acetaminophen has been researched along with Benign Neoplasms in 96 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among patients with cancer pain on strong opioid regime, acetaminophen may not improve pain control, or decrease total opioid use." | 9.69 | Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial. ( Castellano, J; González, A; Leiva-Vásquez, O; Letelier, LM; Pérez-Cruz, PE; Rojas, L; Viviani, P, 2023) |
| "The present study aimed to examine the effectiveness of intravenous administration of paracetamol added to morphine in the control of cancer pain and its possible contribution as reduction of opioid consumption and opioid-related side effects." | 9.14 | Effect of intravenous administration of paracetamol on morphine consumption in cancer pain control. ( Aydinli, I; Keskinbora, K; Pekel, AF; Salihoglu, T; Sonsuz, A; Tasmacioglu, B, 2009) |
| "Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions." | 9.13 | A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008) |
| "To determine whether adding regular acetaminophen (paracetamol) could improve pain and well-being in people with advanced cancer and pain despite strong opioids." | 9.11 | Acetaminophen (paracetamol) improves pain and well-being in people with advanced cancer already receiving a strong opioid regimen: a randomized, double-blind, placebo-controlled cross-over trial. ( Pillai, A; Stockler, M; Vardy, J; Warr, D, 2004) |
| "To determine the efficacy and safety of codeine used alone or in combination with paracetamol for relieving cancer pain." | 8.90 | Codeine, alone and with paracetamol (acetaminophen), for cancer pain. ( Bell, RF; Derry, S; Jackson, KC; Strassels, S; Straube, C; Straube, S; Wiffen, PJ, 2014) |
| "The mainstay of treatment in advanced cancer pain is opioids; however, non-opioid medications such as acetaminophen continue to be included in guidelines despite a lack of clear, convincing evidence for their use." | 7.96 | Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain. ( Quirk, K; Smith, MA, 2020) |
| "Tramadol/acetaminophen might be efficacious and safe in the treatment of breakthrough pain in cancer." | 7.76 | Efficacy and safety of tramadol/acetaminophen in the treatment of breakthrough pain in cancer patients. ( Chang, CS; Chung, CY; Ho, ML; Hsu, NC; Lin, HY; Wang, CC, 2010) |
| "Morphine and other opioids are the mainstay of cancer pain management, yet considerable fears surrounding them present barriers to pain control." | 7.74 | Opioid analgesics for cancer pain: symptom control for the living or comfort for the dying? A qualitative study to investigate the factors influencing the decision to accept morphine for pain caused by cancer. ( Gooberman-Hill, R; Hanks, GW; Reid, CM, 2008) |
| "Cancer pain is one of the most frequent and relevant symptoms in cancer patients and impacts on patient's quality of life." | 7.11 | Randomized double-blind controlled trial to assess the efficacy of intravenous acetaminophen associated with strong opioids in the treatment of acute pain in adult cancer patients: study protocol. ( Castellano, J; Gonzalez, A; Leiva, O; Letelier, LM; Perez-Cruz, P; Rojas, L; Viviani, P, 2022) |
| " Large patient-to-patient variations in pharmacokinetic parameters occurred, although intraindividual variability was limited." | 6.71 | Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients. ( Bressolle, F; Caumette, L; Culine, S; Garcia, F; Pinguet, F; Poujol, S; Solassol, I, 2005) |
| "Among patients with cancer pain on strong opioid regime, acetaminophen may not improve pain control, or decrease total opioid use." | 5.69 | Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial. ( Castellano, J; González, A; Leiva-Vásquez, O; Letelier, LM; Pérez-Cruz, PE; Rojas, L; Viviani, P, 2023) |
| "The present study aimed to examine the effectiveness of intravenous administration of paracetamol added to morphine in the control of cancer pain and its possible contribution as reduction of opioid consumption and opioid-related side effects." | 5.14 | Effect of intravenous administration of paracetamol on morphine consumption in cancer pain control. ( Aydinli, I; Keskinbora, K; Pekel, AF; Salihoglu, T; Sonsuz, A; Tasmacioglu, B, 2009) |
| " In this scenario, the association with acetaminophen did not improve pain control or reduce the time to achieve an equianalgesic dose of methadone." | 5.14 | Early switching from morphine to methadone is not improved by acetaminophen in the analgesia of oncologic patients: a prospective, randomized, double-blind, placebo-controlled study. ( Cubero, DI; del Giglio, A, 2010) |
| "The adjunctive use of paracetamol (acetaminophen) with strong opioids has become entrenched practice in palliative care pain management, despite little evidence to support its use." | 5.14 | Lack of benefit from paracetamol (acetaminophen) for palliative cancer patients requiring high-dose strong opioids: a randomized, double-blind, placebo-controlled, crossover trial. ( Charles, M; Israel, FJ; Parker, G; Reymond, L, 2010) |
