Page last updated: 2024-10-21

acetaminophen and Brain Injuries, Traumatic

acetaminophen has been researched along with Brain Injuries, Traumatic in 6 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Brain Injuries, Traumatic: A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain.

Research Excerpts

ExcerptRelevanceReference
"A clinical pharmacokinetic study in adult patients with TBI was performed as a sub-study to a prospective, phase 2B, randomized placebo-controlled study (PARITY)."2.87Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. ( Gowardman, J; Lipman, J; Myburgh, J; Parker, SL; Roberts, JA; Saxena, M, 2018)
" Our aim was to translate a recently published comprehensive CNS physiologically-based pharmacokinetic (PBPK) model from rat to human, and to predict drug concentration-time profiles in multiple CNS compartments on available human data of four drugs (acetaminophen, oxycodone, morphine and phenytoin)."1.48Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach. ( Beukers, MW; Danhof, M; de Lange, ECM; Huntjens, DR; Kokki, H; Kokki, M; Krauwinkel, W; Proost, JH; Välitalo, PA; van Hasselt, JGC; Vermeulen, A; Wong, YC; Yamamoto, Y, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Karpińska, G1
Dobrowolski, JC1
Yinda, CK1
Rector, A1
Zeller, M1
Conceição-Neto, N1
Heylen, E1
Maes, P1
Ghogomu, SM1
Van Ranst, M1
Matthijnssens, J1
Arthanari, SK1
Vanitha, J1
Ganesh, M1
Venkateshwaran, K1
de Lama Caro-Patón, G1
García-Salido, A1
Iglesias-Bouzas, MI1
Guillén, M1
Cañedo-Villaroya, E1
Martínez-Romera, I1
Serrano-González, A1
Casado-Flores, J1
Gale, P2
Chen, X2
Li, H1
Lucero-Prisno, DE1
Abdullah, AS1
Huang, J1
Laurence, C1
Liang, X1
Ma, Z1
Mao, Z1
Ren, R1
Wu, S1
Wang, N1
Wang, P2
Wang, T1
Yan, H1
Zou, Y1
Olsen, KM1
Gabler, NK1
Rademacher, CJ1
Schwartz, KJ1
Schweer, WP1
Gourley, GG1
Patience, JF1
Rauch, JC1
Stokes, RS1
Shike, DW1
Luebbe, KM1
Stalker, LA1
Klopfenstein, TJ1
Funston, RN1
Unger, PA1
Lighaam, LC1
Vermeulen, E1
Kruithof, S1
Makuch, M1
Culver, EL1
van Bruggen, R1
Remmerswaal, EBM1
Ten Berge, IJM1
Emmens, RW1
Niessen, HWM1
Barnes, E1
Wolbink, GJ1
van Ham, SM1
Rispens, T1
Liang, JX1
Lin, J1
Liu, J1
Wang, X1
Zhang, T1
Li, J1
Wu, Y2
Venier, M1
Salamova, A1
Gonçales, VR1
Lian, J1
Gautam, S1
Tilley, RD1
Gooding, JJ1
Kandel, YR1
Bradley, CA1
Chilvers, MI1
Mathew, FM1
Tenuta, AU1
Smith, DL1
Wise, KA1
Mueller, DS1
Lu, N1
Lu, M1
Liu, P1
Xu, H1
Qiu, X1
Hu, S1
Bai, S1
Wu, J1
Xue, S1
Dai, X1
Dharmage, SC1
Abramson, MJ1
Erbas, B1
Bennett, CM1
Svanes, C1
Hui, J1
Axelrad, C1
Lowe, AJ1
Lodge, CJ1
Hoshi, M1
Osawa, Y1
Nakamoto, K1
Morita, N1
Yamamoto, Y2
Ando, T1
Tashita, C1
Nabeshima, T1
Saito, K1
Gianesello, L1
Del Prete, D1
Ceol, M1
Priante, G1
Calò, LA1
Anglani, F1
Vekaria, HJ1
Hubbard, WB1
Scholpa, NE1
Spry, ML1
Gooch, JL1
Prince, SJ1
Schnellmann, RG1
Sullivan, PG1
Zhang, Q1
Hu, R1
Gu, Z1
Zhang, M1
Zhang, Z1
Peng, Y1
Feng, L1
Li, X3
Zhao, C1
Sarfaraz, K1
Gao, L1
Wang, H1
Wan, C1
Leng, J1
Yang, P1
Gao, X1
Gao, J1
Emam, HE1
Saad, NM1
Abdallah, AEM1
Ahmed, HB1
Palombo, M1
Ianus, A1
Guerreri, M1
Nunes, D1
Alexander, DC1
Shemesh, N1
Zhang, H1
Xiong, Q1
Liu, YS1
Hu, LX1
Shi, ZQ1
Ying, GG1
Chen, R1
Hong, X1
Yan, S1
Zha, J1
Gu, H1
Zhong, Q1
Zeng, Y1
Zhang, S1
Bu, Y1
Farghali, M1
Mayumi, M1
Syo, K1
Satoshi, A1
Seiichi, Y1
Takashima, S1
Ono, H1
Ap, Y1
Yamashiro, T1
Ahmed, MM1
Kotb, S1
Iwasaki, M1
Ihara, I1
Umetsu, K1
Hu, B1
Wang, Y2
Quan, J1
Huang, K1
Gu, X1
Zhu, J1
Yan, Y1
Wu, P1
Yang, L1
Zhao, J1
Koók, L1
Nemestóthy, N1
Bélafi-Bakó, K1
Bakonyi, P1
Luo, X1
Zhang, F1
Li, Q1
Xia, Q1
Li, Z1
Ye, W1
Li, S1
Ge, C1
Zakkula, A1
Pulipati, S1
Dittakavi, S1
Bestha, RM1
Zainuddin, M1
Trivedi, RK1
Mullangi, R1
Lo, GH1
Lin, CW1
Tai, CM1
Perng, DS1
Chen, IL1
Yeh, JH1
Lin, HC1
Rocha, GS1
Silva, MKL1
Cesarino, I1
Hazzaa, SM1
Abdelaziz, SAM1
Abd Eldaim, MA1
Abdel-Daim, MM1
Elgarawany, GE1
Larsson, P1
Ljuslinder, I1
Öhlund, D1
Myte, R1
Löfgren-Burström, A1
Zingmark, C1
Ling, A1
Edin, S1
Palmqvist, R1
Murthi, P1
Rajaraman, G1
Erwich, JJHM1
Dimitriadis, E1
Yoon, HG1
Oh, D1
Ahn, YC1
Noh, JM1
Pyo, H1
Cho, WK1
Song, YM1
Park, M1
Hwang, NY1
Sun, JM1
Kim, HK1
Zo, JI1
Shim, YM1
Persano, A1
Quaranta, F1
Taurino, A1
Siciliano, PA1
Iannacci, J1
Malekbala, MR1
Soltani, S1
Abdul Rashid, S1
Abdullah, LC1
Rashid, U1
Nehdi, IA1
Choong, TSY1
Teo, SH1
Xu, P1
Yan, F1
Zhao, Y1
Sun, S1
Ying, L1
Quinzi, V1
Caruso, S1
Mummolo, S1
Nota, A1
Angelone, AM1
Mattei, A1
Gatto, R1
Marzo, G1
Xin, W1
Severino, J1
Venkert, A1
Yu, H1
Knorr, D1
Yang, JM1
Carlson, L1
Hicks, R1
De Rosa, I1
Beckmann, NA1
Bitsch, RG1
Schonhoff, M1
Siebenrock, KA1
Schwarze, M1
Jaeger, S1
Lewis, SR1
Baker, PE1
Andrews, PJ1
Cheng, A1
Deol, K1
Hammond, N1
Saxena, M2
Välitalo, PA1
Wong, YC1
Huntjens, DR1
Proost, JH1
Vermeulen, A1
Krauwinkel, W1
Beukers, MW1
Kokki, H1
Kokki, M1
Danhof, M1
van Hasselt, JGC1
de Lange, ECM1
Safari, L1
Patrick, JD1
Parker, SL1
Gowardman, J1
Lipman, J1
Myburgh, J1
Roberts, JA1
Cervinski, MA1
Jannetto, PJ1

