Page last updated: 2024-10-22

acetaminophen and Autolysis, Dental Pulp

acetaminophen has been researched along with Autolysis, Dental Pulp in 8 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
" The purpose of this study was to compare the efficacy of intranasal ketorolac (Sprix; Egalet US Inc, Wayne, PA) with a combination of ibuprofen/acetaminophen in an acute pain model of untreated endodontic patients experiencing moderate to severe pain and symptomatic apical periodontitis."5.30Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation. ( Balzer, S; Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Watts, K, 2019)
"Success was defined as no or mild postoperative pain and no use of escape medication."2.82What is the Effect of No Endodontic Debridement on Postoperative Pain for Symptomatic Teeth with Pulpal Necrosis? ( Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Sebastian, R, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Watts, K1
Balzer, S1
Drum, M3
Nusstein, J3
Reader, A7
Fowler, S2
Beck, M7
Sebastian, R1
Wells, LK1
Nusstein, JM1
Modaresi, J1
Dianat, O1
Mozayeni, MA1
Nist, E1
Pickenpaugh, L1
Meyers, WJ1
Peterson, LJ1
Henry, M1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication : A Randomized Clinical Trial.[NCT05021809]Phase 460 participants (Anticipated)Interventional2021-07-25Recruiting
Effect on Initial Endodontic Treatment on Postoperative Pain in Symptomatic Teeth With Pulpal Necrosis[NCT01870973]108 participants (Actual)Interventional2013-03-31Completed
Effect of Preoperative, Single-dose Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Double-Blind Randomized Controlled Trial.[NCT03033147]72 participants (Actual)Interventional2019-10-18Completed
Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Randomized Controlled Trial[NCT03007342]78 participants (Anticipated)Interventional2017-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Percent of Patients With Success as Defined by no or Mild Pain as Analyzed on a VAS Scale and no Narcotic Use

"pain measurement as assessed on a visual analog scale and pain medication usage~definition of success = no or mild pain as analyzed on VAS scale and no narcotic use; analyzed by logistic regression~VAS scale is 0 to 170 mm with the higher numbers indicating more pain and less success." (NCT01870973)
Timeframe: each day for 5 days

Interventionpercentage of participants (Number)
Root Canal Treatment52
no Root Canal Treatment43

Trials

7 trials available for acetaminophen and Autolysis, Dental Pulp

ArticleYear
Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation.
    Journal of endodontics, 2019, Volume: 45, Issue:2

    Topics: Acetaminophen; Acute Pain; Administration, Intranasal; Administration, Oral; Adult; Dental Pulp Necr

2019
What is the Effect of No Endodontic Debridement on Postoperative Pain for Symptomatic Teeth with Pulpal Necrosis?
    Journal of endodontics, 2016, Volume: 42, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Debridement

2016
Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis.
    Journal of endodontics, 2011, Volume: 37, Issue:12

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

2011
The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2006, Volume: 102, Issue:3

    Topics: Acetaminophen; Administration, Oral; Analgesics; Analysis of Variance; Anesthesia, Dental; Anesthesi

2006
Effect of apical trephination on postoperative pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anti-Infla

2001
Effect of prophylactic amoxicillin on endodontic flare-up in asymptomatic, necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:1

    Topics: Acetaminophen; Adult; Amoxicillin; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Varianc

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2001, Volume: 27, Issue:2

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla

2001

Other Studies

1 other study available for acetaminophen and Autolysis, Dental Pulp

ArticleYear
Effect of drainage upon access on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
    Journal of endodontics, 2002, Volume: 28, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St

2002