| "Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions." | 5.13 | A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008) |
| "To determine whether adding regular acetaminophen (paracetamol) could improve pain and well-being in people with advanced cancer and pain despite strong opioids." | 5.11 | Acetaminophen (paracetamol) improves pain and well-being in people with advanced cancer already receiving a strong opioid regimen: a randomized, double-blind, placebo-controlled cross-over trial. ( Pillai, A; Stockler, M; Vardy, J; Warr, D, 2004) |
| "To determine the efficacy and safety of codeine used alone or in combination with paracetamol for relieving cancer pain." | 4.90 | Codeine, alone and with paracetamol (acetaminophen), for cancer pain. ( Bell, RF; Derry, S; Jackson, KC; Strassels, S; Straube, C; Straube, S; Wiffen, PJ, 2014) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "The mainstay of treatment in advanced cancer pain is opioids; however, non-opioid medications such as acetaminophen continue to be included in guidelines despite a lack of clear, convincing evidence for their use." | 3.96 | Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain. ( Quirk, K; Smith, MA, 2020) |
| " Group 1 was consisted of 353 patients whose basal cancer pain of intensity 4-7 NRS was treated weak opiates (basal analgetic- fixed combination of tramadol/paracetamol (37." | 3.85 | Characteristics and Treatment of Breakthrought Pain (BTcP) in Palliative Care. ( Husic, S; Imamovic, S; Matic, S; Sukalo, A, 2017) |
| "Tramadol/acetaminophen might be efficacious and safe in the treatment of breakthrough pain in cancer." | 3.76 | Efficacy and safety of tramadol/acetaminophen in the treatment of breakthrough pain in cancer patients. ( Chang, CS; Chung, CY; Ho, ML; Hsu, NC; Lin, HY; Wang, CC, 2010) |
| "Morphine and other opioids are the mainstay of cancer pain management, yet considerable fears surrounding them present barriers to pain control." | 3.74 | Opioid analgesics for cancer pain: symptom control for the living or comfort for the dying? A qualitative study to investigate the factors influencing the decision to accept morphine for pain caused by cancer. ( Gooberman-Hill, R; Hanks, GW; Reid, CM, 2008) |
| " Attention should be paid to the appearance of side-effects of morphine, the circulation of pain graduation tables and the evaluation of anxiety in this category of patient." | 3.69 | [Treatment of pain and anxiety in terminal oncologic patients in the Castilla-La Mancha community]. ( Calles Gato, MD; Hernández Moreno, J; López de Castro, F; Muñoz González, F; Sánchez del Viso, Y; Sánchez Muñoz, C, 1995) |
| "Cancer pain is one of the most frequent and relevant symptoms in cancer patients and impacts on patient's quality of life." | 3.11 | Randomized double-blind controlled trial to assess the efficacy of intravenous acetaminophen associated with strong opioids in the treatment of acute pain in adult cancer patients: study protocol. ( Castellano, J; Gonzalez, A; Leiva, O; Letelier, LM; Perez-Cruz, P; Rojas, L; Viviani, P, 2022) |
| "Eligible patients had cancer, pain ≥4/10 on a 0-10 numerical rating scale, required at least step 1 (paracetamol) of the WHO ladder and were randomised to the control arm (weak opioid, step 2 of the WHO ladder) or the experimental arm (strong opioid, step 3)." | 3.11 | An international, open-label, randomised trial comparing a two-step approach versus the standard three-step approach of the WHO analgesic ladder in patients with cancer. ( Allende, S; Caraceni, A; Dierberger, K; Fallon, M; Gordon, D; Grant, L; Hall, PS; Kaasa, S; Laird, BJA; Lee, R; Leng, M; McWillams, K; Murray, GD; Norris, L; Reid, C; Sabar, R; Sande, TA; Verastegui, E, 2022) |
| "Thirty-four incurable cancer patients with well controlled pain (NRSB4), treated by specialised palliative home care teams, with ongoing medication with the strong opioid paracetamol combination was recruited to this prospective clinical study." | 2.73 | Analgesic effect of paracetamol on cancer related pain in concurrent strong opioid therapy. A prospective clinical study. ( Axelsson, B; Stellborn, P; Ström, G, 2008) |
| " In both groups, if pain intensity was rated as > 3 on the VAS at week 1 or 2, the dosage was doubled." | 2.73 | Codeine/acetaminophen and hydrocodone/acetaminophen combination tablets for the management of chronic cancer pain in adults: a 23-day, prospective, double-blind, randomized, parallel-group study. ( Angel, AM; Castillo, JM; Del Pilar Castillo, M; Nuñez, PD; Ortiz, Y; Restrepo, JM; Rodriguez, JM; Rodriguez, MF; Rodriguez, RF, 2007) |
