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acetaminophen and Autism

acetaminophen has been researched along with Autism in 18 studies

Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.

Research Excerpts

ExcerptRelevanceReference
" The use of acetaminophen in babies and young children may be much more strongly associated with autism than its use during pregnancy, perhaps because of well-known deficiencies in the metabolic breakdown of pharmaceuticals during early development."8.95The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism. ( Bilbo, S; Gentry, L; Herbert, MR; Holzknecht, ZE; Hornik, CD; Lin, SS; Nevison, CD; Parker, W; Rao, R, 2017)
"Schultz et al (2008) raised the question whether regression into autism is triggered, not by the measles-mumps-rubella (MMR) vaccine, but by acetaminophen (Tylenol) given for its fever and pain."8.85Did acetaminophen provoke the autism epidemic? ( Good, P, 2009)
"Acetaminophen use in children has been associated with increased autism risk."7.76Can autism be triggered by acetaminophen activation of the endocannabinoid system? ( Schultz, ST, 2010)
"The present study was performed to determine whether acetaminophen (paracetamol) use after the measles-mumps-rubella vaccination could be associated with autistic disorder."7.74Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. ( Akshoomoff, NA; Ji, M; Klonoff-Cohen, HS; Macera, CA; Schultz, ST; Wingard, DL, 2008)
"Two toxins most implicated in the U."5.48Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). ( Good, P, 2018)
"Autism and autism spectrum disorders are enigmatic conditions that have their origins in the interaction of genes and environmental factors."5.36Similarities in features of autism and asthma and a possible link to acetaminophen use. ( Becker, KG; Schultz, ST, 2010)
" The use of acetaminophen in babies and young children may be much more strongly associated with autism than its use during pregnancy, perhaps because of well-known deficiencies in the metabolic breakdown of pharmaceuticals during early development."4.95The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism. ( Bilbo, S; Gentry, L; Herbert, MR; Holzknecht, ZE; Hornik, CD; Lin, SS; Nevison, CD; Parker, W; Rao, R, 2017)
"Schultz et al (2008) raised the question whether regression into autism is triggered, not by the measles-mumps-rubella (MMR) vaccine, but by acetaminophen (Tylenol) given for its fever and pain."4.85Did acetaminophen provoke the autism epidemic? ( Good, P, 2009)
" 2018;187(8):1817-1827) conducted a meta-analysis of the association between in utero acetaminophen exposure and risks of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD)."3.96Invited Commentary: The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology. ( Gilman, SE; Hornig, M, 2020)
"Acetaminophen use in children has been associated with increased autism risk."3.76Can autism be triggered by acetaminophen activation of the endocannabinoid system? ( Schultz, ST, 2010)
"The present study was performed to determine whether acetaminophen (paracetamol) use after the measles-mumps-rubella vaccination could be associated with autistic disorder."3.74Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. ( Akshoomoff, NA; Ji, M; Klonoff-Cohen, HS; Macera, CA; Schultz, ST; Wingard, DL, 2008)
"Autism is a collection of behavioral symptoms characterized by dysfunction in social interaction and communication in affected children."2.41Autism and gastrointestinal symptoms. ( Horvath, K; Perman, JA, 2002)
"Two toxins most implicated in the U."1.48Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). ( Good, P, 2018)
"Autism and autism spectrum disorders are enigmatic conditions that have their origins in the interaction of genes and environmental factors."1.36Similarities in features of autism and asthma and a possible link to acetaminophen use. ( Becker, KG; Schultz, ST, 2010)
"Parents of autistic children and autism support groups often report that autistic episodes are exacerbated when the children eat certain foodstuffs such as dairy products, chocolates, wheat, corn sugar, apples, and bananas."1.30Sulphation deficit in "low-functioning" autistic children: a pilot study. ( Alberti, A; Elia, M; Pirrone, P; Romano, C; Waring, RH, 1999)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's5 (27.78)29.6817
2010's10 (55.56)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Masarwa, R2
Perlman, A2
Levine, H2
Matok, I2
Gilman, SE1
Hornig, M1
Parker, W1
Hornik, CD1
Bilbo, S1
Holzknecht, ZE1
Gentry, L1
Rao, R1
Lin, SS1
Herbert, MR1
Nevison, CD1
Saeedan, AS1
Singh, I1
Ansari, MN1
Singh, M1
Rawat, JK1
Devi, U1
Gautam, S1
Yadav, RK1
Kaithwas, G1
Good, P2
Damkier, P1
Olsen, J1
Liew, Z1
Cox, AR1
McDowell, S1
Becker, KG1
Schultz, ST3
Miller, AL1
Turlejski, K1
Ghanizadeh, A1
Klonoff-Cohen, HS1
Wingard, DL1
Akshoomoff, NA1
Macera, CA1
Ji, M1
Alberti, A1
Pirrone, P1
Elia, M1
Waring, RH1
Romano, C1
Horvath, K1
Perman, JA1

