Page last updated: 2024-10-22

acetaminophen and Cerebral Palsy

acetaminophen has been researched along with Cerebral Palsy in 6 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery."9.24Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017)
" We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child."7.88Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018)
"The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery."5.24Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017)
" We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child."3.88Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018)
"To investigate if chronic pain in children with cerebral palsy is undertreated with the current pharmacological/non-pharmacological interventions using a pain management index."1.91Presence and grade of undertreatment of pain in children with cerebral palsy. ( Sultan, T; Wong, C, 2023)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Sultan, T1
Wong, C1
Petersen, TG1
Liew, Z1
Andersen, AN1
Andersen, GL1
Andersen, PK1
Martinussen, T1
Olsen, J1
Rebordosa, C1
Tollånes, MC1
Uldall, P1
Wilcox, AJ1
Strandberg-Larsen, K1
Rashid, A1
Ozkan, D1
Gonen, E1
Akkaya, T1
Bakir, M1
Tubbs, RS1
Law, C1
Davis, D1
Shoja, MM1
Acakpo-Satchivi, L1
Wellons, JC1
Blount, JP1
Oakes, WJ1
Darienzo, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Postoperative Pain Management in Pediatric Patients With Cerebral Palsy - Comparative Observational Study"[NCT05252650]130 participants (Anticipated)Observational2022-02-15Recruiting
Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy[NCT02507700]60 participants (Actual)Interventional2015-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for acetaminophen and Cerebral Palsy

ArticleYear
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
    Journal of anesthesia, 2017, Volume: 31, Issue:3

    Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool

2017
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
    Journal of anesthesia, 2017, Volume: 31, Issue:3

    Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool

2017
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
    Journal of anesthesia, 2017, Volume: 31, Issue:3

    Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool

2017
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
    Journal of anesthesia, 2017, Volume: 31, Issue:3

    Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool

2017
Muscle relaxant-analgesic therapy (report on institutionalized spastic children).
    Diseases of the nervous system, 1966, Volume: 27, Issue:3

    Topics: Acetaminophen; Cerebral Palsy; Child, Preschool; Chlorzoxazone; Clinical Trials as Topic; Female; Hu

1966

Other Studies

4 other studies available for acetaminophen and Cerebral Palsy

ArticleYear
Presence and grade of undertreatment of pain in children with cerebral palsy.
    Scandinavian journal of pain, 2023, 07-26, Volume: 23, Issue:3

    Topics: Acetaminophen; Adaptation, Psychological; Adolescent; Adult; Cerebral Palsy; Child; Child, Preschool

2023
Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child.
    International journal of epidemiology, 2018, 02-01, Volume: 47, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Cerebral Palsy; Cohort Studies; Female; Hum

2018
Paracetamol, ethnic health inequalities, cerebral palsy, and pornography.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2015, Volume: 65, Issue:633

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cerebral Palsy; Erotica; Ethnicity; Healthcare Dispa

2015
Scheduled oral analgesics and the need for opiates in children following partial dorsal rhizotomy.
    Journal of neurosurgery, 2007, Volume: 106, Issue:6 Suppl

    Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Cerebral P

2007