| "For 3 cancer types, renal cell, liver, and some forms of lymphohematopoietic, some studies suggest an increased risk; however, multiple factors unique to acetaminophen need to be considered to determine if these results are real and clinically meaningful." | 2.72 | A systematic assessment of the epidemiologic literature regarding an association between acetaminophen exposure and cancer. ( Atillasoy, E; Berlin, JA; Eichenbaum, G; Hermanowski-Vosatka, A; Parikh-Das, AM; Ryan, PB; Salonga, R; Schuemie, M; Weinstein, R, 2021) |
| "Pain was mostly therapy associated." | 2.72 | Paediatric cancer pain management using the WHO analgesic ladder--results of a prospective analysis from 2265 treatment days during a quality improvement study. ( Andler, W; Hasan, C; Jorch, N; Michel, E; Smale, H; Zernikow, B, 2006) |
| " Large patient-to-patient variations in pharmacokinetic parameters occurred, although intraindividual variability was limited." | 2.71 | Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients. ( Bressolle, F; Caumette, L; Culine, S; Garcia, F; Pinguet, F; Poujol, S; Solassol, I, 2005) |
| "Although it is necessary to treat the cause of fever, if possible, symptomatic fever management is also important." | 2.70 | Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol. ( Korístek, Z; Mayer, J; Oborilová, A; Pospísil, Z, 2002) |
| "Chronic hepatitis C was a frequent complication in patients treated for malignancy until the introduction of anti-HCV screening tests for blood donors." | 2.69 | Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies. ( Bortolotti, F; Brugiolo, A; Cesaro, S; Cusinato, R; Guido, M; Masiero, L; Petris, MG; Rossetti, F; Zanesco, L, 2000) |
| "For all but several forms of cancer, there is no suggestion that persons who have taken acetaminophen are at altered risk, even persons who have consumed a large quantity of the drug or those who have taken it for an extended duration." | 2.53 | Use of acetaminophen in relation to the occurrence of cancer: a review of epidemiologic studies. ( Weiss, NS, 2016) |
| "Refractory cancer pain that does not respond to standard opioid and/or co-analgesic therapy occurs in 10-20 % of patients." | 2.52 | Pharmacological options for the management of refractory cancer pain-what is the evidence? ( Afsharimani, B; Good, P; Hardy, J; Kindl, K, 2015) |
| "Quality pain management for cancer survivors is complicated by the fact that cancer-related pain can be due to the tumor, surgery, radiation, and/or chemotherapy." | 2.50 | Understanding the cancer pain experience. ( Schreiber, JA, 2014) |
| "The pain experienced by cancer patients can be managed in 70-90% of cases by the World Health Organisation protocol for cancer pain." | 2.47 | [Solutions for the clinical problems of analgesics for cancer pain treatment in Japan]. ( Kokubun, H; Matoba, M; Yago, K; Yamada, Y, 2011) |
| "Malignancy is an uncommon cause of ALF, and thus imaging studies may not be useful in this setting, but liver biopsy may be beneficial in selected cases." | 2.44 | Epidemiology of acute liver failure. ( Khashab, M; Kwo, PY; Tector, AJ, 2007) |
| "To assess the effects of NSAIDs, alone or combined with opioids, for the treatment of cancer pain." | 2.43 | NSAIDS or paracetamol, alone or combined with opioids, for cancer pain. ( Carr, DB; Goudas, L; Lau, J; McNicol, E; Strassels, SA, 2005) |
| "Accordingly, they have promise as cancer prophylactics, including in combination with agents operating through other mechanisms." | 2.41 | Anticarcinogenicity of monocyclic phenolic compounds. ( Iatropoulos, MJ; Jeffrey, AM; Williams, GM, 2002) |
| "Data on assessment and treatment of spinal cord compression are reviewed." | 2.40 | Management of pain and spinal cord compression in patients with advanced cancer. ACP-ASIM End-of-life Care Consensus Panel. American College of Physicians-American Society of Internal Medicine. ( Abrahm, JL, 1999) |
| "Higher risk of cancer after exposure to paracetamol has not been demonstrated in epidemiological studies, nor has increased risk of cancer been unequivocally documented from animal experiments." | 2.39 | [DNA damages caused by paracetamol]. ( Holme, JA; Hongslo, JK, 1994) |
| "Acetaminophen (APAP) use has been associated with blunted vaccine immune responses." | 1.72 | Impact of acetaminophen on the efficacy of immunotherapy in cancer patients. ( Bessede, A; Cabart, M; Chaibi, A; Chaput, N; Cousin, S; Danlos, FX; Guégan, JP; Italiano, A; Khettab, M; Mahon, FX; Marabelle, A; Nafia, I; Peyraud, F; Rey, C; Roubaud, G; Soria, JC; Spalato, M, 2022) |
| "The effect-size estimates for the cancer outcomes are comparable to those observed for the negative controls." | 1.62 | Quantifying bias in epidemiologic studies evaluating the association between acetaminophen use and cancer. ( Berlin, JA; Ryan, PB; Schuemie, MJ; Weinstein, R, 2021) |
