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acetaminophen and Autoimmune Diabetes

acetaminophen has been researched along with Autoimmune Diabetes in 21 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effect of the erythromycin derivative EM523L on gastric emptying and postprandial insulin requirement in insulin-dependent diabetic patients with severe gastroparesis."9.08Erythromycin derivative improves gastric emptying and insulin requirement in diabetic patients with gastroparesis. ( Baba, T; Ishii, M; Kasai, F; Nakamura, T; Takebe, K, 1997)
"Infections in early life have been linked to type 1 diabetes (T1D) risk, but no previous study has comprehensively analysed exposure to antibiotics, acetaminophen and infections during pregnancy and early childhood in relation to offspring risk of T1D."7.88Antibiotics, acetaminophen and infections during prenatal and early life in relation to type 1 diabetes. ( Joner, G; Kahrs, CR; Mårild, K; Njølstad, PR; Skrivarhaug, T; Stene, LC; Størdal, K; Tapia, G, 2018)
" the proportional cumulative area under the curve of paracetamol) was utilized in diabetic patients in order to detect both gastroparesis and the influence of metoclopramide, a known prokinetic drug, on this condition."5.08The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis. ( Moncrieff, J; Snyman, JR; Sommers, DK; van Wyk, M, 1995)
"To evaluate the effect of the erythromycin derivative EM523L on gastric emptying and postprandial insulin requirement in insulin-dependent diabetic patients with severe gastroparesis."5.08Erythromycin derivative improves gastric emptying and insulin requirement in diabetic patients with gastroparesis. ( Baba, T; Ishii, M; Kasai, F; Nakamura, T; Takebe, K, 1997)
"Infections in early life have been linked to type 1 diabetes (T1D) risk, but no previous study has comprehensively analysed exposure to antibiotics, acetaminophen and infections during pregnancy and early childhood in relation to offspring risk of T1D."3.88Antibiotics, acetaminophen and infections during prenatal and early life in relation to type 1 diabetes. ( Joner, G; Kahrs, CR; Mårild, K; Njølstad, PR; Skrivarhaug, T; Stene, LC; Størdal, K; Tapia, G, 2018)
"Acetaminophen (APAP) can cause erroneously high readings in real-time continuous glucose monitoring (rtCGM) systems."2.87Resistance to Acetaminophen Interference in a Novel Continuous Glucose Monitoring System. ( Balo, AK; Calhoun, P; Hughes, J; Johnson, TK; Price, D, 2018)
" In C57BL/6J mice, streptozotocin caused a dosage dependent increase in fasting blood glucose (FBG), from 100 to >600mg/dl."1.35Acetaminophen normalizes glucose homeostasis in mouse models for diabetes. ( Clegg, DJ; D'Alessio, DA; Genter, MB; Kendig, EL; Schneider, SN; Shertzer, HG, 2008)
