acetaminophen has been researched along with Cancer of Prostate in 16 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary outcome was a reduction in postoperative pain as assessed by a visual analogue scale (VAS)." | 2.78 | Intravesical ropivacaine as a novel means of analgesia post-robot-assisted radical prostatectomy: a randomized, double-blind, placebo-controlled trial. ( Fuller, A; Martin, PR; Nott, L; Pautler, SE; Vanderhaeghe, L, 2013) |
| "We investigated postoperative pain intensity and additional analgesic consumption on postoperative day 0, 1, 2, 3, and 5 between the two groups." | 1.62 | Postoperative around-the-clock administration of intravenous acetaminophen for pain control following robot-assisted radical prostatectomy. ( Hayashi, T; Hieda, K; Inoue, S; Miyoshi, H; Teishima, J; Tsutsumi, YM, 2021) |
| "Abdominal pain was generally moderate for most patients and decreased significantly after about 4 days." | 1.40 | Pain and analgesic use after robot-assisted radical prostatectomy. ( Badani, KK; Bergman, A; Korets, R; Motamedinia, P; Shapiro, EY; Weinberg, AC; Woldu, SL, 2014) |
| "One hundred forty-one prostate cancer cases diagnosed between 1980 and May 2004 were confirmed by medical record review." | 1.33 | Nonsteroidal anti-inflammatory drugs and risk of prostate cancer in the Baltimore Longitudinal Study of Aging. ( Carter, HB; Corrada, MM; De Marzo, AM; Landis, PK; Metter, EJ; Pearson, JD; Platz, EA; Rohrmann, S; Watson, DJ, 2005) |
| "Aspirin use was associated with a reduced risk of prostate cancer [odds ratio (OR) = 0." | 1.32 | Inverse association between nonsteroidal anti-inflammatory drugs and prostate cancer. ( García Rodríguez, LA; González-Pérez, A, 2004) |
| "Ibuprofen was significantly more effective against human prostate cancer cells in vitro than the other tested nonprescription NSAIDs." | 1.31 | Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells. ( Andrews, J; Andrews, P; Djakiew, D; Krygier, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| De Petrocellis, L | 1 |
| Arroyo, FJ | 1 |
| Orlando, P | 1 |
| Schiano Moriello, A | 1 |
| Vitale, RM | 1 |
| Amodeo, P | 1 |
| Sánchez, A | 1 |
| Roncero, C | 1 |
| Bianchini, G | 1 |
| Martín, MA | 1 |
| López-Alvarado, P | 1 |
| Menéndez, JC | 1 |
| Inoue, S | 1 |
| Miyoshi, H | 1 |
| Hieda, K | 1 |
| Hayashi, T | 1 |
| Tsutsumi, YM | 1 |
| Teishima, J | 1 |
| Lycken, M | 1 |
| Drevin, L | 1 |
| Garmo, H | 1 |
| Stattin, P | 1 |
| Adolfsson, J | 1 |
| Lissbrant, IF | 1 |
| Holmberg, L | 1 |
| Bill-Axelson, A | 1 |
| Woldu, SL | 1 |
| Weinberg, AC | 1 |
| Bergman, A | 1 |
| Shapiro, EY | 1 |
| Korets, R | 1 |
| Motamedinia, P | 1 |
| Badani, KK | 1 |
| Miura, T | 1 |
| Singer, EA | 1 |
| Palapattu, GS | 1 |
| van Wijngaarden, E | 1 |
| Doyle, CA | 1 |
| Loadsman, JA | 1 |
| Hruby, G | 1 |
| Visapää, H | 1 |
| Taari, K | 1 |
| Murad, AS | 1 |
| Down, L | 1 |
| Davey Smith, G | 1 |
| Donovan, JL | 1 |
| Athene Lane, J | 1 |
| Hamdy, FC | 1 |
| Neal, DE | 1 |
| Martin, RM | 1 |
| Jacobs, EJ | 1 |
| Newton, CC | 1 |
| Stevens, VL | 1 |
| Gapstur, SM | 1 |
| Yao, F | 1 |
| Coquery, J | 1 |
| Lê Cao, KA | 1 |
| Schenk, JM | 1 |
| Calip, GS | 1 |
| Tangen, CM | 1 |
| Goodman, P | 1 |
| Parsons, JK | 1 |
| Thompson, IM | 1 |
| Kristal, AR | 1 |
| Fuller, A | 1 |
| Vanderhaeghe, L | 1 |
| Nott, L | 1 |
| Martin, PR | 1 |
| Pautler, SE | 1 |
| Andrews, J | 1 |
| Djakiew, D | 1 |
| Krygier, S | 1 |
| Andrews, P | 1 |
| García Rodríguez, LA | 1 |
| González-Pérez, A | 1 |
| Platz, EA | 1 |
| Rohrmann, S | 1 |
| Pearson, JD | 1 |
| Corrada, MM | 1 |
| Watson, DJ | 1 |
| De Marzo, AM | 1 |
