acetaminophen has been researched along with Cancer Pain in 15 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Cancer Pain: Pain that may be caused by or related to cellular, tissue, and systemic changes that occur during NEOPLASM growth, tissue invasion, and METASTASIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among patients with cancer pain on strong opioid regime, acetaminophen may not improve pain control, or decrease total opioid use." | 9.69 | Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial. ( Castellano, J; González, A; Leiva-Vásquez, O; Letelier, LM; Pérez-Cruz, PE; Rojas, L; Viviani, P, 2023) |
| "Morphine is the first-choice drug for moderate-to-severe cancer pain, nevertheless, some patients do not achieve adequate pain relief or exhibit intolerable side effects." | 9.24 | Assessment of the Analgesic Effect of Magnesium and Morphine in Combination in Patients With Cancer Pain: A Comparative Randomized Double-Blind Study. ( Arruda, GV; Baaklini, LG; Sakata, RK, 2017) |
| "To assess the efficacy of oral paracetamol (acetaminophen) for cancer pain in adults and children, and the adverse events reported during its use in clinical trials." | 8.95 | Oral paracetamol (acetaminophen) for cancer pain. ( Bell, RF; Carr, DB; Derry, S; McIntyre, M; McNicol, ED; Moore, RA; Wee, B; Wiffen, PJ, 2017) |
| "The mainstay of treatment in advanced cancer pain is opioids; however, non-opioid medications such as acetaminophen continue to be included in guidelines despite a lack of clear, convincing evidence for their use." | 7.96 | Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain. ( Quirk, K; Smith, MA, 2020) |
| "Cancer pain is one of the most frequent and relevant symptoms in cancer patients and impacts on patient's quality of life." | 7.11 | Randomized double-blind controlled trial to assess the efficacy of intravenous acetaminophen associated with strong opioids in the treatment of acute pain in adult cancer patients: study protocol. ( Castellano, J; Gonzalez, A; Leiva, O; Letelier, LM; Perez-Cruz, P; Rojas, L; Viviani, P, 2022) |
| "Tramadol is an opioid analgesic licensed for use in moderate to severe pain." | 6.55 | Tramadol with or without paracetamol (acetaminophen) for cancer pain. ( Derry, S; Moore, RA; Wiffen, PJ, 2017) |
| "Among patients with cancer pain on strong opioid regime, acetaminophen may not improve pain control, or decrease total opioid use." | 5.69 | Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial. ( Castellano, J; González, A; Leiva-Vásquez, O; Letelier, LM; Pérez-Cruz, PE; Rojas, L; Viviani, P, 2023) |
| "Morphine is the first-choice drug for moderate-to-severe cancer pain, nevertheless, some patients do not achieve adequate pain relief or exhibit intolerable side effects." | 5.24 | Assessment of the Analgesic Effect of Magnesium and Morphine in Combination in Patients With Cancer Pain: A Comparative Randomized Double-Blind Study. ( Arruda, GV; Baaklini, LG; Sakata, RK, 2017) |
| "To assess the efficacy of oral paracetamol (acetaminophen) for cancer pain in adults and children, and the adverse events reported during its use in clinical trials." | 4.95 | Oral paracetamol (acetaminophen) for cancer pain. ( Bell, RF; Carr, DB; Derry, S; McIntyre, M; McNicol, ED; Moore, RA; Wee, B; Wiffen, PJ, 2017) |
| "The mainstay of treatment in advanced cancer pain is opioids; however, non-opioid medications such as acetaminophen continue to be included in guidelines despite a lack of clear, convincing evidence for their use." | 3.96 | Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain. ( Quirk, K; Smith, MA, 2020) |
| " Group 1 was consisted of 353 patients whose basal cancer pain of intensity 4-7 NRS was treated weak opiates (basal analgetic- fixed combination of tramadol/paracetamol (37." | 3.85 | Characteristics and Treatment of Breakthrought Pain (BTcP) in Palliative Care. ( Husic, S; Imamovic, S; Matic, S; Sukalo, A, 2017) |
| "Cancer pain is one of the most frequent and relevant symptoms in cancer patients and impacts on patient's quality of life." | 3.11 | Randomized double-blind controlled trial to assess the efficacy of intravenous acetaminophen associated with strong opioids in the treatment of acute pain in adult cancer patients: study protocol. ( Castellano, J; Gonzalez, A; Leiva, O; Letelier, LM; Perez-Cruz, P; Rojas, L; Viviani, P, 2022) |