"The reliability of the serum acetaminophen (APAP) concentration at 45 min (C45) as a measure of gastric emptying (GE) has been evaluated using a pharmacokinetic simulation work."1.31[The validity of serum acetaminophen concentration at 45 min as an index of gastric emptying rate: a study based on pharmacokinetic theories]. ( Anjiki, H; Hattori, K; Ishii, T; Kuyama, Y; Obara, M; Saitoh, M; Sanaka, M; Takikawa, H; Yamamoto, T, 2002)
"Patients were classified as diabetic autonomic neuropathy positive or negative using five standardized haemodynamic reflex tests."1.31Evaluation of standard haemodynamic tests of autonomic function and HbA1c as predictors of delayed gastric emptying in patients with type 1 diabetes mellitus. ( Cooke, T; Duggan, PF; Lydon, A; Murray, C; O'Halloran, D; Shorten, GD, 2000)
"Phenacetin was removed from the German market in 1986 and was replaced mainly in analgesic compounds by acetaminophen."1.30Incidence of analgesic nephropathy in Berlin since 1983. ( Preuschof, L; Schwarz, A; Zellner, D, 1999)
"Five subjects with poorly controlled IDDM and six age-weight-matched control subjects were clamped at a mean plasma glucose concentration of approximately 9 mM and mean plasma insulin concentrations approximately 400 pM for 5 h."1.2913C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus. ( Cline, GW; Katz, LD; Magnusson, I; Rothman, DL; Shulman, GI, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's4 (19.05)18.2507
2000's7 (33.33)29.6817
2010's6 (28.57)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Veteikis, D2
Denham, D1
Lundgren, M1
Steed, LJ1
Tamura, R1
Jonsdottir, B1
Gesualdo, P1
Crouch, C1
Sjöberg, M1
Hansson, G1
Hagopian, WA1
Ziegler, AG1
Rewers, MJ1
Lernmark, Å1
Toppari, J1
She, JX1
Akolkar, B1
Krischer, JP1
Haller, MJ1
Elding Larsson, H1
Calhoun, P1
Johnson, TK1
Hughes, J1
Price, D1
Balo, AK1
Tapia, G1
Størdal, K1
Mårild, K1
Kahrs, CR1
Skrivarhaug, T1
Njølstad, PR1
Joner, G1
Stene, LC1
Schiavon, M1
Acciaroli, G1
Vettoretti, M1
Giaretta, A1
Visentin, R1
Simpson, RW1
Wlodarczyk, JH1
Lodefalk, M1
Aman, J1
Bang, P1
Sanaka, M1
Kuyama, Y1
Obara, M1
Yamamoto, T1
Ishii, T1
Saitoh, M1
Hattori, K1
Anjiki, H1
Takikawa, H1
Johansson, UB1
Eskils, J1
Adamson, U1
Elwin, CE1
Wredling, R1
Lins, PE1
Akhlaghi, F1
Patel, CG1
Zuniga, XP1
Halilovic, J1
Preis, IS1
Gohh, RY1
Jones, JG1
Fagulha, A1
Barosa, C1
Bastos, M1
Barros, L1
Baptista, C1
Caldeira, MM1
Carvalheiro, M1
Shertzer, HG1
Schneider, SN1
Kendig, EL1
Clegg, DJ1
D'Alessio, DA1
Genter, MB1
Cline, GW1
Rothman, DL1
Magnusson, I1
Katz, LD1
Shulman, GI1
van Wyk, M1
Sommers, DK1
Snyman, JR1
Moncrieff, J1
Ishii, M1
Nakamura, T1
Kasai, F1
Baba, T1
Takebe, K1
Schwarz, A1
Preuschof, L1
Zellner, D1
Lydon, A1
Murray, C1
Cooke, T1
Duggan, PF1
O'Halloran, D1
Shorten, GD1
Adithan, C1
Danda, D1
Swaminathan, RP1
Indhiresan, J1
Shashindran, CH1
Bapna, JS1
Chandrasekar, S1
Kaye, R1
Athreya, BH1
Kunzman, EE1
Baker, L1