| Landis, PK | 1 |
| Metter, EJ | 1 |
| Carter, HB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Evaluating the Use of Perioperative Intravenous Lidocaine Infusion to Decrease Pain Scores and Opioid Consumption After Robotic-Assisted Prostatectomy and Robotic-Assisted Partia[NCT03824808] | Phase 4 | 21 participants (Actual) | Interventional | 2019-02-26 | Terminated (stopped due to Challenges with recruitment of surgical research subjects in the target population.) | ||
| THE EFFECT OF ULTRASOUND GUIDED RECTUS SHEATH BLOCK ON POSTOPERATIVE ANALGESIA AND URETHRAL CATHETER PAIN IN ROBOTIC PROSTATECTOMY OPERATIONS: A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL[NCT05242198] | 60 participants (Actual) | Interventional | 2022-03-15 | Completed | |||
| Ultrasound Guided External Oblique Intercostal Plane Block vs. Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy: Prospective Randomized Study[NCT05632991] | 80 participants (Anticipated) | Interventional | 2022-12-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Difference in time in the Post Anesthesia Care Unit (PACU) after surgery (NCT03824808)
Timeframe: During hospitalization, approximately 2 hours post-surgery
| Intervention | Minutes (Mean) |
|---|---|
| Treatment Group | 59 |
| Control Group | 122.5 |
"10-cm Visual Analog Scale (VAS), score of 0 no pain to a score of 10 worst pain ever" (NCT03824808)
Timeframe: Through study completion, assessed at 1h, 2h, 4h, 6h, 12h and 24h post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | score on a scale (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pain 1 hour post operative | Pain 2 hours post operative | Pain 4 hours post operative | Pain 6 hours post operative | Pain 12 hours post operative | Pain 24 hours post operative | Pain 48 hours post operative | Pain 72 hours post operative | Pain 96 hours post operative | Pain 120 hours post operative | Pain on discharge | Pain at post operative visit | |
| Treatment Group | 5.5 | 4.4 | 4.8 | 4.0 | 3.6 | 2.3 | 2.5 | 5 | 6 | 5 | 1 | 0.5 |
"10-cm Visual Analog Scale (VAS), score of 0 no pain to a score of 10 worst pain ever" (NCT03824808)
Timeframe: Through study completion, assessed at 1h, 2h, 4h, 6h, 12h and 24h post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | score on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Pain 1 hour post operative | Pain 2 hours post operative | Pain 4 hours post operative | Pain 6 hours post operative | Pain 12 hours post operative | Pain 24 hours post operative | Pain 48 hours post operative | Pain on discharge | Pain at post operative visit | |
| Control Group | 4.0 | 4.2 | 3.1 | 2.5 | 2.4 | 1.9 | 2 | 2 | 0.5 |
Difference in opioid consumption in first 24 hours, discharge and 21 days post-operatively (morphine equivalents) (NCT03824808)
Timeframe: Through study completion, assessed for first 24-hours post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | Milligram Morphine Equivalent (Mean) | |||
|---|---|---|---|---|
| Milligram morphine equivalent (MME) 0-24h postop | Milligram morphine equivalent (MME) 25-48h postop | Milligram morphine equivalent (MME) prescribed at discharge for home use | Milligram morphine equivalent (MME) used of discharge prescription | |
| Control Group | 12.0 | 21.3 | 23.0 | 8.8 |
Difference in opioid consumption in first 24 hours, discharge and 21 days post-operatively (morphine equivalents) (NCT03824808)