| "Tramadol is an opioid analgesic licensed for use in moderate to severe pain." | 2.55 | Tramadol with or without paracetamol (acetaminophen) for cancer pain. ( Derry, S; Moore, RA; Wiffen, PJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 5 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Leiva, O | 1 |
| Castellano, J | 2 |
| Letelier, LM | 2 |
| Rojas, L | 2 |
| Viviani, P | 2 |
| Gonzalez, A | 2 |
| Perez-Cruz, P | 1 |
| Leiva-Vásquez, O | 1 |
| Pérez-Cruz, PE | 2 |
| Chapman, EJ | 1 |
| Edwards, Z | 1 |
| Boland, JW | 1 |
| Maddocks, M | 1 |
| Fettes, L | 1 |
| Malia, C | 1 |
| Mulvey, MR | 1 |
| Bennett, MI | 1 |
| Quirk, K | 1 |
| Smith, MA | 1 |
| Tlijani, M | 1 |
| Sayadi, M | 1 |
| Zribi, K | 1 |
| Jbeli, F | 1 |
| Zaied, S | 1 |
| Daldoul, A | 1 |
| Ben Salah, Y | 1 |
| Saidani, Z | 1 |
| Cherif, A | 1 |
| Wiffen, PJ | 3 |
| Derry, S | 3 |
| Moore, RA | 3 |
| Corsi, O | 1 |
| Wee, B | 2 |
| Bell, RF | 2 |
| McNicol, ED | 1 |
| Carr, DB | 1 |
| McIntyre, M | 1 |
| Husic, S | 1 |
| Imamovic, S | 1 |
| Matic, S | 1 |
| Sukalo, A | 1 |
| Fredheim, OMS | 1 |
| Niki, K | 1 |
| Okamoto, Y | 1 |
| Nakajima, S | 1 |
| Uejima, E | 1 |
| Baaklini, LG | 1 |
| Arruda, GV | 1 |
| Sakata, RK | 1 |
| Nikles, J | 1 |
| Mitchell, GK | 1 |
| Hardy, J | 1 |
| Senior, H | 1 |
| Carmont, SA | 1 |
| Schluter, PJ | 1 |
| Vora, R | 1 |
| Currow, D | 1 |
| Yelland, M | 1 |
| Barton, MK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Double-blind Controlled Study to Assess the Efficacy of Intravenous Acetaminophen Associated With Strong Opioids in the Management of Acute Pain in Adult Cancer Patients[NCT04779567] | Phase 4 | 112 participants (Actual) | Interventional | 2019-06-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for acetaminophen and Cancer Pain
| Article | Year |
|---|---|
Practice review: Evidence-based and effective management of pain in patients with advanced cancer.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cance | 2020 |
Tramadol with or without paracetamol (acetaminophen) for cancer pain.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Drug Therapy, | 2017 |
Opioids for cancer pain - an overview of Cochrane reviews.
Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; C | 2017 |
Oral paracetamol (acetaminophen) for cancer pain.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2017 |
[Pain management for cancer patients in drug-assisted rehabilitation].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2018 |
3 trials available for acetaminophen and Cancer Pain
| Article | Year |
|---|---|
Randomized double-blind controlled trial to assess the efficacy of intravenous acetaminophen associated with strong opioids in the treatment of acute pain in adult cancer patients: study protocol.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Analgesics, Opioid; Cancer Pain; Humans; Neoplasms; Qu | 2022 |
Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Double-Blind M | 2023 |
Assessment of the Analgesic Effect of Magnesium and Morphine in Combination in Patients With Cancer Pain: A Comparative Randomized Double-Blind Study.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Analgesics, | 2017 |
7 other studies available for acetaminophen and Cancer Pain
| Article | Year |
|---|---|
Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Humans; Neoplasms; | 2020 |
[Pain management in cancer patients in a Tunisian hospital].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; F | 2021 |
Is it useful to add acetaminophen to high-potency opioids in cancer-related pain?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Databases, Factual; Drug T | 2017 |
Characteristics and Treatment of Breakthrought Pain (BTcP) in Palliative Care.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2017 |
The analgesic effect of rescue administration of intravenous acetaminophen in cancer patients may be associated with sex and opioid dose, and the effect would appear to patients administered under 45 mg/day opioid (oral morphine equivalents).
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioi | 2018 |
Single-patient multiple crossover studies to determine the effectiveness of paracetamol in relieving pain suffered by patients with advanced cancer taking regular opioids: A pilot study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Cross-Over Studies; | 2016 |
First-line low-dose morphine is better for the control of moderate cancer pain than weaker opioids.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Humans; Morphine; Pain Man | 2016 |