acetaminophen has been researched along with Carcinoma, Renal Cell in 13 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was no evidence of a dose-response for duration of use of paracetamol (linear trend p = 0." | 1.62 | Analgesic use and the risk of renal cell carcinoma - Findings from the Consortium for the Investigation of Renal Malignancies (CONFIRM) study. ( Aitken, T; Bassett, JK; Bruinsma, FJ; Carroll, R; Davis, ID; Dudding-Byth, T; English, DR; Giles, GG; Jefford, M; Jenkins, M; Jordan, S; MacInnis, RJ; Milne, RL; Severi, G; Tucker, K; Walsh, J; Winship, I, 2021) |
| " There was a dose-response relationship between duration of nonaspirin NSAID use and RCC risk; compared with nonregular use, the pooled multivariate relative risks were 0." | 1.37 | Prospective evaluation of analgesic use and risk of renal cell cancer. ( Atkins, MB; Cho, E; Choueiri, TK; Curhan, G; Hankinson, SE; Kantoff, P; Stampfer, M, 2011) |
| " We report a severely malnourished 53-year-old woman who developed severe hepatotoxicity whilst receiving paracetamol at recommended dosage (4 g daily) following a period of fasting, in the absence of enzyme-inducing agents." | 1.32 | Paracetamol-induced hepatotoxicity at recommended dosage. ( Kurtovic, J; Riordan, SM, 2003) |
| "Although heavy or long-term use of analgesics has been related to risk of renal cell cancer in several studies, evidence for such an association remains inconclusive." | 1.29 | Use of analgesics and risk of renal cell cancer. ( Chow, WH; Linet, MS; Mandel, JS; McLaughlin, JK; Niwa, S, 1994) |
| " Long-term use (greater than 36 mo) of phenacetin-containing products was associated in both sexes with a twofold increased risk for renal cell cancer." | 1.27 | Relation of analgesic use to renal cancer: population-based findings. ( Blot, WJ; Fraumeni, JF; McLaughlin, JK; Mehl, ES, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bruinsma, FJ | 1 |
| Jordan, S | 1 |
| Bassett, JK | 1 |
| Severi, G | 1 |
| MacInnis, RJ | 1 |
| Walsh, J | 1 |
| Aitken, T | 1 |
| Jenkins, M | 1 |
| Carroll, R | 1 |
| Jefford, M | 1 |
| Davis, ID | 1 |
| Tucker, K | 1 |
| Dudding-Byth, T | 1 |
| English, DR | 1 |
| Giles, GG | 1 |
| Winship, I | 1 |
| Milne, RL | 1 |
| Cho, E | 1 |
| Curhan, G | 1 |
| Hankinson, SE | 1 |
| Kantoff, P | 1 |
| Atkins, MB | 1 |
| Stampfer, M | 1 |
| Choueiri, TK | 1 |
| Fenner, A | 1 |
| Kurtovic, J | 1 |
| Riordan, SM | 1 |
| McCredie, M | 2 |
| Pommer, W | 1 |
| McLaughlin, JK | 3 |
| Stewart, JH | 2 |
| Lindblad, P | 1 |
| Mandel, JS | 2 |
| Mellemgaard, A | 1 |
| Schlehofer, B | 1 |
| Niwa, S | 2 |
| Chow, WH | 1 |
| Linet, MS | 1 |
| Day, NE | 1 |
| Vanchieri, C | 1 |
| Kliem, V | 1 |
| Thon, W | 1 |
| Krautzig, S | 1 |
| Kolditz, M | 1 |
| Behrend, M | 1 |
| Pichlmayr, R | 1 |
| Koch, KM | 1 |
| Frei, U | 1 |
| Brunkhorst, R | 1 |
| Rosenberg, L | 1 |
| Rao, RS | 1 |
| Palmer, JR | 1 |
| Strom, BL | 1 |
| Zauber, A | 1 |
| Warshauer, ME | 1 |
| Stolley, PD | 1 |
| Shapiro, S | 1 |
| Gago-Dominguez, M | 1 |
| Yuan, JM | 1 |
| Castelao, JE | 1 |
| Ross, RK | 1 |
| Yu, MC | 1 |
| Fosså, SD | 1 |
| De Garis, ST | 1 |
| Blot, WJ | 1 |
| Mehl, ES | 1 |
| Fraumeni, JF | 1 |
13 other studies available for acetaminophen and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Analgesic use and the risk of renal cell carcinoma - Findings from the Consortium for the Investigation of Renal Malignancies (CONFIRM) study.
Topics: Acetaminophen; Analgesics; Australia; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms | 2021 |
Prospective evaluation of analgesic use and risk of renal cell cancer.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, R | 2011 |
Kidney cancer: long-term use of nonaspirin NSAIDs increases RCC risk.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Renal Cell; Follow-Up Studies; Hu | 2011 |
Paracetamol-induced hepatotoxicity at recommended dosage.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anus Neoplasms; Brachytherapy; Carcinoma, Renal Cell; Chemi | 2003 |
International renal-cell cancer study. II. Analgesics.
Topics: Acetaminophen; Age Factors; Carcinoma, Renal Cell; Case-Control Studies; Dose-Response Relationship, | 1995 |
Use of analgesics and risk of renal cell cancer.
Topics: Acetaminophen; Adult; Aged; Aspirin; Carcinoma, Renal Cell; Case-Control Studies; Drug Combinations; | 1994 |
Different roles for phenacetin and paracetamol in cancer of the kidney and renal pelvis.
Topics: Acetaminophen; Adult; Aged; Aspirin; Carcinoma, Renal Cell; Case-Control Studies; Drug Combinations; | 1993 |
Australian study links certain analgesics to renal cancers.
Topics: Acetaminophen; Australia; Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Phenacetin; Risk | 1993 |
High mortality from urothelial carcinoma despite regular tumor screening in patients with analgesic nephropathy after renal transplantation.
Topics: Acetaminophen; Adult; Aged; Analgesics; Carcinoma, Renal Cell; Female; Humans; Kidney Failure, Chron | 1996 |
Transitional cell cancer of the urinary tract and renal cell cancer in relation to acetaminophen use (United States).
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Carcinoma, Renal Cell; Carcinoma, Transitional | 1998 |
Regular use of analgesics is a risk factor for renal cell carcinoma.
Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Carcinoma, Renal Cell; Case-Control Studies; Dose-R | 1999 |
Further experience with recombinant interferon alfa-2a with vinblastine in metastatic renal cell carcinoma: a progress report.
Topics: Acetaminophen; Adult; Aged; Carcinoma, Renal Cell; Combined Modality Therapy; Dose-Response Relation | 1987 |
Relation of analgesic use to renal cancer: population-based findings.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; | 1985 |