Timeframe: Through study completion, assessed for first 24-hours post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | Milligram Morphine Equivalent (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Milligram morphine equivalent (MME) 0-24h postop | Milligram morphine equivalent (MME) 25-48h postop | Milligram morphine equivalent (MME) 49-72h postop | Milligram morphine equivalent (MME) 73-96h postop | Milligram morphine equivalent (MME) 97-120h postop | Milligram morphine equivalent (MME) prescribed at discharge for home use | Milligram morphine equivalent (MME) used of discharge prescription | |
| Treatment Group | 22.5 | 26.3 | 7.5 | 7.5 | 7.5 | 26.8 | 20.0 |
3 trials available for acetaminophen and Cancer of Prostate
| Article | Year |
|---|---|
Associations of aspirin, nonsteroidal anti-inflammatory drug and paracetamol use with PSA-detected prostate cancer: findings from a large, population-based, case-control study (the ProtecT study).
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cas | 2011 |
Indications for and use of nonsteroidal antiinflammatory drugs and the risk of incident, symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cohort Studies; Co | 2012 |
Intravesical ropivacaine as a novel means of analgesia post-robot-assisted radical prostatectomy: a randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Administration, Intravesical; Aged; Amides; Analgesia; Anesthetics, Local; Double-Bli | 2013 |
13 other studies available for acetaminophen and Cancer of Prostate
| Article | Year |
|---|---|
Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
Topics: Animals; Antineoplastic Agents; Calcium; Cell Proliferation; Diketopiperazines; Dose-Response Relati | 2016 |
Postoperative around-the-clock administration of intravenous acetaminophen for pain control following robot-assisted radical prostatectomy.
Topics: Acetaminophen; Administration, Intravenous; Aged; Female; Humans; Male; Middle Aged; Pain, Postopera | 2021 |
The use of palliative medications before death from prostate cancer: Swedish population-based study with a comparative overview of European data.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Androgen Antagonists; Anti-Inflammatory | 2018 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
[Palliative medicine--drug therapy for cancer pain].
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Male; Pain; Pall | 2016 |
Prostate-specific antigen levels in relation to consumption of nonsteroidal anti-inflammatory drugs and acetaminophen: results from the 2001-2002 National Health and Nutrition Examination Survey.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2008 |
An audit of analgesia requirements for high-dose-rate prostate brachytherapy.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, | 2008 |
Combination of paracetamol, codeine and lidocaine for pain relief during transrectal ultrasound guided biopsy of the prostate.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Biopsy, Needle; Code | 2009 |
A large cohort study of long-term acetaminophen use and prostate cancer incidence.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Cohort Studies; Humans; Inc | 2011 |
Independent Principal Component Analysis for biologically meaningful dimension reduction of large biological data sets.
Topics: Acetaminophen; Algorithms; Animals; Artifacts; Cluster Analysis; Computational Biology; Humans; Male | 2012 |
Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Divis | 2002 |
Inverse association between nonsteroidal anti-inflammatory drugs and prostate cancer.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cohort | 2004 |
Nonsteroidal anti-inflammatory drugs and risk of prostate cancer in the Baltimore Longitudinal Study of Aging.
Topics: Acetaminophen; Aged; Aging; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2005 |