Reviews

3 reviews available for acetaminophen and Autism

ArticleYear
The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism.
    The Journal of international medical research, 2017, Volume: 45, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspartame; Autistic Disorder; Child; Child, Preschool; Fema

2017
Did acetaminophen provoke the autism epidemic?
    Alternative medicine review : a journal of clinical therapeutic, 2009, Volume: 14, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Autistic Disorder; Centers for Disease Control and

2009
Autism and gastrointestinal symptoms.
    Current gastroenterology reports, 2002, Volume: 4, Issue:3

    Topics: Acetaminophen; Autistic Disorder; Child; Gastritis; Gastrointestinal Diseases; Helicobacter Infectio

2002

Other Studies

15 other studies available for acetaminophen and Autism

ArticleYear
Masarwa et al. Respond to "The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology".
    American journal of epidemiology, 2020, 01-31, Volume: 189, Issue:1

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Cohort Studies; Fem

2020
Invited Commentary: The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology.
    American journal of epidemiology, 2020, 01-31, Volume: 189, Issue:1

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Autistic Dis

2020
Effect of early natal supplementation of paracetamol on attenuation of exotoxin/endotoxin induced pyrexia and precipitation of autistic like features in albino rats.
    Inflammopharmacology, 2018, Volume: 26, Issue:4

    Topics: Acetaminophen; Animals; Animals, Newborn; Antipyretics; Autistic Disorder; Behavior, Animal; Diphthe

2018
Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup).
    Clinical nutrition ESPEN, 2018, Volume: 23

    Topics: Acetaminophen; Amoxicillin-Potassium Clavulanate Combination; Androgens; Aromatase; Aromatase Inhibi

2018
FOUR AUTHORS REPLY.
    American journal of epidemiology, 2018, 12-01, Volume: 187, Issue:12

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Cohort Studi

2018
RE: "PRENATAL EXPOSURE TO ACETAMINOPHEN AND RISK FOR ATTENTION DEFICIT HYPERACTIVITY DISORDER AND AUTISTIC SPECTRUM DISORDER: A SYSTEMATIC REVIEW, META-ANALYSIS, AND META-REGRESSION ANALYSIS OF COHORT STUDIES".
    American journal of epidemiology, 2018, 12-01, Volume: 187, Issue:12

    Topics: Acetaminophen; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Child; Cohort Studi

2018
Commentary: Acetaminophen use in pregnancy and neurodevelopment: attention function and autism spectrum symptoms.
    International journal of epidemiology, 2016, 12-01, Volume: 45, Issue:6

    Topics: Acetaminophen; Attention; Autistic Disorder; Child; Child Development Disorders, Pervasive; Female;

2016
A response to the article on the association between paracetamol/acetaminophen: use and autism by Stephen T. Schultz.
    Autism : the international journal of research and practice, 2009, Volume: 13, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Autistic Disorder; Bias; Case-Control Studies; Child, Presc

2009
Similarities in features of autism and asthma and a possible link to acetaminophen use.
    Medical hypotheses, 2010, Volume: 74, Issue:1

    Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Autistic Disorder; Child

2010
Liver damage from chronic acetaminophen dosing is dangerous, but not the only risk.
    Alternative medicine review : a journal of clinical therapeutic, 2009, Volume: 14, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Autistic Disorder; Chemical and Drug Induced Liver I

2009
Can autism be triggered by acetaminophen activation of the endocannabinoid system?
    Acta neurobiologiae experimentalis, 2010, Volume: 70, Issue:2

    Topics: Acetaminophen; Autistic Disorder; Cannabinoid Receptor Modulators; Child; Child, Preschool; Endocann

2010
Focus on autism.
    Acta neurobiologiae experimentalis, 2010, Volume: 70, Issue:2

    Topics: Acetaminophen; Amygdala; Autistic Disorder; Child; Child, Preschool; Exploratory Behavior; Gastroint

2010
Acetaminophen may mediate oxidative stress and neurotoxicity in autism.
    Medical hypotheses, 2012, Volume: 78, Issue:2

    Topics: Acetaminophen; Animals; Apoptosis; Autistic Disorder; Cytochrome P-450 CYP2E1; Humans; Mice; Nervous

2012
Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey.
    Autism : the international journal of research and practice, 2008, Volume: 12, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Autistic Disorder;

2008
Sulphation deficit in "low-functioning" autistic children: a pilot study.
    Biological psychiatry, 1999, Aug-01, Volume: 46, Issue:3

    Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Autistic Disorder; Child;

1999