Page last updated: 2024-10-22

acetaminophen and Cancer of Colon

acetaminophen has been researched along with Cancer of Colon in 18 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"To examine the relation between the use of aspirin and non-steroidal anti-inflammatory drugs and the presence of asymptomatic colorectal adenomas."9.07Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme. ( Hardcastle, JD; Hawtin, PG; Little, J; Logan, RF, 1993)
"To examine the relation between the use of aspirin and non-steroidal anti-inflammatory drugs and the presence of asymptomatic colorectal adenomas."5.07Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme. ( Hardcastle, JD; Hawtin, PG; Little, J; Logan, RF, 1993)
"Four hundred eighty-three women with ovarian cancer and 1877 women matched for age, years of medical history in computer record, general practice attended, and calendar time; 3706 women with breast cancer and 14,155 matched control subjects; and 635 women with colon cancer and 2434 matched control subjects."1.31Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancer. ( Jick, H; Meier, CR; Schmitz, S, 2002)
"We have reported reduced risk of fatal colon cancer among persons who used aspirin in a large prospective study."1.29Aspirin use and risk of fatal cancer. ( Calle, EE; Flanders, WD; Heath, CW; Namboodiri, MM; Thun, MJ, 1993)
"Death rates from colon cancer were measured through 1988."1.28Aspirin use and reduced risk of fatal colon cancer. ( Heath, CW; Namboodiri, MM; Thun, MJ, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's8 (44.44)18.2507
2000's3 (16.67)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tung, EE1
Litin, SC1
Bundrick, JB1
Bundscherer, AC1
Malsy, M1
Gruber, MA1
Graf, BM1
Sinner, B1
Torup, H1
Hansen, EG1
Bøgeskov, M1
Rosenberg, J1
Mitchell, AU1
Petersen, PL1
Mathiesen, O1
Dahl, JB1
Møller, AM1
Frey, J1
van der Linden, J1
Bolanowska, W1
Gessner, T1
Wargovich, MJ1
Chen, CD1
Harris, C1
Yang, E1
Velasco, M1
Muscat, JE1
Stellman, SD1
Wynder, EL1
Logan, RF1
Little, J1
Hawtin, PG1
Hardcastle, JD1
Thun, MJ2
Namboodiri, MM2
Calle, EE1
Flanders, WD1
Heath, CW2
Gelpi, JR1
Dorsey-Tyler, K1
Luchtefeld, MA1
Senagore, AJ1
Schwenger, P1
Alpert, D1
Skolnik, EY1
Vilcek, J1
Franklin, ME1
Díaz-E, JA1
Abrego, D1
Parra-Dávila, E1
Glass, JL1
Meier, CR1
Schmitz, S1
Jick, H1
Williams, GM1
Iatropoulos, MJ1
Jeffrey, AM1
Shirai, T1
Travers, JD1
Temple, AR1
Gates, TN1
Falk, P1
Holgersson, J1
Jovall, PA1
Karlsson, KA1
Strömberg, N1
Thurin, J1
Brodin, T1
Sjögren, HO1
McLean, AE1
Driver, HE1
McDanell, R1
Tacchi-Bedford, AM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Transversus Abdominis Plane (TAP) Block as Postoperative Pain Management After Laparoscopic Colon Surgery[NCT01418144]Phase 480 participants (Actual)Interventional2010-08-31Completed
The Yield and Safety of Screening and Surveillance Colonoscopy in Elderly Patients (> 80 Years)[NCT00590434]169 participants (Actual)Observational2006-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetaminophen and Cancer of Colon

ArticleYear
The influence of diet on activation and inactivation of chemicals--evidence from animals and man.
    Developments in toxicology and environmental science, 1986, Volume: 12

    Topics: 1,2-Dimethylhydrazine; Acetaminophen; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Co

1986

Trials

2 trials available for acetaminophen and Cancer of Colon

ArticleYear
Transversus abdominis plane block after laparoscopic colonic resection in cancer patients: A randomised clinical trial.
    European journal of anaesthesiology, 2016, Volume: 33, Issue:10

    Topics: Abdominal Muscles; Acetaminophen; Aged; Colectomy; Colonic Neoplasms; Denmark; Double-Blind Method;

