotransformation; Chemical and Drug I

1986
Experience with an homogeneous immunoassay for paracetamol (acetaminophen).
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1986, Volume: 24, Issue:2

    Topics: Acetaminophen; Antidotes; Hemolysis; Humans; Immunoenzyme Techniques; Indicators and Reagents; Kidne

1986
Regulations controlling the sale of mild analgesics in Canada.
    Canadian Medical Association journal, 1972, Oct-21, Volume: 107, Issue:8

    Topics: Acetaminophen; Analgesics; Canada; Drug and Narcotic Control; Drug Prescriptions; Humans; Kidney Fai

1972
Lysozymuria and acute disorders of renal function.
    Journal of clinical pathology, 1973, Volume: 26, Issue:4

    Topics: Acetaminophen; Acute Disease; Aspirin; Electroshock; Glomerulonephritis; Heart Failure; Humans; Hypo

1973
The effect of acetylsalicylic acid, caffeine, and codeine on the excretion of phenacetin metabolites.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:8

    Topics: Acetaminophen; Aniline Compounds; Aspirin; Caffeine; Chromatography, Thin Layer; Codeine; Creatinine

1972
[Determination and elimination of N-acetyl-p-aminophenol depending on kidney function following administration of phenacetin].
    Helvetica medica acta. Supplementum, 1967, May-28, Volume: 47

    Topics: Acetaminophen; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Failure, Chron

1967
Phenacetin nephropathy, with particular reference to the effect of surgery.
    British medical journal, 1970, Oct-17, Volume: 4, Issue:5728

    Topics: Acetaminophen; Adult; Creatinine; England; Female; Hematuria; Humans; Hypertension, Renal; Kidney Di

1970
[Absorption, destination and excretion of phenacetin and N-acetyl-p-aminophenol in renal insufficiency].
    Klinische Wochenschrift, 1968, Mar-01, Volume: 46, Issue:5

    Topics: Acetaminophen; Adult; Creatinine; Female; Humans; Intestinal Absorption; Kidney; Kidney Failure, Chr

1968