| "Pain is a common and distressing symptom of pediatric cancer, as reported by both children and their parents." | 1.48 | Pain in Children With Cancer: Prevalence, Characteristics, and Parent Management. ( Barwick, M; Campbell, F; Chambers, CT; Fernandez, CV; Irwin, K; Jibb, LA; Nathan, PC; Parker, JA; Stinson, JN; Tutelman, PR; Witteman, HO, 2018) |
| "Pain is a common symptom associated with cancer and its treatment." | 1.39 | Adult cancer pain. ( Abernethy, AP; Anghelescu, DL; Benedetti, C; Buga, S; Cleeland, C; Deleon-Casasola, OA; Dwyer, M; Eilers, JG; Ferrell, B; Green, M; Janjan, NA; Kamdar, MM; Kumar, R; Levy, MH; Lynch, M; McDowell, RM; Moryl, N; Nesbit, SA; Paice, JA; Rabow, MW; Swarm, RA; Syrjala, KL; Urba, SG; Weinstein, SM, 2013) |
| "Pain is among the most frequent and distressing symptoms in terminally-ill cancer and, to date, many patients still experience uncontrolled pain." | 1.37 | [Pain assessment in terminally-ill cancer patients on admission in hospice and its modification after the first three days of care. A monocentric experience]. ( Bordin, F; D'Addario, ME; Di Miele, D; Fava, A; Ferraccioli, A; Lanzetta, G; Ranucci, A; Rozzi, A; Salerno, M; Scirocchi, R; Terzoli, L, 2011) |
| "Among patients without cancer, however, associations of higher oxycodone/acetaminophen doses with benzodiazepine prescriptions, psychogenic pain, alcohol abuse, and HIV/AIDS may portend opioid prescription management problems." | 1.32 | Characterizations of long-term oxycodone/acetaminophen prescriptions in veteran patients. ( Fiore, LD; Gagnon, DR; Hermos, JA; Young, MM, 2004) |
| "The NCCN Cancer Pain Practice Guidelines Panel believes that cancer pain can be well controlled in the vast majority of patients if the algorithms presented are systematically applied, carefully monitored, and tailored to the needs of the individual patient." | 1.31 | NCCN Practice Guidelines for Cancer Pain. ( Benedetti, C; Brock, C; Cleeland, C; Coyle, N; Dubé, JE; Ferrell, B; Hassenbusch, S; Janjan, NA; Lema, MJ; Levy, MH; Loscalzo, MJ; Lynch, M; Muir, C; O'Neill, A; Oakes, L; Payne, R; Syrjala, KL; Urba, S; Weinstein, SM, 2000) |
| " To evaluate the chemopreventive properties of garlic in humans, the effects of chronic administration of an aged garlic extract on the disposition of acetaminophen and metabolites were studied." | 1.29 | The effect of garlic extract on human metabolism of acetaminophen. ( Birt, DD; Grandjean, AC; Gwilt, PR; Lear, CL; Nagel, DL; Ruddon, RW; Tempero, MA, 1994) |
| "Continuous Reaction Time (CRT) was measured in cancer patients receiving peripherally acting analgesics either alone (n = 16) or in combination with opioids (n = 16)." | 1.28 | Reaction time in cancer patients receiving peripherally acting analgesics alone or in combination with opioids. ( Banning, A; Kaiser, F; Sjøgren, P, 1992) |
| "On the other hand, certain tumors require local blockade as in cases with pancreatic or perianal tumors." | 1.27 | [Therapy of pain caused by gastrointestinal tumors]. ( Zenz, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (10.42) | 18.7374 |
| 1990's | 11 (11.46) | 18.2507 |
| 2000's | 34 (35.42) | 29.6817 |
| 2010's | 27 (28.13) | 24.3611 |
| 2020's | 14 (14.58) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Weinstein, R | 2 |
| Parikh-Das, AM | 1 |
| Salonga, R | 1 |
| Schuemie, M | 1 |
| Ryan, PB | 2 |
| Atillasoy, E | 2 |
| Hermanowski-Vosatka, A | 2 |
| Eichenbaum, G | 2 |
| Berlin, JA | 2 |
| vLeiva-Vásquez, O | 1 |
| Pérez-Cruz, P | 2 |
| Bessede, A | 1 |
| Marabelle, A | 1 |
| Guégan, JP | 1 |
| Danlos, FX | 1 |
| Cousin, S | 1 |
| Peyraud, F | 1 |
| Chaput, N | 1 |
| Spalato, M | 1 |
| Roubaud, G | 1 |
| Cabart, M | 1 |
| Khettab, M | 1 |
| Chaibi, A | 1 |
| Rey, C | 1 |
| Nafia, I | 1 |
| Mahon, FX | 1 |
| Soria, JC | 1 |
| Italiano, A | 1 |
| Berraondo, P | 1 |
| Sullivan, RJ | 1 |
| Leiva, O | 1 |
| Castellano, J | 2 |
| Letelier, LM | 2 |
| Rojas, L | 2 |
| Viviani, P | 2 |
| Gonzalez, A | 2 |
| Fallon, M | 1 |
| Dierberger, K | 1 |
| Leng, M | 1 |
| Hall, PS | 1 |
| Allende, S | 1 |
| Sabar, R | 1 |
| Verastegui, E | 1 |
| Gordon, D | 1 |
| Grant, L | 1 |
| Lee, R | 1 |
| McWillams, K | 1 |
| Murray, GD | 1 |
| Norris, L | 1 |
| Reid, C | 1 |
| Sande, TA | 1 |
| Caraceni, A | 2 |
| Kaasa, S | 1 |
| Laird, BJA | 1 |
| Lu, X | 1 |
| Wang, N | 1 |
| Tao, Y | 1 |
| Wang, J | 1 |
| Ji, X | 1 |
| Liu, J | 1 |
| Zhao, W | 1 |
| Zhang, J | 1 |
| Leiva-Vásquez, O | 1 |
| Pérez-Cruz, PE | 2 |
| Jie, X | 1 |
| Wu, M | 1 |
| Yang, H | 1 |
| Wei, W | 1 |
| Chapman, EJ | 1 |
| Edwards, Z | 1 |
| Boland, JW | 1 |
| Maddocks, M | 1 |
| Fettes, L | 1 |
| Malia, C | 1 |
| Mulvey, MR | 1 |
| Bennett, MI | 1 |
| Guengerich, FP | 1 |
| Quirk, K | 1 |
| Smith, MA | 1 |
| Murray, FJ | 1 |
| Monnot, AD | 1 |
| Jacobson-Kram, D | 1 |
| Cohen, SM | 1 |
| Hardisty, JF | 1 |
| Bandara, SB | 1 |
| Kovochich, M | 1 |
| Deore, M | 1 |
| Pitchaiyan, SK | 1 |
| Gelotte, CK | 1 |
| Lai, JCK | 1 |