2016
Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme.
    BMJ (Clinical research ed.), 1993, Jul-31, Volume: 307, Issue:6899

    Topics: Acetaminophen; Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies

1993

Other Studies

15 other studies available for acetaminophen and Cancer of Colon

ArticleYear
Clinical Pearls in Geriatrics.
    Disease-a-month : DM, 2017, Volume: 63, Issue:6

    Topics: Acetaminophen; Aged; Aged, 80 and over; Automobile Driving; Cognition Disorders; Cognitive Dysfuncti

2017
Acetaminophen and Metamizole Induce Apoptosis in HT 29 and SW 480 Colon Carcinoma Cell Lines
    Anticancer research, 2018, Volume: 38, Issue:2

    Topics: Acetaminophen; Aminopyrine; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Apopt

2018
Limitations regarding double-blinding, adherence to the intention to treat principle, and postoperative dosage of paracetamol.
    Annals of surgery, 2011, Volume: 254, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Carbon Dioxide; Colonic Neoplasms; Dose-Response Relationsh

2011
Drug interactions with acetaminophen: effects of phenobarbital, prednisone and 5-fluorouracil in normal and tumor-bearing rats.
    Biochemical pharmacology, 1980, Apr-15, Volume: 29, Issue:8

    Topics: Acetaminophen; Animals; Colonic Neoplasms; Drug Interactions; Female; Fluorouracil; Galactosamine; I

1980
Inhibition of aberrant crypt growth by non-steroidal anti-inflammatory agents and differentiation agents in the rat colon.
    International journal of cancer, 1995, Feb-08, Volume: 60, Issue:4

    Topics: Acetaminophen; Adenoma; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti

1995
Nonsteroidal antiinflammatory drugs and colorectal cancer.
    Cancer, 1994, Oct-01, Volume: 74, Issue:7

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Colonic N

1994
Aspirin use and risk of fatal cancer.
    Cancer research, 1993, Mar-15, Volume: 53, Issue:6

    Topics: Acetaminophen; Aspirin; Colonic Neoplasms; Digestive System Neoplasms; Esophageal Neoplasms; Female;

1993
Prospective comparison of gastric emptying after laparoscopic-aided colectomy versus open colectomy.
    The American surgeon, 1996, Volume: 62, Issue:7

    Topics: Acetaminophen; Colectomy; Colonic Diseases; Colonic Neoplasms; Diverticulum, Colon; Gastric Emptying

1996
Cell-type-specific activation of c-Jun N-terminal kinase by salicylates.
    Journal of cellular physiology, 1999, Volume: 179, Issue:1

    Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Ca

1999
Laparoscopic-assisted colonoscopic polypectomy: the Texas Endosurgery Institute experience.
    Diseases of the colon and rectum, 2000, Volume: 43, Issue:9

    Topics: Acetaminophen; Adenoma, Villous; Aged; Analgesics, Non-Narcotic; Colonic Neoplasms; Colonic Polyps;

2000
Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancer.
    Pharmacotherapy, 2002, Volume: 22, Issue:3

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Breast

2002
Protective effect of acetaminophen against colon cancer initiation effects of 3,2'-dimethyl-4-aminobiphenyl in rats.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2002, Volume: 11, Issue:1

    Topics: Acetaminophen; Aminobiphenyl Compounds; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neopl

2002
Aspirin use and reduced risk of fatal colon cancer.
    The New England journal of medicine, 1992, May-07, Volume: 326, Issue:19

    Topics: Acetaminophen; Adult; Aspirin; Colonic Neoplasms; Humans

1992
Aspirin use and reduced risk of fatal colon cancer.
    The New England journal of medicine, 1991, Dec-05, Volume: 325, Issue:23

    Topics: Acetaminophen; Adult; Aspirin; Cohort Studies; Colonic Neoplasms; Female; Humans; Male; Middle Aged;

1991
An antigen present in rat adenocarcinoma and normal colon non-epithelial stroma is a novel Forssman-like glycolipid based on isoglobotetraosylceramide.
    Biochimica et biophysica acta, 1986, Sep-12, Volume: 878, Issue:2

    Topics: Acetaminophen; Adenocarcinoma; Animals; Antigens, Heterophile; Antigens, Neoplasm; Chromatography, G

1986