Reviews

2 reviews available for acetaminophen and Brain Injuries, Traumatic

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
Interventions to reduce body temperature to 35 ⁰C to 37 ⁰C in adults and children with traumatic brain injury.
    The Cochrane database of systematic reviews, 2020, 10-31, Volume: 10

    Topics: Acetaminophen; Adult; Antipyretics; Bias; Body Temperature; Brain Injuries, Traumatic; Humans; Hypot

2020

Trials

2 trials available for acetaminophen and Brain Injuries, Traumatic

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury.
    Journal of critical care, 2018, Volume: 47

    Topics: Acetaminophen; Adult; Antipyretics; Area Under Curve; Brain Injuries, Traumatic; Critical Illness; D

2018

Other Studies

3 other studies available for acetaminophen and Brain Injuries, Traumatic

ArticleYear
Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jan-15, Volume: 112

    Topics: Acetaminophen; Animals; Biological Transport; Brain; Brain Injuries, Traumatic; Central Nervous Syst

2018
Complex analyses on clinical information systems using restricted natural language querying to resolve time-event dependencies.
    Journal of biomedical informatics, 2018, Volume: 82

    Topics: Acetaminophen; Algorithms; Body Temperature; Brain Injuries, Traumatic; Data Collection; Data Scienc

2018
A Question of Opioid Diversion or Compliance.
    Clinical chemistry, 2019, Volume: 65, Issue:2

    Topics: Acetaminophen; Analgesics, Opioid; Brain Injuries, Traumatic; Chromatography, High Pressure Liquid;

2019