| Kuffner, E | 1 |
| Unice, KM | 1 |
| Yang, K | 1 |
| Gebremichael, Y | 1 |
| Howell, BA | 1 |
| Zhu, J | 1 |
| Xiong, Y | 1 |
| Zhang, Y | 1 |
| Wen, J | 1 |
| Cai, N | 1 |
| Cheng, K | 1 |
| Liang, H | 1 |
| Zhang, W | 1 |
| Schuemie, MJ | 1 |
| Corsi, O | 1 |
| Tutelman, PR | 1 |
| Chambers, CT | 1 |
| Stinson, JN | 1 |
| Parker, JA | 1 |
| Fernandez, CV | 1 |
| Witteman, HO | 1 |
| Nathan, PC | 1 |
| Barwick, M | 1 |
| Campbell, F | 1 |
| Jibb, LA | 1 |
| Irwin, K | 1 |
| Husic, S | 1 |
| Imamovic, S | 1 |
| Matic, S | 1 |
| Sukalo, A | 1 |
| Nishihara, T | 1 |
| Kuno, S | 1 |
| Nonaka, H | 1 |
| Tabata, S | 1 |
| Saito, N | 1 |
| Fukuda, S | 1 |
| Tomita, M | 1 |
| Sando, S | 1 |
| Soga, T | 1 |
| Swarm, RA | 1 |
| Abernethy, AP | 1 |
| Anghelescu, DL | 1 |
| Benedetti, C | 2 |
| Buga, S | 1 |
| Cleeland, C | 2 |
| Deleon-Casasola, OA | 1 |
| Eilers, JG | 1 |
| Ferrell, B | 2 |
| Green, M | 1 |
| Janjan, NA | 2 |
| Kamdar, MM | 1 |
| Levy, MH | 2 |
| Lynch, M | 2 |
| McDowell, RM | 1 |
| Moryl, N | 1 |
| Nesbit, SA | 1 |
| Paice, JA | 1 |
| Rabow, MW | 1 |
| Syrjala, KL | 2 |
| Urba, SG | 1 |
| Weinstein, SM | 2 |
| Dwyer, M | 1 |
| Kumar, R | 1 |
| Hedén, L | 1 |
| von Essen, L | 1 |
| Ljungman, G | 1 |
| Schreiber, JA | 1 |
| Straube, C | 1 |
| Derry, S | 1 |
| Jackson, KC | 1 |
| Wiffen, PJ | 1 |
| Bell, RF | 1 |
| Strassels, S | 2 |
| Straube, S | 1 |
| Afsharimani, B | 1 |
| Kindl, K | 1 |
| Good, P | 1 |
| Hardy, J | 3 |
| McNicol, ED | 1 |
| Goudas, L | 2 |
| Lau, J | 2 |
| Carr, DB | 2 |
| Nikles, J | 1 |
| Mitchell, GK | 1 |
| Senior, H | 1 |
| Carmont, SA | 1 |
| Schluter, PJ | 1 |
| Vora, R | 1 |
| Currow, D | 1 |
| Yelland, M | 1 |
| Ekşi, S | 1 |
| Ejder, N | 1 |
| Yilmaz, F | 1 |
| Ertürk, A | 1 |
| Sandalli, C | 1 |
| Voillet, V | 1 |
| Besse, P | 1 |
| Liaubet, L | 1 |
| San Cristobal, M | 1 |
| González, I | 1 |
| Weiss, NS | 1 |
| Kennedy, LD | 1 |
| Case, LD | 1 |
| Hurd, DD | 1 |
| Cruz, JM | 1 |
| Pomper, GJ | 1 |
| Tasmacioglu, B | 1 |
| Aydinli, I | 1 |
| Keskinbora, K | 1 |
| Pekel, AF | 1 |
| Salihoglu, T | 1 |
| Sonsuz, A | 1 |
| Cubero, DI | 1 |
| del Giglio, A | 1 |
| Millea, PJ | 1 |
| Bach, SM | 1 |
| Holten, KB | 1 |
| Israel, FJ | 1 |
| Parker, G | 1 |
| Charles, M | 2 |
| Reymond, L | 1 |
| Formby, FT | 1 |
| Marquis, A | 1 |
| Strippoli, MP | 1 |
| Spycher, BD | 1 |
| Rebholz, CE | 1 |
| von der Weid, NX | 1 |
| Kuehni, CE | 1 |
| Ho, ML | 1 |
| Chung, CY | 1 |
| Wang, CC | 1 |
| Lin, HY | 1 |
| Hsu, NC | 1 |
| Chang, CS | 1 |
| Kokubun, H | 1 |
| Matoba, M | 1 |
| Yamada, Y | 1 |
| Yago, K | 1 |
| Walter, RB | 1 |
| Brasky, TM | 1 |
| White, E | 1 |
| Rozzi, A | 1 |
| Scirocchi, R | 1 |
| Fava, A | 1 |
| Bordin, F | 1 |
| D'Addario, ME | 1 |
| Ranucci, A | 1 |
| Lanzetta, G | 1 |
| Di Miele, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Double-blind Controlled Study to Assess the Efficacy of Intravenous Acetaminophen Associated With Strong Opioids in the Management of Acute Pain in Adult Cancer Patients[NCT04779567] | Phase 4 | 112 participants (Actual) | Interventional | 2019-06-10 | Completed | ||
| Swiss Childhood Cancer Survivor Study (SCCSS)[NCT03297034] | 3,626 participants (Anticipated) | Observational [Patient Registry] | 2007-01-01 | Recruiting | |||
| Personalizing Perioperative Morphine Analgesia for Adolescents Undergoing Major Spine Surgeries[NCT01839461] | 137 participants (Actual) | Observational | 2009-07-31 | Completed | |||
| A Randomized, Double-Blinded, Placebo Controlled Trial Using Single Dose Dexmedetomidine In The Treatment Of Pain In Patients Undergoing Cleft Palate Repair[NCT02915042] | Phase 4 | 0 participants (Actual) | Interventional | 2017-12-31 | Withdrawn (stopped due to Recruitment concerns) | ||
| Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery[NCT04031716] | 600 participants (Anticipated) | Interventional | 2018-07-06 | Enrolling by invitation | |||
| Predicting Perioperative Opioid Adverse Effects and Personalizing Analgesia in Children: A Multicenter Pharmacogenetic Study[NCT01495611] | 1,000 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain: A Randomized, Double-Blind Study[NCT00525967] | Phase 2/Phase 3 | 50 participants (Anticipated) | Interventional | 2006-02-28 | Recruiting | ||
| Effect of Massage Therapy on Preoperative Anxiety and Postoperative Pain in Cancer Patients Undergoing Port Implantation[NCT00991770] | Phase 1 | 60 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
31 reviews available for acetaminophen and Benign Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
A systematic assessment of the epidemiologic literature regarding an association between acetaminophen exposure and cancer.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Causality; Humans; Models, Biological; Neoplasms | 2021 |
[Paracetamol as an adjuvant to opioids for cancer pain management].
