Page last updated: 2024-10-22

acetaminophen and Chronic Hepatitis B

acetaminophen has been researched along with Chronic Hepatitis B in 5 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Phenacetin pharmacokinetics and the recovery of its urinary metabolites were studied in 8 normal subjects, 16 patients with chronic hepatitis B and 12 patients with cirrhosis."5.12Impaired clearance of phenacetin in hepatic cirrhosis and fibrosis. ( He, P; Li, XD; Liu, HL; Qu, ZQ; Wu, MC; Zhang, X, 2007)
" Despite abundant experimental data showing that fatty liver is more susceptible to liver injury, drug-induced liver disease seems no more frequent in NAFLD patients, except, possibly, a higher incidence but not severity of acetaminophen hepatotoxicity."4.90The impact of obesity and metabolic syndrome on chronic hepatitis B and drug-induced liver disease. ( Pais, R; Ratziu, V; Rusu, E, 2014)
" This review summarises the evidence for potential therapeutic applications of non-immunosuppressive cyclophilin inhibitors, alone or in combination with other agents, in virus-induced liver diseases like hepatitis C, B or Delta, liver inflammation and fibrosis, acetaminophen-induced liver toxicity and hepatocellular carcinoma."4.90Cyclophilin inhibition as potential therapy for liver diseases. ( Naoumov, NV, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pais, R1
Rusu, E1
Ratziu, V1
Weerasinghe, SV1
Jang, YJ1
Fontana, RJ1
Omary, MB1
Naoumov, NV1
Wang, XR1
Qu, ZQ2
Li, XD2
Liu, HL2
He, P2
Fang, BX1
Xiao, J1
Huang, W1
Wu, MC2
Zhang, X1

Reviews

2 reviews available for acetaminophen and Chronic Hepatitis B

ArticleYear
The impact of obesity and metabolic syndrome on chronic hepatitis B and drug-induced liver disease.
    Clinics in liver disease, 2014, Volume: 18, Issue:1

    Topics: Acetaminophen; Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; He

2014
Cyclophilin inhibition as potential therapy for liver diseases.
    Journal of hepatology, 2014, Volume: 61, Issue:5

    Topics: Acetaminophen; Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cyclophil

2014

Trials

1 trial available for acetaminophen and Chronic Hepatitis B

ArticleYear
Impaired clearance of phenacetin in hepatic cirrhosis and fibrosis.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:1

    Topics: Acetaminophen; Area Under Curve; Biotransformation; Carcinoma, Hepatocellular; Chemoembolization, Th

2007

Other Studies

2 other studies available for acetaminophen and Chronic Hepatitis B

ArticleYear
Carbamoyl phosphate synthetase-1 is a rapid turnover biomarker in mouse and human acute liver injury.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Aug-01, Volume: 307, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Animals; Apoptosis; Biomarkers; Carbamoyl-Phosphate Synthase (A

2014
Activity of sulfotransferase 1A1 is dramatically upregulated in patients with hepatocellular carcinoma secondary to chronic hepatitis B virus infection.
    Cancer science, 2010, Volume: 101, Issue:2

    Topics: Acetaminophen; Adult; Aged; Arylsulfotransferase; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A2

2010