Trials

6 trials available for acetaminophen and Autoimmune Diabetes

ArticleYear
Resistance to Acetaminophen Interference in a Novel Continuous Glucose Monitoring System.
    Journal of diabetes science and technology, 2018, Volume: 12, Issue:2

    Topics: Acetaminophen; Adolescent; Adult; Aged; Artifacts; Blood Glucose; Blood Glucose Self-Monitoring; Dia

2018
Transdermal Buprenorphine Relieves Neuropathic Pain: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial in Diabetic Peripheral Neuropathic Pain.
    Diabetes care, 2016, Volume: 39, Issue:9

    Topics: Acetaminophen; Administration, Cutaneous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid;

2016
Effects of fat supplementation on glycaemic response and gastric emptying in adolescents with Type 1 diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2008, Volume: 25, Issue:9

    Topics: Acetaminophen; Adolescent; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, T

2008
Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Area Under Curve; Diabetes Mellitus, Type 1; Diabete

2006
The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:9

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Diabetes Mellitus, Type 1; Diabetic Neuropathi

1995
Erythromycin derivative improves gastric emptying and insulin requirement in diabetic patients with gastroparesis.
    Diabetes care, 1997, Volume: 20, Issue:7

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Biomarkers; Diabetes Mellitus, Type 1; Erythromycin;

1997

Other Studies

15 other studies available for acetaminophen and Autoimmune Diabetes

ArticleYear
Antipyretics might occupy a narrow temporal position in aetiology of type 1 diabetes: Immunological and intestinal studies required.
    Medical hypotheses, 2020, Volume: 141

    Topics: Acetaminophen; Antipyretics; Autoimmune Diseases; Child, Preschool; Diabetes Mellitus, Type 1; Fever

2020
Effect of Repeated Doses of Acetaminophen on a Continuous Glucose Monitoring System with Permselective Membrane.
    Journal of diabetes science and technology, 2021, Volume: 15, Issue:2

    Topics: Acetaminophen; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Humans

2021
Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity.
    BMC pediatrics, 2017, 05-16, Volume: 17, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Auto

2017
Antibiotics, acetaminophen and infections during prenatal and early life in relation to type 1 diabetes.
    International journal of epidemiology, 2018, 10-01, Volume: 47, Issue:5

    Topics: Acetaminophen; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cohort Studies; Diabetes

2018
A Model of Acetaminophen Pharmacokinetics and its Effect on Continuous Glucose Monitoring Sensor Measurements.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2018, Volume: 2018

    Topics: Acetaminophen; Algorithms; Analgesics, Non-Narcotic; Blood Glucose; Blood Glucose Self-Monitoring; D

2018
Anthropogenic and temporal components in a complex trigger of type 1 diabetes suggest the active participation of antipyretics.
    Medical hypotheses, 2016, Volume: 93

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Antipyretics; Autoimmunity; Child; Child,

2016
[The validity of serum acetaminophen concentration at 45 min as an index of gastric emptying rate: a study based on pharmacokinetic theories].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2002, Volume: 99, Issue:12

    Topics: Acetaminophen; Diabetes Mellitus, Type 1; Gastric Emptying; Humans; Models, Theoretical

2002
A paracetamol-pasta test for assessing gastric emptying in healthy and diabetic subjects.
    Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:2

    Topics: Acetaminophen; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Dietary Carbohydrates; Eating;

2003
Noninvasive analysis of hepatic glycogen kinetics before and after breakfast with deuterated water and acetaminophen.
    Diabetes, 2006, Volume: 55, Issue:8

    Topics: Acetaminophen; Adult; Body Water; Deuterium; Diabetes Mellitus, Type 1; Fasting; Female; Food; Fruct

2006
Acetaminophen normalizes glucose homeostasis in mouse models for diabetes.
    Biochemical pharmacology, 2008, Mar-15, Volume: 75, Issue:6

    Topics: Acetaminophen; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; D

2008
13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:6

    Topics: Acetaminophen; Adult; Carbon Isotopes; Citric Acid Cycle; Diabetes Mellitus, Type 1; Female; Glucose

1994
Incidence of analgesic nephropathy in Berlin since 1983.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:1

    Topics: Acetaminophen; Age Factors; Aged; Analgesics; Berlin; Diabetes Mellitus, Type 1; Diabetes Mellitus,

1999
Evaluation of standard haemodynamic tests of autonomic function and HbA1c as predictors of delayed gastric emptying in patients with type 1 diabetes mellitus.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:2

    Topics: Absorption; Acetaminophen; Analgesics, Non-Narcotic; Area Under Curve; Autonomic Nervous System; Aut

2000
Effect of diabetes mellitus on salivary paracetamol elimination.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabe

1988
Antipyretics in patients with juvenile diabetes mellitus. Comparison of salicylate and a salicylate substitute (experimental preparation PAJ-102).
    American journal of diseases of children (1960), 1966, Volume: 112, Issue:1

    Topics: Acetaminophen; Adolescent; Aspirin; Blood Glucose; Child; Diabetes Mellitus, Type 1; Drug Administra

1966