Topics: Acetaminophen; Analgesics, Opioid; Humans; Morphine; Neoplasms; Pain Management; Quality of Life | 2021 |
Practice review: Evidence-based and effective management of pain in patients with advanced cancer.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cance | 2020 |
Cytochrome P450 2E1 and its roles in disease.
Topics: Acetaminophen; Animals; Carcinogens; Cytochrome P-450 CYP2E1; Ethanol; Humans; Kinetics; Mitochondri | 2020 |
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biotransformation; Carcinogenicity Tests; Cell Tra | 2020 |
The Molecular Mechanisms of Regulating Oxidative Stress-Induced Ferroptosis and Therapeutic Strategy in Tumors.
Topics: Acetaminophen; Antineoplastic Agents; Antioxidants; Apoptosis; Artemisinins; Auranofin; Cell Death; | 2020 |
Understanding the cancer pain experience.
Topics: Acetaminophen; Analgesics; Chronic Pain; Critical Pathways; Fentanyl; Humans; Ketamine; Neoplasms; O | 2014 |
Codeine, alone and with paracetamol (acetaminophen), for cancer pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Drug Therapy, Combinati | 2014 |
Pharmacological options for the management of refractory cancer pain-what is the evidence?
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; B | 2015 |
WITHDRAWN: NSAIDS or paracetamol, alone or combined with opioids, for cancer pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2015 |
Use of acetaminophen in relation to the occurrence of cancer: a review of epidemiologic studies.
Topics: Acetaminophen; Analgesics, Non-Narcotic; California; Humans; Incidence; Neoplasms; Randomized Contro | 2016 |
N-acetylcysteine: multiple clinical applications.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Expectorants; Female; Free Radical Scavengers; Hearing Los | 2009 |
[Solutions for the clinical problems of analgesics for cancer pain treatment in Japan].
Topics: Acetaminophen; Analgesics; Drug Administration Routes; Fentanyl; Humans; Japan; Neoplasms; Oxycodone | 2011 |
The role of paracetamol and nonsteroidal anti-inflammatory drugs in addition to WHO Step III opioids in the control of pain in advanced cancer. A systematic review of the literature.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2012 |
The long and winding road of non steroidal antinflammatory drugs and paracetamol in cancer pain management: a critical review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Neoplasms; | 2013 |
Cancer and chemotherapy-related upper gastrointestinal symptoms: the role of abnormal gastric motor function and its evaluation in cancer patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Antineoplastic Combined Chemotherapy Protocols | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Analgesics for the treatment of pain in children.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2002 |
Anticarcinogenicity of monocyclic phenolic compounds.
Topics: Acetaminophen; Animals; Anticarcinogenic Agents; Butylated Hydroxyanisole; Butylated Hydroxytoluene; | 2002 |
NSAIDS or paracetamol, alone or combined with opioids, for cancer pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2005 |
The 2006 Bernard B. Brodie Award Lecture. Cyp2e1.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cytochrome | 2007 |
[Specific of pharmacotherapy management in back pain among the elderly].
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Back Pain; Chronic Disease; | 2006 |
[Non-opioid analgesics in cancer pain].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Humans; Neoplasms; Pain | 2007 |
Epidemiology of acute liver failure.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug-Related Side Effects and Adverse React | 2007 |
Pharmacologic management of adult cancer pain.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug | 2007 |
A review of the literature on post-operative pain in older cancer patients.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Nefopam; Neoplas | 2007 |
Toxicological considerations for the medicinal chemist.
Topics: Acetaminophen; Amines; Animals; Anticonvulsants; Biotransformation; Chemistry, Pharmaceutical; Drug- | 1981 |
[DNA damages caused by paracetamol].
Topics: Acetaminophen; Animals; DNA Damage; DNA Repair; DNA Replication; Humans; Neoplasms; Neoplasms, Exper | 1994 |
Management of pain and spinal cord compression in patients with advanced cancer. ACP-ASIM End-of-life Care Consensus Panel. American College of Physicians-American Society of Internal Medicine.
Topics: Acetaminophen; Drug Administration Schedule; Humans; Narcotics; Nausea; Neoplasms; Pain; Pain Manage | 1999 |
[Bioactivation of xenobiotics by cytochrome P-448 and its role in the process of carcinogenesis].
