Page last updated: 2024-10-22

acetaminophen and Benign Supratentorial Neoplasms

acetaminophen has been researched along with Benign Supratentorial Neoplasms in 3 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"Postoperative pain was assessed in the fully awake patient after extubation (hour 0) and at 1, 2, 4, 8, and 24 hours using a visual analog scale (VAS)."2.70Postoperative pain management after supratentorial craniotomy. ( Grenier, B; Maurette, P; Mesli, A; Sesay, M; Siao, D; Verchère, E, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Rajkiran, R1
Soni, SL1
Jangra, K1
Bhagat, H1
Singh, A2
Panda, NB1
Kaloria, N1
Sivakumar, W1
Jensen, M1
Martinez, J1
Tanana, M1
Duncan, N1
Hoesch, R1
Riva-Cambrin, JK1
Kilburg, C1
Ansari, S1
House, PA1
Verchère, E1
Grenier, B1
Mesli, A1
Siao, D1
Sesay, M1
Maurette, P1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT01948505]Phase 4210 participants (Actual)Interventional2013-08-31Completed
The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in[NCT02852382]Phase 245 participants (Actual)Interventional2014-04-30Completed
Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy[NCT05763836]Phase 4102 participants (Anticipated)Interventional2022-11-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Narcotic Requirement After Surgery

The primary efficacy end point was narcotic consumption during the first 48 hours after craniotomy. Opioid usage was calculated by converting the amount of the narcotics taken by the patient into oral morphine equivalents (ME), which were totaled for each postoperative day. At 48 hours after surgery, patients who received IV acetaminophen in addition to our standardized pain protocol did not have a statistically significantly lower mean narcotic requirement, measured in ME, when compared with those in the placebo group. (NCT01948505)
Timeframe: 48 hours

InterventionMorphine Equivalents (Mean)
Experimental Group123.5
Placebo Group134.2

Trials

3 trials available for acetaminophen and Benign Supratentorial Neoplasms

ArticleYear
Diclofenac Is Superior to Paracetamol in Postoperative Pain Scores and Analgesic Consumption in Supratentorial Craniotomy With No Difference in Platelet and Clot Function: A Prospective Randomized Controlled Trial.
    Journal of neurosurgical anesthesiology, 2022, Jul-01, Volume: 34, Issue:3

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Crani

2022
Intravenous acetaminophen for postoperative supratentorial craniotomy pain: a prospective, randomized, double-blinded, placebo-controlled trial.
    Journal of neurosurgery, 2018, 04-20, Volume: 130, Issue:3

    Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniotomy

2018
Postoperative pain management after supratentorial craniotomy.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe

2002
Postoperative pain management after supratentorial craniotomy.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe

2002
Postoperative pain management after supratentorial craniotomy.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe

2002
Postoperative pain management after supratentorial craniotomy.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe

2002