Topics: Acetaminophen; Cytochrome P-450 CYP1A2; Cytochromes; Free Radicals; Humans; Hydroxylation; Mixed Fun | 1989 |
20 trials available for acetaminophen and Benign Neoplasms
| Article | Year |
|---|---|
Randomized double-blind controlled trial to assess the efficacy of intravenous acetaminophen associated with strong opioids in the treatment of acute pain in adult cancer patients: study protocol.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Analgesics, Opioid; Cancer Pain; Humans; Neoplasms; Qu | 2022 |
An international, open-label, randomised trial comparing a two-step approach versus the standard three-step approach of the WHO analgesic ladder in patients with cancer.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Neoplasms; Pain; World Health Organization | 2022 |
Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Double-Blind M | 2023 |
Effect of high-dose paracetamol on needle procedures in children with cancer--an RCT.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics, Non-Narcotic; Anesthesia; Child; Child, Preschool | 2014 |
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Do | 2008 |
Effect of intravenous administration of paracetamol on morphine consumption in cancer pain control.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind M | 2009 |
Early switching from morphine to methadone is not improved by acetaminophen in the analgesia of oncologic patients: a prospective, randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2010 |
Lack of benefit from paracetamol (acetaminophen) for palliative cancer patients requiring high-dose strong opioids: a randomized, double-blind, placebo-controlled, crossover trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Studies; Double | 2010 |
Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammato | 2002 |
Is there an additive analgesic effect of paracetamol at step 3? A double-blind randomized controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Delayed | 2003 |
Acetaminophen (paracetamol) improves pain and well-being in people with advanced cancer already receiving a strong opioid regimen: a randomized, double-blind, placebo-controlled cross-over trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Stu | 2004 |
Acetaminophen (paracetamol) improves pain and well-being in people with advanced cancer already receiving a strong opioid regimen: a randomized, double-blind, placebo-controlled cross-over trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Stu | 2004 |
Acetaminophen (paracetamol) improves pain and well-being in people with advanced cancer already receiving a strong opioid regimen: a randomized, double-blind, placebo-controlled cross-over trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Stu | 2004 |
Acetaminophen (paracetamol) improves pain and well-being in people with advanced cancer already receiving a strong opioid regimen: a randomized, double-blind, placebo-controlled cross-over trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Stu | 2004 |
Inter- and intraindividual variabilities in pharmacokinetics of fentanyl after repeated 72-hour transdermal applications in cancer pain patients.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; | 2005 |
Paediatric cancer pain management using the WHO analgesic ladder--results of a prospective analysis from 2265 treatment days during a quality improvement study.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics; Analgesics, Opioid; Antineoplastic Agents; | 2006 |
Codeine/acetaminophen and hydrocodone/acetaminophen combination tablets for the management of chronic cancer pain in adults: a 23-day, prospective, double-blind, randomized, parallel-group study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Comb | 2007 |
Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antineoplastic Agents; Benzoquinones; Child; Ch | 2007 |
Analgesic effect of paracetamol on cancer related pain in concurrent strong opioid therapy. A prospective clinical study.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Administr | 2008 |
Hydrocodone/acetaminophen and tramadol chlorhydrate combination tablets for the management of chronic cancer pain: a double-blind comparative trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combina | 2008 |
Treatment of advanced malignancies with high-dose acetaminophen and N-acetylcysteine rescue.
Topics: Acetaminophen; Acetylcysteine; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Drug Combi | 1996 |
Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies.
Topics: Acetaminophen; Adolescent; Adult; Alanine Transaminase; Alopecia; Asthenia; Chlorpheniramine; DNA, V | 2000 |
A multiinstitutional evaluation of the analgesic efficacy and safety of ketorolac tromethamine, acetaminophen plus codeine, and placebo in cancer pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anti-Inf | 1990 |
45 other studies available for acetaminophen and Benign Neoplasms
| Article | Year |
|---|---|
Impact of acetaminophen on the efficacy of immunotherapy in cancer patients.
Topics: Acetaminophen; Humans; Immunologic Factors; Immunotherapy; Leukocytes, Mononuclear; Neoplasms; T-Lym | 2022 |
The deleterious effect of acetaminophen in cancer immunotherapy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Immunotherapy; Neoplasms | 2022 |
Optimizing phenyl selenide-based BODIPYs as fluorescent probes for diagnosing cancer and drug-induced liver injury
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Fluorescent Dyes; Liver; M | 2022 |
Red-Near-Infrared Fluorescent Probe for Time-Resolved in Vivo Alkaline Phosphatase Detection with the Assistance of a Photoresponsive Nanocontainer.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Benzopyrans; Cell Line, Tumor; Chemical and Drug Induc | 2019 |
Acetaminophen in Patients Receiving Strong Opioids for Cancer Pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Humans; Neoplasms; | 2020 |
Quantifying bias in epidemiologic studies evaluating the association between acetaminophen use and cancer.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Bias; Case-Control Studies; Cohort Studies; Databases, Fact | 2021 |
Is it useful to add acetaminophen to high-potency opioids in cancer-related pain?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Databases, Factual; Drug T | 2017 |
Pain in Children With Cancer: Prevalence, Characteristics, and Parent Management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Caregivers; Child; Female; Humans; Male; Middle Aged | 2018 |
Characteristics and Treatment of Breakthrought Pain (BTcP) in Palliative Care.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2017 |
Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection.
Topics: Acetaminophen; Animals; Antigens, Neoplasm; beta-Galactosidase; Biomarkers, Tumor; Cell Line, Tumor; | 2018 |
Adult cancer pain.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Neoplasms; Pain; | 2013 |
Single-patient multiple crossover studies to determine the effectiveness of paracetamol in relieving pain suffered by patients with advanced cancer taking regular opioids: A pilot study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Cross-Over Studies; | 2016 |
PaCaHa inhibits proliferation of human cancer cells in vitro.
Topics: Acetaminophen; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasms | 2016 |
Handling missing rows in multi-omics data integration: multiple imputation in multiple factor analysis framework.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Data Inter | 2016 |
Guideline update: what's the best approach to acute low back pain?
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cry | 2009 |
Re: lack of benefit from paracetamol (acetaminophen) for palliative cancer patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method | 2010 |
Paracetamol, nonsteroidal anti-inflammatory drugs, and risk of asthma in adult survivors of childhood cancer.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child | 2011 |
Efficacy and safety of tramadol/acetaminophen in the treatment of breakthrough pain in cancer patients.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Drug Therapy, Combination; Female; Humans; Male; Middle Age | 2010 |
Cancer risk associated with long-term use of acetaminophen in the prospective VITamins and lifestyle (VITAL) study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Cohort Studies; Female; Humans; Life Style; Male; Mid | 2011 |
[Pain assessment in terminally-ill cancer patients on admission in hospice and its modification after the first three days of care. A monocentric experience].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Drug Therapy, Combination; | 2011 |
On call. I was very interested in your October 2011 article on aspirin and cancer. You commented that aspirin may help prevent cancer, but I can't take aspirin, even in low doses. I use Tylenol for pain and fever--can it also help against cancer?
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Health Pro | 2011 |
Degradation of vincristine by myeloperoxidase and hypochlorous acid in children with acute lymphoblastic leukemia.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Antineoplastic Agents, Phytogenic; Case-Cont | 2003 |
A population-based cohort study of mortality among adults prescribed paracetamol in Denmark.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Cardiovascular Diseases; Cause of Death; Cerebrovascu | 2003 |
Characterizations of long-term oxycodone/acetaminophen prescriptions in veteran patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Drug Combinatio | 2004 |
Acetaminophen in cancer pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Neoplasms; Pain; Palliative Care | 2005 |
Parenteral iron therapy: a single institution's experience over a 5-year period.
Topics: Acetaminophen; Anemia, Iron-Deficiency; Diphenhydramine; Female; Ferric Compounds; Ferric Oxide, Sac | 2005 |
Opioid analgesics for cancer pain: symptom control for the living or comfort for the dying? A qualitative study to investigate the factors influencing the decision to accept morphine for pain caused by cancer.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Attitude to Death; Codeine; D | 2008 |
The management of the patient with chronic pain due to advanced malignancy.
Topics: Acetaminophen; Analgesics; Aspirin; Chronic Disease; Drug Therapy, Combination; Humans; Narcotics; N | 1982 |
Pharmacological treatment of cancer pain with special reference to the oral use of morphine.
Topics: Acetaminophen; Administration, Oral; Aspirin; Biological Availability; Chronic Disease; Codeine; Hum | 1982 |
[Treatment of pain and anxiety in terminal oncologic patients in the Castilla-La Mancha community].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anxiety; Female; Humans; Ma | 1995 |
Management of cancer pain: adults. Agency for Health Care Policy and Research.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Behavior Therapy; C | 1994 |
The effect of garlic extract on human metabolism of acetaminophen.
Topics: Acetaminophen; Adult; Allyl Compounds; Carcinogens; Garlic; Half-Life; Humans; Inactivation, Metabol | 1994 |
Hair opiates during pain treatment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Humans | 1997 |
Is the WHO analgesic ladder for cancer pain management appropriate for rheumatology patients?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Glucocortico | 1999 |
N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Expectorants; Heart Diseases; Humans; Neoplasms; Respirato | 2000 |
NCCN Practice Guidelines for Cancer Pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Neoplasms; Pain; Pain Measureme | 2000 |
Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice.
Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzene; Carcinogens; Cyt | 2001 |
Reaction time in cancer patients receiving peripherally acting analgesics alone or in combination with opioids.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Hum | 1992 |
Drug therapy in cancer pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Neop | 1991 |
Drug management of pain in cancer patients.
Topics: Acetaminophen; Humans; Neoplasms; Pain; Palliative Care | 1985 |
[3-step pharmacologic treatment of pain in cancer. Preliminary experience in Chile].
Topics: Acetaminophen; Adult; Analgesics; Chile; Codeine; Drug Administration Schedule; Female; Follow-Up St | 1988 |
[Therapy of pain caused by gastrointestinal tumors].
Topics: Acetaminophen; Aspirin; Bone Diseases; Dipyrone; Humans; Injections, Epidural; Narcotics; Neoplasms; | 1987 |
[Paracetamol and cancer risk].
Topics: Acetaminophen; Humans; Neoplasms; Risk | 1986 |
Plasma glutathione in health and in patients with malignant disease.
Topics: Acetaminophen; Adult; Blood Preservation; Female; Glutathione; Humans; Male; Middle Aged; Neoplasms; | 1985 |
Subchronic and chronic effects of feeding of large amounts of acetaminophen in B6C3F1 mice.
Topics: Acetaminophen; Administration, Oral; Animals; Body Weight; Female; Liver; Male; Mice; Mice, Inbred S | 1985 |